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1. 发明申请

WO2007025302A2 SUTURING APPARATUS AND METHODS 审中-公开
标题翻译：缝合设备和方法
公开(公告)号：WO2007025302A2
公开(公告)日：2007-03-01
申请号：PCT/US2006/033730
申请日：2006-08-28
申请人： G-SURGE MEDICAL SOLUTIONS, INC. , MCLAUGHLIN, Glen, W. , AZIZ, Imraan , SONGER, Ron , CHRISTIAN, Jeffrey
发明人： MCLAUGHLIN, Glen, W. , AZIZ, Imraan , SONGER, Ron , CHRISTIAN, Jeffrey
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0625 , A61B2017/00637 , A61B2017/00663 , A61B2017/0417 , A61B2017/0454 , A61B2017/0458 , A61B2017/0472 , A61B2017/0475
摘要： Embodiments of the invention provide methods and apparatus for suturing tissue penetrations made during minimally invasive surgery. One embodiment of an apparatus for suturing tissue penetrations comprises a shaft, suture capture surface coupled to the shaft and at least one pair of needles or other penetrating members advanceable from the shaft. The shaft can be detachably coupled to a handpiece. The surface has a deployed and a non-deployed configuration and is configured to capture a suture in the deployed configuration and retain it in the non-deployed configuration. The surface can be deployed by a frame or other expandable structure. The penetrating members are configured to be coupled to a suture and are advanceable from the shaft by an advancement member or other means to deliver a suture end portion to the deployed surface. Sutures can be contained in a replaceable cartridge detachably coupled to the apparatus.
摘要翻译：本发明的实施例提供用于缝合在微创手术期间进行的组织穿透的方法和设备。用于缝合组织穿透的装置的一个实施例包括轴，与该轴连接的缝合线捕获表面以及从该轴可推进的至少一对针或其他穿透构件。轴可以可拆卸地连接到手持件。该表面具有展开和非展开配置，并被配置为捕获展开配置中的缝线并将其保持在未展开配置中。表面可以通过框架或其他可展开结构展开。穿透构件被构造成联接到缝合线并且可通过推进构件或其他装置从轴推进以将缝合线端部部分输送到展开表面。缝线可以容纳在可拆卸地连接到设备的可更换筒中。

2. 发明申请

WO2012129576A3 SYSTEM AND METHOD FOR BIPHASIC TRANSDERMAL IONTOPHREOTIC DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：用于治疗药物的双向超声心动图输送的系统和方法
公开(公告)号：WO2012129576A3
公开(公告)日：2012-12-27
申请号：PCT/US2012030633
申请日：2012-03-26
申请人： INCUBE LABS LLC , IMRAN MIR , HASHIM MIR , MCLAUGHLIN GLEN , ARASTU HUMA , VAIDYANATHAN REKHA , HARRIS JOEL , KORUPOLU RADHIKA , MANGOGNA ANDREW , ONG CHANG , PATEL SANJAY , WANG LU , WILLIAMS TIMOTHY
发明人： IMRAN MIR , HASHIM MIR , MCLAUGHLIN GLEN , ARASTU HUMA , VAIDYANATHAN REKHA , HARRIS JOEL , KORUPOLU RADHIKA , MANGOGNA ANDREW , ONG CHANG , PATEL SANJAY , WANG LU , WILLIAMS TIMOTHY
IPC分类号： A61N1/30 , A61K9/70 , A61N1/04 , A61N1/36
CPC分类号： A61N1/325 , A61K9/0009 , A61K9/0014 , A61K31/4178 , A61K31/4468 , A61K31/454 , A61K31/5415 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/30 , A61N1/303
摘要： Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.
摘要翻译：各种实施方案提供了用于治疗剂的双相离子电渗透皮递送的方法和系统。用于这种传送的方法的实施例包括将至少一个电极组件定位成与患者的皮肤电连通。组合物包括包含被动地扩散入皮肤的治疗剂的溶液。使用具有例如极性和大小的特性的第一电流，在第一时段期间，将剂量的药剂从组合物输送到皮肤中，以将药剂排斥出组合体。在第二时段期间，使用具有吸引剂的特性的第二电流将试剂保持在组合中，使得药剂递送到皮肤中最小化。可以根据患者的输入要求递送剂量。实施方案可以用于递送由不希望的被动扩散引起不利影响的试剂。

3. 发明申请

WO2007025302A3 SUTURING APPARATUS AND METHODS 审中-公开
标题翻译：装备装置和方法
公开(公告)号：WO2007025302A3
公开(公告)日：2007-11-15
申请号：PCT/US2006033730
申请日：2006-08-28
申请人： SURGE MEDICAL SOLUTIONS INC G , MCLAUGHLIN GLEN W , AZIZ IMRAAN , SONGER RON , CHRISTIAN JEFFREY , SINGHAL ANIL
发明人： MCLAUGHLIN GLEN W , AZIZ IMRAAN , SONGER RON , CHRISTIAN JEFFREY , SINGHAL ANIL
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0625 , A61B2017/00637 , A61B2017/00663 , A61B2017/0417 , A61B2017/0454 , A61B2017/0458 , A61B2017/0472 , A61B2017/0475
摘要： Embodiments of the invention provide methods and apparatus for suturing tissue penetrations made during minimally invasive surgery. One embodiment of an apparatus for suturing tissue penetrations comprises a shaft, suture capture surface coupled to the shaft and at least one pair of needles or other penetrating members advanceable from the shaft. The shaft can be detachably coupled to a handpiece. The surface has a deployed and a non-deployed configuration and is configured to capture a suture in the deployed configuration and retain it in the non-deployed configuration. The surface can be deployed by a frame or other expandable structure. The penetrating members are configured to be coupled to a suture and are advanceable from the shaft by an advancement member or other means to deliver a suture end portion to the deployed surface. Sutures can be contained in a replaceable cartridge detachably coupled to the apparatus.
摘要翻译：本发明的实施例提供了用于在微创手术期间缝合组织穿透的方法和装置。用于缝合组织穿透的装置的一个实施例包括连接到轴的轴，缝合线捕获表面和可从轴可推进的至少一对针或其它穿透构件。轴可以可拆卸地联接到手持件。表面具有已部署和未部署的配置，并配置为捕获部署配置中的缝合线并将其保留在未部署的配置中。表面可以通过框架或其他可扩展结构来展开。穿透构件被构造成联接到缝合线并且可以通过前进构件或其他装置从轴前进，以将缝合线端部部分递送到展开的表面。缝合线可以容纳在可拆卸地联接到该装置的可替换的盒中。

4. 发明申请

WO2012109394A2 APPARATUS, SYSTEM AND METHODS FOR PHOTOACOUSTIC DETECTION OF DEEP VEIN THROMBOSIS 审中-公开
标题翻译：用于深度检测深度血栓形成的装置，系统和方法
公开(公告)号：WO2012109394A2
公开(公告)日：2012-08-16
申请号：PCT/US2012024384
申请日：2012-02-08
申请人： INCUBE LABS LLC , IMRAN MIR , MCLAUGHLIN GLEN
发明人： IMRAN MIR , MCLAUGHLIN GLEN
IPC分类号： A61B5/00 , A61B5/145 , A61B5/1455 , A61B8/00
CPC分类号： A61B5/0095 , A61B5/02028 , A61B8/0891
摘要： Embodiments of the invention provide apparatus, systems and methods for the detection of deep vein thrombosis (DVT) using photoacoustic measurement of hemoglobin in different states of oxygenation within tissue. One embodiment of a system for DVT detection comprises at least a first and second light source that emit light at first and second wavelengths, an acoustic transducer, a data converter and a processor. The first and second light sources are directed on the patient's skin to produce a photoacoustic signal (PS) correlated to an amount of absorbance of the first and second wavelengths by a target region of tissue beneath the patient's skin. The acoustic transducer detects the PS and transduces it into an electrical signal which is correlated to the PS. The data converter converts the electrical signal into a digital signal which is analyzed by the processor to detect the presence of DVT within the target region.
摘要翻译：本发明的实施例提供了使用组织内不同氧合状态的血红蛋白的光声测量来检测深静脉血栓形成（DVT）的装置，系统和方法。用于DVT检测的系统的一个实施例包括至少第一和第二光源，其发射第一和第二波长的光，声换能器，数据转换器和处理器。第一和第二光源被引导到患者的皮肤上，以产生与患者皮肤下面的组织的目标区域与第一和第二波长的吸光度相关的光声信号（PS）。声换能器检测PS并将其转换成与PS相关的电信号。数据转换器将电信号转换成由处理器分析的数字信号，以检测目标区域内DVT的存在。

5. 发明申请

WO2008051738A2 CONTROL OF USER INTERFACES AND DISPLAYS FOR PORTABLE ULTRASOUND UNIT AND DOCKING STATION 审中-公开
标题翻译：用户界面的控制和便携式超声波单元和锁定站的显示
公开(公告)号：WO2008051738A2
公开(公告)日：2008-05-02
申请号：PCT/US2007081253
申请日：2007-10-12
申请人： ZONARE MEDICAL SYSTEMS INC , STEINS ROBERT W , MCLAUGHLIN GLEN W
发明人： STEINS ROBERT W , MCLAUGHLIN GLEN W
IPC分类号： G06F1/16
CPC分类号： G06F1/1616 , A61B8/4405 , A61B8/4433 , A61B8/546 , G06F1/1632
摘要： Embodiments of the present invention provide ways for controlling a plurality of visual displays and a plurality of user interfaces for a portable ultrasound device which can be mounted to different docking stations or carts to provide and enhance different functionalities and features. In one embodiment, a portable ultrasound device comprises a portable housing; a display control module configured to control a plurality of visual displays, at least one of the visual displays being selectively configurable to provide a user interface display on the visual display for user interface control, at least one of the visual displays being selectively configurable to view an ultrasound image; and a plurality of user interfaces, at least one of the plurality of user interfaces being a separate user interface which is not integrally formed with the portable housing.
摘要翻译：本发明的实施例提供了用于控制便携式超声波装置的多个视觉显示器和多个用户界面的方法，所述便携式超声波装置可以安装到不同的对接站或推车以提供和增强不同的功能和特征。在一个实施例中，便携式超声波装置包括便携式外壳; 显示控制模块，被配置为控制多个视觉显示器，所述视觉显示器中的至少一个可选择性地被配置为在视觉显示器上提供用户界面显示以进行用户界面控制，所述视觉显示器中的至少一个可选择性地配置为观看超声图像; 以及多个用户界面，所述多个用户界面中的至少一个是与所述便携式外壳不一体形成的单独的用户界面。

6. 发明申请

WO2012109394A3 APPARATUS, SYSTEM AND METHODS FOR PHOTOACOUSTIC DETECTION OF DEEP VEIN THROMBOSIS 审中-公开
公开(公告)号：WO2012109394A3
公开(公告)日：2012-08-16
申请号：PCT/US2012/024384
申请日：2012-02-08
申请人： INCUBE LABS, LLC , IMRAN, Mir , MCLAUGHLIN, Glen
发明人： IMRAN, Mir , MCLAUGHLIN, Glen
IPC分类号： A61B5/00 , A61B5/145 , A61B8/00 , A61B5/1455
摘要： Embodiments of the invention provide apparatus, systems and methods for the detection of deep vein thrombosis (DVT) using photoacoustic measurement of hemoglobin in different states of oxygenation within tissue. One embodiment of a system for DVT detection comprises at least a first and second light source that emit light at first and second wavelengths, an acoustic transducer, a data converter and a processor. The first and second light sources are directed on the patient's skin to produce a photoacoustic signal (PS) correlated to an amount of absorbance of the first and second wavelengths by a target region of tissue beneath the patient's skin. The acoustic transducer detects the PS and transduces it into an electrical signal which is correlated to the PS. The data converter converts the electrical signal into a digital signal which is analyzed by the processor to detect the presence of DVT within the target region.

7. 发明申请

WO2012129576A2 SYSTEM AND METHOD FOR BIPHASIC TRANSDERMAL IONTOPHREOTIC DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：系统和方法用于治疗药物的双向透皮递送
公开(公告)号：WO2012129576A2
公开(公告)日：2012-09-27
申请号：PCT/US2012/030633
申请日：2012-03-26
申请人： INCUBE LABS, LLC , IMRAN, Mir , HASHIM, Mir , MCLAUGHLIN, Glen , ARASTU, Huma , VAIDYANATHAN, Rekha , HARRIS, Joel , KORUPOLU, Radhika , MANGOGNA, Andrew , ONG, Chang , PATEL, Sanjay , WANG, Lu , WILLIAMS, Timothy
发明人： IMRAN, Mir , HASHIM, Mir , MCLAUGHLIN, Glen , ARASTU, Huma , VAIDYANATHAN, Rekha , HARRIS, Joel , KORUPOLU, Radhika , MANGOGNA, Andrew , ONG, Chang , PATEL, Sanjay , WANG, Lu , WILLIAMS, Timothy
IPC分类号： A61N1/30 , A61N1/36 , A61N1/04 , A61K9/70
CPC分类号： A61N1/325 , A61K9/0009 , A61K9/0014 , A61K31/4178 , A61K31/4468 , A61K31/454 , A61K31/5415 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/30 , A61N1/303
摘要： Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.
摘要翻译：各种实施方案提供用于治疗剂的双相离子电渗透皮递送的方法和系统。用于这种递送的方法的实施例包括将至少一个电极组件定位成与患者的皮肤电通信。该组件包括包含被动扩散到皮肤中的治疗剂的溶液。在第一阶段期间，使用具有例如极性和大小等特征的第一电流将剂量的药剂从组件递送到皮肤中，以将药剂排出组件。在第二阶段期间，具有吸引药剂的特征的第二电流被用于将药剂保持在组件中，使得药剂递送到皮肤中被最小化。一剂药剂可以通过来自患者的输入按需递送。实施例可以用于递送引起不希望的被动扩散的不利影响的试剂。

8. 发明申请

WO2008051738A3 CONTROL OF USER INTERFACES AND DISPLAYS FOR PORTABLE ULTRASOUND UNIT AND DOCKING STATION 审中-公开
公开(公告)号：WO2008051738A3
公开(公告)日：2008-05-02
申请号：PCT/US2007/081253
申请日：2007-10-12
申请人： ZONARE MEDICAL SYSTEMS, INC. , STEINS, Robert, W. , MCLAUGHLIN, Glen, W.
发明人： STEINS, Robert, W. , MCLAUGHLIN, Glen, W.
IPC分类号： G06F1/16
摘要： Embodiments of the present invention provide ways for controlling a plurality of visual displays and a plurality of user interfaces for a portable ultrasound device which can be mounted to different docking stations or carts to provide and enhance different functionalities and features. In one embodiment, a portable ultrasound device comprises a portable housing; a display control module configured to control a plurality of visual displays, at least one of the visual displays being selectively configurable to provide a user interface display on the visual display for user interface control, at least one of the visual displays being selectively configurable to view an ultrasound image; and a plurality of user interfaces, at least one of the plurality of user interfaces being a separate user interface which is not integrally formed with the portable housing.

9. 发明申请

WO2004080364A3 PORTABLE ULTRASOUND UNIT AND DOCKING STATION 审中-公开
标题翻译：便携式超声波单元和对接站
公开(公告)号：WO2004080364A3
公开(公告)日：2004-12-23
申请号：PCT/US2004006959
申请日：2004-03-03
申请人： ZONARE MEDICAL SYSTEMS INC , SMITH SCOTT F , HAYDEN MICHAEL E , FELIX IAN , DEBUSSCHERE DEREK , MCLAUGHLIN GLEN
发明人： SMITH SCOTT F , HAYDEN MICHAEL E , FELIX IAN , DEBUSSCHERE DEREK , MCLAUGHLIN GLEN
IPC分类号： A61B17/22 , A61B19/00 , A61B19/02 , G06F1/16
CPC分类号： G01S15/899 , A61B5/024 , A61B5/08 , A61B5/145 , A61B5/7275 , A61B8/00 , A61B8/4209 , A61B8/4405 , A61B8/4427 , A61B8/4433 , A61B8/462 , A61B8/467 , A61B8/468 , A61B8/546 , A61B8/56 , A61B17/2251 , A61B50/10 , A61B50/13 , A61B90/36 , A61B2017/00017 , A61B2017/00199 , A61B2017/00225 , A61B2090/378 , A61B2560/0456 , G01S7/52082 , G06F1/1632
摘要： A portable ultrasound unit and docking cart for the unit are provided. When the portable unit is mounted to the docking cart, the docking cart transforms the portable unit into a cart-based system with enhanced features and functionality such as improved ergonomics, ease of use, a larger display format, external communications connectivity, multiple transducer connections, and increased data processing capabilities. A clinician display and patient display may be provided on the cart. Communications circuitry in the docking cart may be used to support communications between the docking cart's processor and external networks and devices. The docking cart may receive physiological signals such as cardiac signals and may use this information to synchronize ultrasound imaging operations with a patient's physiological condition. Adjustable user interface controls, data handling features, security features, power control functions, and thermal management capabilities may be provided in the docking cart.
摘要翻译：提供便携式超声波单元和对接单元。当便携式单元安装到对接小车上时，对接小车将便携式单元转变成基于购物车的系统，其具有增强的特征和功能，例如改进的人体工程学，易用性，更大的显示格式，外部通信连接性，多个换能器连接并增加了数据处理能力。可以在购物车上提供临床医生显示器和患者显示器。对接小车中的通信电路可用于支持对接小车的处理器与外部网络和设备之间的通信。对接小车可以接收诸如心脏信号的生理信号并且可以使用该信息来使超声成像操作与患者的生理状况同步。对接车中可以提供可调节的用户界面控件，数据处理功能，安全功能，电源控制功能和散热管理功能。

10. 发明申请

WO2004080364A2 PORTABLE ULTRASOUND UNIT AND DOCKING STATION 审中-公开
标题翻译：便携式超声波单元和锁定站
公开(公告)号：WO2004080364A2
公开(公告)日：2004-09-23
申请号：PCT/US2004/006959
申请日：2004-03-03
申请人： ZONARE MEDICAL SYSTEMS, INC. , SMITH, Scott, F. , HAYDEN, Michael, E. , FELIX, Ian , DEBUSSCHERE, Derek , MCLAUGHLIN, Glen
发明人： SMITH, Scott, F. , HAYDEN, Michael, E. , FELIX, Ian , DEBUSSCHERE, Derek , MCLAUGHLIN, Glen
IPC分类号： A61G
CPC分类号： G01S15/899 , A61B5/024 , A61B5/08 , A61B5/145 , A61B5/7275 , A61B8/00 , A61B8/4209 , A61B8/4405 , A61B8/4427 , A61B8/4433 , A61B8/462 , A61B8/467 , A61B8/468 , A61B8/546 , A61B8/56 , A61B17/2251 , A61B50/10 , A61B50/13 , A61B90/36 , A61B2017/00017 , A61B2017/00199 , A61B2017/00225 , A61B2090/378 , A61B2560/0456 , G01S7/52082 , G06F1/1632
摘要： A portable ultrasound unit and docking cart for the unit are provided. When the portable unit is mounted to the docking cart, the docking cart transforms the portable unit into a cart-based system with enhanced features and functionality such as improved ergonomics, ease of use, a larger display format, external communications connectivity, multiple transducer connections, and increased data processing capabilities. A clinician display and patient display may be provided on the cart. Communications circuitry in the docking cart may be used to support communications between the docking cart's processor and external networks and devices. The docking cart may receive physiological signals such as cardiac signals and may use this information to synchronize ultrasound imaging operations with a patient's physiological condition. Adjustable user interface controls, data handling features, security features, power control functions, and thermal management capabilities may be provided in the docking cart.
摘要翻译：提供了用于该装置的便携式超声单元和对接车。当便携式装置安装到对接车时，对接车将便携式装置转换成具有增强的特征和功能的基于购物车的系统，例如改进的人体工程学，易于使用，更大的显示格式，外部通信连接性，多个换能器连接，并增加了数据处理能力。可以在推车上提供临床医生显示和患者显示。对接车中的通信电路可用于支持对接车的处理器与外部网络和设备之间的通信。对接车可以接收诸如心脏信号的生理信号，并且可以使用该信息来将超声成像操作与患者的生理状况同步。可以在对接车中提供可调整的用户界面控制，数据处理特征，安全特征，功率控制功能和热管理功能。

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