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1. 发明申请

US20140037062A1 IMAGE GUIDED RADIATION THERAPY 审中-公开
标题翻译：图像指导辐射治疗
公开(公告)号：US20140037062A1
公开(公告)日：2014-02-06
申请号：US13563788
申请日：2012-08-01
申请人： Daniel Robert ELGORT , Lucian Remus ALBU , Clemens BOS
发明人： Daniel Robert ELGORT , Lucian Remus ALBU , Clemens BOS
IPC分类号： A61B6/08
CPC分类号： G01R33/4808 , A61B5/055 , A61B5/70 , A61N5/1049 , A61N2005/1055
摘要： An image guided radiation therapy system comprises a radiation source to generate radiation. Radiation optics forms a therapeutic radiation beam from the therapeutic radiation from the radiation source. An imaging system forms an image of a target zone to control the radiation optics to direct the therapeutic radiation beam onto the target zone. The radiation optics is provided with an optics module configured to generate an imaging photonic beam endowed with optical angular momentum. The imaging system comprises a magnetic resonance assembly to receive magnetic resonance signals the from the target zone generated by imaging photonic beam endowed with optical angular momentum.
摘要翻译：图像引导放射治疗系统包括产生辐射的辐射源。辐射光学器件形成来自辐射源的治疗辐射的治疗辐射束。成像系统形成目标区域的图像，以控制辐射光学器件将治疗辐射束引导到目标区域上。辐射光学器件设置有被配置为产生具有光学角动量的成像光子束的光学模块。该成像系统包括一个磁共振组件，用于接收来自由具有光学角动量的成像光子束产生的目标区域的磁共振信号。

2. 发明授权

US08636980B2 MRI thermometry combined with hyperpolarisation device using photons with orbital angular momentum 失效
标题翻译： MRI测温结合使用具有轨道角动量的光子的超极化装置
公开(公告)号：US08636980B2
公开(公告)日：2014-01-28
申请号：US13376847
申请日：2010-06-14
申请人： Daniel R. Elgort , Lucian Remus Albu
发明人： Daniel R. Elgort , Lucian Remus Albu
IPC分类号： A61B5/055
CPC分类号： G01R33/4804 , A61B5/01 , A61B5/055 , G01N24/006 , G01R33/282 , G01R33/62
摘要： A magnetic resonance examination system comprises an RF-system for inducing resonance in polarized dipoles and receiving magnetic resonance signals from an object to be examined. A thermometry module dervies a temperature distribution of the object to be examined from the magnetic resonance signals. The magnetic resonance examination system further comprises a photonic-based hyperpolarization device with a photonic source for emitting electromagnetic radiation, a moder converter, such as a phase hologram to impart orbital angular momentum to the electromagnetic radiation and via spatial filter to select from the phase hologram a diffracted photonic beam endowed with orbital angular momentum for polarizing the dipoles via transferred orbital angular momentum.
摘要翻译：磁共振检查系统包括用于在极化偶极子中诱发共振的RF系统，并接收来自被检查物体的磁共振信号。温度测量模块从磁共振信号中得出待检测对象的温度分布。磁共振检查系统还包括具有用于发射电磁辐射的光子源的基于光子的超极化装置，诸如相位全息图的慢速转换器，以向电磁辐射赋予轨道角动量，并且经由空间滤波器从相位全息图中选择衍射光子束具有轨道角动量，用于通过转移的轨道角动量极化偶极子。

3. 发明授权

US08611982B2 Active device tracking using light with orbital angular momentum to hyperpolarized MRI 失效
标题翻译：有源器件跟踪使用具有轨道角动量的光与超极化MRI
公开(公告)号：US08611982B2
公开(公告)日：2013-12-17
申请号：US13131881
申请日：2009-11-05
申请人： Daniel R. Elgort , Lucian Remus Albu
发明人： Daniel R. Elgort , Lucian Remus Albu
IPC分类号： G01V3/00
CPC分类号： A61B34/20 , A61B5/055 , A61B5/06 , A61B2034/2051 , A61B2090/373 , A61B2090/374
摘要： One or more light beam endowed with photonic orbital angular momentum generating devices are mounted at preselected locations on an insertable instrument to hyperpolarize nuclear magnetic dipoles in a region of interest. The hyperpolarized nuclear magnetic dipoles are caused to resonate, generating magnetic resonance signals. A controller controls gradient coils to induce a magnetic field gradient across the region of interest, such that the frequency of the resonance signals is indicative of spatial positions. A frequency-to-position decoder converts the resonance signal frequencies into spatial positions. A video processor combines the spatial positions and a portion of a diagnostic image from a diagnostic image memory into a combined image which depicts the location of the region of interest or a portion of the instrument marked on the diagnostic image and displays the combined image on a monitor.
摘要翻译：具有光子轨道角动量产生装置的一个或多个光束被安装在可插入仪器上的预选位置处，以在感兴趣的区域中超极化核磁偶极子。引起超极化核磁偶极子共振，产生磁共振信号。控制器控制梯度线圈以在感兴趣区域上引起磁场梯度，使得谐振信号的频率指示空间位置。频率到位置解码器将谐振信号频率转换成空间位置。视频处理器将空间位置和来自诊断图像存储器的诊断图像的一部分组合成组合图像，该组合图像描绘了标记在诊断图像上的感兴趣区域或仪器的一部分的位置，并将组合图像显示在监控。

4. 发明授权

US06967638B2 Circuit and method for addressing multiple rows of a display in a single cycle 失效
标题翻译：用于在单个周期中寻址多行显示器的电路和方法
公开(公告)号：US06967638B2
公开(公告)日：2005-11-22
申请号：US10165905
申请日：2002-06-10
申请人： Peter J. Janssen , Lucian Remus Albu
发明人： Peter J. Janssen , Lucian Remus Albu
IPC分类号： G02F1/133 , G09G3/20 , G09G3/36
CPC分类号： G09G3/3674 , G09G3/20 , G09G3/3677 , G09G2310/0205 , G09G2310/0251 , G09G2310/0267
摘要： A row addressing circuit and method for addressing multiple rows of a visual display in a single cycle. The circuit comprises: a decoder coupled to a plurality of signal lines, wherein the decoder includes a system for decoding a row select address, a first pre-write address and a second pre-write address and selecting three corresponding signals lines during the single cycle; and wherein each of the plurality of signal lines is further coupled to a dedicated set of latches, wherein each set of latches includes a row select latch, a first pre-write latch, and a second pre-write latch.
摘要翻译：用于在单个周期中寻址多行视觉显示的行寻址电路和方法。电路包括：耦合到多个信号线的解码器，其中解码器包括用于解码行选择地址的系统，第一预写地址和第二预写地址，并且在单周期期间选择三个对应的信号线 ; 并且其中所述多个信号线中的每一个还被耦合到专用锁存器组，其中每组锁存器包括行选择锁存器，第一预写锁存器和第二预写锁存器。

5. 发明授权

US06384817B1 Apparatus for applying voltages to individual columns of pixels in a color electro-optic display device 失效
标题翻译：用于向彩色电光显示装置中的各个像素列施加电压的装置
公开(公告)号：US06384817B1
公开(公告)日：2002-05-07
申请号：US09469455
申请日：1999-12-21
申请人： Peter J. Janssen , Lucian Remus Albu , John E. Dean
发明人： Peter J. Janssen , Lucian Remus Albu , John E. Dean
IPC分类号： G09G500
CPC分类号： G09G3/2011 , G02F1/13306 , G09G3/3685 , G09G2310/0259 , G09G2320/02
摘要： In an electro-optic display device, such as a liquid crystal display device which serves as a modulator for projected light, a global ramp generator is used in conjunction with track and hold circuits to convert incoming digital display signals to analog signals, and to address the individual pixels of the display device with such analog signals. A plurality of column drivers, each coupled to the ramp generator and to the pixels in a column of the display device, track and hold the ramp voltage signal when it reaches a value corresponding to the desired brightness level of a particular pixel in the respective column. At least one current source is provided, coupled to the signal source output, for supplying current to the signal source output, as needed, to compensate for switching the capacitive load of the column drivers on and off. As a result, transient voltages in the ramp signal are avoided.
摘要翻译：在诸如用作投影光的调制器的液晶显示装置的电光显示装置中，全局斜坡发生器与轨道和保持电路结合使用以将输入的数字显示信号转换为模拟信号，并且寻址具有这种模拟信号的显示装置的各个像素。每个耦合到斜坡发生器和显示装置的列中的像素的列驱动器当其达到对应于相应列中的特定像素的期望亮度水平的值时跟踪并保持斜坡电压信号。提供耦合到信号源输出的至少一个电流源，用于根据需要向信号源输出提供电流，以补偿对列驱动器的容性负载的开关。结果，避免了斜坡信号中的瞬态电压。

6. 发明授权

US08852155B2 Medicine reservoir for drug delivery device 有权
标题翻译：药物输送装置药库
公开(公告)号：US08852155B2
公开(公告)日：2014-10-07
申请号：US13390110
申请日：2010-08-09
申请人： Hans Zou , Jeff Shimizu , Lucian Remus Albu
发明人： Hans Zou , Jeff Shimizu , Lucian Remus Albu
IPC分类号： A61M5/178 , A61M31/00
CPC分类号： A61M31/00 , A61M31/002
摘要： A medicine reservoir (10) is provided for use with a drug delivery device (50). The medicine reservoir (10) is arranged for comprising a drug (13) and comprises a dispensing hole (15) for dispensing the drug (13) into an environment of the drug delivery device (50). The medicine reservoir (10) further comprises a deformable plug (14) which plug (14) is removable by pressure caused by a dispensing action of the drug delivery device (50).
摘要翻译：提供药物贮存器（10）以与药物输送装置（50）一起使用。药液贮存器（10）被布置成包括药物（13），并且包括用于将药物（13）分配到药物输送装置（50）的环境中的分配孔（15）。药物储存器（10）还包括可变形插塞（14），该插塞（14）可以由药物输送装置（50）的分配动作引起的压力移除。

7. 发明授权

US08830549B2 Holographic dislpay using liquid crystal display device operating with unpolorized light 有权
标题翻译：使用液晶显示装置进行全息打印，使用无色光进行操作
公开(公告)号：US08830549B2
公开(公告)日：2014-09-09
申请号：US12303964
申请日：2007-05-29
申请人： Alok Govil , Lucian Remus Albu
发明人： Alok Govil , Lucian Remus Albu
IPC分类号： G03H1/08 , G03H1/22
CPC分类号： G03H1/2294 , G03H2222/31 , G03H2225/22 , G03H2225/52 , G03H2240/15
摘要： An electroholographic display system (800, 900) for displaying a holographic image, includes a coherent light source (830, 930) producing a coherent, collimated, light beam; a spatial light modulator (SLM) (820, 920) adapted to receive and spatially modulate the coherent, collimated, light beam to produce therefrom a spatially modulated light beam including first portions having a first polarization and second portions having a second polarization orthogonal to the first polarization; and a processor and driver unit (810, 910) adapted to generate hologram data representing a holographic image and to apply appropriate voltages to the pixels of the SLM to cause the SLM to modulate the coherent collimated light beam with the hologram data. The spatially modulated light beam is projected to an image plane to produce the holographic image including the first portions having the first polarization and the second portions having a second polarization orthogonal to the first polarization.
摘要翻译：用于显示全息图像的电子照相显示系统（800,900）包括产生相干，准直光束的相干光源（830,930）; 空间光调制器（SLR），其适于接收和空间调制所述相干平行的光束，从而产生空间调制的光束，所述空间调制光束包括具有第一偏振的第一部分和具有与所述第一极化正交的第二偏振的第二部分第一极化以及适于产生表示全息图像的全息图数据并且向SLM的像素施加适当电压以使SLM利用全息图数据调制相干准直光束的处理器和驱动单元（810,910）。将空间调制的光束投影到图像平面，以产生包括具有第一偏振的第一部分和第二部分具有与第一偏振正交的第二偏振的全息图像。

8. 发明授权

US08765099B2 Magnetic resonance imaging hyperpolarization of liquids or solids by light with orbital angular momentum 失效
标题翻译：磁共振成像通过光与轨道角动量的液体或固体超极化
公开(公告)号：US08765099B2
公开(公告)日：2014-07-01
申请号：US12808385
申请日：2008-12-19
申请人： Daniel R. Elgort , Lucian Remus Albu
发明人： Daniel R. Elgort , Lucian Remus Albu
IPC分类号： A61B5/055
CPC分类号： G02B5/32 , G01N24/08 , G01R33/282 , G01R33/285 , G02B27/0037 , G02B27/4244 , G02B27/425 , G02B27/46
摘要： In magnetic resonance imaging (MRI), selected magnetic dipoles in a subject are aligned with a main magnetic field for later manipulation, and signals received after such manipulations are used to create image representations of the subject. One drawback is that even powerful magnetic fields can only align a very small percentage of dipoles in the region of the field. Electromagnetic radiation endowed with orbital angular momentum (OAM) aligns dipoles along the direction of travel of the radiation, but at a much higher percentage; as high as 100% of the dipoles in the region can be aligned. Resultantly, resonance signals emanating from the region are several orders of magnitude stronger than signals emanated using traditional MRI techniques. All electromagnetic radiation, including visible light can be endowed with OAM and used to hyperpolarize a region of interest.
摘要翻译：在磁共振成像（MRI）中，被检体中选定的磁偶极子与主磁场对准以供后续操作，并且使用这些操作之后接收的信号来产生受试者的图像表示。一个缺点是，甚至强大的磁场只能在场的区域中排列非常小百分比的偶极子。具有轨道角动量（OAM）的电磁辐射沿着辐射的行进方向对准偶极子，但是以高得多的百分比; 该区域中高达100％的偶极子可以对齐。结果，从该地区发出的共振信号比使用传统MRI技术发出的信号强大几个数量级。包括可见光在内的所有电磁辐射都可以被赋予OAM，并用于超极化感兴趣的区域。

9. 发明申请

US20130197440A1 MEDICINE RESERVOIR FOR DRUG DELIVERY DEVICE 有权
标题翻译：药物储存器用于药物递送装置
公开(公告)号：US20130197440A1
公开(公告)日：2013-08-01
申请号：US13390110
申请日：2010-08-09
申请人： Hans Zou , Jeff Shimizu , Lucian Remus Albu
发明人： Hans Zou , Jeff Shimizu , Lucian Remus Albu
IPC分类号： A61M31/00
CPC分类号： A61M31/00 , A61M31/002
摘要： A medicine reservoir (10) is provided for use with a drug delivery device (50). The medicine reservoir (10) is arranged for comprising a drug (13) and comprises a dispensing hole (15) for dispensing the drug (13) into an environment of the drug delivery device (50). The medicine reservoir (10) further comprises a deformable plug (14) which plug (14) is removable by pressure caused by a dispensing action of the drug delivery device (50).
摘要翻译：提供药物贮存器（10）以与药物输送装置（50）一起使用。药液贮存器（10）被布置成包括药物（13），并且包括用于将药物（13）分配到药物输送装置（50）的环境中的分配孔（15）。药物储存器（10）还包括可变形插塞（14），该插塞（14）可以由药物输送装置（50）的分配动作引起的压力移除。

10. 发明申请

US20120086453A1 MRI WITH HYPERPOLARISATION DEVICE USING PHOTONS WITH ORBITAL ANGULAR MOMENTUM 审中-公开
标题翻译：使用光子与椭圆形光子的高次谐波器件进行磁共振成像
公开(公告)号：US20120086453A1
公开(公告)日：2012-04-12
申请号：US13378193
申请日：2010-06-09
申请人： Lucian Remus Albu , Daniel R. Elgort
发明人： Lucian Remus Albu , Daniel R. Elgort
IPC分类号： G01R33/34
CPC分类号： G01R33/62 , G01N24/006 , G01R33/282
摘要： A photonic-based hyperpolarisation device is disclosed with an electromagnetic source for emitting photonic radiation having a substantial penetration depth for material of the object, in particular of tissue, to be examined. For example, soft or ultra-soft x-rays are applied. Notably, the photonic-based hyperpolarisation device incorporates a magnet to generate a static magnetic field. Alternatively, the photonic-based hyperpolarisation device is incorporated in an magnetic resonance examination system.
摘要翻译：公开了一种基于光子的超极化装置，其具有用于发射光子辐射的电磁源，所述光子辐射具有用于要检查的物体，特别是组织的材料的基本穿透深度。例如，应用软或超软X射线。值得注意的是，基于光子的超极化装置包含磁体以产生静磁场。或者，基于光子的超极化装置并入磁共振检查系统中。

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