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1. 发明授权

US09155744B2 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries 有权
标题翻译：用于再生肌纤维治疗肌肉损伤的药物组合物和方法
公开(公告)号：US09155744B2
公开(公告)日：2015-10-13
申请号：US11722915
申请日：2006-10-27
申请人： Ming Li , Lei Cheng , Hong Wei Liu
发明人： Ming Li , Lei Cheng , Hong Wei Liu
IPC分类号： A61K31/56 , A61K31/704 , C07C62/32
CPC分类号： A61K31/704 , A61K31/192 , A61K31/56 , A61K35/34 , C07C62/32
摘要： A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.
摘要翻译：用于再生心肌细胞治疗或修复由缺血性疾病引起的心肌损伤或损伤的药物组合物和方法。药物组合物含有具有式（I）的骨架结构的活性成分化合物。活性成分化合物能够（a）增加肌原性前体细胞的活力，使所述前体细胞能够通过绝对缺血期生存; （b）在所述受伤的肌肉位于的所述心脏区域中重建损伤的血液供应网络; 和（c）提高所述前体细胞向下心肌的心肌分化效率，所述步骤同时进行或以任何特定的顺序进行。

2. 发明授权

US07555301B2 Method and apparatus for coverage and throughput enhancement in a wireless communication system 失效
标题翻译：无线通信系统中覆盖和吞吐量增强的方法和装置
公开(公告)号：US07555301B2
公开(公告)日：2009-06-30
申请号：US11507827
申请日：2006-08-21
申请人： Efstratios Skafidas , Ben Jones , John (Jack) Morton , Mike Gibson , Neil Patrick Kelly , Nestor Fesas , Mark William Benson , Richard John Rusnak , James Glick , Duy Khuong Do , Douglas A. Mammosser , Lei Cheng , Kevin Sean Broe , Natarajan Ekambaram
发明人： Efstratios Skafidas , Ben Jones , John (Jack) Morton , Mike Gibson , Neil Patrick Kelly , Nestor Fesas , Mark William Benson , Richard John Rusnak , James Glick , Duy Khuong Do , Douglas A. Mammosser , Lei Cheng , Kevin Sean Broe , Natarajan Ekambaram
IPC分类号： H04Q7/20
CPC分类号： H04W16/28 , H01Q1/246 , H01Q25/002 , H04B7/0491 , H04W16/14 , H04W16/24 , H04W24/00 , H04W72/04 , H04W72/082
摘要： A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment. In one embodiment, a mode of operation is selected from a plurality of modes of operation, enabling a wireless communications transmitter to be dynamically configured to reach a wireless communications devices at a greater distance from the transmitter without increased interference between communications channels (“range mode”) or to provide wireless communications to a greater number of wireless communications devices within a relatively closer distance to the wireless transmitter (“capacity mode”) or to provide wireless communications using a single channel to provide wireless communications at a relatively greatest distance from the transmitter (“super range mode”).
摘要翻译：多址无线通信架构提供与位于被称为“扇区”的通信设备周围的空间区域的不同部分中的无线设备的选择性同时通信。在一个实施例中，用于增加无线通信环境中的吞吐量和覆盖范围中的一个或多个的信道分配技术。在一个实施例中，从多种操作模式中选择操作模式，使得无线通信发射机能够被动态配置为在距离发射机更远的距离处到达无线通信设备，而不增加通信信道之间的干扰（“范围模式 “）或者在与无线发射机相对较近的距离内向更多数量的无线通信设备提供无线通信（”容量模式“），或者使用单个信道来提供无线通信，以在距离无线发射机相对最远的距离处提供无线通信发射机（“超级范围模式”）。

3. 发明申请

US20090022827A1 AGENT AND METHOD FOR ELIMINATING MALIGNANCE OF CANCER CELLS WITHOUT HARMFUL EFFECT TO NORMAL CELLS 审中-公开
标题翻译：用于消除癌细胞恶性病变的代理和方法，对正常细胞没有有害的作用
公开(公告)号：US20090022827A1
公开(公告)日：2009-01-22
申请号：US12176441
申请日：2008-07-21
申请人： Ming Li , Lei Cheng
发明人： Ming Li , Lei Cheng
IPC分类号： A61K36/73 , A61P35/04
CPC分类号： A61K36/73
摘要： A pharmaceutical composition including an extract from Geum japonicum and a method of treating cancer using the extract. In vitro and in vivo experimental data demonstrated that the extract can induce selectively apoptosis of cancer cells and kill the cancer cells without affect normal cells.
摘要翻译：一种药用组合物，其特征在于，包括天麻提取物和使用所述提取物治疗癌症的方法。体外和体内实验数据表明，提取物可以诱导癌细胞的选择性凋亡，并杀死癌细胞而不影响正常细胞。

4. 发明授权

US06233595B1 Fast multiplication of floating point values and integer powers of two 失效
标题翻译：浮点数和二进制的整数幂的快速乘法
公开(公告)号：US06233595B1
公开(公告)日：2001-05-15
申请号：US09075074
申请日：1998-05-08
申请人： Lei Cheng , Frank J. Gorishek, IV , Yi Liu
发明人： Lei Cheng , Frank J. Gorishek, IV , Yi Liu
IPC分类号： G06F9302
CPC分类号： G06F7/4876 , G06F9/30014
摘要： A method for performing fast multiplication in a microprocessor is disclosed. The method comprises detecting multiplication operations that have a floating point operand and an integer operand, wherein the integer operand is an integer power of two. Once detected, a multiplication operation meeting these criteria may be executed by using an integer adder to sum the integer power and the floating point operand's exponent to from a product exponent. The bias of the integer operand's exponent may also be subtracted. A product mantissa is simply copied from the floating point operand's mantissa. The floating point operand's sign bit may be inverted to form the product's sign bit if the integer operand is negative. Advantageously, the product is generated using integer addition which is faster than floating point multiplication. The method may be implemented in hardware or software.
摘要翻译：公开了一种在微处理器中执行快速乘法的方法。该方法包括检测具有浮点操作数和整数操作数的乘法运算，其中整数操作数是2的整数幂。一旦被检测到，可以通过使用整数加法器来执行满足这些标准的乘法运算，以从乘积指数将整数幂和浮点运算数的指数相加。也可以减去整数操作数的指数的偏差。产品尾数简单地从浮点运算符的尾数复制出来。如果整数操作数为负，则浮点运算符的符号位可能会反转，以形成乘积符号位。有利地，使用比浮点乘法更快的整数加法来产生乘积。该方法可以在硬件或软件中实现。

5. 发明申请

US20120252744A1 Pharmaceutical Composition and Method for Neoangiogenesis/Revascularization Useful in Treating Ischemic Heart Disease 审中-公开
标题翻译：用于治疗缺血性心脏病的新血管生成/血运重建的药物组合物和方法
公开(公告)号：US20120252744A1
公开(公告)日：2012-10-04
申请号：US13517600
申请日：2012-06-14
申请人： Ming Li , Lei Cheng , Hong Wei Liu
发明人： Ming Li , Lei Cheng , Hong Wei Liu
IPC分类号： A61K31/7034 , A61P9/10
CPC分类号： A61K31/7034 , A61K9/0019 , A61K9/0053
摘要： A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (I).
摘要翻译：一种药物组合物和通过生长新的血管来治疗缺血性心脏病的方法，所述新血管向整个梗塞区域的梗死心脏组织供氧和营养，并用于预防缺血事件中的心肌细胞凋亡。药物组合物含有具有式（I）的骨架结构的活性成分化合物。

6. 发明申请

US20120177759A1 COMPOSITIONS AND METHODS FOR INCREASING LIFESPAN AND HEALTH SPAN 有权
标题翻译：组合物和增加生活和健康的范围的方法
公开(公告)号：US20120177759A1
公开(公告)日：2012-07-12
申请号：US13377501
申请日：2010-06-11
申请人： Ming Li , Lei Cheng
发明人： Ming Li , Lei Cheng
IPC分类号： A61K36/73 , A61P27/02 , A61P17/02 , A61P3/10
CPC分类号： A61K36/00 , A61K31/56 , A61K31/565 , A61K31/7028 , A61K31/7032 , A61K31/7034 , A61K36/23 , A61K36/73 , A61K2300/00 , Y02A50/411
摘要： Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum and methods for increasing longevity and survival potency or for preventing or treating various medical conditions, including diabetes, inflammation, wound healing, bed sores, and ocular disorders. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments
摘要翻译：本文公开了植物天麻的化合物，提取物和活性级分以及用于增加寿命和存活效力或用于预防或治疗各种医学病症（包括糖尿病，炎症，伤口愈合，褥疮和眼部疾病）的方法。本文提供的化合物可以配制成在所公开的方法中有用的药物组合物和药物。还提供了化合物和提取物在制备药物制剂和药物中的用途

7. 发明申请

US20080124388A1 Pharmaceutical Composition And Method For Neoangiogenesis/Revascularization Useful In Treating Ischemic Heart Diseases 审中-公开
标题翻译：用于治疗缺血性心脏病的新血管生成/血运重建的药物组合物和方法
公开(公告)号：US20080124388A1
公开(公告)日：2008-05-29
申请号：US11722911
申请日：2006-10-27
申请人： Ming Li , Lei Cheng , Hong Wei Liu
发明人： Ming Li , Lei Cheng , Hong Wei Liu
IPC分类号： A61K31/7024 , A61K9/48 , A61K9/20
CPC分类号： A61K31/704 , A61K31/192 , A61K31/56 , A61K35/34 , C07C62/32
摘要： A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (I).
摘要翻译：一种药物组合物和通过生长新的血管来治疗缺血性心脏病的方法，所述新血管向整个梗塞区域的梗死心脏组织供氧和营养，并用于预防缺血事件中的心肌细胞凋亡。药物组合物含有具有式（I）的骨架结构的活性成分化合物。

8. 发明申请

US20060281412A1 Method and apparatus for coverage and throughput enhancement in a wireless communication system 失效
公开(公告)号：US20060281412A1
公开(公告)日：2006-12-14
申请号：US11507827
申请日：2006-08-21
申请人： Efstratios Skafidas , Ben Jones , John Morton , Mike Gibson , Neil Kelly , Nestor Fesas , Mark Benson , Richard Rusnak , James Glick , Duy Do , Douglas Mammoser , Lei Cheng , Kevin Broe , Natarajan Ekambaram
发明人： Efstratios Skafidas , Ben Jones , John Morton , Mike Gibson , Neil Kelly , Nestor Fesas , Mark Benson , Richard Rusnak , James Glick , Duy Do , Douglas Mammoser , Lei Cheng , Kevin Broe , Natarajan Ekambaram
IPC分类号： H04B1/00
CPC分类号： H04W16/28 , H01Q1/246 , H01Q25/002 , H04B7/0491 , H04W16/14 , H04W16/24 , H04W24/00 , H04W72/04 , H04W72/082
摘要： A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment. In one embodiment, a mode of operation is selected from a plurality of modes of operation, enabling a wireless communications transmitter to be dynamically configured to reach a wireless communications devices at a greater distance from the transmitter without increased interference between communications channels (“range mode”) or to provide wireless communications to a greater number of wireless communications devices within a relatively closer distance to the wireless transmitter (“capacity mode”) or to provide wireless communications using a single channel to provide wireless communications at a relatively greatest distance from the transmitter (“super range mode”).

9. 发明授权

US07136655B2 Method and apparatus for coverage and throughput enhancement in a wireless communication system 无效
公开(公告)号：US07136655B2
公开(公告)日：2006-11-14
申请号：US10870199
申请日：2004-06-16
申请人： Efstratios Skafidas , Ben Jones , John “Jack” Morton , Mike Gibson , Neil Patrick Kelly , Nestor Fesas , Mark William Benson , Richard John Rusnak , James Glick , Duy Khuong Do , Douglas A. Mammoser , Lei Cheng , Kevin Sean Broe , Natarajan Ekambaram
发明人： Efstratios Skafidas , Ben Jones , John “Jack” Morton , Mike Gibson , Neil Patrick Kelly , Nestor Fesas , Mark William Benson , Richard John Rusnak , James Glick , Duy Khuong Do , Douglas A. Mammoser , Lei Cheng , Kevin Sean Broe , Natarajan Ekambaram
IPC分类号： H04Q7/20
CPC分类号： H04W16/28 , H01Q1/246 , H01Q25/002 , H04B7/0491 , H04W16/14 , H04W16/24 , H04W24/00 , H04W72/04 , H04W72/082
摘要： A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment. In one embodiment, a mode of operation is selected from a plurality of modes of operation, enabling a wireless communications transmitter to be dynamically configured to reach a wireless communications devices at a greater distance from the transmitter without increased interference between communications channels (“range mode”) or to provide wireless communications to a greater number of wireless communications devices within a relatively closer distance to the wireless transmitter (“capacity mode”) or to provide wireless communications using a single channel to provide wireless communications at a relatively greatest distance from the transmitter (“super range mode”).

10. 发明授权

US5974510A Method for testing the non-cacheable region functioning of a cache memory controller 失效
标题翻译：用于测试缓存存储器控制器的非高速缓存区域功能的方法
公开(公告)号：US5974510A
公开(公告)日：1999-10-26
申请号：US962361
申请日：1997-10-31
申请人： Lei Cheng , Thomas F. Eckert , Michael T. Wisor
发明人： Lei Cheng , Thomas F. Eckert , Michael T. Wisor
IPC分类号： G06F12/08 , G11C29/12
CPC分类号： G06F12/0888 , G11C29/12
摘要： A method for testing the functioning of a non-cacheable region within a cache having a cache controller programmed with a write-back write policy and a non-cacheable region included in an image memory region corresponding to a physical memory region. A first data pattern is written to the cache tagged at a first addressable location of a cacheable region in the physical memory region. A second data pattern is written to the cache tagged at a second addressable location in the image memory region contained within both the non-cacheable region and the cacheable region and corresponding to the first addressable location. The data stored in the cache and tagged at the first addressable location and corresponding to the non-cacheable region only of the second addressable location is read to determine whether the first data pattern remains in the cache thereby indicating that the non-cacheable region is functioning correctly. The data stored and tagged at a third addressable location in the physical memory region and corresponding to the cacheable region only of the second addressable location in the image memory region is read to determine whether the second data pattern remains in the cache tagged at the third addressable location thereby indicating that the non-cacheable region is functioning correctly and that the memory size of the non-cacheable region is correct.
摘要翻译：一种用于测试具有由写回写入策略编程的高速缓存控制器和包含在对应于物理存储器区域的图像存储器区域中的不可缓存区域的高速缓存内的不可缓存区域的功能的方法。将第一数据模式写入物理存储器区域中的可缓存区域的第一可寻址位置处标记的高速缓存。将第二数据模式写入到包含在不可缓存区域和可高速缓存区域内并对应于第一可寻址位置的图像存储器区域中的第二可寻址位置处标记的高速缓存。读取存储在高速缓存中并且在第一可寻址位置处标记并且仅对应于第二可寻址位置的不可缓存区域的数据，以确定第一数据模式是否保留在高速缓存中，从而指示不可缓存区域正在运行正确的在物理存储器区域中存储和标记在第三可寻址位置并且仅对应于图像存储器区域中的第二可寻址位置的可高速缓存区域的数据被读取以确定第二数据模式是否保留在第三可寻址的标记的高速缓存位置，从而指示不可缓存区域正常工作，并且非可缓存区域的存储器大小是正确的。

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