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1. 发明申请

WO2020264257A1 ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2020264257A1
公开(公告)日：2020-12-30
申请号：PCT/US2020/039759
申请日：2020-06-26
申请人： LIVING PROOF, INC.
发明人： KANG, Soo-Young , JI, Zhaoxia , VILLANUEVA, Dinara, A. , ABEYRATHNA, Nawodi
IPC分类号： A61K8/36 , A61K8/362 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/44 , A61K8/46 , A61Q5/06 , A61Q5/10
摘要： Disclosed are methods for coloring hair, comprising applying a mixture comprising one or more hair dyes and an additive as a pre-treatment, as a simultaneous treatment, as a post-treatment, or a combination thereof.

2. 发明申请

WO2019099819A1 COVALENT TREATMENT FOR KERATIN-CONTAINING MATERIALS 审中-公开
公开(公告)号：WO2019099819A1
公开(公告)日：2019-05-23
申请号：PCT/US2018/061505
申请日：2018-11-16
申请人： LIVING PROOF, INC.
发明人： KANG, Soo-Young , JI, Zhaoxia , JOHNSON, Sara, A. , VILLANUEVA, Dinara, A. , JOHNSON, Jeremiah, A. , QIN, Xu
IPC分类号： A61K8/65 , A61K8/81 , A61K38/17 , C08H1/06 , C08L101/02 , D06M14/06
CPC分类号： A61K8/91 , A61K8/365 , A61K8/447 , A61K8/498 , A61K8/55 , A61K8/8105 , A61K8/8135 , A61K8/8152 , A61K8/8158 , A61K2800/10 , A61K2800/54 , A61K2800/95 , A61Q1/10 , A61Q3/00 , A61Q5/002
摘要： Disclosed are methods of grafting monomeric and polymeric materials on keratin- containing material to provide a covalent coating on keratin-containing material. A mixture comprising a reducing agent is applied to the keratin-containing material sample. The keratin- containing material sample then comprises a plurality of free thiol groups. A monomer is applied to the keratin-containing material sample. The free thiol groups react with the monomer to form a plurality of covalent bonds between the free thiol groups and the monomers. The reducing agent and the monomer can be applied separately, semi- simultaneously, or simultaneously. The disclosed methods can be carried out with or without catalyst. The disclosed methods can be carried out with or without an additive.

3. 发明申请

WO2008134712A3 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE 审中-公开
标题翻译：在皮肤护理中使用基质金属蛋白酶抑制剂
公开(公告)号：WO2008134712A3
公开(公告)日：2012-08-02
申请号：PCT/US2008061992
申请日：2008-04-30
申请人： LIVING PROOF INC , YU BETTY , NASHAT AMIR , ANDERSON DANIEL GRIFFITH , PUERTA DAVID THOMAS , ADAMS BENJAMIN , CLARK SCOTT , KIM YUSHAN , SPENGLER ERIC GEORGE , MCLAUGHLIN RONALD P , BEDFORD SUSAN EILIDH , LI ZHI
发明人： YU BETTY , NASHAT AMIR , ANDERSON DANIEL GRIFFITH , PUERTA DAVID THOMAS , ADAMS BENJAMIN , CLARK SCOTT , KIM YUSHAN , SPENGLER ERIC GEORGE , MCLAUGHLIN RONALD P , BEDFORD SUSAN EILIDH , LI ZHI
IPC分类号： A61K8/49 , A61Q19/08
CPC分类号： A61K8/062 , A61K8/0212 , A61K8/0229 , A61K8/064 , A61K8/14 , A61K8/498 , A61K2800/31 , A61K2800/782 , A61Q17/04 , A61Q19/00 , A61Q19/005 , A61Q19/08
摘要： The application of matrix metalloproteinase (MMP) inhibitors to the skin inhibits the degradation of proteins found in the skin including collagen, elastin, and other basement membrane and extracellular matrix protein. MMP inhibitors may be used in both cosmetic compositions and pharmaceutical compositions for application to skin. MMP inhibitors are formulated with a cosmetically suitable vehicle or pharmaceutically acceptable excipient for application to the skin as creams, lotions, ointments, solutions, face masks, etc. As cosmetics, the inventive MMP inhibitor compositions are applied to the skin to prevent or reduce the appearance of wrinkles, pigmentation changes, loss of elasticity, or other effects associated with aging or sun damage. As pharmaceuticals, the inventive MMP inhibitor compositions may also be applied to the skin to treat or prevent a skin disease (e.g., proliferative disease, inflammatory disease).
摘要翻译：基质金属蛋白酶（MMP）抑制剂对皮肤的应用抑制皮肤中发现的蛋白质的降解，包括胶原蛋白，弹性蛋白，以及其他基底膜和细胞外基质蛋白质。 MMP抑制剂可用于化妆品组合物和用于皮肤应用的药物组合物中。 MMP抑制剂与美容上合适的载体或药学上可接受的赋形剂一起配制，用于作为乳膏，洗剂，软膏，溶液，面罩等应用于皮肤。作为化妆品，将本发明的MMP抑制剂组合物施用于皮肤以预防或减少皱纹的出现，色素沉着变化，丧失弹性或与老化或太阳损伤有关的其他影响。作为药物，本发明的MMP抑制剂组合物也可以施用于皮肤以治疗或预防皮肤疾病（例如增殖性疾病，炎性疾病）。

4. 发明申请

WO2019099966A1 PROPERTIES FOR ACHIEVING LONG-LASTING COSMETIC PERFORMANCE 审中-公开
公开(公告)号：WO2019099966A1
公开(公告)日：2019-05-23
申请号：PCT/US2018/061718
申请日：2018-11-19
申请人： LIVING PROOF, INC.
发明人： KANG, Soo-Young , JI, Zhaoxia , TSENG, Ling-Fang , VILLANUEVA, Dinara, A. , JOHNSON, Sara, A.
IPC分类号： A61Q5/06 , A61K8/73 , A61K8/81
摘要： Provided herein are long lasting hair styling compositions and markers for selecting the same. The compositions comprise one or more non-polyurethane or non-polyurethane urea based polymers having a Young's modulus above 150 MPa, an elongation at break of from about 15% to about 300% and a moisture uptake of less than 10%. Preferred compositions comprise combinations of acrylates copolymer with modified corn starch, acrylates/octylacrylamide copolymer, polyvinylcaprolactam, octylacrylamide/acrylates/butylaminoethyl methacrylate copolymer, polyquaternium-69 or vinyl pyrrolidone/ methacrylamide/vinyl imidazole copolymer.

5. 发明申请

WO2017155906A8 LONG LASTING COSMETIC COMPOSITIONS 审中-公开
公开(公告)号：WO2017155906A8
公开(公告)日：2017-09-14
申请号：PCT/US2017/021025
申请日：2017-03-07
申请人： LIVING PROOF, INC.
发明人： KANG, Soo-Young , TURNER, Sara, A. , TSENG, Ling-Fang , JI, Zhaoxia , SPENGLER, Eric, G.
IPC分类号： C08G18/44 , C08G18/12 , C08G18/42 , C08G18/08 , C08G18/28 , C08G18/38 , A61Q5/06 , A61K8/87 , C08G18/75 , C08G18/10
摘要： Provided herein long lasting cosmetic compositions and markers for selecting the same.

6. 发明申请

WO2015066266A1 SCALE AND ASSOCIATED METRIC FOR TREATMENT OF FACIAL WRINKLES AND RELATED CONDITIONS 审中-公开
标题翻译：用于治疗面部皱纹的比例和相关的公制及相关条件
公开(公告)号：WO2015066266A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063048
申请日：2014-10-30
申请人： LIVING PROOF, INC.
发明人： YU, Betty , BIESMAN, Brian
IPC分类号： A61B5/00
CPC分类号： A61B5/442 , A61B5/4878 , A61K8/0208 , A61K2800/805 , A61Q19/08 , G06F19/00 , G16H50/20
摘要： This invention provides assessment scale devices and methods for assessing the severity of wrinkles and facial swelling and puffiness. Wrinkle and facial swelling/puffiness assessment using the devices, methods, and assessment scales of the invention can be performed in a clinical setting for the purpose of simply characterizing a wrinkle or facial swelling/puffiness, or as part of a treatment plan or course that varies according to the severity of the wrinkle or facial swelling/puffiness. Thus, this invention also provides methods of reducing the appearance of wrinkles and/or facial puffiness, and kits comprising for evaluating and treating wrinkles and/or facial puffiness. Additionally, the present disclosure relates to a devices, methods, and assessment scales for managing expectations of the given treatment plan or course for human facial wrinkles and facial puffiness.
摘要翻译：本发明提供了用于评估皱纹和面部肿胀和浮肿的严重程度的评估尺度装置和方法。为了简单地表征皱纹或面部肿胀/浮肿的目的，或者作为治疗计划或疗程的一部分，可以在临床设置中使用本发明的装置，方法和评估量表进行皱纹和面部肿胀/浮肿评估根据皱纹或面部肿胀/浮肿的严重程度而变化。因此，本发明还提供了减少皱纹和/或面部浮肿的外观的方法以及包含用于评估和治疗皱纹和/或面部浮肿的试剂盒。此外，本公开涉及用于管理针对人类面部皱纹和面部浮肿的给定治疗计划或疗程的期望的装置，方法和评估尺度。

7. 发明申请

WO2013158844A3 COLOR CORRECTING COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开
标题翻译：颜色校正组合物及其使用方法
公开(公告)号：WO2013158844A3
公开(公告)日：2014-12-24
申请号：PCT/US2013037116
申请日：2013-04-18
申请人： LIVING PROOF INC
发明人： LOMAKIN JOSEPH , KANG SOO-YOUNG , YU BETTY , PILKENTON MORGAN
IPC分类号： A61K8/25 , A61K8/58 , A61K8/895 , A61Q1/02 , A61Q17/04
CPC分类号： A61K8/895 , A61K8/25 , A61K8/585 , A61K2800/884 , A61K2800/95 , A61Q1/02 , A61Q17/04
摘要： Compositions and methods of for changing the color of skin or body described, involving in-situ crosslinking on the skin.
摘要翻译：用于改变皮肤或身体颜色的组合物和方法，涉及皮肤上的原位交联。

8. 发明申请

WO2012030993A2 SKIN COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开
标题翻译：皮肤组合物及其使用方法
公开(公告)号：WO2012030993A2
公开(公告)日：2012-03-08
申请号：PCT/US2011/050016
申请日：2011-08-31
申请人： LIVING PROOF, INC. , YU, Betty , LOMAKIN, Joseph , KANG, Soo-Young , ADAMS, Benjamin, W.
发明人： YU, Betty , LOMAKIN, Joseph , KANG, Soo-Young , ADAMS, Benjamin, W.
IPC分类号： A61K31/74 , A61K31/795 , A61K8/89 , A61P17/02 , A61Q19/00
CPC分类号： A61K31/765 , A61K8/0204 , A61K8/19 , A61K8/25 , A61K8/29 , A61K8/345 , A61K8/585 , A61K8/891 , A61K8/894 , A61K8/895 , A61K2800/412 , A61K2800/43 , A61K2800/58 , A61K2800/5922 , A61K2800/884 , A61K2800/95 , A61L26/0019 , A61L26/0095 , A61Q1/02 , A61Q1/14 , A61Q19/00 , A61Q19/06 , A61Q19/08 , C08L83/04
摘要： Provided are therapeutic formulations and methods of use thereof.
摘要翻译：提供治疗剂型及其使用方法。

9. 发明申请

WO2009055489A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR 审中-公开
标题翻译：头发护理组合物和治疗头发的方法
公开(公告)号：WO2009055489A1
公开(公告)日：2009-04-30
申请号：PCT/US2008/080819
申请日：2008-10-22
申请人： LIVING PROOF, INC. , ANDERSON, Daniel, Griffith , NASHAT, Amir , DEROSA, Mitchell, John , PUERTA, David, Thomas , MCLAUGHLIN, Ronald, P. , AKCASU, Bryan, Scott , WILLIAMS, Susan, Alice , RAMIREZ, Richard, Matthew
发明人： ANDERSON, Daniel, Griffith , NASHAT, Amir , DEROSA, Mitchell, John , PUERTA, David, Thomas , MCLAUGHLIN, Ronald, P. , AKCASU, Bryan, Scott , WILLIAMS, Susan, Alice , RAMIREZ, Richard, Matthew
IPC分类号： A61K8/00 , A61K8/18 , A61Q5/00
CPC分类号： A61K8/37 , A61K8/8152 , A61Q5/06 , A61Q5/12 , A61Q9/02
摘要： The present invention provides compositions, kits and methods for treating scalp hair. The compositions include fluorinated (but not perfluorinated), non- polymeric compounds in a suitable excipient to provide beneficial effects on hair.
摘要翻译：本发明提供用于治疗头皮头发的组合物，试剂盒和方法。组合物包括氟化（但不是全氟化的）非合适赋形剂中的非聚合物，以提供对头发的有益作用。

10. 发明申请

WO2023034283A1 METHODS FOR STRENGTHENING AND REPAIRING HAIR 审中-公开
公开(公告)号：WO2023034283A1
公开(公告)日：2023-03-09
申请号：PCT/US2022/042012
申请日：2022-08-30
申请人： LIVING PROOF, INC.
发明人： JI, Zhaoxia , ABEYRATHNA, Nawodi , BRYANT, Harold , MCLAUGHLIN, Ronald P.
IPC分类号： A61K8/55 , A61Q5/00
摘要： Provided are methods of strengthening or repairing hair comprising applying phytic acid (PA), alone or in combination with glucono-delta- lactone (GL), to the hair and methods of protecting hair from heat or chemical treatments comprising applying phytic acid to the hair. The hair may have been bleached, reduced or colour treated prior to application of phytic acid or phytic acid and glucono-delta-lactone and may be heated after the application. Improvements in denaturization temperature, Young's modulus, break stress, surface hydrophobicity, water contact angle and protein loss may be observed.

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