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1. 发明授权

US06461353B1 Orthopedic apparatus for controlled contraction of collagen tissue 失效
标题翻译：骨科装置可控制收缩胶原组织
公开(公告)号：US06461353B1
公开(公告)日：2002-10-08
申请号：US08888359
申请日：1997-07-03
申请人： James A. Baker, Jr. , Edward J. Gough
发明人： James A. Baker, Jr. , Edward J. Gough
IPC分类号： A61B1814
CPC分类号： A61B18/1487 , A61B18/18 , A61B18/1815 , A61B2017/003
摘要： An orthopedic apparatus, for effecting a change in ligaments, joint capsules and connective tissue through the controlled contraction of collagen fibers, includes a trocar. The trocar has a trocar elongated body with a trocar longitudinal axis, a trocar distal end that is laterally deflectable relative to the trocar longitudinal axis, and a trocar proximal end. An electrode is positioned at the trocar distal end. The electrode delivers substantially uniform energy across an energy delivery surface of the electrode. The energy delivery surface is positioned next to an area of collagen fibers to cause a controlled amount of contraction of the collagen fibers while minimizing dissociation and breakdown of the collagen fibers. A handle is positioned at the proximal end of the trocar. The handle includes an actuating member and a locking member. The actuating member has a resting position and one or more activation positions that cause the trocar distal end to become laterally deflected to a desired position of deflection. The locking member has a resting position and a locking position that locks the deflected trocar distal end in place. Further, the locking member is releasable from the locking position to the resting position or to one that is intermediate between the two in order to modify the activation position of the actuating member and change the deflection of the trocar distal end. The distal end's deflection can be readily adjusted and can return to a non-deflected position. The handle can be held in one hand, and the actuating and locking members each operable by a thumb and a finger of the hand.
摘要翻译：用于通过胶原纤维的受控收缩实现韧带，关节胶囊和结缔组织改变的矫形装置包括套管针。套针针具有套管针细长体，其具有套针针纵向轴线，相对于套管针纵向轴线可横向偏转的套针针远端和套管针近端。电极位于套管针远端。电极在电极的能量输送表面上提供基本均匀的能量。能量输送表面位于胶原纤维的一个区域旁边，以引起胶原纤维受控量的收缩，同时使胶原纤维的解离和分解最小化。手柄位于套管针的近端。手柄包括致动构件和锁定构件。致动构件具有静止位置和一个或多个激活位置，其使套管针远端横向偏转到期望的偏转位置。锁定构件具有静止位置和将偏转的套管针远端锁定就位的锁定位置。此外，锁定构件可以从锁定位置释放到静止位置，或者释放到位于两者之间的位置，以便改变致动构件的启动位置并改变套管针远端的偏转。远端的偏转可以容易地调节并且可以返回到非偏转位置。手柄可以一只手握住，并且致动和锁定构件各自由手指的拇指和手指操作。

2. 发明授权

US5807309A Transurethral needle ablation device and method for the treatment of the prostate 失效
标题翻译：经尿道针消融装置及治疗前列腺的方法
公开(公告)号：US5807309A
公开(公告)日：1998-09-15
申请号：US790094
申请日：1997-01-29
申请人： Ingemar H. Lundquist , Stuart D. Edwards , James A. Baker, Jr. , Christopher S. Jones , Phillip R. Sommer , Kee S. Lee
发明人： Ingemar H. Lundquist , Stuart D. Edwards , James A. Baker, Jr. , Christopher S. Jones , Phillip R. Sommer , Kee S. Lee
IPC分类号： A61N5/02 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M20060101 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/20
CPC分类号： A61B18/00 , A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61M3/0279 , A61N5/04
摘要： A transurethral needle ablation device for use with the human hand for radio frequency ablation of a target volume in the tissue of a prostate of a human male having a bladder with a base and a penis with a urethra therein formed by a urethral wall extending into the base of the bladder along a longitudinal axis with the tissue of the prostate surrounding the urethra near the base of the bladder. The device comprises a bridge having proximal and distal extremities and having a passage therein extending from the proximal extremity to the distal extremity. A sheath having proximal and distal extremities is secured to the bridge and has a passageway therein in communication with the passage in the bridge. The sheath is sized so that it can enter the urethra and has a length so that when its distal extremity is in the vicinity of the prostate, the proximal extremity is outside the urethra. A disposable needle assembly having proximal and distal extremities is removably mounted in the passage in the bridge and extends through the passageway in the sheath. The needle assembly includes at least one needle electrode and an insulating sleeve coaxially disposed on the needle electrode. The proximal extremity of the needle assembly is caused to be moved sideways at an angle with respect to the longitudinal axis to face the urethral wall. A mechanism is carried by the proximal extremity of the needle assembly and the bridge for causing advancement of the needle electrode and the insulation sleeve thereon through the urethral wall and into the target volume in the tissue of the prostate with a portion of the electrode being free of the insulation but with the insulation extending through the urethral wall.
摘要翻译：一种用于人手的经尿道针消融装置，用于射线消融人体前列腺的前列腺的组织中的目标体积，所述人的男性具有膀胱与基部和阴茎，其中尿道由尿道壁形成，所述尿道壁延伸到膀胱的基部沿着纵向轴线，邻近膀胱底部的尿道周围的前列腺组织。该装置包括具有近端和远端的桥，并具有从近端至远端延伸的通道。具有近端和远端的护套固定到桥上，并且在其中具有与桥中的通道连通的通道。护套的尺寸使得其可以进入尿道并且具有长度，使得当其远端位于前列腺附近时，近端位于尿道外。具有近端和远端的一次性针组件可移除地安装在桥中的通道中并且延伸穿过护套中的通道。针组件包括至少一个针电极和同轴地设置在针电极上的绝缘套管。针组件的近端被相对于纵向轴线以一定角度侧向移动以面向尿道壁。针组件和桥的近端被携带机构，用于使针电极和绝缘套筒在其上通过尿道壁进入并进入前列腺组织中的目标体积，其中一部分电极是自由的的绝缘体，但绝缘体延伸穿过尿道壁。

3. 发明授权

US5762626A Transurethral needle ablation device with cystoscope and method for treatment of the prostate 失效
公开(公告)号：US5762626A
公开(公告)日：1998-06-09
申请号：US701887
申请日：1996-08-23
申请人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
发明人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
IPC分类号： A61N5/02 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M20060101 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B18/00 , A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61M3/0279 , A61N5/04
摘要： A transurethral needle ablation device for the treatment of the prostate of a human male using radio frequency energy wall comprising a sheath having a lumen extending therethrough. A guide tube assembly is slidably mounted in the lumen in the sheath and having a lumen extending therethrough. A needle electrode is slidably mounted in the lumen in the guide tube assembly. An insulating sheath is disposed about the needle electrode so that the distal extremity of the needle electrode is exposed. A handle adapted to be gripped by the human hand is mounted on the proximal extremity of the sheath. Levers are carried by the handle for causing bending of the distal extremity of the guide tube assembly at an angle with respect to its longitudinal axis whereby the lumen in the guide tube assembly can be directed so that it faces the urethral wall. A control is carried by the handle and coupled to the needle electrode and the insulating sleeve for advancing and retracting the needle electrode with respect to the guide tube assembly whereby when the sheath is positioned in the urethra with its distal extremity in the vicinity of the prostate, the needle electrode can be advanced through the urethral wall and into the tissue of the prostate to permit the application of radio frequency energy to the tissue of the prostate surrounding the needle electrode to form a lesion in the prostate.

4. 发明授权

US5667488A Transurethral needle ablation device and method for the treatment of the prostate 失效
标题翻译：经尿道针消融装置及治疗前列腺的方法
公开(公告)号：US5667488A
公开(公告)日：1997-09-16
申请号：US377645
申请日：1995-01-25
申请人： Ingemar H. Lundquist , Stuart D. Edwards , James A. Baker, Jr. , Christopher S. Jones , Phillip R. Sommer , Kee S. Lee
发明人： Ingemar H. Lundquist , Stuart D. Edwards , James A. Baker, Jr. , Christopher S. Jones , Phillip R. Sommer , Kee S. Lee
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M20060101 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61B17/39
CPC分类号： A61B18/00 , A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61M25/0136 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M3/0279 , A61N5/04
摘要： A transurethral needle ablation device for use with the human hand for radio frequency ablation of a target volume in the tissue of a prostate of a human male having a bladder with a base and a penis with a urethra therein formed by a urethral wall extending into the base of the bladder along a longitudinal axis with the tissue of the prostate surrounding the urethra near the base of the bladder. The device comprises a bridge having proximal and distal extremities and having a passage therein extending from the proximal extremity to the distal extremity. A sheath having proximal and distal extremities is secured to the bridge and has a passageway therein in communication with the passage in the bridge. The sheath is sized so that it can enter the urethra and has a length so that when its distal extremity is in the vicinity of the prostate, the proximal extremity is outside the urethra. A disposable needle assembly having proximal and distal extremities is removably mounted in the passage in the bridge and extends through the passageway in the sheath. The needle assembly includes at least one needle electrode and an insulating sleeve coaxially disposed on the needle electrode. The proximal extremity of the needle assembly is caused to be moved sideways at an angle with respect to the longitudinal axis to face the urethral wall. A mechanism is carried by the proximal extremity of the needle assembly and the bridge for causing advancement of the needle electrode and the insulation sleeve thereon through the urethral wall and into the target volume in the tissue of the prostate with a portion of the electrode being free of the insulation but with the insulation extending through the urethral wall.
摘要翻译：一种用于人手的经尿道针消融装置，用于射线消融人体前列腺的前列腺的组织中的目标体积，所述人的男性具有膀胱与基部和阴茎，其中尿道由尿道壁形成，所述尿道壁延伸到膀胱的基部沿着纵向轴线，邻近膀胱底部的尿道周围的前列腺组织。该装置包括具有近端和远端的桥，并具有从近端至远端延伸的通道。具有近端和远端的护套固定到桥上，并且在其中具有与桥中的通道连通的通道。护套的尺寸使得其可以进入尿道并且具有长度，使得当其远端位于前列腺附近时，近端位于尿道外。具有近端和远端的一次性针组件可移除地安装在桥中的通道中并且延伸穿过护套中的通道。针组件包括至少一个针电极和同轴地设置在针电极上的绝缘套管。针组件的近端被相对于纵向轴线以一定角度侧向移动以面向尿道壁。针组件和桥的近端被携带机构，用于使针电极和绝缘套筒在其上通过尿道壁进入并进入前列腺组织中的目标体积，其中一部分电极是自由的的绝缘体，但绝缘体延伸穿过尿道壁。

5. 发明授权

US5591125A Medical probe with stylets 失效
标题翻译：医疗探头与风格
公开(公告)号：US5591125A
公开(公告)日：1997-01-07
申请号：US470621
申请日：1995-06-06
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译：本发明的医疗探针装置包括具有控制端和探针端的导管。探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变从凹槽和尖端向外。聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。

6. 发明授权

US06241702B1 Radio frequency ablation device for treatment of the prostate 失效
标题翻译：射频消融装置用于治疗前列腺
公开(公告)号：US06241702B1
公开(公告)日：2001-06-05
申请号：US09094255
申请日：1998-06-09
申请人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
发明人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
IPC分类号： A61B1720
CPC分类号： A61B18/00 , A61B10/02 , A61B10/0233 , A61B10/0241 , A61B10/0275 , A61B10/06 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M3/0279 , A61M25/0136 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/04 , A61N5/045
摘要： A medical device for the treatment by radio frequency ablation of a target volume in tissue of a prostate comprising an elongate probe member having proximal and distal extremities and having a passage therein extending from the proximal extremity to the distal extremity. The elongate probe member is sized so that it can be introduced into the urethra. At least one guide tube having proximal and distal extremities is mounted in the passage of the elongate probe member for nonlongitudinal movement therein. The at least one guide tube has a lumen extending therethrough from the proximal extremity to the distal extremity. A radio frequency conductive electrode is disposed in the lumen. A handle is coupled to the proximal extremity of the elongate probe member and includes a finger actuatable mechanism secured to the radio frequency electrode for advancing and retracting the radio frequency electrode with respect to the at least one guide tube. The distal extremity of the at least one guide tube has a curved surface for directing the radio frequency electrode sidewise of the longitudinal axis into the tissue of the prostate.
摘要翻译：一种医疗装置，用于通过射线消融前列腺组织中的目标体积进行治疗，其包括具有近端和远端的细长探针部件，并且具有从近端至远端延伸的通道。细长的探针构件的尺寸使得其可以被引入到尿道中。具有近端和远端的至少一个导管安装在细长探针构件的通道中，用于在其中非纵向移动。所述至少一个引导管具有从近端至远端延伸通过的内腔。射频导电电极设置在内腔中。手柄耦合到细长探针构件的近端，并且包括固定到射频电极的手指可致动机构，用于相对于至少一个导管推进和缩回射频电极。所述至少一个引导管的远端具有弯曲表面，用于将射频电极侧向纵向轴线引导到前列腺的组织中。

7. 发明授权

US5421819A Medical probe device 失效
标题翻译：医用探针装置
公开(公告)号：US5421819A
公开(公告)日：1995-06-06
申请号：US61647
申请日：1993-05-13
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译：本发明的医疗探针装置包括具有控制端和探针端的导管。探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于通过至少一个管心针孔将柔性探针向外引导并通过介入组织引导到靶组织。探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变从凹槽和尖端向外。聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。

8. 发明授权

US5582589A Medical probe with stylets 失效
公开(公告)号：US5582589A
公开(公告)日：1996-12-10
申请号：US465718
申请日：1995-06-06
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.

9. 发明授权

US5549644A Transurethral needle ablation device with cystoscope and method for treatment of the prostate 失效
标题翻译：具有膀胱镜的经尿道针消融装置及前列腺治疗方法
公开(公告)号：US5549644A
公开(公告)日：1996-08-27
申请号：US191258
申请日：1994-02-02
申请人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
发明人： Ingemar H. Lundquist , Stuart D. Edwards , Hugh R. Sharkey , Ronald G. Lax , James A. Baker, Jr. , Phillip R. Sommer
IPC分类号： A61N5/02 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M20060101 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B18/00 , A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/1477 , A61B18/1482 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61F2007/0054 , A61M2025/0089 , A61M2025/0091 , A61M2025/0096 , A61M2025/018 , A61M3/0279 , A61N5/04
摘要： A transurethral needle ablation device for the treatment of the prostate of a human male using radio frequency energy wall comprising a sheath having a lumen extending therethrough. A guide tube assembly is slidably mounted in the lumen in the sheath and having a lumen extending therethrough. A needle electrode is slidably mounted in the lumen in the guide tube assembly. An insulating sheath is disposed about the needle electrode so that the distal extremity of the needle electrode is exposed. A handle adapted to be gripped by the human hand is mounted on the proximal extremity of the sheath. Levers are carried by the handle for causing bending of the distal extremity of the guide tube assembly at an angle with respect to its longitudinal axis whereby the lumen in the guide tube assembly can be directed so that it faces the urethral wall. A control is carried by the handle and coupled to the needle electrode and the insulating sleeve for advancing and retracting the needle electrode with respect to the guide tube assembly whereby when the sheath is positioned in the urethra with its distal extremity in the vicinity of the prostate, the needle electrode can be advanced through the urethral wall and into the tissue of the prostate to permit the application of radio frequency energy to the tissue of the prostate surrounding the needle electrode to form a lesion in the prostate.
摘要翻译：一种用于治疗男性前列腺的经尿道针消融装置，其使用射频能量壁，其包括具有延伸穿过其中的内腔的护套。引导管组件可滑动地安装在护套中的内腔中并且具有延伸穿过其中的内腔。针电极可滑动地安装在导管组件的内腔中。绝缘护套设置在针电极周围，使得针电极的远端露出。适于被人的手抓住的手柄安装在护套的近端上。杠杆由手柄承载，以引导导管组件的远端末端相对于其纵向轴线成一定角度，由此引导管组件中的内腔可被定向以使其面向尿道壁。控制手柄由手柄承载并且联接到针电极和绝缘套筒上，用于相对于导管组件推进和缩回针电极，由此当护套定位在尿道中时，其远端在前列腺附近针状电极可以通过尿道壁前进并进入前列腺的组织，以允许将射频能量施加到针电极周围的前列腺组织，以在前列腺中形成病变。

10. 发明授权

US5435805A Medical probe device with optical viewing capability 失效
标题翻译：具有光学观察能力的医疗探针装置
公开(公告)号：US5435805A
公开(公告)日：1995-07-25
申请号：US62364
申请日：1993-05-13
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James A. Baker, Jr.
IPC分类号： A61B1/018 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1442 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/00296 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00023 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00291 , A61B2018/00327 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1412 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61B2218/003 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/0069 , A61M25/0082 , A61M3/0279 , A61N5/04
摘要： A medical probe device comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. The stylet guide housing has an optical viewing means positioned for viewing the stylet and adjacent structure which includes a fiber optic channel means for receiving a fiber optic viewing device. The fiber optic channel means can include a guide port means for directing longitudinal movement of a fiber optic device with respect to the stylet guide means in a viewing zone and a flushing liquid channel in the stylet guide housing having an exit port positioned to direct flushing liquid issuing therefrom across the end of a fiber optic device when positioned in the viewing zone. The optical viewing means can comprise a viewing window positioned in the stylet guide housing for viewing the stylet when it is directed outward from its respective stylet port. The optical viewing means can include a fiber optic channel in the stylet guide housing for receiving the a fiber optic viewing device and aligning the viewing end thereof with the viewing window. Windowed devices can include a flushing liquid channel in the stylet guide housing having an exit port positioned to direct flushing liquid issuing therefrom across a surface of the viewing window.
摘要翻译：一种医疗探针装置，其包括导管，该导管具有在其侧面具有至少一个管心针端口的探针引导壳体和用于通过至少一个通管孔向外引导柔性探针管的探针引导装置，并通过介入组织向目标组织引导。探针引导壳体具有光学观察装置，用于观察探针和相邻结构，其包括用于接收光纤观察装置的光纤通道装置。光纤通道装置可以包括引导端口装置，用于在观察区域引导光纤装置相对于探针引导装置的纵向移动，并且在通道引导壳体中的冲洗液体通道具有出口端口，定位成引导冲洗液体当定位在观察区域时，从光纤设备的端部发出。光学观察装置可以包括定位在探针引导壳体中的观察窗，用于当其从其各自的管心针端口向外指示时，用于观察探针。光学观察装置可以包括在探针引导壳体中的光纤通道，用于接收光纤观察装置并将其观察端与观察窗对准。开窗装置可以包括探针引导壳体中的冲洗液体通道，其具有出口端口，该出口端口定位成直接从其观察窗口的表面引导从其中排出的冲洗液体。

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