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1. 发明专利

IL281153D0 Direct de-differentiation of urine cell into neural stem cell using synthetic messenger rna 未知
公开(公告)号：IL281153D0
公开(公告)日：2021-04-29
申请号：IL28115321
申请日：2021-02-28
申请人： STEMLAB INC , SEUNG KWON YOU , PHIL JUN KANG , DA RYEON SON , WON JUN HONG , WON JIN YUN , JANG BO LEE , GYU MAN PARK , IN YONG KIM , JUNG HYUN PARK , JIE ZHENG , WEI WEI GAO , JI HOON JANG , EUN KYOUNG JUN , BYUNG SUN YOON
发明人： SEUNG KWON YOU , PHIL JUN KANG , DA RYEON SON , WON JUN HONG , WON JIN YUN , JANG BO LEE , GYU MAN PARK , IN YONG KIM , JUNG HYUN PARK , JIE ZHENG , WEI WEI GAO , JI HOON JANG , EUN KYOUNG JUN , BYUNG SUN YOON
IPC分类号： A61K35/30 , A61P25/28 , C12N5/0797
摘要： The present invention relates to a method for inducing reprogramming of neural stem cells from urine cells by introducing mRNAs of reprogramming factors Oct4, Sox2, Klf4, and Glis1; and a composition for the prevention or treatment of neurological damage diseases comprising the neural stem cells induced by the method as an active ingredient.

2. 发明专利

AU6186000A Liquid container 未知
公开(公告)号：AU6186000A
公开(公告)日：2001-04-30
申请号：AU6186000
申请日：2000-07-28
申请人： YONG JIN YUN
发明人： YUN YONG-JIN
IPC分类号： B65D30/00 , B65D23/04
摘要： A liquid container is provided in which an air inlet is formed integrally with the main body of the liquid container, thus allowing regulated pouring of the liquid. Such a simplified structure reduces the manufacturing cost with an increased productivity. The air inlet is extended inwardly along with an internal wall of the container from an inner circumference of the entrance, and formed to have an end thereof facing toward a grip of the container.

3. 发明专利

CA2732924A1 LED RETROFIT LAMP FOR FLUORESCENT LIGHTING FIXTURE 未知
公开(公告)号：CA2732924A1
公开(公告)日：2012-08-21
申请号：CA2732924
申请日：2011-02-21
申请人： JIN YUN BO
发明人： JIN YUN BO
IPC分类号： F21V23/00 , F21K9/27 , F21V19/00 , H01L33/00
摘要： This invention provides an improved LED retrofit lamp for existing fluorescent fixtures. The LED lamp includes an LED lighting tube equipped with power supply wires and grounding wire. The LED lighting tube is equipped with standard fluorescent lamp bases, can be mounted directly to existing fluorescent sockets. The power supply wires connect to the AC line (Live and Neutral). The grounding wire connects to the grounding conductor and the grounding point of the existing fixture.

4. 发明申请

WO2013109293A1 VALVE SYSTEM FOR INFLATABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可充气医疗器械的阀系统
公开(公告)号：WO2013109293A1
公开(公告)日：2013-07-25
申请号：PCT/US2012/025420
申请日：2012-02-16
申请人： CONVATEC TECHNOLOGIES INC. , JIN, Yun , GREGORY, Christopher, Carter
发明人： JIN, Yun , GREGORY, Christopher, Carter
IPC分类号： A61M29/02
CPC分类号： A61M25/10186 , A61F5/4405 , A61M5/3134 , A61M25/1018 , A61M25/10182 , A61M25/10184 , A61M25/1036 , A61M39/22 , A61M39/24 , A61M39/26 , A61M2039/2473 , A61M2039/2493 , Y10T29/49826
摘要： The present invention relates to a valve system for an inflatable portion of an indwelling medical device and more particularly to a valve system for fluid regulation of a catheter comprising a fluid inflatable portion that undergoes pressure changes within the body during use. The present invention also relates to methods of treatment using said valve system and indwelling medical devices comprising said valve systems.
摘要翻译：本发明涉及一种用于留置医疗装置的可膨胀部分的阀系统，更具体地涉及一种用于导管的流体调节的阀系统，该阀系统包括在使用期间在体内经受压力变化的流体可充气部分。本发明还涉及使用所述阀系统和包括所述阀系统的留置医疗装置的治疗方法。

5. 发明申请

WO2013074763A1 APPARATUS FOR PREVENTING OVER INFLATION OF THE RETENTION BALLOON IN MEDICAL CATHETERS AND AIRWAY DEVICES 审中-公开
标题翻译：用于防止在医用导管和气道装置中保留气泡的装置
公开(公告)号：WO2013074763A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/065239
申请日：2012-11-15
申请人： CONVATEC TECHNOLOGIES, INC. , GREGORY, Christopher , JIN, Yun , CLINE, John, B.
发明人： GREGORY, Christopher , JIN, Yun , CLINE, John, B.
IPC分类号： A61M25/04
CPC分类号： A61M16/044 , A61F5/445 , A61F5/449 , A61F2005/4455 , A61M3/0295 , A61M16/04 , A61M16/0443 , A61M16/0465 , A61M16/0486 , A61M16/201 , A61M16/208 , A61M16/209 , A61M25/10182 , A61M25/10183 , A61M25/10185 , A61M25/10186 , A61M25/10187 , A61M2205/583
摘要： The body has a fluid inlet port for receiving pressurized fluid and a fluid outlet port connected to the retention balloon. A first passage connects the fluid inlet port and the fluid outlet port, A second passage in the body is connected to the balloon fluid return path and is at the pressure of the retention balloon. A. valve prevents fluid flow through the first passage when actuated. The valve includes a pressure-responsive member movable to a position to obstruct fluid flow in response to fluid pressure in the second passage exceeding the predetermined level. Flexible means such as a membrane defines a normally open portion of the first fluid passage, which is closed by the moveable means bearing on the membrane when pressure exceeding the predetermined level actuates the valve.
摘要翻译：主体具有用于接收加压流体的流体入口和连接到保持气囊的流体出口。第一通道连接流体入口和流体出口。主体中的第二通道连接到气囊流体返回路径并处于保持气囊的压力。当阀门致动时，阀门阻止流体流过第一通道。所述阀包括压力响应构件，所述压力响应构件能够响应于所述第二通道中的流体压力超过预定水平位置而阻止流体流动的位置。诸如膜的柔性装置限定第一流体通道的常开部分，当超过预定水平的压力促使阀门时，第一流体通道的常开部分由在膜上的可移动装置关闭。

6. 发明申请

WO2012076435A1 PYRIMIDINONE COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES OR CONDITIONS MEDIATED BY LP - PLA2 审中-公开
标题翻译：用于治疗由LP-PLA2介导的疾病或病症的吡咯咪嗪化合物
公开(公告)号：WO2012076435A1
公开(公告)日：2012-06-14
申请号：PCT/EP2011/071690
申请日：2011-12-05
申请人： GLAXO GROUP LIMITED , JIN, Yun , WAN, Zehong , ZHANG, Qing
发明人： JIN, Yun , WAN, Zehong , ZHANG, Qing
IPC分类号： C07D239/36 , C07D239/47 , C07D239/52 , C07D239/56 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D413/06 , C07D417/06
CPC分类号： C07D403/14 , A61K31/505 , A61K31/506 , C07D239/22 , C07D239/36 , C07D239/47 , C07D239/52 , C07D239/56 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D413/06 , C07D417/06
摘要： The present invention relates to novel compounds that inhibit Lp-PLA 2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA 2 , for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema (I).
摘要翻译：本发明涉及抑制Lp-PLA2活性的新型化合物，其制备方法，含有它们的组合物及其用于治疗与Lp-PLA2的活性有关的疾病，例如动脉粥样硬化，阿尔茨海默病和/ 或糖尿病性黄斑水肿（I）。

7. 发明申请

WO2011106388A1 SAFETY DRUG DELIVERY SYSTEM 审中-公开
标题翻译：安全药物输送系统
公开(公告)号：WO2011106388A1
公开(公告)日：2011-09-01
申请号：PCT/US2011/025877
申请日：2011-02-23
申请人： BECTON, DICKINSON AND COMPANY , WU, Yongxian , JIN, Yun , AON, Mitali
发明人： WU, Yongxian , JIN, Yun , AON, Mitali
IPC分类号： A61M5/165 , A61M39/26
CPC分类号： A61M5/165 , A61M39/26 , A61M2005/1652
摘要： Drug delivery systems are provided that include an actuator assembly (200) permanently attached to a filter (300) for connection of a container containing medications such as epidural anesthesia, to a delivery site. In one or more embodiments, the actuator assembly includes a projection with an opening extending from a distal end of the actuator assembly in a proximal direction and the filter includes an inlet and an outlet in fluid communication with the opening. The filter includes a housing (310) including two plates joined together or a cylindrical body defining a cavity containing filter materials. A conduit may be attached to the outlet of the filter to allow connection of the drug delivery systems described to a delivery site, such as a catheter. Methods of administering a medication to a delivery site are also provided.
摘要翻译：提供了药物递送系统，其包括永久地附接到过滤器（300）的致动器组件（200），用于将含有药物如硬膜外麻醉的容器连接到输送部位。在一个或多个实施例中，致动器组件包括具有从致动器组件的远端沿近端方向延伸的开口的突起，并且过滤器包括与开口流体连通的入口和出口。过滤器包括包括连接在一起的两个板的壳体（310）或限定包含过滤材料的空腔的圆柱体。导管可以连接到过滤器的出口，以允许所描述的药物递送系统连接到输送部位，例如导管。还提供了将药物施用于递送部位的方法。

8. 发明申请

WO2010076766A1 GENES ASSOCIATED WITH PLANT TILLER NUMBER AND USES THEREOF 审中-公开
标题翻译：与植物蘖数相关的基因及其用途
公开(公告)号：WO2010076766A1
公开(公告)日：2010-07-08
申请号：PCT/IB2009/055988
申请日：2009-12-29
申请人： INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY , SYNGENTA PARTICIPATIONS AG , CHENGCAI, Chu , HONGNING, Tong , JIN, Yun , LIU, Wenbo , LI, Feng , FANG, Jun , ZHU, Lihuang
发明人： CHENGCAI, Chu , HONGNING, Tong , JIN, Yun , LIU, Wenbo , LI, Feng , FANG, Jun , ZHU, Lihuang
IPC分类号： C12N15/29 , C07K14/415 , C12N15/82 , A01H5/00 , A01H5/10
CPC分类号： C07K14/415 , C12N15/8298
摘要： Compositions and methods for altering plant tiller number using dwarf and low tillering (DLT) genes.
摘要翻译：使用矮秆和低分蘖（DLT）基因改变植物分蘖数的组合物和方法。

9. 发明申请

WO2010011036A3 PHOTONIC CRYSTAL DEVICE PRODUCED BY A WET PROCESS, AND A PRODUCTION METHOD THEREOF 审中-公开
标题翻译：由湿法生产的光子晶体装置及其生产方法
公开(公告)号：WO2010011036A3
公开(公告)日：2010-04-15
申请号：PCT/KR2009003703
申请日：2009-07-07
申请人： KOREA ELECTRO TECH RES INST , KIM JUNG-IL , JEON SEOK-GY , JIN YUN-SIK , KIM GEUN-JU , SON CHAE-HWA , PARK SI-HYUN , HAN SEONG TAE , KIM JONG UK
发明人： KIM JUNG-IL , JEON SEOK-GY , JIN YUN-SIK , KIM GEUN-JU , SON CHAE-HWA , PARK SI-HYUN , HAN SEONG TAE , KIM JONG UK
IPC分类号： H01L21/306 , H01L21/20 , H01L21/3063
CPC分类号： G02B6/1225 , B82Y20/00 , G02B6/13
摘要： The present invention relates to a method for producing a photonic crystal device having a photonic crystal structure which can be used in photonic crystal devices such as optical waveguides, resonators, filters, antennas and Smith-Purcell free electron lasers which can be employed in a desired electromagnetic waveband by application of semiconductor processing technology and of an anisotropic wet process which uses the crystallization direction (100) of a silicon wafer; for producing a photonic crystal device which comprises a photonic crystal part having a periodic array of silicon crystals having a predetermined form and a covering part for reducing optical losses in the axial direction to be used as an optical waveguide or a resonator, thereby to be capable of being applied in a desired electromagnetic band; and which can have the conductive photonic-crystal characteristics by not coating the silicon crystal with an electrically conductive material and the metal photonic-crystal characteristics by coating the silicon crystal with an electrically conductive material. This production method makes it possible to mass-produce photonic crystal structures of relatively low cost and substantial height within a short time.
摘要翻译：本发明涉及一种用于制造具有光子晶体结构的光子晶体器件的方法，该光子晶体结构可以用于光子晶体器件，例如光波导，谐振器，滤波器，天线和Smith-Purcell自由电子激光器，其可以用于期望的通过应用半导体处理技术的电磁波段以及使用硅晶片的结晶方向（100）的各向异性湿法工艺; 用于制造光子晶体器件，该光子晶体器件包括具有预定形状的具有周期性的硅晶体阵列的光子晶体部分和用于降低沿轴向的光学损耗以用作光波导或谐振器的覆盖部分，从而能够应用于所需的电磁波段; 并且通过不用导电材料涂覆硅晶体而具有导电光子晶体特性，并且通过用导电材料涂覆硅晶体而具有金属光子晶体特性。该制造方法能够在短时间内批量生产成本相对较低且高度相当高的光子晶体结构。

10. 发明申请

WO2007070263A3 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS 审中-公开
标题翻译：使用离子液体催化剂的苯胺或苯胺衍生物的环烷基化
公开(公告)号：WO2007070263A3
公开(公告)日：2007-08-02
申请号：PCT/US2006046066
申请日：2006-12-01
申请人： CHEMTURA CORP , HOBBS STEVEN J , MADABUSI VENKAT , WANG JIN-YUN , STIEBER JOSEPH F
发明人： HOBBS STEVEN J , MADABUSI VENKAT , WANG JIN-YUN , STIEBER JOSEPH F
IPC分类号： C07C209/68 , C07C211/45 , C07C211/47
CPC分类号： C07C209/68 , C07C211/45 , C07C211/47
摘要： A process for ring-alkylating aniline or an aniline derivative in which aniline or an aniline derivative is reacted with an alkylating agent in the presence of an ionic liquid which includes a Lewis acid and a quaternary cation, to produce a ring-alkylated alkylaniline .or a ring-alkylated aniline derivative. The use of an ionic liquid permits convenient separation of the alkylated reaction product from the reactants.
摘要翻译：一种苯胺或苯胺衍生物的环烷基化方法，其中苯胺或苯胺衍生物与烷基化剂在包含路易斯酸和季阳离子的离子液体存在下反应，生成环烷基化的烷基苯胺，或环烷基化苯胺衍生物。使用离子液体可以方便地将烷基化反应产物与反应物分离。

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