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1. 发明申请

WO2011106388A1 SAFETY DRUG DELIVERY SYSTEM 审中-公开
标题翻译：安全药物输送系统
公开(公告)号：WO2011106388A1
公开(公告)日：2011-09-01
申请号：PCT/US2011/025877
申请日：2011-02-23
申请人： BECTON, DICKINSON AND COMPANY , WU, Yongxian , JIN, Yun , AON, Mitali
发明人： WU, Yongxian , JIN, Yun , AON, Mitali
IPC分类号： A61M5/165 , A61M39/26
CPC分类号： A61M5/165 , A61M39/26 , A61M2005/1652
摘要： Drug delivery systems are provided that include an actuator assembly (200) permanently attached to a filter (300) for connection of a container containing medications such as epidural anesthesia, to a delivery site. In one or more embodiments, the actuator assembly includes a projection with an opening extending from a distal end of the actuator assembly in a proximal direction and the filter includes an inlet and an outlet in fluid communication with the opening. The filter includes a housing (310) including two plates joined together or a cylindrical body defining a cavity containing filter materials. A conduit may be attached to the outlet of the filter to allow connection of the drug delivery systems described to a delivery site, such as a catheter. Methods of administering a medication to a delivery site are also provided.
摘要翻译：提供了药物递送系统，其包括永久地附接到过滤器（300）的致动器组件（200），用于将含有药物如硬膜外麻醉的容器连接到输送部位。在一个或多个实施例中，致动器组件包括具有从致动器组件的远端沿近端方向延伸的开口的突起，并且过滤器包括与开口流体连通的入口和出口。过滤器包括包括连接在一起的两个板的壳体（310）或限定包含过滤材料的空腔的圆柱体。导管可以连接到过滤器的出口，以允许所描述的药物递送系统连接到输送部位，例如导管。还提供了将药物施用于递送部位的方法。

2. 发明申请

WO2007084796A3 IONIC POLYMER DEVICES AND METHODS OF FABRICATING THE SAME 审中-公开
标题翻译：离子聚合物装置及其制造方法
公开(公告)号：WO2007084796A3
公开(公告)日：2008-07-17
申请号：PCT/US2007001853
申请日：2007-01-23
申请人： HITACHI CHEMICAL RES CT INC , HITACHI CHEMICAL CO LTD , WU YONGXIAN , LI YANGYANG
发明人： WU YONGXIAN , LI YANGYANG
IPC分类号： C08J5/20
CPC分类号： H01M4/8642 , C08J5/20 , F03G7/005 , H01B1/122
摘要： An embodiment provides an ionic polymer device comprising two extended electrode layers comprising a plurality of conductive particles, wherein the plurality of conductive particles form a concentration gradient in each of the two extended electrode layers, an ionic polymer dielectric layer between two extended electrode layers, and at least one conductive layer on outer surfaces of two extended electrode layers. Another embodiment provides an ionic polymer device comprising a polymer composite with a plurality of surface features on two opposite surfaces, and at least one conductive layer on each of said two opposite surfaces. One embodiment provides a method of making an ionic polymer device, comprising forming a partially cured polymer-metallic salt layer, reducing the metallic salt to form a plurality of metal particles, thereby forming a first extended electrode layer and a second extended electrode layer at and near opposite surfaces of the ionic polymer device.
摘要翻译：一个实施方案提供了一种离子聚合物装置，其包含两个包括多个导电颗粒的延伸电极层，其中多个导电颗粒在两个延伸电极层中的每一个中形成浓度梯度，在两个延伸电极层之间形成离子聚合物电介质层，在两个延伸的电极层的外表面上的至少一个导电层。另一个实施方案提供了一种离子聚合物装置，其包括在两个相对表面上具有多个表面特征的聚合物复合物，以及在所述两个相对表面中的每一个上的至少一个导电层。一个实施方案提供了一种制备离子聚合物装置的方法，包括形成部分固化的聚合物金属盐层，还原金属盐以形成多个金属颗粒，由此在其上形成第一延伸电极层和第二延伸电极层，靠近离子聚合物装置的相对表面。

3. 发明申请

WO2008045301A1 WELL-ALIGNED, HIGH ASPECT-RATIO, HIGH-DENSITY SILICON NANOWIRES AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：高对比度，高比例，高密度硅纳米微粒及其制备方法
公开(公告)号：WO2008045301A1
公开(公告)日：2008-04-17
申请号：PCT/US2007/021348
申请日：2007-10-05
申请人： HITACHI CHEMICAL CO., LTD. , HITACHI CHEMICAL RESEARCH CENTER, INC. , WU, Yongxian
发明人： WU, Yongxian
IPC分类号： H01L27/00
CPC分类号： H01L31/035281 , B82Y10/00 , H01L29/0665 , H01L31/072 , Y02E10/50 , Y10S438/93 , Y10S438/962 , Y10S977/762 , Y10S977/768 , Y10S977/789
摘要： A method of producing silicon nanowires includes providing a substrate in the form of a doped material; formulating an etching solution; and applying an appropriate current density for an appropriate length of time. Related structures and devices composed at least in part from silicon nanowires are also described.
摘要翻译：一种制造硅纳米线的方法包括提供掺杂材料形式的衬底; 配制蚀刻溶液; 并施加适当的电流密度适当的时间长度。还描述了至少部分由硅纳米线组成的相关结构和器件。

4. 发明申请

WO2012015781A3 BLUNT NEEDLE SAFETY DRUG DELIVERY SYSTEM 审中-公开
标题翻译： BLUNT针头安全药物递送系统
公开(公告)号：WO2012015781A3
公开(公告)日：2012-05-31
申请号：PCT/US2011045281
申请日：2011-07-26
申请人： BECTON DICKINSON CO , WU YONGXIAN , JIN YUN
发明人： WU YONGXIAN , JIN YUN
IPC分类号： A61M5/165 , A61J1/20
CPC分类号： A61M5/34 , A61J1/2096 , A61M5/165 , A61M39/26 , A61M2039/1077 , A61M2039/1094 , A61M2205/273
摘要： Drug delivery devices having non-luer connections and adapters and adaption connectors for providing non-luer connections to drug delivery devices are provided. An exemplary drug delivery device for use with a catheter connection includes a blunt needle component (110) with a non-luer connection (120) and a filter component (140) with a non-luer connection (160), wherein the non-luer connections (120, 160) of the blunt needle component and filter component are incompatible with standard luer fitting and intravenous route - accessing devices.
摘要翻译：提供了具有非路厄尔连接和适配器的药物输送装置以及用于向药物输送装置提供非路厄尔连接的适配连接器。用于导管连接的示例性药物递送装置包括具有非路厄连接（120）的钝针组件（110）和具有非路厄连接（160）的过滤器部件（140），其中非路厄钝针组件和过滤器组件的连接（120,160）与标准鲁尔接头和静脉通路接入设备不兼容。

5. 发明申请

WO2012024370A1 NON-LUER CONNECTORS 审中-公开
标题翻译：非接头连接器
公开(公告)号：WO2012024370A1
公开(公告)日：2012-02-23
申请号：PCT/US2011/048034
申请日：2011-08-17
申请人： BECTON, DICKINSON AND COMPANY , JIN, Yun , WU, Yongxian , MATHUR, Devesh
发明人： JIN, Yun , WU, Yongxian , MATHUR, Devesh
IPC分类号： A61M39/10
CPC分类号： A61M39/10 , A61M2039/1094
摘要： Drug delivery devices having integrated non-luer connectors are described. An exemplary drug delivery device includes a container with a non-luer connector that prevents connection of a standard female luer connector to the container. One or more embodiments pertain to a container with a non-luer connector that prevents the formation of a fluid-tight seal between a standard female luer connector and the container. A non-luer connector for attachment to a container having a non-luer element is also described.
摘要翻译：描述具有集成非路厄连接器的药物输送装置。示例性药物递送装置包括具有非路厄连接器的容器，其防止标准母鲁尔连接器与容器的连接。一个或多个实施例涉及具有非路厄连接器的容器，其防止在标准母路厄尔连接器和容器之间形成流体密封。还描述了用于附接到具有非路厄元件的容器的非路厄连接器。

6. 发明申请

WO2012015781A2 BLUNT NEEDLE SAFETY DRUG DELIVERY SYSTEM 审中-公开
标题翻译： BLUNT针头安全药物递送系统
公开(公告)号：WO2012015781A2
公开(公告)日：2012-02-02
申请号：PCT/US2011/045281
申请日：2011-07-26
申请人： BECTON, DICKINSON AND COMPANY , WU, Yongxian , JIN, Yun
发明人： WU, Yongxian , JIN, Yun
IPC分类号： A61M5/165
CPC分类号： A61M5/34 , A61J1/2096 , A61M5/165 , A61M39/26 , A61M2039/1077 , A61M2039/1094 , A61M2205/273
摘要： Drug delivery devices having non-luer connections and adapters and adaption connectors for providing non-luer connections to drug delivery devices are provided. An exemplary drug delivery device for use with a catheter connection includes a blunt needle component with a non-luer connection and a filter component with a non-luer connection, wherein the non-luer connections of the blunt needle component and filter component are incompatible with standard luer fitting and intravenous route-accessing devices. In one or more embodiments, an adapter having a non-luer connection at one end and a luer connector is provided for use with blunt needle components and filter components wherein one of the blunt needle component and the filter component includes a luer connection and the other of the blunt needle component and the filter component includes a non-luer connection. Methods of delivering liquid medication to a catheter are also provided.
摘要翻译：提供了具有非路厄尔连接和适配器的药物输送装置以及用于向药物输送装置提供非路厄尔连接的适配连接器。与导管连接一起使用的示例性药物递送装置包括具有非路厄连接的钝针部件和具有非路厄连接的过滤器部件，其中钝针部件和过滤器部件的非路厄连接不与标准鲁尔接头和静脉插管设备。在一个或多个实施例中，提供了在一端具有非路厄连接和鲁尔连接器的适配器，用于钝针部件和过滤器部件，其中钝针部件和过滤器部件中的一个包括鲁尔连接件，而另一个钝针组件和过滤器部件包括非路厄尔连接。还提供了将液体药物递送到导管的方法。

7. 发明申请

WO2011106374A1 SAFETY DRUG DELIVERY CONNECTORS 审中-公开
标题翻译：安全药物输送连接器
公开(公告)号：WO2011106374A1
公开(公告)日：2011-09-01
申请号：PCT/US2011/025858
申请日：2011-02-23
申请人： BECTON, DICKINSON AND COMPANY , WU, Yongxian , JIN, Yun , AON, Mitali , GARRISON, Michael D.
发明人： WU, Yongxian , JIN, Yun , AON, Mitali , GARRISON, Michael D.
IPC分类号： A61M39/24 , A61M39/26
CPC分类号： A61M39/24 , A61J1/201 , A61J1/2037 , A61J1/2051 , A61J1/2096 , A61M39/26 , A61M2039/248 , A61M2039/261
摘要： Drug delivery connectors are provided for permitting and blocking fluid flow between a container and a catheter connector or other drug delivery site. The drug delivery connectors includes a ball valve (100) for forming a releasable seal within the drug delivery connectors. In one or more embodiments, the ball valve prevents fluid flow between an open proximal end and an open distal end the drug delivery connector and the ball (190) is movable in a proximal direction to release the releasable seal to permit fluid flow from the open proximal direction to the open distal direction. Methods of delivering medication to a catheter connector that includes an actuator (200) are also provided.
摘要翻译：药物递送连接器用于允许和阻止容器和导管连接器或其它药物递送部位之间的流体流动。药物递送连接器包括用于在药物递送连接器内形成可释放密封的球阀（100）。在一个或多个实施例中，球阀防止流体在开放的近端和开放远端之间流动，药物输送连接器和球（190）可在近端方向上移动以释放可释放的密封，以允许流体从开口近端方向到开放的远端方向。还提供将药物递送到包括致动器（200）的导管连接器的方法。

8. 发明申请

WO2007084796A2 IONIC POLYMER DEVICES AND METHODS OF FABRICATING THE SAME 审中-公开
标题翻译：离子聚合物装置及其制造方法
公开(公告)号：WO2007084796A2
公开(公告)日：2007-07-26
申请号：PCT/US2007/001853
申请日：2007-01-23
申请人： HITACHI CHEMICAL RESEARCH CENTER, INC. , HITACHI CHEMICAL CO., LTD. , WU, Yongxian , LI, Yangyang
发明人： WU, Yongxian , LI, Yangyang
IPC分类号： H01M4/00
CPC分类号： H01M4/8642 , C08J5/20 , F03G7/005 , H01B1/122
摘要： An embodiment provides an ionic polymer device comprising two extended electrode layers comprising a plurality of conductive particles, wherein the plurality of conductive particles form a concentration gradient in each of the two extended electrode layers; an ionic polymer dielectric layer between two extended electrode layers; and at least one conductive layer on outer surfaces of two extended electrode layers. Another embodiment provides an ionic polymer device comprising a polymer composite with a plurality of surface features on two opposite surfaces; and at least one conductive layer on each of said two opposite surfaces. One embodiment provides a method of making an ionic polymer device, comprising forming a partially cured polymer-metallic salt layer, reducing the metallic salt to form a plurality of metal particles, thereby forming a first extended electrode layer and a second extended electrode layer at and near opposite surfaces of the ionic polymer device. Another embodiment provides a method of making an ionic polymer device, comprising providing at least one mixture comprising a plurality of conductive particles in an ionic polymer solution; forming at least one extended electrode layer comprising a plurality of conductive particles by curing the at least one mixture; providing an ionic polymer dielectric layer on one of the at least one extended electrode layer; and depositing at least one conductive layer on the outer surface of the at least one extended electrode layer. Yet another embodiment provides a method of making an ionic polymer device, comprising providing at least one imprinting plate; providing an ionic polymer solution; and applying the ionic polymer solution on the at least one imprinting plate, thereby forming at least one imprinted polymer layer with surface features.
摘要翻译：一个实施方案提供了一种离子聚合物装置，其包括两个包括多个导电颗粒的延伸电极层，其中多个导电颗粒在两个延伸电极层中的每一个中形成浓度梯度; 两个延伸电极层之间的离子聚合物电介质层; 以及在两个延伸电极层的外表面上的至少一个导电层。另一个实施方案提供了一种离子聚合物装置，其包括在两个相对表面上具有多个表面特征的聚合物复合材料; 以及在所述两个相对表面中的每一个上的至少一个导电层。一个实施方案提供了一种制备离子聚合物装置的方法，包括形成部分固化的聚合物金属盐层，还原金属盐以形成多个金属颗粒，由此在其上形成第一延伸电极层和第二延伸电极层，靠近离子聚合物装置的相对表面。另一个实施方案提供了一种制备离子聚合物装置的方法，包括在离子聚合物溶液中提供包含多个导电颗粒的至少一种混合物; 通过固化所述至少一种混合物形成包含多个导电颗粒的至少一个延伸电极层; 在所述至少一个延伸电极层之一上提供离子聚合物电介质层; 以及在所述至少一个延伸电极层的外表面上沉积至少一个导电层。另一个实施方案提供了一种制备离子聚合物装置的方法，包括提供至少一个压印板; 提供离子聚合物溶液; 以及将所述离子聚合物溶液施加在所述至少一个压印板上，从而形成具有表面特征的至少一个压印聚合物层。

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