专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06680284B1 Method for producing powdery particle-reduced formulations with the aid of compressed gases 失效
标题翻译：借助于压缩气体生产粉末颗粒减少配方的方法
公开(公告)号：US06680284B1
公开(公告)日：2004-01-20
申请号：US10030035
申请日：2002-01-03
申请人： Jürgen Heidlas , Martin Ober , Johann Wiesmüller
发明人： Jürgen Heidlas , Martin Ober , Johann Wiesmüller
IPC分类号： A01N2512
CPC分类号： A61K9/14 , A61K9/1617 , Y10S514/959 , Y10S516/922 , Y10S516/928
摘要： For the preparation of pulverulent particle-reduced formulations with the aid of compressed gases, the solid compound to be formulated, a poorly soluble and usually bioactive active compound, is homogeneously ground together with 10-99% by weight (based on the formulation) of a carrier material which is essentially soluble in the compressed gas mixture, in the presence of compressed gas or mixtures thereof in a stirred autoclave having a mechanical grinding device at process temperatures between 10 and 200° C. and at process pressures between 5 and 500 bar, and in a second process stage the compressed gas mixture, usually dimethyl ether, pure propane and/or carbon dioxide, is expanded by lowering the pressure and separated off from the homogenate, which can also be present as a melt. Finally, the pulverulent particle-reduced formulation is recovered from the homogenate obtained, with which significant improvements in the solubility properties and in particular in the bioavailability of originally poorly soluble and nonsoluble compounds are to be achieved.
摘要翻译：为了在压缩气体的帮助下制备粉末颗粒减少的制剂，将待配制的固体化合物，难溶性和通常为生物活性的活性化合物与10-99重量％（基于制剂）均匀地研磨在压缩气体或其混合物的存在下，基本上可溶于压缩气体混合物的载体材料在具有机械研磨装置的搅拌高压釜中，处理温度为10-200℃，过程压力为5至500巴，并且在第二工艺阶段，压缩气体混合物，通常是二甲醚，纯丙烷和/或二氧化碳，通过降低压力而膨胀，并从匀浆中分离，其也可以熔体形式存在。最后，从获得的匀浆中回收粉末颗粒减少的制剂，其中可以实现溶解性能，特别是原始难溶性和不溶性化合物的生物利用度的显着改善。

2. 发明授权

US07186768B2 Silane-modified oxidic or siliceous filler, process for its production and its use 有权
标题翻译：硅烷改性的氧化或硅质填料，其生产和使用的过程
公开(公告)号：US07186768B2
公开(公告)日：2007-03-06
申请号：US10423901
申请日：2003-04-25
申请人： Karsten Korth , Kurt Eichenauer , Reimund Pieter , Oliver Klockmann , Jürgen Heidlas , Martin Ober , Rudolf Zobel
发明人： Karsten Korth , Kurt Eichenauer , Reimund Pieter , Oliver Klockmann , Jürgen Heidlas , Martin Ober , Rudolf Zobel
IPC分类号： C08K3/18
CPC分类号： C08K9/06 , A61K8/25 , A61K8/585 , A61K2800/412 , A61K2800/612 , A61Q11/00 , A61Q19/00 , C01P2004/54 , C01P2004/61 , C01P2006/12 , C01P2006/14 , C01P2006/16 , C08K3/013 , C08K3/22 , C08K3/34 , C09C1/3036 , C09C1/3081 , C09C1/3684 , C09C3/12 , C09D7/62 , C09D7/69 , C09D11/03 , C08L21/00
摘要： Silane-modified oxidic or siliceous filler with a bead fraction below 75 μm of less than 15 wt. % and a median particle size distribution between of 150 to 500 μm, which is produced by the reaction of at least one microbeaded or microgranular, oxidic or siliceous filler in a compressed gas with at least one silane. The silane-modified oxidic or siliceous fillers are used in rubber compounds.
摘要翻译：硅烷改性的氧化或硅质填料，珠粒分数低于75μm，小于15wt。％和通过至少一种微珠或微粒，氧化或硅质填料在压缩气体中与至少一种硅烷反应而产生的150至500μm之间的中值粒度分布。硅烷改性的氧化或硅质填料用于橡胶混合物中。

3. 发明授权

US06599533B1 Homogenous water-free formulations containing glycerophospholipids and polar or lipophilic substances, method for the production thereof 失效
标题翻译：含有甘油磷脂和极性或亲脂性物质的均匀的无水配方，其生产方法
公开(公告)号：US06599533B1
公开(公告)日：2003-07-29
申请号：US09381530
申请日：1999-09-21
申请人： Jürgen Heidlas , Karl-Heinz Zirzow , Johann Wiesmüller , Jürgen Graefe
发明人： Jürgen Heidlas , Karl-Heinz Zirzow , Johann Wiesmüller , Jürgen Graefe
IPC分类号： A61K914
CPC分类号： C07H11/04 , A01N25/04 , A23D9/013 , A23J7/00 , A23L29/10 , A61K8/553 , A61K8/675 , A61K8/676 , A61K8/678 , A61K9/145 , A61K47/24 , A61K2800/43 , A61K2800/52 , A61Q19/00 , B01F17/0064 , C05F11/00 , C07F9/103
摘要： This invention relates to homogeneous, anhydrous formulations which contain glycerophospholipids and polar or lipophilic substances (eg, physiologically active ingredients) in a molar ratio of 1:0.001 to 1:2, and maybe anhydrous formulation aids, eg, in the form of glycerol, in a molar ratio of 1:0.001 to 1:1, expressed in terms of the glycerophospholipids, the components forming such stable aggregates with one another as to render the formulations ideal for the preparation of dispersions, emulsions and/or suspensions in many fields of application, these including the food-processing sector, biotechnology, and the pharmaceuticals industry. The formulations are produced in an extraction column using compressed hydrocarbons, and are obtained from the column as a melt.
摘要翻译：本发明涉及含有摩尔比为1:0.001-1:2的甘油磷脂和极性或亲脂性物质（例如生理活性成分）的均匀的无水制剂，以及可能是无水制剂助剂，例如以甘油的形式，以相对于甘油磷脂表示的摩尔比为1:0.001-1:1，这些组分彼此形成这样的稳定的聚集体，以使制剂成为制备分散体，乳液和/或悬浮液在许多领域中的理想选择应用，包括食品加工部门，生物技术和制药行业。制剂在使用压缩烃的萃取塔中制备，并且作为熔体从塔中获得。

4. 发明授权

US07576039B2 Additive for drilling fluids 失效
标题翻译：钻井液添加剂
公开(公告)号：US07576039B2
公开(公告)日：2009-08-18
申请号：US11316325
申请日：2005-12-22
申请人： Johann Huber , Johann Plank , Jürgen Heidlas , Gregor Keilhofer , Peter Lange
发明人： Johann Huber , Johann Plank , Jürgen Heidlas , Gregor Keilhofer , Peter Lange
IPC分类号： C09K8/035 , C09K8/12 , E21B43/22
CPC分类号： C09K8/035 , C09K8/506 , C09K8/508 , C09K2208/12
摘要： Subject matter of the present invention is a drilling fluid additive based on sulfonated asphalt, which comprises a water soluble and anionic polymer component in quantities of 0.1 to 20 wt. %, with respect to the total additive in addition to the asphalt component. With this additive the water solubility of sulfonated asphalt can be markedly increased. This additive, whose polymer component is thermally highly stable, is utilized primarily in water- and/or oil-based drilling fluids and in particular in the exploration of subterraneous petroleum and natural gas deposits. Typical polymer components to consider are representatives of polycondensation products, such as phenol resins, ketone resins and sulfonated naphthalene, acetone and amino plasticizer resins (for example urea and melamine resins).
摘要翻译：本发明的主题是基于磺化沥青的钻井液添加剂，其包含0.1至20重量％的水溶性和阴离子聚合物组分。％，相对于除了沥青组分之外的总添加剂。使用这种添加剂可以显着提高磺化沥青的水溶性。聚合物组分热稳定性高的添加剂主要用于水和/或油基钻井液中，特别是在探索地下石油和天然气矿床时。要考虑的典型聚合物组分是缩聚产物的代表，例如酚醛树脂，酮树脂和磺化萘，丙酮和氨基增塑树脂（例如脲和三聚氰胺树脂）。

5. 发明授权

US07713581B2 Method of impregnating a carrier a matrix with solid and/or liquid compounds using compressed gases, and materials thus impregnated 有权
标题翻译：用固体和/或液体化合物使用压缩气体浸渍载体载体的方法以及如此浸渍的材料
公开(公告)号：US07713581B2
公开(公告)日：2010-05-11
申请号：US11598484
申请日：2006-11-09
申请人： Jürgen Heidlas , Zhengfeng Zhang , Kurt Stork , Johann Wiesmüller , Martin Ober , Johann Obersteiner
发明人： Jürgen Heidlas , Zhengfeng Zhang , Kurt Stork , Johann Wiesmüller , Martin Ober , Johann Obersteiner
IPC分类号： B05D7/00 , B05D3/04 , B01J13/02 , A61J3/07
CPC分类号： C08J9/122 , A01C1/06 , A01N25/00 , A23K40/00 , A23L5/00 , A23L5/30 , A23V2002/00 , C08J2201/032 , C08J2203/06 , C08J2203/08 , Y02P20/544 , A23V2300/44
摘要： The invention relates to a method for impregnating a support matrix with solid and/or liquid compounds using a compressed gas or a compressed mixture of gases at densities ranging from 0.15 to 1.3 kg/l and at least two unsymmetrical pressure changes (pulsations). The method is further characterized in that both a multitude of impregnating substances such as biologically active compounds, technical materials or metal-organic compounds, as well as support matrices of biological origin and organic or inorganic substances can be used that have large inner surfaces and/or inner surfaces that are difficult to access.
摘要翻译：本发明涉及一种使用压缩气体或压缩的浓度为0.15-1.3kg / l和至少两个不对称压力变化（脉动）的气体的固体和/或液体化合物浸渍载体基质的方法。该方法的特征还在于，可以使用诸如生物活性化合物，工业材料或金属有机化合物的许多浸渍物质，以及生物来源的支持基质和有机或无机物质，其具有大的内表面和/ 或难以进入的内表面。

6. 发明申请

US20100062952A1 Copolymer based on olefinic sulphonic acids 审中-公开
标题翻译：基于烯烃磺酸的共聚物
公开(公告)号：US20100062952A1
公开(公告)日：2010-03-11
申请号：US12590673
申请日：2009-11-12
申请人： Andrea Fenchl , Christian Spindler , Jürgen Heidlas , Johann Plank
发明人： Andrea Fenchl , Christian Spindler , Jürgen Heidlas , Johann Plank
IPC分类号： C09K8/02 , C09K8/44
CPC分类号： C09K8/42 , C04B24/166 , C04B24/42 , C04B2103/46 , C08F216/1416 , C08F220/26 , C08F220/56 , C08F220/58 , C08F228/02 , C08F230/08 , C09K8/035 , C09K8/467 , C09K8/487
摘要： A copolymer based on olefinic sulphonic acids as monomer component a) and an organosilicone-containing compound as reactive component b) is proposed, for which in particular 2-acrylamido-2-methylpropanesulphonic acid (AMPS®) is suitable as component a) and vinyltrimethoxysilane, vinyltriethoxysilane and trichlorosilane as component b). This copolymer, which may have a molecular weight of from 5,000 to 5,000,000 g/mol, may also comprise further reaction components c) and d) in addition to the two main components for which further reaction components (meth)acrylamides or vinyl ethers are suitable. These copolymers, which are obtainable in particular by precipitation or gel polymerizations, are used in particular in applications in construction chemistry and here especially as water retention agents and fluid loss additives in drilling fluids and for well cementing. The novel copolymers are distinguished by pronounced thermal stability, which is displayed especially under difficult pressure conditions and at high salinities.
摘要翻译：提出了基于烯烃磺酸作为单体组分a）和含有机硅氧烷化合物作为反应组分b）的共聚物，其中特别是2-丙烯酰胺基-2-甲基丙磺酸（AMPS）适合作为组分a）和乙烯基三甲氧基硅烷乙烯基三乙氧基硅烷和三氯硅烷作为组分b）。除了其它反应组分（甲基）丙烯酰胺或乙烯基醚是合适的两种主要成分之外，该共聚物可以具有5,000至5,000,000g / mol的分子量的其它反应组分c）和d）。特别是通过沉淀或凝胶聚合可获得的这些共聚物特别用于建筑化学应用中，尤其用于钻井液中的保水剂和流体损失添加剂以及用于固井的物质。新型共聚物的特征在于明显的热稳定性，其特别在困难的压力条件下和高盐度下显示。

7. 发明授权

US07462221B2 Process and device for the extraction of substances from silane-modified fillers 有权
标题翻译：从硅烷改性填料中提取物质的方法和装置
公开(公告)号：US07462221B2
公开(公告)日：2008-12-09
申请号：US11157919
申请日：2005-06-22
申请人： Karsten Korth , Jürgen Heidlas , Kurt Stork , Rudolf Zobel
发明人： Karsten Korth , Jürgen Heidlas , Kurt Stork , Rudolf Zobel
IPC分类号： B01D53/02
CPC分类号： B01D11/0203 , B01D11/0219 , B01D11/0288 , B01D11/0292
摘要： Process for the extraction of substances from at least one silane-modified oxidic or silicatic filler, wherein at least one gas compressed by means of pressure and/or temperature is employed as the extraction agent and the compressed gas is led in the radial direction through the filler in the pressure container and/or the substances extracted from the silane-modified filler are removed from the compressed gas with a suitable sorbent. A device for carrying out the process is furthermore described, wherein this comprises at least one pressure container having at least one internal container, sieve or insert for accommodation of the fillers which is permeable to gas and at least one gas feed and gas removal in the bulk bed of filler, and has a radially designed gas feed or gas removal from the bulk bed of filler.
摘要翻译：用于从至少一种硅烷改性的氧化或硅填料中提取物质的方法，其中使用至少一种通过压力和/或温度压缩的气体作为萃取剂，压缩气体沿径向被引导通过用合适的吸附剂从压缩气体中除去压力容器中的填料和/或从硅烷改性填料中提取的物质。进一步描述了用于执行该方法的装置，其中包括至少一个压力容器，其具有至少一个内部容器，筛子或插入件，用于容纳可渗透气体的填料和至少一种气体进料和气体去除填料填充床，并且具有径向设计的气体进料或从填料填料床排出气体。

8. 发明授权

US06288130B1 Oil-free glycerophospholipid formulations and method for the production thereof 失效
标题翻译：无油甘油磷脂制剂及其制备方法
公开(公告)号：US06288130B1
公开(公告)日：2001-09-11
申请号：US09381527
申请日：1999-09-20
申请人： Jürgen Heidlas , Karl-Heinz Zirzow , Johann Wiesmüller , Martin Ober , Franz Michlbauer , Jürgen Graefe
发明人： Jürgen Heidlas , Karl-Heinz Zirzow , Johann Wiesmüller , Martin Ober , Franz Michlbauer , Jürgen Graefe
IPC分类号： B01F1714
CPC分类号： A61K8/062 , A23J7/00 , A61K8/06 , A61K8/345 , A61K8/553 , A61K2800/52 , A61Q19/00 , C07F9/103
摘要： The invention relates to oil-free glycerophospholipid formulations which contain a homogeneous mixture of glycerophospholipids and an anhydrous, liquid polyol compound such as glycerol in a molar ratio of 1:0.1 to 1. These formulations are produced, eg, by extracting a starting material consisting of an oil-containing glycerophospholipid (mixture) and the polyol component with a compressed hydrocarbon (mixture) in a rectifying column. The oil-free formulation can be obtained from the melt at the bottom of the column in the form of free-flowing powder, which is ideally suited for stabilising oil-in-water emulsions.
摘要翻译：本发明涉及无油甘油磷脂制剂，其含有摩尔比为1:0.1至1的甘油磷脂和无水液体多元醇化合物如甘油的均匀混合物。这些制剂例如通过提取包含的含油甘油磷脂（混合物）和多元醇组分与精馏塔中的压缩烃（混合物）混合。无油配方可以从柱底部的熔体以自由流动的粉末形式获得，其理想地适用于稳定水包油乳液。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式