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    • 5. 发明申请
    • Catheters with suction capability and related methods and systems for obtaining biosamples in vivo
    • 具有抽吸能力的导管和用于在体内获得生物样品的相关方法和系统
    • US20050054994A1
    • 2005-03-10
    • US10827741
    • 2004-04-19
    • Iulian CioantaRichard KleinJacob Lazarovitz
    • Iulian CioantaRichard KleinJacob Lazarovitz
    • A61B10/00A61B10/02A61F2/958A61M25/04A61B17/20A61M1/00
    • A61B10/02A61B10/0045A61B10/007A61M25/04A61M25/1002A61M25/1011
    • Methods, systems, and computer program products for obtaining a sample in vivo and/or treating a subject include positioning an elongated transurethral catheter in the prostatic urethra of a subject, the catheter having a bladder anchoring balloon, at least one biosample entry port disposed axially away from the bladder anchoring balloon, and an axially extending biosample flow channel in fluid communication with the biosample entry port held internally in the catheter. The anchoring balloon is inflated to position the catheter so that the fluid entry port is proximate the prostatic urethra of the subject and prostatic fluid is suctioned from the prostatic urethra into the biosample entry port and into the biosample flow channel. The catheter can include a thermal treatment balloon and/or dilatation balloon and the suctioned sample can be obtained concurrently with, during, or proximate in time to the applied treatment. The catheter can be configured to allow urine to drain therethrough during the treatment/collection of the sample while keeping the urine isolated from the collected prostatic fluid sample.
    • 用于在体内获得样品和/或治疗受试者的方法,系统和计算机程序产品包括将细长的经尿道导管定位在受试者的前列腺尿道中,所述导管具有膀胱锚定球囊,至少一个生物样本入口端口 远离气囊锚定气囊,以及轴向延伸的生物样品流动通道,其与保持在导管内部的生物样品入口端口流体连通。 锚定球囊被充气以定位导管,使得流体进入端口靠近受试者的前列腺尿道,并且前列腺液体从前列腺尿道吸入生物样本入口并进入生物样本流动通道。 导管可以包括热处理球囊和/或扩张球囊,并且抽吸样品可以在施用的治疗时间期间,期间或接近时间获得。 导管可以被配置成允许尿液在样品的处理/收集期间从其中排出,同时保持尿液与收集的前列腺液体样品分离。
    • 7. 发明申请
    • Handle system for deploying a prosthetic implant
    • 用于部署假体植入物的手柄系统
    • US20070156224A1
    • 2007-07-05
    • US11324902
    • 2006-01-04
    • Iulian CioantaCesar RinconBrian WilkinsRance Winkler
    • Iulian CioantaCesar RinconBrian WilkinsRance Winkler
    • A61F2/06
    • A61F2/966A61F2/95A61F2002/9517
    • A handle system of a delivery catheter for the deployment of prosthetic implants includes a first stationary portion, at least one guide rail secured to the first stationary portion and extending generally longitudinally with the handle system, and a generally cylindrical second rotating portion rotably connected to the first stationary portion. A sheath mount is secured to an outer sheath of the delivery catheter, and includes one or more bearing surfaces to engage with at least one of the one or more guide rails. Rotation of the second rotating portion longitudinally displaces the sheath mount by interaction with the sheath mount. Interaction may be by internal thread of the rotating portion and external thread of the sheath mount, or alternately by rotating one or more drive screws by turning the rotating portion, the drive screws interacting with through holes in the sheath mount configured to receive and engage the drive screws.
    • 用于部署假体植入物的输送导管的手柄系统包括第一固定部分,固定到第一固定部分并且与手柄系统大致纵向延伸的至少一个导轨,以及可旋转地连接到第二固定部分的大致圆柱形的第二旋转部分 第一静止部分。 护套安装件被固定到输送导管的外护套上,并且包括一个或多个支承表面,以与一个或多个导轨中的至少一个接合。 第二旋转部分的旋转通过与护套安装件的相互作用纵向地移动护套安装座。 相互作用可以是旋转部分的内螺纹和护套安装件的外螺纹,或者通过转动旋转部分来旋转一个或多个驱动螺钉,驱动螺钉与护套安装件中的通孔相配合,用于接收和接合 驱动螺丝