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    • 5. 发明申请
    • TETRAAZAPORPHYRIN COMPOUNDS
    • 四氮唑啉化合物
    • US20060041120A1
    • 2006-02-23
    • US10922138
    • 2004-08-18
    • Chin-Ti ChenHsiu-Chih Yeh
    • Chin-Ti ChenHsiu-Chih Yeh
    • C07D487/22
    • C07D487/22
    • This invention relates to a method of preparing a compound of formula (I): The method includes reacting one or more compounds of formula (II): in the presence of a base and a halogenating agent. In formulas (I) and (II) above, each A, independently, is aryl or heteroaryl; each n, independently, is 0-3; and each R1, independently, is C1-C10 alkyl, C3-C20 cycloalkyl, C3-C20 heterocycloalkyl, aryl, heteroaryl, halo, cyano, nitro, ORa, NRaRb, SiRaRbRc, COORa, OC(O)Ra, C(O)NRaRb, N(Ra)—C(O)Rb, or SO3Ra; wherein each of Ra, Rb, and Rc, independently, is H, C1-C10 alkyl, C3-C20 cycloalkyl, C3-C20 heterocycloalkyl, aryl, or heteroaryl; thereby producing the compound of formula (I) in a one-pot reaction. This invention also relates to the compounds prepared by the method described above.
    • 本发明涉及一种制备式(I)化合物的方法:该方法包括使一种或多种式(II)化合物在碱和卤化剂存在下反应。 在上述式(I)和(II)中,每个A独立地是芳基或杂芳基; 每个n独立地为0-3; 且每个R 1独立地是C 1 -C 10烷基,C 3 -C 3烷基, 20个环烷基,C 3 -C 20杂环烷基,芳基,杂芳基,卤素,氰基,硝基,OR a, a,b,b,b,b,b,b,b,b,b,c, OC(O)R a a,C(O)NR a R b,N(R a a) C(O)R b,或SO 3 R a a; 其中R a,R b和R c C各自独立地为H,C 1 -C C 1 -C 10烷基,C 3 -C 20环烷基,C 3 -C 20烷基,C 3 -C 20环烷基,C 3 -C 20烷基, 杂环烷基,芳基或杂芳基; 从而在一锅反应中制备式(I)化合物。 本发明还涉及通过上述方法制备的化合物。