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1. 发明专利

IL294152A Method for culturing hematopoietic stem cells 未知
公开(公告)号：IL294152A
公开(公告)日：2022-08-01
申请号：IL29415222
申请日：2022-06-21
申请人： SUMITOMO PHARMA CO LTD , NEXTGEM INC , ATSUSHI NAKANE , HIDETAKA NAGATA , SHIGEHIRO ASANO , MASANORI MIYANISHI , HITOSHI SUDA , YUSUKE SHIODA
发明人： ATSUSHI NAKANE , HIDETAKA NAGATA , SHIGEHIRO ASANO , MASANORI MIYANISHI , HITOSHI SUDA , YUSUKE SHIODA
IPC分类号： A61K35/28 , A61P43/00
摘要： An object of the present invention is to provide a method for culturing one or more hematopoietic stem cells applicable to hematopoietic stem cell transplantation, and a method for producing such one or more hematopoietic stem cells. The method of the present invention for culturing one or more hematopoietic stem cells comprises: culturing a cell population including hematopoietic stem cells in a culture medium containing at least one compound represented by formula (1) or a salt thereof:

2. 发明授权

US08895552B2 Cyclic amide derivative 有权
标题翻译：环状酰胺衍生物
公开(公告)号：US08895552B2
公开(公告)日：2014-11-25
申请号：US13819881
申请日：2011-09-02
申请人： Yoshihiro Horiuchi , Hiroaki Fujiwara , Hitoshi Suda , Izumi Sasaki , Mitsutaka Iwata , Kiyoto Sawamura
发明人： Yoshihiro Horiuchi , Hiroaki Fujiwara , Hitoshi Suda , Izumi Sasaki , Mitsutaka Iwata , Kiyoto Sawamura
IPC分类号： A61K31/535 , C07D277/00
CPC分类号： C07D409/06 , C07C233/74 , C07C235/84 , C07C255/57 , C07C2603/74 , C07D207/32 , C07D207/335 , C07D207/34 , C07D213/50 , C07D213/61 , C07D213/82 , C07D231/12 , C07D233/64 , C07D263/32 , C07D277/20 , C07D277/28 , C07D277/30 , C07D277/56 , C07D295/10 , C07D295/155 , C07D305/08 , C07D307/20 , C07D307/78 , C07D307/81 , C07D309/12 , C07D317/48 , C07D319/18 , C07D333/20 , C07D333/38 , C07D333/58 , C07D409/14
摘要： Provided is a compound represented by formula (1) or a pharmacologically acceptable salt thereof. (In the formula, A is C6-10 arylene, etc.; R1a, R1b and R1c each independently is a hydrogen atom, a halogen atom, a C1-4 alkyl group, a C1-4 alkoxy group, etc.; R2 is an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heteroaryl group, an optionally substituted C7-16 aralkyl group, etc.; m is 0, etc.; n is an integer of 0 to 2.)
摘要翻译：提供由式（1）表示的化合物或其药理学上可接受的盐。（式中，A为C6-10亚芳基等; R1a，R1b和R1c各自独立地为氢原子，卤素原子，C1-4烷基，C1-4烷氧基等; R2为任选取代的C 6-10芳基，任选取代的5至12元单环或多环杂芳基，任选取代的C7-16芳烷基等; m为0等; n为0至 2.）

3. 发明申请

US20130217692A1 CYCLIC AMIDE DERIVATIVE 有权
标题翻译：循环酰胺衍生物
公开(公告)号：US20130217692A1
公开(公告)日：2013-08-22
申请号：US13819881
申请日：2011-09-02
申请人： Yoshihiro Horiuchi , Hiroaki Fujiwara , Hitoshi Suda , Izumi Sasaki , Mitsutaka Iwata , Kiyoto Sawamura
发明人： Yoshihiro Horiuchi , Hiroaki Fujiwara , Hitoshi Suda , Izumi Sasaki , Mitsutaka Iwata , Kiyoto Sawamura
IPC分类号： C07D409/06 , C07D295/155 , C07D277/56 , C07D213/50 , C07C233/74 , C07D333/38
CPC分类号： C07D409/06 , C07C233/74 , C07C235/84 , C07C255/57 , C07C2603/74 , C07D207/32 , C07D207/335 , C07D207/34 , C07D213/50 , C07D213/61 , C07D213/82 , C07D231/12 , C07D233/64 , C07D263/32 , C07D277/20 , C07D277/28 , C07D277/30 , C07D277/56 , C07D295/10 , C07D295/155 , C07D305/08 , C07D307/20 , C07D307/78 , C07D307/81 , C07D309/12 , C07D317/48 , C07D319/18 , C07D333/20 , C07D333/38 , C07D333/58 , C07D409/14
摘要： Provided is a compound represented by formula (1) or a pharmacologically acceptable salt thereof. (In the formula, A is C6-10 arylene, etc.; R1a, R1b and R1c each independently is a hydrogen atom, a halogen atom, a C1-4 alkyl group, a C1-4 alkoxy group, etc.; R2 is an optionally substituted C6-10 aryl group, an optionally substituted 5- to 12-membered monocyclic or polycyclic heteroaryl group, an optionally substituted C7-16 aralkyl group, etc.; m is 0, etc.; n is an integer of 0 to 2.)
摘要翻译：提供由式（1）表示的化合物或其药理学上可接受的盐。（式中，A为C6-10亚芳基等; R1a，R1b和R1c各自独立地为氢原子，卤素原子，C1-4烷基，C1-4烷氧基等; R2为任选取代的C 6-10芳基，任选取代的5至12元单环或多环杂芳基，任选取代的C7-16芳烷基等; m为0等; n为0至 2.）

4. 发明授权

US5699235A Electronic control board assembly including embedded lead frames for electrically connecting the circuit boards of the assembly 失效
标题翻译：电子控制板组件，包括用于电连接组件的电路板的嵌入式引线框架
公开(公告)号：US5699235A
公开(公告)日：1997-12-16
申请号：US507729
申请日：1995-07-26
申请人： Osamu Tsurumiya , Hitoshi Suda , Kazuyuki Iwasaki , Naofumi Inomata
发明人： Osamu Tsurumiya , Hitoshi Suda , Kazuyuki Iwasaki , Naofumi Inomata
IPC分类号： H05K1/18 , H05K1/02 , H05K1/14 , H05K3/20 , H05K3/22 , H05K3/34 , H05K3/36 , H05K5/00 , H05K7/14 , H01R9/09 , H01R23/68
CPC分类号： H05K1/0265 , H05K1/141 , H05K5/0047 , H05K7/1432 , H05K1/144 , H05K2201/0352 , H05K2201/09118 , H05K2201/09754 , H05K2201/09972 , H05K3/202 , H05K3/222 , H05K3/3447 , H05K3/366 , H05K3/368
摘要： An electronic control board assembly has a large-current control unit and a small-current control unit connected to the large-current control unit. The large-current control unit has an insert-molded board with lead frames embedded therein. The insert-molded board has a first component mounting surface and a first component soldering surface facing away therefrom. A first group of components are mounted on the first component mounting surface and have leads extending through the insert-molded board and soldered to the lead frames. The small-current control unit has a printed wiring board which has a second component mounting surface and a second component soldering surface facing away therefrom. A second group of components are mounted on the second component mounting surface and have leads extending through the printed wiring board and soldered to interconnections patterned on the second component soldering surface. The lead frames have ends extending through the printed wiring board and soldered to the interconnections. The first component soldering surface and the second component soldering surface face outwardly.
摘要翻译：电子控制板组件具有连接到大电流控制单元的大电流控制单元和小电流控制单元。大电流控制单元具有插入成型板，其中引入框架嵌入其中。插入成型板具有第一部件安装表面和与其背离的第一部件焊接表面。第一组部件安装在第一部件安装表面上，并且具有延伸穿过嵌入成型板并且焊接到引线框架的引线。小电流控制单元具有印刷电路板，其具有第二部件安装表面和与其背离的第二部件焊接表面。第二组部件安装在第二部件安装表面上，并具有延伸穿过印刷线路板的引线，并焊接到在第二部件焊接表面上图案化的互连。引线框架的端部延伸穿过印刷电路板并焊接到互连。第一部件焊接表面和第二部件焊接表面朝外。

5. 发明授权

US4392539A Instrument panel with a yieldable meter casing 失效
标题翻译：仪表板带有可屈服的仪表外壳
公开(公告)号：US4392539A
公开(公告)日：1983-07-12
申请号：US216941
申请日：1980-12-16
申请人： Takayuki Fujii , Hitoshi Suda
发明人： Takayuki Fujii , Hitoshi Suda
IPC分类号： B60R21/045 , B60R21/04
CPC分类号： B60R21/045
摘要： An instrument panel for vehicles including a base and a trough-shaped meter casing fastened to the base by stays disposed in the meter casing. Each of the stays includes a pair of leg portions which are angularly inclined relative to a principal direction in which severe impacts are likely to occur against the meter casing. When the meter casing is subjected to impacts, the leg portions of the stays give way and buckle such that the meter casing is displaced or yields without being broken or damaged. The impacting force is thus absorbed, and a person in the vehicle who collides with the meter casing is protected from serious injury.
摘要翻译：一种用于车辆的仪表板，包括底座和槽形表壳，通过设置在仪表外壳中的支架固定到基座。每个支柱包括一对腿部，其相对于主要方向成角度地倾斜，在主方向上可能会对仪表壳体产生严重的冲击。当仪表外壳受到冲击时，支柱的脚部会让路和扣环，使得仪表壳体移位或屈服而不被破坏或损坏。冲击力因此被吸收，并且与仪表壳体碰撞的车辆中的人被保护免受严重伤害。

6. 发明授权

US5573079A Electrically operated steering apparatus 失效
标题翻译：电动操舵装置
公开(公告)号：US5573079A
公开(公告)日：1996-11-12
申请号：US473367
申请日：1995-06-07
申请人： Hitoshi Suda , Satoshi Shimada , Susumu Ohta , Junichi Yoshida , Yoshio Kakizaki
发明人： Hitoshi Suda , Satoshi Shimada , Susumu Ohta , Junichi Yoshida , Yoshio Kakizaki
IPC分类号： B62D5/04 , H02K5/22
CPC分类号： B62D5/0406 , B62D5/0427
摘要： An electrically operated steering apparatus for use on a motor vehicle has a cylindrical housing, an axially movable rack shaft disposed in the housing for steering steerable wheels coupled to the rack shaft, and an electric motor disposed in the cylindrical housing around the axially movable shaft for moving the axially movable shaft. A power supply for supplying electric energy to the electric motor is disposed outside of the cylindrical housing. A motor control circuit for generating a motor control signal based on a detected steering torque is disposed in the cylindrical housing. A motor driver circuit is disposed in the cylindrical housing for energizing the electric motor with the electric energy supplied from the power supply based on the motor control signal. An insert-molded board is disposed in the housing and electrically interconnecting the electric motor, the motor control circuit, and the motor driver circuit. The insert-molded board comprises electric conductors and a body of synthetic resin molded around the electric conductors.
摘要翻译：一种用于机动车辆的电动操舵装置具有圆柱形壳体，设置在壳体中的用于转向与齿条轴连接的可转向轮的可轴向移动的齿条轴，以及围绕轴向可移动轴设置在圆柱形壳体中的电动机，移动可轴向移动的轴。用于向电动机供应电能的电源设置在圆筒形壳体的外部。用于基于检测到的转向转矩产生电动机控制信号的电动机控制电路设置在圆筒形壳体中。电动机驱动电路设置在圆筒形壳体中，用于根据电动机控制信号从电源供应的电能来给电动机供电。插入式模板设置在壳体中并使电动马达，马达控制电路和马达驱动电路电连接。插入成型板包括电导体和围绕电导体模制的合成树脂体。

7. 发明授权

US5988311A Electric steering actuator 失效
标题翻译：电动转向执行器
公开(公告)号：US5988311A
公开(公告)日：1999-11-23
申请号：US641373
申请日：1996-04-30
申请人： Takashi Kuribayashi , Kazuhiro Kishimoto , Hirokazu Kitazawa , Yoshitaka Katashima , Yoshio Kakizaki , Hitoshi Suda
发明人： Takashi Kuribayashi , Kazuhiro Kishimoto , Hirokazu Kitazawa , Yoshitaka Katashima , Yoshio Kakizaki , Hitoshi Suda
IPC分类号： B62D5/04 , B62D7/14 , H02K7/06
CPC分类号： B62D5/0448 , B62D5/0427
摘要： In an electric steering actuator comprising an electric motor having a hollow output shaft, a steering shaft passed through the hollow center of the output shaft of the electric motor, and a ball-screw mechanism provided between the output shaft and the steering shaft for converting the rotary movement of the output shaft into a longitudinal movement of the steering shaft. The ball-screw mechanism comprises a threaded section of the steering shaft, and a nut member which threadably engages with the threaded section of the steering shaft via steel balls, and is secured to the output shaft of the electric motor via a serration coupling or the like which achieves an axially free but rotatively fast coupling between the two parts. Thus, the overall axial dimension of the actuator can be reduced, and the step of joining these two parts is significantly simplified in terms of both effort and time while the number of component parts is also reduced. In particular, by installing the ball-screw mechanism in the first casing section in an axially immobile manner, removal of the rotor or the motor assembly is substantially simplified, thereby making the actuator easier to manufacture and service. Also, the motor can be interchanged without affecting the ball-screw mechanism.
摘要翻译：在包括具有中空输出轴的电动机的电动转向致动器中，转向轴穿过电动机的输出轴的中空中心，以及设置在输出轴和转向轴之间的滚珠丝杠机构，用于将输出轴的旋转运动转向转向轴的纵向运动。滚珠丝杠机构包括转向轴的螺纹部分和螺母构件，螺母构件通过钢球与转向轴的螺纹部分螺纹接合，并通过锯齿联轴器或电动马达固定到电动机的输出轴上其实现了两个部件之间的轴向自由但是可旋转地快速的联接。因此，能够减少致动器的总体轴向尺寸，并且在部件数量也减少的同时，在努力和时间方面都显着简化了连接这两个部件的步骤。特别地，通过将滚珠丝杠机构以轴向固定的方式安装在第一壳体部分中，大大简化了转子或马达组件的拆卸，从而使致动器更容易制造和使用。此外，马达可以互换而不影响滚珠丝杆机构。

8. 发明授权

US5957236A Electric steering actuator 失效
标题翻译：电动转向执行器
公开(公告)号：US5957236A
公开(公告)日：1999-09-28
申请号：US641372
申请日：1996-04-30
申请人： Hirokazu Kitazawa , Kazuhiro Kishimoto , Yoshio Kakizaki , Yoshitaka Katashima , Takashi Kuribayashi , Hitoshi Suda
发明人： Hirokazu Kitazawa , Kazuhiro Kishimoto , Yoshio Kakizaki , Yoshitaka Katashima , Takashi Kuribayashi , Hitoshi Suda
IPC分类号： B62D5/04 , B62D7/14 , H02K7/06
CPC分类号： B62D5/0427 , B62D5/0445
摘要： In an electric steering actuator comprising an electric motor having a hollow output shaft, a steering shaft passed through the hollow center of the output shaft of the electric motor, and a ball-screw mechanism provided between the output shaft and the steering shaft for converting the rotary movement of the output shaft into a longitudinal movement of the steering shaft, a rotation preventing mechanism is provided for preventing the rotation of the steering shaft around its axial line. The rotation preventing mechanism comprises a guide pin extending in the casing in parallel with the axial line of the steering shaft, and a fork member engaging the guide pin between two prongs thereof. Because the rotation preventing mechanism can be formed by using a guide pin made of a stock steel or other metallic member, such as a cold finished steel bar, the manufacturing cost can be reduced. Furthermore by using a fork member defining an open slot for engagement with the guide pin, the assembling process is simplified, thereby reducing the manufacturing cost. In particular, by interposing a plastic slider between the pin and the fork member, metallic noises are avoided, and a smooth operation is ensured at a low cost.
摘要翻译：在包括具有中空输出轴的电动机的电动转向致动器中，转向轴穿过电动机的输出轴的中空中心，以及设置在输出轴和转向轴之间的滚珠丝杠机构，用于将输出轴旋转运动到转向轴的纵向运动中，设置有防止转向轴绕其轴线旋转的旋转防止机构。旋转防止机构包括在壳体内平行于转向轴的轴线延伸的引导销和在其两个叉头之间接合引导销的叉构件。由于可以通过使用由坯钢或其他金属构件（例如冷成品钢棒）制成的引导销来形成旋转防止机构，所以可以降低制造成本。此外，通过使用限定开口槽的叉构件与导销接合，组装过程被简化，从而降低制造成本。特别地，通过在销和叉构件之间插入塑料滑动件，避免了金属噪声，并且以低成本确保了平稳的操作。

9. 发明授权

US4372412A Vehicle instrument panel attaching structure 失效
标题翻译：车载仪表板安装结构
公开(公告)号：US4372412A
公开(公告)日：1983-02-08
申请号：US216939
申请日：1980-12-16
申请人： Takayuki Fujii , Hitoshi Suda
发明人： Takayuki Fujii , Hitoshi Suda
IPC分类号： B60K37/00 , B60R21/045 , B62D25/14 , B60K20/08
CPC分类号： B60K37/00 , B60R21/045 , B62D25/147
摘要： A vehicle instrument panel attaching structure wherein the instrument panel is attached to a body frame of the vehicle by means of stays which are disposed in side portions of the instrument panel so as to yieldably connect the instrument panel to the body frame of the vehicle. A predetermined clearance is defined between the instrument panel and the body frame of the vehicle in the assembled condition, so as to accommodate yielding movements of the stays. By virtue of the attaching structure, the instrument panel is yieldingly movable relative to the vehicle body frame when subjected to substantial impacts, thereby protecting a driver or a passenger from injury under unusual conditions such as during a collision of the vehicle.
摘要翻译：一种车辆仪表板安装结构，其中仪表板通过设置在仪表板的侧部中的撑杆附接到车辆的车体框架，以便将仪表板可靠地连接到车辆的车身框架。在组装状态下，在仪表板和车体的框架之间限定了预定的间隙，以适应撑杆的屈服运动。由于安装结构，仪表板在受到实质冲击时相对于车体框架可屈服移动，从而在驾驶员或乘客在诸如车辆碰撞的异常情况下受到伤害。

10. 发明授权

US5303954A Attachment to a ski stick 失效
标题翻译：附件到滑雪棒
公开(公告)号：US5303954A
公开(公告)日：1994-04-19
申请号：US47594
申请日：1993-04-14
申请人： Hitoshi Suda
发明人： Hitoshi Suda
IPC分类号： A63C11/22
CPC分类号： A63C11/224
摘要： An attachment including a timepiece having a function of a stop watch is attached onto the top of a ski stick in order to allow a skier to learn the current time, elapsed time and other time information while skiing, thus more enjoying skiing. By incorporating a thermometer, a barometer, and/or a speed meter in the attachment, the safety of skiing can be heightened.
摘要翻译：包括具有止动表功能的钟表的附件被安装在滑雪板的顶部上，以便滑雪者在滑雪时学习当前时间，经过时间和其他时间信息，从而更多地享受滑雪。通过在附件中安装温度计，气压计和/或速度计，可以提高滑雪的安全性。

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