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    • 7. 发明申请
    • ENZYMATIC PRODUCTION OF ACRYLYL-COA OR ETHYLENE FROM GLYCEROL
    • 丙二醇或乙酸乙烯酯的生产
    • WO2016097289A1
    • 2016-06-23
    • PCT/EP2015/080482
    • 2015-12-18
    • GLOBAL BIOENERGIESSCIENTIST OF FORTUNE S.A.
    • ALLARD, MathieuMARLIERE, Philippe
    • C12P5/02C12N9/08C12N9/02C12P7/62
    • C12P5/026C12N9/0008C12N9/001C12N9/88C12P7/62
    • Described is a method for the production of acrylyl-CoA from glycerol comprising the following steps: (a) the enzymatic conversion of glycerol into 3-hydroxypropionaldehyde; (b) the enzymatic conversion of said 3-hydroxypropionaldehyde into 3-hydroxypropionyl-CoA; and (c) the enzymatic conversion of said 3-hydroxypropionyl-CoA into acrylyl-CoA. Further enzymatic conversion of acrylyl-CoA into other products are disclosed. Further described is a method for the production of ethylene comprising the enzymatic conversion of propionic acid into ethylene. It is described that the enzymatic conversion of propionic acid into ethylene can be achieved by making use of a cytochrome P450 fatty acid decarboxylase or a non-heme iron oxygenase. Further, it is described that said propionic acid can be obtained by the enzymatic conversion of acrylyl-CoA into said propionic acid.
    • 描述了由甘油制备丙烯酰辅酶A的方法,包括以下步骤:(a)将甘油酶促转化为3-羟基丙醛; (b)将所述3-羟基丙醛酶促转化成3-羟基丙酰辅酶A; 和(c)所述3-羟基丙酰辅酶A的酶促转化为丙烯酰辅酶A。 公开了将丙烯酰辅酶A进一步酶促转化成其它产物。 进一步描述了一种生产乙烯的方法,其包括将丙酸酶促转化成乙烯。 描述了丙酸进入乙烯的酶促转化可以通过使用细胞色素P450脂肪酸脱羧酶或非血红素铁加氧酶来实现。 此外,描述了所述丙酸可以通过将丙烯酰辅酶A酶促转化成所述丙酸而获得。