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1. 发明授权

US09079924B2 Method for producing metal compounds 有权
标题翻译：金属化合物的制造方法
公开(公告)号：US09079924B2
公开(公告)日：2015-07-14
申请号：US13504753
申请日：2010-10-29
申请人： Frank Lehmann , Udo Kittelmann
发明人： Frank Lehmann , Udo Kittelmann
IPC分类号： C07F7/22 , C07F7/00
CPC分类号： C07F7/003
摘要： The invention relates to processes for preparing metal(IV) compounds which are suitable especially as catalysts for preparation of polyesters, polyurethanes and polysiloxanes, and to the use of the metal compounds for preparation of polyesters, polyurethanes or polysiloxanes.
摘要翻译：本发明涉及制备金属（Ⅳ）化合物的方法，其特别适用于制备聚酯，聚氨酯和聚硅氧烷的催化剂，以及使用金属化合物制备聚酯，聚氨酯或聚硅氧烷。

2. 发明申请

US20070237497A1 Means for influencing the temperature of flowable media, especially of lubricants found in a lubricant system 有权
标题翻译：用于影响可流动介质温度的方法，特别是在润滑系统中发现的润滑剂的温度
公开(公告)号：US20070237497A1
公开(公告)日：2007-10-11
申请号：US11401481
申请日：2006-04-11
申请人： Frank Lehmann
发明人： Frank Lehmann
IPC分类号： H05B3/60
CPC分类号： H05B3/82 , F01M5/001 , H05B3/42 , H05B2203/021
摘要： A means for influencing the temperature of flowable media, especially of lubricants found in a lubricant system, having a line through which the medium flows and at least one element (11) which is assigned to the line section (1, 5) for influencing the temperature and which can be activated by supplying energy, characterized in that at least one element (11) is located within the line section (1, 5) in the flow path of the medium and that the wall of the line section (1, 5) has a connecting means (9) for supplying energy to at least one element (11) located in the line section (1, 5).
摘要翻译：一种用于影响可流动介质温度的方法，特别是在润滑系统中发现的润滑剂的温度，其具有介质流过的管线和分配给管线部分（5,5）的至少一个元件（11），用于影响温度，并且其可以通过供应能量来激活，其特征在于，至少一个元件（11）位于所述介质的流动路径中的所述管线部分（5,5）内，并且所述管线部分（5,5））具有用于向位于线路区段（1,5）中的至少一个元件（11）供应能量的连接装置（9）。

3. 发明申请

US20090073280A1 Digital Line Scan Camera 有权
标题翻译：数字线扫描相机
公开(公告)号：US20090073280A1
公开(公告)日：2009-03-19
申请号：US12211949
申请日：2008-09-17
申请人： Anko BORNER , Andreas ECKARDT , Frank LEHMANN
发明人： Anko BORNER , Andreas ECKARDT , Frank LEHMANN
IPC分类号： H04N5/228 , H04N5/225
CPC分类号： G01C11/02 , H04N5/23254 , H04N5/3692 , H04N2101/00 , H04N2201/3253
摘要： Disclosed is a digital line scan camera, having at least at least one focal plane, on which at least one linear photosensitive sensor is arranged, an objective lens, and a location measurement system. The location measurement system is used to determine six external location parameters, where the location system measurement comprises a satellite-supported position determination device and an inertial navigation measurement unit. The line scan camera includes at least on two-dimensional photosensitive sensor, which is synchronously driven with the linear sensor. At least one displacement vector ({right arrow over (x)}) is calculated from the data of the minimum of one two-dimensional photosensitive sensor, and where the displacement vector ({right arrow over (x)}) is used to correct the date of the inertial measurement unit.
摘要翻译：公开了一种数字线扫描照相机，其具有至少一个焦平面，至少一个线性光敏传感器布置在该平面上，物镜和位置测量系统。位置测量系统用于确定六个外部位置参数，其中定位系统测量包括卫星支持位置确定装置和惯性导航测量单元。行扫描照相机至少包括与线性传感器同步驱动的二维光敏传感器。根据一个二维感光传感器的最小值的数据计算至少一个位移矢量（{（x）}上的右箭头}），并且使用位移矢量（{右箭头（x）}）来校正惯性测量单位的日期。

4. 发明授权

US07019088B1 Hardenable materials which contain uretdione groups, method for the production and processing thereof, and their utilization 有权
标题翻译：含有脲二酮基团的可硬化材料，其生产和加工方法及其应用
公开(公告)号：US07019088B1
公开(公告)日：2006-03-28
申请号：US09856474
申请日：1999-12-03
申请人： Frank Lehmann , Michaela Gedan-Smolka , Dieter Lehmann
发明人： Frank Lehmann , Michaela Gedan-Smolka , Dieter Lehmann
IPC分类号： C08G18/22 , C08G18/40 , C08G18/70
CPC分类号： C08G18/798 , Y10T428/31551
摘要： The invention is used in the fields of chemistry and relates to hardenable materials which can be used for producing lacquers. The aim of the invention is to provide materials which harden at low temperatures in the same amount of time as the others. This is achieved by using hardenable materials containing uretdione groups and containing (A) a binding agent constituent, whereby this component either (A1) does not contain carboxyl groups, or (A2) the concentration of carboxyl groups is less than that of the catalyst (C) or (A3) in the case of a high level of concentration, a quantity of a reactive agent is added. The hardenable materials also contain (B) a polyaddition compound which comprises uretdione groups, and (C) at least one Lewis acid catalyst. The aim of the invention is also achieved using a method for producing materials of this type in which the starting materials are homogenized in a solution and/or in a melt, the solution and/or melt is then rapidly cooled, and the subsequent processing is carried out afterwards to effect a complete cross-linking.
摘要翻译：本发明用于化学领域，涉及可用于生产漆的可硬化材料。本发明的目的是提供在低温下与其它时间相同的时间硬化的材料。这是通过使用含有脲二酮基团的可硬化材料并含有（A）结合剂成分来实现的，其中该组分（A1）不含羧基，或（A2）羧基的浓度小于催化剂的浓度 C）或（A3）在高浓度的情况下，添加反应剂的量。可硬化材料还含有（B）包含脲二酮基团的加聚化合物，和（C）至少一种路易斯酸催化剂。本发明的目的还通过使用这种类型的材料的方法实现，其中起始材料在溶液和/或熔体中均化，然后将溶液和/或熔体快速冷却，随后的处理是之后进行完成交叉。

5. 发明授权

US06708665B1 Fluid cooling device 有权
标题翻译：流体冷却装置
公开(公告)号：US06708665B1
公开(公告)日：2004-03-23
申请号：US10070364
申请日：2002-03-06
申请人： Frank Lehmann
发明人： Frank Lehmann
IPC分类号： F28F300
CPC分类号： F16H57/0413 , F01M1/10 , F01M11/03 , F01M2011/033 , F01M2011/035 , F16H57/0415
摘要： A fluid cooling device has a cooler, filter and pump combined in a building unit. Fluid conveyed by the pump can be filtered in a fluid circuit by the filter and can be cooled in the circuit by the cooler. The filter is provided with at least one filter element that can be exchanged when the filter is clogged. A controllable unit is provided in the fluid circuit for exchanging the filter element. The filter can be separated from the pump by the controllable unit in such a way that the cooler is still supplied with the fluid to be cooled. The filter element can be exchanged without entailing further difficulties, even when the downstream supply of lubricating oil is not stopped.
摘要翻译：流体冷却装置具有组合在建筑单元中的冷却器，过滤器和泵。由泵输送的流体可以通过过滤器在流体回路中过滤，并且可以通过冷却器在回路中冷却。过滤器设置有至少一个过滤器元件，当过滤器堵塞时可以更换过滤元件。在流体回路中提供可控单元以更换过滤元件。过滤器可以通过可控单元与泵分离，使得冷却器仍然被供应待冷却的流体。即使不停止润滑油的下游供给，也可以更换过滤元件而不会产生进一步的困难。

6. 发明授权

US07351829B2 Compounds on the basis of 2- and 4-chromenylidene-merocyanines respectively, and their use 有权
标题翻译：分别以2-和4-亚氯烯基 - 部花青为基础的化合物及其用途
公开(公告)号：US07351829B2
公开(公告)日：2008-04-01
申请号：US10190371
申请日：2002-07-03
申请人： Peter Czerney , Wilhelm Frank , Matthias Wenzel , Frank Lehmann
发明人： Peter Czerney , Wilhelm Frank , Matthias Wenzel , Frank Lehmann
IPC分类号： C07D239/62 , C07D239/66 , C09B57/02
CPC分类号： C07D405/06 , C07D405/14 , C07D491/04 , C07F9/65586 , C09B23/0066 , C09B23/105 , C09B23/107
摘要： The invention relates to compounds based on merocyanines with the general formulas I and/or II, where n=0 or an integer from 1 to 3, X=O or S and the residues R1 to R12 are the same or different and signify in particular hydrogen or various organic residues, without or with functional groups, and R2 incorporates an amine function. The compounds in accordance with the invention are suitable as fluorescent dyes (fluorophores) for used in optical determination and demonstration methods, in particular those employing fluorescence, for example in medicine, pharmacology and the biological, materials and environmental sciences. They are characterized by high photostability and long storage life, and exhibit a high fluorescence quantum yield. Excitation causing them to emit light can be achieved in a simple manner, by white-light sources or by laser irradiation in the UV, visible or NIR spectral region.
摘要翻译：本发明涉及基于具有通式I和/或II的部花青的化合物，其中n = 0或1至3的整数，X = O或S，残基R 1至R“ SUP> 12相同或不同，特别表示没有或具有官能团的氢或各种有机残基，并且R 2包含胺官能团。根据本发明的化合物适用于用于光学测定和显示方法的荧光染料（荧光团），特别是使用荧光的那些，例如在医学，药理学和生物，材料和环境科学中。它们的特征在于高的光稳定性和长的储存寿命，并表现出高的荧光量子产率。可以通过白光源或通过在UV，可见光或NIR光谱区域中的激光照射以简单的方式实现引起它们发光的激发。

7. 发明申请

US20070128659A1 HYDROPHILIC LABELS FOR BIOMOLECULES 有权
标题翻译：生物分子水合物标签
公开(公告)号：US20070128659A1
公开(公告)日：2007-06-07
申请号：US11566699
申请日：2006-12-05
申请人： Peter Czerney , Wilhelm Frank , Frank Lehmann , Bernd Schweder , Matthias Wenzel
发明人： Peter Czerney , Wilhelm Frank , Frank Lehmann , Bernd Schweder , Matthias Wenzel
IPC分类号： G01N33/53 , C07D403/02
CPC分类号： G01N33/582 , G01N33/533
摘要： Compounds, compositions, and methods for optical, including fluorescence optical, determinations useful in labelling biomolecules such as protein and deoxyribonucleic acid for their detection and quantitation. The compounds are diasteromeric cyanines with high hydrophilicity and other desirable properties.
摘要翻译：用于光学的化合物，组合物和方法，包括用于标记生物分子如蛋白质和脱氧核糖核酸的荧光光学测定用于其检测和定量。该化合物是具有高亲水性和其它所需性质的非对映体花青。

8. 发明授权

US06750346B2 Stable near-infrared (NIR) marker dyes based on benzopyrylium-polymethines 有权
标题翻译：基于苯并吡喃 - 聚甲基的稳定近红外（NIR）标记染料
公开(公告)号：US06750346B2
公开(公告)日：2004-06-15
申请号：US10031741
申请日：2002-01-22
申请人： Peter Czerney , Frank Lehmann , Bernd Schweder , Matthias Wenzel
发明人： Peter Czerney , Frank Lehmann , Bernd Schweder , Matthias Wenzel
IPC分类号： C07D51300
CPC分类号： G01N33/582 , C09B23/0066 , C09B23/02 , C12Q2563/107
摘要： The disclosure is directed to so-called laser-compatible NIR marker dyes based on polymethines for use in optical, in particular, fluorescence optical determination and detection methods, for example, in the fields of medicine, pharmaceutics and in the areas of life science, materials science and environmental science. The disclosure further discusses the aim of the invention which was to create NIR marker dyes based on polymethine which have a high degree of photostability and stability in storage as well as a high fluorescent yield and which can be excited to fluorescence in the easiest possible manner by means of laser radiation in the visible or NIR spectral range, particularly with light of an argon, helium/neon, or diode laser. Dyes based on polymethine of general formula (I) are used.
摘要翻译：本公开涉及基于用于光学的聚甲基化的所谓的激光兼容NIR标记染料，特别是荧光光学测定和检测方法，例如在医学，制药领域以及生命科学领域，材料科学与环境科学。本公开进一步讨论了本发明的目的，其是基于聚甲基化产生具有高度光稳定性和储存稳定性以及高荧光产率的基于聚甲炔的NIR标记染料，并且可以以最简单可能的方式将其激发至荧光在可见光或近红外光谱范围内的激光辐射的手段，特别是在氩，氦/氖或二极管激光的光下。使用基于通式（I）的聚甲炔的染料。

9. 发明申请

US20150232457A1 CRYSTALLINE FORMS OF AFATINIB DI-MALEATE 审中-公开
标题翻译： AFATINIB DI-MALEATE的结晶形式
公开(公告)号：US20150232457A1
公开(公告)日：2015-08-20
申请号：US14349217
申请日：2012-04-25
申请人： Anja Bruns , Simone Eichner , Frank Lehmann , Wolfgang Albrecht , Annemarie Maier
发明人： Anja Bruns , Simone Eichner , Frank Lehmann , Wolfgang Albrecht , Annemarie Maier
IPC分类号： C07D405/12
CPC分类号： C07D405/12 , C07D407/12
摘要： Crystalline forms of Afatinib di-maleate are described in the present application and processes for their preparation. The present invention also includes pharmaceutical compositions of such crystalline forms of Afatinib di-maleate, methods of their preparation and the use thereof hi the treatment of a patient in need thereof. The present invention also describes preparing Afatinib free base and salts of Afatinib, other than Afatibin di-maleate, and solid forms thereof.
摘要翻译：在本申请中描述了阿拉美文二马来酸盐的结晶形式及其制备方法。本发明还包括这种阿马替尼二马来酸盐的结晶形式的药物组合物，其制备方法及其用途在治疗有需要的患者时。本发明还描述了制备除了阿马替双二马来酸酯之外的阿拉美糖素游离碱和阿拉伯胶的盐及其固体形式。

10. 发明授权

US07563907B2 Compounds based on polymethines 有权
标题翻译：基于聚甲基化合物
公开(公告)号：US07563907B2
公开(公告)日：2009-07-21
申请号：US10846789
申请日：2004-05-14
申请人： Peter Czerney , Matthias Wenzel , Bernd Schweder , Frank Lehmann
发明人： Peter Czerney , Matthias Wenzel , Bernd Schweder , Frank Lehmann
IPC分类号： C07D405/06
CPC分类号： C09B23/107 , C09B57/02
摘要： The invention relates to fluorescent dyes (fluorophores) based on polymethines for use in optical measurement and detection procedures, in particular those employing fluorescence, for example in medicine, in pharmacology and in the biological, materials and environmental sciences. The objective was to create fluorophores based on polymethines that have a large Stokes shift, high photostability, long storage life and a high fluorescent quantum yield, and that can be excited in the simplest possible manner by white-light sources or laser radiation in the UV, visible or NIR spectral region. According to the invention dyes on the basis of polymethines having the general formulas I, II or III are employed.
摘要翻译：本发明涉及基于用于光学测量和检测程序的聚甲基化的荧光染料（荧光团），特别是使用荧光的那些，例如在医学，药理学以及生物，材料和环境科学中。目的是基于具有大的斯托克斯位移，高光稳定性，长存储寿命和高荧光量子产率的聚甲基化产生荧光团，并且可以以最简单的方式通过白光源或UV中的激光辐射来激发荧光团，可见光或近红外光谱区。根据本发明，采用基于具有通式I，II或III的聚甲基的染料。

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