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1. 外观设计

USD827492S1 Ski for an all-terrain vehicle 有权
公开(公告)号：USD827492S1
公开(公告)日：2018-09-04
申请号：US29597319
申请日：2017-03-16
申请人： Mario Lessard , Denis Lessard
设计人： Mario Lessard , Denis Lessard

2. 发明授权

US08723945B2 Optical inspection apparatus and method 有权
标题翻译：光学检测装置及方法
公开(公告)号：US08723945B2
公开(公告)日：2014-05-13
申请号：US13183750
申请日：2011-07-15
申请人： Denis Lessard
发明人： Denis Lessard
IPC分类号： G01B11/245
CPC分类号： G01B11/245
摘要： An optical apparatus and method for simultaneously scanning the profile of at least two adjacent surfaces of an article such as a wooden board moving along a travel path axis passing through an inspection area located at a central plane transverse to the travel path axis, involve first and second scanning zones sufficiently spaced one with another along the travel path axis to substantially prevent mutual scanning interference between the profile sensors used, while providing a compact arrangement of profile sensors. For so doing, one the first sensing field and the first laser beam of the first profile sensor is crossing the central plane toward the other one of the first sensing field and the first laser beam, and one the second sensing field and the second laser beam of the second profile sensor is crossing the central plane toward the other one of the second sensing field and the second laser beam.
摘要翻译：一种用于同时扫描诸如木板的物品的至少两个相邻表面的轮廓的光学装置和方法，所述物体沿着行进路径轴线移动，该行进路径轴线穿过位于横向于行进路径轴线的中心平面的检查区域，涉及第一和第二扫描区域沿着行进路径轴线彼此充分地间隔开，以基本上防止所使用的轮廓传感器之间的相互扫描干涉，同时提供轮廓传感器的紧凑布置。这样做，第一轮廓传感器的第一感测场和第一激光束中的一个与中心平面朝向第一感测场和第一激光束中的另一个相交，第二感测场和第二激光束第二轮廓传感器的中心平面朝向第二感测场和第二激光束中的另一个。

3. 发明申请

US20120274758A1 OPTICAL INSPECTION APPARATUS AND METHOD 有权
标题翻译：光学检测装置和方法
公开(公告)号：US20120274758A1
公开(公告)日：2012-11-01
申请号：US13183750
申请日：2011-07-15
申请人： Denis Lessard
发明人： Denis Lessard
IPC分类号： H04N7/18 , G01B11/24
CPC分类号： G01B11/245
摘要： An optical apparatus and method for simultaneously scanning the profile of at least two adjacent surfaces of an article such as a wooden board moving along a travel path axis passing through an inspection area located at a central plane transverse to the travel path axis, involve first and second scanning zones sufficiently spaced one with another along the travel path axis to substantially prevent mutual scanning interference between the profile sensors used, while providing a compact arrangement of profile sensors. For so doing, one the first sensing field and the first laser beam of the first profile sensor is crossing the central plane toward the other one of the first sensing field and the first laser beam, and one the second sensing field and the second laser beam of the second profile sensor is crossing the central plane toward the other one of the second sensing field and the second laser beam.
摘要翻译：一种用于同时扫描诸如木板的物品的至少两个相邻表面的轮廓的光学装置和方法，所述物体沿着行进路径轴线移动，该行进路径轴线穿过位于横向于行进路径轴线的中心平面的检查区域，涉及第一和第二扫描区域沿着行进路径轴线彼此充分地间隔开，以基本上防止所使用的轮廓传感器之间的相互扫描干涉，同时提供轮廓传感器的紧凑布置。这样做，第一轮廓传感器的第一感测场和第一激光束中的一个与中心平面朝向第一感测场和第一激光束中的另一个相交，第二感测场和第二激光束第二轮廓传感器的中心平面朝向第二感测场和第二激光束中的另一个。

4. 发明申请

US20060054807A1 Ionization source for mass spectrometer 有权
标题翻译：质谱仪电离源
公开(公告)号：US20060054807A1
公开(公告)日：2006-03-16
申请号：US11133896
申请日：2005-05-20
申请人： Pierre Picard , Denis Lessard , Andre L'Heureux , Jean Lacoursiere , Philippe Nobert , Sylvain Letarte , Alexandre Vallieres , Robert Tiveron , Real Paquin
发明人： Pierre Picard , Denis Lessard , Andre L'Heureux , Jean Lacoursiere , Philippe Nobert , Sylvain Letarte , Alexandre Vallieres , Robert Tiveron , Real Paquin
IPC分类号： H01J49/10 , H01J49/04
CPC分类号： H01J49/0463 , H01J49/049 , H01J49/168
摘要： An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.
摘要翻译：提供了用于质谱仪再生离子样品的装置和方法。源样品被加载在被激光束加热的支撑件上，而不离子地解吸样品。解吸的样品由载气流通过传输管承载，其输出通过电晕放电或光电离被离子化。所获得的电离样品可以在质谱仪中进行分析或者用于任何其它合适的目的。

5. 发明授权

US08049779B2 Camera calibrating apparatus and method 有权
标题翻译：相机校准装置及方法
公开(公告)号：US08049779B2
公开(公告)日：2011-11-01
申请号：US12195753
申请日：2008-08-21
申请人： Pierre Poulin , Jean-Luc Lessard , Denis Lessard
发明人： Pierre Poulin , Jean-Luc Lessard , Denis Lessard
IPC分类号： H04N17/02
CPC分类号： G01B11/2504 , G06T7/521
摘要： A camera calibrating apparatus uses a calibration target in combination with a laser source generating a laser beam defining a calibration plane and intersecting the camera field of view to define an object imaging area. The calibration target includes a frame defining a coplanar arrangement of more than five reference points having known position coordinates within an object reference system. The frame is disposed in a camera calibration position wherein the coplanar arrangement of reference points is substantially parallel to the calibration plane. The target includes an arrangement of light reflecting members protruding from the arrangement of reference points in a direction substantially perpendicular thereto so as to extend within the object imaging area, to allow the camera to capture an image formed by illuminated portions of the light reflecting members. The apparatus further includes image processor means programmed on the basis a calibrated camera model to associate any position coordinates in the object reference system with corresponding position coordinates in an image reference system.
摘要翻译：相机校准装置使用校准目标与激光源组合，产生定义校准平面并与照相机视场相交的激光束以限定对象成像区域。校准目标包括限定在对象参考系统内具有已知位置坐标的多于五个参考点的共面布置的框架。框架设置在相机校准位置，其中参考点的共面布置基本上平行于校准平面。目标包括从参考点的布置在基本上垂直于其的方向突出的光反射构件的布置，以便在物体成像区域内延伸，以允许照相机捕获由光反射构件的照明部分形成的图像。该装置还包括基于校准的相机模型编程的图像处理器装置，以将对象参考系统中的任何位置坐标与图像参考系统中的相应位置坐标相关联。

6. 发明授权

US07321116B2 Ionization source for mass spectrometer 有权
标题翻译：质谱仪电离源
公开(公告)号：US07321116B2
公开(公告)日：2008-01-22
申请号：US11133896
申请日：2005-05-20
申请人： Pierre Picard , Denis Lessard , André L'Heureux , Jean Lacoursiere , Philippe Nobert , Sylvain Letarte , Alexandre Vallieres , Robert Tiveron , Réal Paquin
发明人： Pierre Picard , Denis Lessard , André L'Heureux , Jean Lacoursiere , Philippe Nobert , Sylvain Letarte , Alexandre Vallieres , Robert Tiveron , Réal Paquin
IPC分类号： H01J49/04
CPC分类号： H01J49/0463 , H01J49/049 , H01J49/168
摘要： An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.
摘要翻译：提供了用于质谱仪再生离子样品的装置和方法。源样品被加载在被激光束加热的支撑件上，而不离子地解吸样品。解吸的样品由载气流通过传输管承载，其输出通过电晕放电或光电离被离子化。所获得的电离样品可以在质谱仪中进行分析或者用于任何其它合适的目的。

7. 发明授权

US06506414B2 Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof 失效
标题翻译：鲨鱼软骨的低分子量组分，其制备方法及其治疗用途
公开(公告)号：US06506414B2
公开(公告)日：2003-01-14
申请号：US09751111
申请日：2000-12-29
申请人： Eric Dupont , Yves Lachance , Denis Lessard , Serge Auger
发明人： Eric Dupont , Yves Lachance , Denis Lessard , Serge Auger
IPC分类号： A61K3512
CPC分类号： A61K35/60
摘要： This invention relates to a process by which organic solvent-containing solutions are used in lieu of pure water for the preparation of cartilage extracts and fractions thereof. Different organic solvents have been tested for the preparation of extracts containing biologically active components possessing at least an activity against a matrix metalloprotease (anti-MMP). This invention also relates to a process by which a total liquid extract of shark cartilage composed of molecules having molecular weights less than about 500kDa (0-500 fraction) is purified into two well separated fractions composed of molecules having molecular weights less than about 1 kDa (0-1 fraction) and between about 1 to 500 kDa (1-500 fraction). In order to prevent the formation of aggregates, to improve the dissolution and the stability of active components, sucrose or other stabilizing agents can be added. The 0-500 fraction, the 0-1 fraction and the 1-500 fraction as well as their equivalents containing 1% w/v sucrose possess have anti-MMP and anti-tumor activities. The invention also provides a component which has at least anti-MMP and anti-tumor activities, and which has a mass of 244 amu (atomic mass unit). The use of the above extracts, derived fractions or components for inhibiting MMP enzyme, neovascularization and/or metastase formation is also described.
摘要翻译：本发明涉及使用含有机溶剂的溶液代替纯水来制备软骨提取物及其级分的方法。已经测试了不同的有机溶剂来制备含有至少对基质金属蛋白酶（抗-MMP）具有活性的生物活性组分的提取物。本发明还涉及由具有小于约500kDa（0-500级分）的分子组成的鲨鱼软骨的总液体提取物被纯化成由分子量小于约1kDa的分子组成的两个良好分离的级分（0-1分数）和约1至500kDa（1-500分数）之间。为了防止聚集体的形成，为了改善活性组分的溶解和稳定性，可以加入蔗糖或其它稳定剂。 0-500级分，0-1级分和1-500级分以及其含有1％w / v蔗糖的当量具有抗MMP和抗肿瘤活性。本发明还提供了具有至少抗MMP和抗肿瘤活性，并且质量为244amu（原子质量单位）的组分。还描述了上述提取物，衍生级分或组分用于抑制MMP酶，新血管形成和/或转移形成的用途。

8. 发明授权

US07429999B2 Camera calibrating apparatus and method 失效
标题翻译：相机校准装置及方法
公开(公告)号：US07429999B2
公开(公告)日：2008-09-30
申请号：US11133243
申请日：2005-05-20
申请人： Pierre Poulin , Jean-Luc Lessard , Denis Lessard
发明人： Pierre Poulin , Jean-Luc Lessard , Denis Lessard
IPC分类号： H04N17/02
CPC分类号： G01B11/2504 , G06T7/521
摘要： A camera calibrating apparatus uses a calibration target in combination with a laser source generating a laser beam defining a calibration plane and intersecting the camera field of view to define an object imaging area. The calibration target includes a frame defining a coplanar arrangement of reference points having known position coordinates within an object reference system. The frame is disposed in a camera calibration position wherein the coplanar arrangement of reference points is substantially parallel to the calibration plane. The target includes an arrangement of light reflecting members protruding from the arrangement of reference points in a direction substantially perpendicular thereto, each said member having a light reflecting surface substantially parallel to said direction so as to extend within the object imaging area, to allow the camera to capture an image formed by illuminated portions of the light reflecting members. The apparatus further includes image processor means programmed on the basis a calibrated camera model to associate any position coordinates in the object reference system with corresponding position coordinates in an image reference system.
摘要翻译：相机校准装置使用校准目标与激光源组合，产生定义校准平面并与照相机视场相交的激光束以限定对象成像区域。校准目标包括限定在对象参考系统内具有已知位置坐标的参考点的共面排列的框架。框架设置在相机校准位置，其中参考点的共面布置基本上平行于校准平面。目标包括从基准点的布置在基本上垂直于其的方向突出的光反射构件的布置，每个所述构件具有基本上平行于所述方向的光反射表面，以便在物体成像区域内延伸，以允许相机以捕获由光反射部件的照明部分形成的图像。该装置还包括基于校准的相机模型编程的图像处理器装置，以将对象参考系统中的任何位置坐标与图像参考系统中的相应位置坐标相关联。

9. 发明申请

US20050270375A1 Camera calibrating apparatus and method 失效
标题翻译：相机校准装置及方法
公开(公告)号：US20050270375A1
公开(公告)日：2005-12-08
申请号：US11133243
申请日：2005-05-20
申请人： Pierre Poulin , Jean-Luc Lessard , Denis Lessard
发明人： Pierre Poulin , Jean-Luc Lessard , Denis Lessard
IPC分类号： G01B11/25 , H04N17/02
CPC分类号： G01B11/2504 , G06T7/521
摘要： A camera calibrating apparatus uses a calibration target in combination with a laser source generating a laser beam defining a calibration plane and intersecting the camera field of view to define an object imaging area. The calibration target includes a frame defining a coplanar arrangement of reference points having known position coordinates within an object reference system. The frame is disposed in a camera calibration position wherein the coplanar arrangement of reference points is substantially parallel to the calibration plane. The target includes an arrangement of light reflecting members protruding from the arrangement of reference points in a direction substantially perpendicular thereto so as to extend within the object imaging area, to allow the camera to capture an image formed by illuminated portions of the light reflecting members. The apparatus further includes image processor means programmed on the basis a calibrated camera model to associate any position coordinates in the object reference system with corresponding position coordinates in an image reference system.
摘要翻译：相机校准装置使用校准目标与激光源组合，产生定义校准平面并与照相机视场相交的激光束以限定对象成像区域。校准目标包括限定在对象参考系统内具有已知位置坐标的参考点的共面排列的框架。框架设置在相机校准位置，其中参考点的共面布置基本上平行于校准平面。目标包括从参考点的布置在基本上垂直于其的方向突出的光反射构件的布置，以便在物体成像区域内延伸，以允许照相机捕获由光反射构件的照明部分形成的图像。该装置还包括基于校准的相机模型编程的图像处理器装置，以将对象参考系统中的任何位置坐标与图像参考系统中的相应位置坐标相关联。

10. 发明授权

US07582863B2 Sample support for desorption 有权
标题翻译：样品支持解吸
公开(公告)号：US07582863B2
公开(公告)日：2009-09-01
申请号：US11946710
申请日：2007-11-28
申请人： Pierre Picard , Andre L'heureux , Jean Lacoursiere , Philippe Nobert , Sylvain Letarte , Alexandre Vallieres , Réal Paquin , Denis Lessard
发明人： Pierre Picard , Andre L'heureux , Jean Lacoursiere , Philippe Nobert , Sylvain Letarte , Alexandre Vallieres , Réal Paquin , Denis Lessard
IPC分类号： H01J49/04
CPC分类号： H01J49/0463 , H01J49/049 , H01J49/168
摘要： An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.
摘要翻译：提供了用于质谱仪再生离子样品的装置和方法。源样品被加载在被激光束加热的支撑件上，而不离子地解吸样品。解吸的样品由载气流通过传输管承载，其输出通过电晕放电或光电离被离子化。所获得的电离样品可以在质谱仪中进行分析或者用于任何其它合适的目的。

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