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    • 1. 发明申请
    • METHOD OF USING AJOENE AS ALCOHOL DEHYDROGENASE INHIBITOR, COMPOSITION FOR REMOVING HANGOVER COMPRISING AJOENE AND METHOD OF PREPARING THE SAME
    • 使用AJOENE作为酒精脱氢抑制剂的方法,用于除去包含AJOENE的反应物的组合物及其制备方法
    • US20080102142A1
    • 2008-05-01
    • US11970261
    • 2008-01-07
    • Sang Hyun PAEKChristopher KO
    • Sang Hyun PAEKChristopher KO
    • A61K36/8962A61P43/00
    • A61K31/105A61K31/145A61K36/8962
    • The present invention provides a composition for removing a hangover. In particular, the present invention discloses a method of using ajoene as an alcohol dehydrogenase inhibitor based on the fact that ajoene strongly inhibits alcohol dehydrogenase (ADH) activity. A composition for removing a hangover comprising ajoene suppresses the over-production of acetaldehyde during alcohol metabolism to maintain acetaldehyde concentration in blood at a normal level that can be degraded in the body and eliminated therefrom through normal metabolic and secretory pathways to thereby prevent the hangover after consumption of alcohol, and a method of preparing the same, are also provided. The present invention also provides a novel use of ajoene, which is a natural substance obtained by purification of garlic, and a composition for removing a hangover comprising ajoene, which is harmless to the body and strongly inhibits ADH activity, thereby showing very excellent relieving effect on the hangover.
    • 本发明提供一种去除宿醉的组合物。 特别地,本发明公开了一种基于阿魏烯强烈抑制醇脱氢酶(ADH)活性的事实,使用邻苯二酚作为醇脱氢酶抑制剂的方法。 一种用于去除宿醉的组合物,其包含乙醇代谢过程中乙醛过量产生,以维持血液中的乙醛浓度达到正常水平,其能够通过正常代谢和分泌途径在体内降解,从而通过正常的代谢和分泌途径从而脱除,从而防止宿醉后的宿醉 还提供了饮用酒精及其制备方法。 本发明还提供了一种通过纯化大蒜获得的天然物质和一种用于除去宿醉的组合物的新颖用途,所述宿醉包括对人体无害的ADH活性,从而显示非常优异的缓解作用 在宿醉
    • 2. 发明申请
    • Method of using ajoene as alcohol dehydrogenase inhibitor, composition for removing hangover comprising ajoene and method of preparing the same
    • 使用邻苯二酚作为醇脱氢酶抑制剂的方法,除去宿醉的组合物及其制备方法
    • US20070031520A1
    • 2007-02-08
    • US11498563
    • 2006-08-03
    • Sang PaekChristopher Ko
    • Sang PaekChristopher Ko
    • A61K36/8962A61K31/11
    • A61K31/105A61K31/145A61K36/8962
    • The present invention provides a composition for removing a hangover. In particular, the present invention discloses a method of using ajoene as an alcohol dehydrogenase inhibitor based on the fact that ajoene strongly inhibits alcohol dehydrogenase (ADH) activity. A composition for removing a hangover comprising ajoene suppresses the over-production of acetaldehyde during alcohol metabolism to maintain acetaldehyde concentration in blood at a normal level that can be degraded in the body and eliminated therefrom through normal metabolic and secretory pathways to thereby prevent the hangover after consumption of alcohol, and a method of preparing the same, are also provided. The present invention also provides a novel use of ajoene, which is a natural substance obtained by purification of garlic, and a composition for removing a hangover comprising ajoene, which is harmless to the body and strongly inhibits ADH activity, thereby showing very excellent relieving effect on the hangover.
    • 本发明提供一种去除宿醉的组合物。 特别地,本发明公开了一种基于阿魏烯强烈抑制醇脱氢酶(ADH)活性的事实,使用邻苯二酚作为醇脱氢酶抑制剂的方法。 一种用于去除宿醉的组合物,其包含乙醇代谢过程中乙醛过量产生,以维持血液中的乙醛浓度达到正常水平,其能够通过正常代谢和分泌途径在体内降解,从而通过正常的代谢和分泌途径从而脱除,从而防止宿醉后的宿醉 还提供了饮用酒精及其制备方法。 本发明还提供了一种通过纯化大蒜获得的天然物质和一种用于除去宿醉的组合物的新颖用途,所述宿醉包括对人体无害的ADH活性,从而显示非常优异的缓解作用 在宿醉