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1. 发明申请

US20060035247A1 Biochip with radio frequency identification tag attached thereto, hybridization system, and hybridization management method 审中-公开
标题翻译：带有射频识别标签的生物芯片，杂交系统和杂交管理方法
公开(公告)号：US20060035247A1
公开(公告)日：2006-02-16
申请号：US11121481
申请日：2005-05-04
申请人： Christopher Ko , Soo-suk Lee , Hun-joo Lee , Gal Ju , Joon-soo Han
发明人： Christopher Ko , Soo-suk Lee , Hun-joo Lee , Gal Ju , Joon-soo Han
IPC分类号： C12Q1/68 , G06F19/00 , G01N33/48 , G01N33/50
CPC分类号： G01N33/54373 , B01J2219/00527 , B01J2219/00547 , B01J2219/00565 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01L3/545 , B01L2300/022 , B01L2300/0819 , G01N2035/00782
摘要： A biochip with a radio frequency (RF) identification (ID) chip attached thereto, a hybridization system, and a hybridization management method are provided. Probes used for analyzing living body molecules are highly integrated on a substrate of the biochip, and biochip information including information obtained in the process of combining the living body molecules with the probes of the biochip is recorded in the RF ID tag of the biochip. Accordingly, it is possible to efficiently manage the biochip information using the RF ID tag and to prevent the biochip from being reused.
摘要翻译：提供了附有射频（RF）识别（ID）芯片的生物芯片，杂交系统和杂交管理方法。用于分析活体分子的探针高度集成在生物芯片的基板上，并且生物芯片信息包括在生物芯片的生物体分子与生物芯片的探针组合的过程中获得的信息。因此，可以使用RF ID标签有效地管理生物芯片信息，并且防止生物芯片被再次使用。

2. 发明申请

US20060154360A1 Hybridization system using the control of pump and valves in closed system 失效
标题翻译：混合系统使用封闭系统中的泵和阀的控制
公开(公告)号：US20060154360A1
公开(公告)日：2006-07-13
申请号：US11295843
申请日：2005-12-06
申请人： Soo-suk Lee , Sung-ouk Jung , Chang-eun Yoo , Hun-joo Lee , Christopher Ko , Nam Huh
发明人： Soo-suk Lee , Sung-ouk Jung , Chang-eun Yoo , Hun-joo Lee , Christopher Ko , Nam Huh
IPC分类号： C12M1/34
CPC分类号： B01L7/00 , B01F13/0059 , B01F13/0222 , B01L3/5027 , B01L2200/0689 , B01L2300/0636 , B01L2300/14 , B01L2300/1822 , B01L2400/0487 , G01N2035/00544
摘要： Provided is a hybridization system for hybridizing a biochip including: a chamber device including at least a hybridization chamber including a support for a biochip and a first cover having a sample inlet; an agitation device including: two air channels connected to ends of the hybridization chamber; two valves disposed in the air channels; an integrated air channel to which the two air channels are connected; and an air pump disposed in the integrated air channel; and a washing and drying device including: a flow channel connected to one of the two air channels through a branched valve; a flow pump disposed in the flow channel; and a buffer inlet disposed opposite the flow channel.
摘要翻译：提供了一种用于杂交生物芯片的杂交系统，包括：至少包括一个包括用于生物芯片的支撑物的杂交室的腔室装置和具有样品入口的第一盖子; 一种搅拌装置，包括：两个连接到杂交室端部的空气通道; 设置在空气通道中的两个阀; 两个空气通道连接的集成空气通道; 以及设置在所述集成空气通道中的空气泵; 以及洗涤干燥装置，包括：流路，其通过分支阀连接到所述两个空气通道中的一个; 设置在流路中的流量泵; 以及与流动通道相对设置的缓冲器入口。

3. 发明授权

US07732191B2 Hybridization system using the control of pump and valves in closed system 失效
标题翻译：混合系统使用封闭系统中的泵和阀的控制
公开(公告)号：US07732191B2
公开(公告)日：2010-06-08
申请号：US11295843
申请日：2005-12-06
申请人： Soo-suk Lee , Sung-ouk Jung , Chang-eun Yoo , Hun-joo Lee , Christopher Hansung Ko , Nam Huh
发明人： Soo-suk Lee , Sung-ouk Jung , Chang-eun Yoo , Hun-joo Lee , Christopher Hansung Ko , Nam Huh
IPC分类号： C12M1/34 , C12M1/36
CPC分类号： B01L7/00 , B01F13/0059 , B01F13/0222 , B01L3/5027 , B01L2200/0689 , B01L2300/0636 , B01L2300/14 , B01L2300/1822 , B01L2400/0487 , G01N2035/00544
摘要： Provided is a hybridization system for hybridizing a biochip including: a chamber device including at least a hybridization chamber including a support for a biochip and a first cover having a sample inlet; an agitation device including: two air channels connected to ends of the hybridization chamber; two valves disposed in the air channels; an integrated air channel to which the two air channels are connected; and an air pump disposed in the integrated air channel; and a washing and drying device including: a flow channel connected to one of the two air channels through a branched valve; a flow pump disposed in the flow channel; and a buffer inlet disposed opposite the flow channel.
摘要翻译：提供了一种用于杂交生物芯片的杂交系统，包括：至少包括一个包括用于生物芯片的支撑物的杂交室的腔室装置和具有样品入口的第一盖子; 一种搅拌装置，包括：两个连接到杂交室端部的空气通道; 设置在空气通道中的两个阀; 两个空气通道连接的集成空气通道; 以及设置在所述集成空气通道中的空气泵; 以及洗涤干燥装置，包括：流路，其通过分支阀连接到所述两个空气通道中的一个; 设置在流路中的流量泵; 以及与流动通道相对设置的缓冲器入口。

4. 发明授权

US08343325B2 Electrodialysis apparatus and electrodialysis method using the same 有权
标题翻译：电渗析装置及使用其的电渗析方法
公开(公告)号：US08343325B2
公开(公告)日：2013-01-01
申请号：US11737448
申请日：2007-04-19
申请人： Hun-joo Lee , Soo-suk Lee , Joon-ho Kim , Sung-ouk Jung , In-ho Lee
发明人： Hun-joo Lee , Soo-suk Lee , Joon-ho Kim , Sung-ouk Jung , In-ho Lee
IPC分类号： B01D61/44
CPC分类号： B01D61/422 , B01D2311/243 , B01D2313/02 , B01D2313/10 , B01D2313/26 , B01D2313/30 , B01D2313/50 , B01D2321/185
摘要： An electrodialysis apparatus includes a sample chamber including first and second dialysis membranes and filled with a sample between the first dialysis membrane and the second dialysis membrane, an anode chamber including an anode and filled with a first chamber solution between the anode and the first dialysis membrane, and a cathode chamber including a cathode and filled with a second chamber solution between the cathode and the second dialysis membrane. In particular, when a voltage is applied to the anode and the cathode, ionic materials of the sample move to the anode and cathode chambers.
摘要翻译：电渗透装置包括：样品室，包括第一和第二透析膜，并在第一透析膜和第二透析膜之间填充样品;阳极室，包括阳极，并在阳极和第一透析膜之间填充第一室溶液以及包括阴极并在阴极和第二透析膜之间填充有第二室溶液的阴极室。特别地，当向阳极和阴极施加电压时，样品的离子材料移动到阳极室和阴极室。

5. 发明授权

US08263671B2 Ion exchangeable mixture and method of producing the same 有权
标题翻译：可离子交换混合物及其制备方法
公开(公告)号：US08263671B2
公开(公告)日：2012-09-11
申请号：US13086741
申请日：2011-04-14
申请人： Hun-joo Lee , Ji-na Namgoong , Soo-suk Lee , Joon-ho Kim
发明人： Hun-joo Lee , Ji-na Namgoong , Soo-suk Lee , Joon-ho Kim
IPC分类号： B01J49/00 , C08J5/20 , C01B31/16
CPC分类号： C08J5/2218 , B01J39/20 , B01J41/14 , B01J47/016 , B01J47/12 , B01L3/5027 , C08J5/20
摘要： An ion exchangeable mixture containing a polymeric compound consisting of an ion exchange resin, an acrylamide mixture containing at least one bisacrylamide and at least one acrylamide, and a copolymer obtained by reacting the polymeric compound with the acrylamide mixture, and a method of producing the same are provided. The ion exchangeable membrane produced by using the ion exchangeable mixture has significantly smaller electric resistance than conventional ion exchangeable membranes, and has excellent selective permeability because the ion exchangeable membrane is electrically charged. The ion exchangeable membrane can be produced under very mild production conditions, and thus can be produced very easily. Furthermore, the ion exchangeable membrane can be also formed into film during a crosslinking reaction in a solvent of water, and thus is advantageous in that the ion exchangeable membrane can be freely produced into desired sizes, shapes and forms.
摘要翻译：含有由离子交换树脂，含有至少一种双丙烯酰胺和至少一种丙烯酰胺的丙烯酰胺混合物组成的聚合物的离子交换性混合物和通过使聚合物与丙烯酰胺混合物反应得到的共聚物及其制造方法被提供。通过使用离子交换性混合物制造的离子交换膜的电阻比常规的离子交换膜的电阻小得多，并且由于可离子交换膜带电而具有优异的选择性渗透性。离子交换膜可以在非常温和的生产条件下生产，因此可以非常容易地生产。此外，在水的溶剂中的交联反应期间，也可以将离子交换膜形成为膜，因此有利的是可离子交换膜可以自由地制成所需的尺寸，形状和形状。

6. 发明授权

US07544505B2 Hybridization chamber agitation device using pump and valves 失效
标题翻译：使用泵和阀的杂化室搅拌装置
公开(公告)号：US07544505B2
公开(公告)日：2009-06-09
申请号：US11295844
申请日：2005-12-06
申请人： Sung-ouk Jung , Nam Huh , Soo-suk Lee , Chang-eun Yoo , Hun-joo Lee
发明人： Sung-ouk Jung , Nam Huh , Soo-suk Lee , Chang-eun Yoo , Hun-joo Lee
IPC分类号： C12M1/34
CPC分类号： B01L3/502738 , B01F13/0059 , B01F13/0222 , B01L3/50273 , B01L7/52 , B01L2300/0636 , B01L2300/0822 , B01L2300/0877
摘要： Provided is an agitation device used to agitate a solution in a hybridization chamber, the agitation device including: the hybridization chamber; first and second air channels connected to ends of the hybridization chamber; a first valve disposed in the first air channel; a second valve disposed in the second air channel; an integrated air channel connecting the first and second air channels; and a pump disposed in the integrated air channel. The agitation device is suitable for effective diffusion of a sample when performing hybridization using a DNA chip. Therefore, a probe can be effectively hybridized with a target material.
摘要翻译：提供了用于搅拌杂交室中的溶液的搅拌装置，搅拌装置包括：杂交室; 第一和第二空气通道连接到杂交室的末端; 设置在第一空气通道中的第一阀; 设置在第二空气通道中的第二阀; 连接第一和第二空气通道的集成空气通道; 以及设置在集成空气通道中的泵。搅拌装置适用于使用DNA芯片进行杂交时样品的有效扩散。因此，探针可以有效地与靶材料杂交。

7. 发明申请

US20060099711A1 Cell lysis method by immobilized metal-ligand complex 失效
标题翻译：固定化金属配体复合物的细胞裂解法
公开(公告)号：US20060099711A1
公开(公告)日：2006-05-11
申请号：US11267005
申请日：2005-11-04
申请人： Chang-eun Yoo , Joon-ho Kim , Kyu-youn Hwang , Hun-joo Lee , Hee-kyun Lim , Soo-min Ma , Nam Huh , Soo-suk Lee
发明人： Chang-eun Yoo , Joon-ho Kim , Kyu-youn Hwang , Hun-joo Lee , Hee-kyun Lim , Soo-min Ma , Nam Huh , Soo-suk Lee
IPC分类号： G01N1/00
CPC分类号： C12Q1/6806 , Y10T436/25 , C12Q2523/308
摘要： Provided is a lysis method for cells or viruses, including: immobilizing a metal-ligand complex on a solid support; and mixing the complex immobilized on the support with a cell or virus solution. According to the lysis method, by immobilizing a chemical on a solid support to perform cell lysis, the dilution problem according to the addition of a cell lysis solution can be resolved and a separate process of removing the chemical is not required so as to reduce the steps upon LOC implementation. In addition, since a variety of solid supports, such as chips, beads, nanoparticles etc. can be used, cell lysis apparatuses of various forms can be fabricated.
摘要翻译：提供了一种细胞或病毒的裂解方法，包括：将固定支持物上的金属 - 配体复合物固定; 并将固定在载体上的复合物与细胞或病毒溶液混合。根据裂解方法，通过将化学物质固定在固体支持体上以进行细胞裂解，可以解决根据细胞溶解溶液的添加的稀释问题，并且不需要单独的除去化学品的方法，以减少 LOC实施步骤。此外，由于可以使用各种固体支持体，例如芯片，珠粒，纳米粒子等，因此可以制造各种形式的细胞裂解装置。

8. 发明授权

US08519014B2 Ion exchangeable mixture and method of producing the same 有权
标题翻译：可离子交换混合物及其制备方法
公开(公告)号：US08519014B2
公开(公告)日：2013-08-27
申请号：US13605503
申请日：2012-09-06
申请人： Hun-joo Lee , Ji-na Namgoong , Soo-suk Lee , Joon-ho Kim
发明人： Hun-joo Lee , Ji-na Namgoong , Soo-suk Lee , Joon-ho Kim
IPC分类号： B01J49/00 , C08J5/20 , C01B31/16
CPC分类号： C08J5/2218 , B01J39/20 , B01J41/14 , B01J47/016 , B01J47/12 , B01L3/5027 , C08J5/20
摘要： An ion exchangeable mixture containing a polymeric compound consisting of an ion exchange resin, an acrylamide mixture containing at least one bisacrylamide and at least one acrylamide, and a copolymer obtained by reacting the polymeric compound with the acrylamide mixture, and a method of producing the same are provided. The ion exchangeable membrane produced by using the ion exchangeable mixture has significantly smaller electric resistance than conventional ion exchangeable membranes, and has excellent selective permeability because the ion exchangeable membrane is electrically charged. The ion exchangeable membrane can be produced under very mild production conditions, and thus can be produced very easily. Furthermore, the ion exchangeable membrane can be also formed into film during a crosslinking reaction in a solvent of water, and thus is advantageous in that the ion exchangeable membrane can be freely produced into desired sizes, shapes and forms.
摘要翻译：含有由离子交换树脂，含有至少一种双丙烯酰胺和至少一种丙烯酰胺的丙烯酰胺混合物组成的聚合物的离子交换性混合物和通过使聚合物与丙烯酰胺混合物反应得到的共聚物及其制造方法被提供。通过使用离子交换性混合物制造的离子交换膜的电阻比常规的离子交换膜的电阻小得多，并且由于可离子交换膜带电而具有优异的选择性渗透性。离子交换膜可以在非常温和的生产条件下生产，因此可以非常容易地生产。此外，在水的溶剂中的交联反应期间，也可以将离子交换膜形成为膜，因此有利的是可离子交换膜可以自由地制成所需的尺寸，形状和形状。

9. 发明授权

US07947196B2 Ion exchangeable mixture and method of producing the same 有权
标题翻译：可离子交换混合物及其制备方法
公开(公告)号：US07947196B2
公开(公告)日：2011-05-24
申请号：US11453116
申请日：2006-06-14
申请人： Hun-joo Lee , Ji-na Namgoong , Soo-suk Lee , Joon-ho Kim
发明人： Hun-joo Lee , Ji-na Namgoong , Soo-suk Lee , Joon-ho Kim
IPC分类号： C01B31/16
CPC分类号： C08J5/2218 , B01J39/20 , B01J41/14 , B01J47/016 , B01J47/12 , B01L3/5027 , C08J5/20
摘要： An ion exchangeable mixture containing a polymeric compound consisting of an ion exchange resin, an acrylamide mixture containing at least one bisacrylamide and at least one acrylamide, and a copolymer obtained by reacting the polymeric compound with the acrylamide mixture, and a method of producing the same are provided. The ion exchangeable membrane produced by using the ion exchangeable mixture has significantly smaller electric resistance than conventional ion exchangeable membranes, and has excellent selective permeability because the ion exchangeable membrane is electrically charged. The ion exchangeable membrane can be produced under very mild production conditions, and thus can be produced very easily. Furthermore, the ion exchangeable membrane can be also formed into film during a crosslinking reaction in a solvent of water, and thus is advantageous in that the ion exchangeable membrane can be freely produced into desired sizes, shapes and forms.
摘要翻译：含有由离子交换树脂，含有至少一种双丙烯酰胺和至少一种丙烯酰胺的丙烯酰胺混合物组成的聚合物的离子交换性混合物和通过使聚合物与丙烯酰胺混合物反应得到的共聚物及其制造方法被提供。通过使用离子交换性混合物制造的离子交换膜的电阻比常规的离子交换膜的电阻小得多，并且由于可离子交换膜带电而具有优异的选择性渗透性。离子交换膜可以在非常温和的生产条件下生产，因此可以非常容易地生产。此外，在水的溶剂中的交联反应期间，也可以将离子交换膜形成为膜，因此有利的是可离子交换膜可以自由地制成所需的尺寸，形状和形状。

10. 发明授权

US07819138B2 Microfluidic device using centrifugal force and pump to control fluid movement, microfluidic system comprising the same and method of manufacturing the microfluidic device 有权
标题翻译：使用离心力和泵来控制流体运动的微流体装置，包括其的微流体系统和制造微流体装置的方法
公开(公告)号：US07819138B2
公开(公告)日：2010-10-26
申请号：US11869835
申请日：2007-10-10
申请人： Hun-joo Lee , Nam Huh , Soo-suk Lee , Sung-ouk Jung , Soo-hyung Choi
发明人： Hun-joo Lee , Nam Huh , Soo-suk Lee , Sung-ouk Jung , Soo-hyung Choi
IPC分类号： F15C1/04
CPC分类号： G05D7/0694 , Y10T29/494 , Y10T137/0753 , Y10T137/2191 , Y10T137/86187
摘要： The microfluidic device includes a rotatable platform, a plurality of connection ports disposed at a portion of the platform proximate to a shaft connection hole, the plurality of connection ports capable of being connected to an external connector for selectively injecting and discharging fluid and being closed by the connector, a trap chamber disposed at a portion of the platform further away from the shaft connection hole than the plurality of connection ports, the trap chamber including an inlet connected with at least one connection port of the plurality of connection ports, an outlet connected with another connection port of the plurality of connection ports and structures which enlarge a contact area with the fluid and a temporary storage including an inlet connected with the outlet of the trap chamber and an outlet connected with another connection port of the plurality of connection ports.
摘要翻译：所述微流体装置包括可旋转平台，多个连接端口，设置在所述平台的靠近轴连接孔的部分处，所述多个连接端口能够连接到外部连接器，用于选择性地注入和排出流体并且由所述连接器，设置在所述平台的远离所述轴连接孔的所述平台部分处的所述收集室，所述收集室包括与所述多个连接端口中的至少一个连接端口连接的入口，所述入口连接到所述入口多个连接端口中的另一个连接端口和扩大与流体的接触面积的结构以及包括与捕集室的出口连接的入口的临时存储器和与多个连接端口中的另一连接端口连接的出口。

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