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1. 发明授权

US08668665B2 Systems and methods for power and flow rate control 有权
公开(公告)号：US08668665B2
公开(公告)日：2014-03-11
申请号：US13243721
申请日：2011-09-23
申请人： James Gerg , Carina R Reisin
发明人： James Gerg , Carina R Reisin
IPC分类号： A61M1/00 , A61M5/178 , A61M31/00
CPC分类号： A61M1/0031 , A61B2017/00084 , A61F9/00736 , A61M1/0035 , A61M1/0058
摘要： The invention is generally directed to systems and methods for fluid control, and more particularly to systems and methods for power and flow rate control for aspiration. In accordance with one embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.

2. 发明申请

US20120059465A1 CAPSULAR MEMBRANE IMPLANTS TO INCREASE ACCOMMODATIVE AMPLITUDE 有权
标题翻译：囊体膜植入物增加舒张功能
公开(公告)号：US20120059465A1
公开(公告)日：2012-03-08
申请号：US13043178
申请日：2011-03-08
申请人： Daniel G. Brady , Zsolt Bor , Edward Geraghty , Brooke C. Basinger , Carina R. Reisin , Douglas S. Cali
发明人： Daniel G. Brady , Zsolt Bor , Edward Geraghty , Brooke C. Basinger , Carina R. Reisin , Douglas S. Cali
IPC分类号： A61F2/16
CPC分类号： A61F2/14 , A61F2/1624 , A61F9/00736 , A61F9/008 , A61F9/00838 , A61F2002/1681 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895 , F04C2270/0421
摘要： A support is coupled to the lens capsule to increase accommodation. The support may be adjustable, such that patient refraction and accommodation can be adjusted following surgery. The support may comprise rigidity sufficient to decrease radial movement of the intermediate portion of the lens capsule. The support can be placed on the intermediate portion to decrease radial movement of the intermediate portion of the lens capsule and increase radial stretching of an outer portion of the lens capsule extending between the zonules and the intermediate portion coupled to the support, such that the amount of accommodation of the eye is increased. The support may comprise a biocompatible material capable of stable coupling to the lens capsule following implantation, such that the far vision refraction and accommodation of the eye can be stable following surgery.
摘要翻译：支撑件联接到镜片胶囊以增加调节。支撑件可以是可调节的，使得在手术后可以调整患者的折射和容纳。支撑件可以包括足以减小透镜胶囊的中间部分的径向移动的刚度。可以将支撑件放置在中间部分上以减小透镜胶囊的中间部分的径向移动，并且增加透镜胶囊的在部分与连接到支撑件的中间部分之间延伸的外部部分的径向拉伸，使得量眼睛的适应性增加。支撑体可以包括能够在植入之后稳定地耦合到晶状体囊的生物相容性材料，使得眼睛的远视力折射和适应在手术后可以是稳定的。

3. 发明申请

US20110054601A1 FIXATION OF OPTHALMIC IMPLANTS 有权
标题翻译： OPALALMIC植入物的固定
公开(公告)号：US20110054601A1
公开(公告)日：2011-03-03
申请号：US12870570
申请日：2010-08-27
申请人： Kenneth E. Kadziauskas , Carina R. Reisin , Timothy R. Bumbalough
发明人： Kenneth E. Kadziauskas , Carina R. Reisin , Timothy R. Bumbalough
IPC分类号： A61F2/16 , A61M5/00
CPC分类号： A61F2/1624 , A61F2/1635 , A61F9/00781 , A61F2002/009 , A61F2002/1681 , A61F2002/1682 , A61F2220/0008 , A61F2220/0016 , A61F2250/0003
摘要： An accommodating intraocular lens (aIOL) is disclosed, with an optic that changes shape in response to an ocular force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. A surface adherent improves the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. One way to enhance force transfer is to provide a surface layer of an adhesive to the haptic and/or optic, for instance a reversible bioadhesive material. Or, portions of the exterior surface of the IOL may have microfibers thereon that mimic the adhesive properties of Gecko feet. Another aspect is application of a reversible bioadhesive material to the interior of the empty capsular bag prior to introduction of an injectable polymer IOL.
摘要翻译：公开了一种适应性眼内透镜（aIOL），其具有响应于由眼睛的小区施加的眼部力而改变形状的光学元件。触觉件支持其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。表面贴附改善了触觉件的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到光学元件。增强力传递的一种方式是向触觉和/或光学元件提供粘合剂的表面层，例如可逆的生物粘附材料。或者，IOL的外表面的部分可能在其上具有模拟Gecko脚的粘合性质的微纤维。另一方面是在引入可注射聚合物IOL之前将可逆生物粘附材料施用于空的囊袋的内部。

4. 发明授权

US09278026B2 Capsular membrane treatments to increase accommodative amplitude 有权
标题翻译：荚膜治疗增加调节幅度
公开(公告)号：US09278026B2
公开(公告)日：2016-03-08
申请号：US13043149
申请日：2011-03-08
申请人： Zsolt Bor , Daniel G. Brady , Edward Geraghty , Carina R. Reisin , Douglas S. Cali
发明人： Zsolt Bor , Daniel G. Brady , Edward Geraghty , Carina R. Reisin , Douglas S. Cali
IPC分类号： A61F2/14 , A61B18/18 , A61F9/007 , A61F9/008 , A61F2/16
CPC分类号： A61F9/013 , A61F2/16 , A61F9/00 , A61F9/0008 , A61F9/0017 , A61F9/007 , A61F9/00736 , A61F9/0079 , A61F9/008 , A61F9/00838 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895
摘要： Methods and apparatus treat the lens capsule so as to increase accommodation of the eye. The treatment of the lens capsule may comprise treating a portion of the lens capsule so as to stiffen the treated portion and improve accommodation of the eye. The intermediate portion of the lens capsule may located between an optically used central portion of the lens capsule and a peripheral portion of the lens capsule connected to zonules of the eye. The stiffened intermediate portion of the lens capsule can improve coupling of the peripheral portion of the lens capsule to the central portion of the lens capsule, such that an amount of accommodation of the optically used central portion of the lens is increased. As the force of the lens capsule to a lens disposed within the lens capsule is increased, the lens may comprise the natural lens of the eye or an artificial lens such as an accommodative IOL. The treatment of the eye to stiffen the intermediate portion may comprise application of one or more of an energy or a substance to the intermediate portion.
摘要翻译：方法和装置处理晶状体囊以增加眼睛的适应性。透镜胶囊的治疗可以包括处理透镜胶囊的一部分，以便加强经处理的部分并改善眼睛的适应性。透镜胶囊的中间部分可以位于透镜胶囊的光学使用的中心部分和与眼睛的小区连接的透镜胶囊的周边部分之间。透镜胶囊的加强的中间部分可以改善透镜胶囊的周边部分与透镜胶囊的中心部分的联接，使得透镜的光学中心部分的调节量增加。当透镜胶囊对设置在透镜胶囊内的透镜的力增加时，透镜可以包括眼睛的天然晶状体或诸如调节性IOL的人造镜片。治疗眼睛以加强中间部分可以包括向中间部分施加一种或多种能量或物质。

5. 发明授权

US08430841B2 Application of vacuum as a method and mechanism for controlling eye chamber stability 有权
公开(公告)号：US08430841B2
公开(公告)日：2013-04-30
申请号：US12695812
申请日：2010-01-28
申请人： Michael J Claus , Wayne S Wong , Carina R Reisin , Stephen H Jang
发明人： Michael J Claus , Wayne S Wong , Carina R Reisin , Stephen H Jang
IPC分类号： A61M1/00
CPC分类号： A61F9/00745 , A61M3/0283
摘要： A phacoemulsification system for operating a surgical handpiece having a handpiece; an irrigation fluid source for supplying irrigation fluid to the eye; an aspiration source coupled to the handpiece in order to aspirate the irrigation fluid from the eye through the handpiece; and a controller for controlling a vacuum in the handpiece, the controller comprising: a sensor for sensing the vacuum in the handpiece; an occlusion parameter, the occlusion parameter being a vacuum level corresponding to an occlusion of the handpiece or a flow rate corresponding to an occlusion of the handpiece; a maximum allowable vacuum level in the handpiece, the maximum allowable vacuum level having at least a first predetermined level; and a trigger value that is set based in part on the occlusion parameter.

6. 发明申请

US20110029074A1 FIXATION OF OPHTHALMIC IMPLANTS 审中-公开
标题翻译：透明植入物的固定
公开(公告)号：US20110029074A1
公开(公告)日：2011-02-03
申请号：US12685426
申请日：2010-01-11
申请人： Carina R. Reisin , Kenneth E. Kadziauskas , Brooke C. Basinger , Timothy R. Bumbalough
发明人： Carina R. Reisin , Kenneth E. Kadziauskas , Brooke C. Basinger , Timothy R. Bumbalough
IPC分类号： A61F2/16 , A61M5/00 , A61F9/00
CPC分类号： A61F2/1613 , A61F2/1624 , A61F9/007 , A61F2220/0008 , A61F2220/005
摘要： An ophthalmic device for implantation into a capsular bag of an eye includes an adhesive or adherent that adheres to an eye at certain temperatures or other physical conditions, but has little or no adherence at other temperatures. The ophthalmic device may be an accommodating intraocular lens including an adjustable optic body and a support structure. The support structure includes an outer structure, an intermediate structure, and an adhesive or adherent material disposed over at least a portion of the support structure. The intermediate structure is located between, and connected to, the outer structure and the optic body. The outer structure has an outer face configured for engaging a capsular bag of an eye. The outer face includes an equatorial region, with anterior and posterior regions disposed on opposite sides of the equatorial region. Under a predetermined condition, the posterior region has an adhesion that is greater than an adhesion of the anterior region.
摘要翻译：用于植入眼睛囊袋的眼科装置包括在某些温度或其他物理条件下粘附于眼睛的粘合剂或附着物，但在其它温度下几乎不粘附或不粘附。眼科装置可以是包括可调节光学主体和支撑结构的容纳眼内透镜。支撑结构包括外部结构，中间结构以及设置在支撑结构的至少一部分上的粘合或粘附材料。中间结构位于外部结构和光学主体之间并连接到外部结构和光学主体。外部结构具有被配置用于接合眼睛囊袋的外表面。外表面包括赤道区域，前后区域设置在赤道区域的相对两侧。在预定条件下，后部区域具有大于前部区域的粘附的粘附。

7. 发明授权

US09072599B2 Fixation of ophthalmic implants 有权
标题翻译：眼科植入物的固定
公开(公告)号：US09072599B2
公开(公告)日：2015-07-07
申请号：US12870570
申请日：2010-08-27
申请人： Kenneth E. Kadziauskas , Carina R. Reisin , Timothy R. Bumbalough
发明人： Kenneth E. Kadziauskas , Carina R. Reisin , Timothy R. Bumbalough
IPC分类号： A61F2/16 , A61F9/007 , A61F2/00
CPC分类号： A61F2/1624 , A61F2/1635 , A61F9/00781 , A61F2002/009 , A61F2002/1681 , A61F2002/1682 , A61F2220/0008 , A61F2220/0016 , A61F2250/0003
摘要： An accommodating intraocular lens (aIOL) is disclosed, with an optic that changes shape in response to an ocular force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. A surface adherent improves the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. One way to enhance force transfer is to provide a surface layer of an adhesive to the haptic and/or optic, for instance a reversible bioadhesive material. Or, portions of the exterior surface of the IOL may have microfibers thereon that mimic the adhesive properties of Gecko feet. Another aspect is application of a reversible bioadhesive material to the interior of the empty capsular bag prior to introduction of an injectable polymer IOL.
摘要翻译：公开了一种适应性眼内透镜（aIOL），其具有响应于由眼睛的小区施加的眼部力而改变形状的光学元件。触觉件支持其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。表面贴附改善了触觉件的调节性能，使得压缩/拉伸力可以更有效地从触觉传递到光学元件。增强力传递的一种方式是向触觉和/或光学元件提供粘合剂的表面层，例如可逆的生物粘附材料。或者，IOL的外表面的部分可能在其上具有模拟Gecko脚的粘合性质的微纤维。另一方面是在引入可注射聚合物IOL之前将可逆生物粘附材料施用于空的囊袋的内部。

8. 发明申请

US20120059363A1 CAPSULAR MEMBRANE TREATMENTS TO INCREASE ACCOMMODATIVE AMPLITUDE 有权
标题翻译： CAPSULAR膜治疗增加舒张功能
公开(公告)号：US20120059363A1
公开(公告)日：2012-03-08
申请号：US13043149
申请日：2011-03-08
申请人： Zsolt Bor , Daniel G. Brady , Edward Geraghty , Carina R. Reisin , Douglas S. Cali
发明人： Zsolt Bor , Daniel G. Brady , Edward Geraghty , Carina R. Reisin , Douglas S. Cali
IPC分类号： A61B18/20
CPC分类号： A61F9/013 , A61F2/16 , A61F9/00 , A61F9/0008 , A61F9/0017 , A61F9/007 , A61F9/00736 , A61F9/0079 , A61F9/008 , A61F9/00838 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895
摘要： Methods and apparatus treat the lens capsule so as to increase accommodation of the eye. The treatment of the lens capsule may comprise treating a portion of the lens capsule so as to stiffen the treated portion and improve accommodation of the eye. The intermediate portion of the lens capsule may located between an optically used central portion of the lens capsule and a peripheral portion of the lens capsule connected to zonules of the eye. The stiffened intermediate portion of the lens capsule can improve coupling of the peripheral portion of the lens capsule to the central portion of the lens capsule, such that an amount of accommodation of the optically used central portion of the lens is increased. As the force of the lens capsule to a lens disposed within the lens capsule is increased, the lens may comprise the natural lens of the eye or an artificial lens such as an accommodative IOL. The treatment of the eye to stiffen the intermediate portion may comprise application of one or more of an energy or a substance to the intermediate portion.
摘要翻译：方法和装置处理晶状体囊以增加眼睛的适应性。透镜胶囊的治疗可以包括处理透镜胶囊的一部分，以便加强经处理的部分并改善眼睛的适应性。透镜胶囊的中间部分可以位于透镜胶囊的光学使用的中心部分和与眼睛的小区连接的透镜胶囊的周边部分之间。透镜胶囊的加强中间部分可以改善透镜胶囊的周边部分与透镜胶囊的中心部分的联接，使得透镜的光学中心部分的调节量增加。当透镜胶囊对设置在透镜胶囊内的透镜的力增加时，透镜可以包括眼睛的天然晶状体或诸如调节性IOL的人造镜片。治疗眼睛以加强中间部分可以包括向中间部分施加一种或多种能量或物质。

9. 发明授权

US06710758B2 Spatial light modulators with improved inter-pixel performance 失效
标题翻译：具有改善的像素间性能的空间光调制器
公开(公告)号：US06710758B2
公开(公告)日：2004-03-23
申请号：US10328128
申请日：2002-12-19
申请人： Lisa A. Caracci , John P. Kondis , Robert G. Lindquist , Rui-Qing Ma , Carina R. Reisin , Bradley A. Scott
发明人： Lisa A. Caracci , John P. Kondis , Robert G. Lindquist , Rui-Qing Ma , Carina R. Reisin , Bradley A. Scott
IPC分类号： G09G334
CPC分类号： G02F1/133345 , G02F1/133553 , G02F2202/42
摘要： A reflective spatial light modulator (SLM) includes a first substrate, a second substrate and an electro-optic material positioned between the first and second substrates. The first substrate includes a reflective ground layer that acts as a continuous first electrode and the second substrate includes a pixel layer having a plurality of pixel elements formed in a pattern. The pixel elements are formed of a transparent conductive material and are separated by inter-pixel regions formed of a non-conductive material. A transmissivity of the electro-optic material in a vicinity of each of the plurality of pixel elements is controlled by a potential difference applied between the first electrode and a respective one of the pixel elements.
摘要翻译：反射空间光调制器（SLM）包括第一基板，第二基板和位于第一和第二基板之间的电光材料。第一衬底包括用作连续的第一电极的反射接地层，并且第二衬底包括具有以图案形成的多个像素元件的像素层。像素元件由透明导电材料形成，并且由由非导电材料形成的像素间区域分开。通过施加在第一电极和相应的像素元件之间的电位差来控制电光材料在多个像素元件中的每一个附近的透射率。

10. 发明授权

US08715220B2 Systems and methods for power and flow rate control 有权
标题翻译：电力和流量控制的系统和方法
公开(公告)号：US08715220B2
公开(公告)日：2014-05-06
申请号：US13243765
申请日：2011-09-23
申请人： James Gerg , Carina R Reisin
发明人： James Gerg , Carina R Reisin
IPC分类号： A61M1/00 , A61M5/178 , A61M31/00
CPC分类号： A61M1/0031 , A61B2017/00084 , A61F9/00736 , A61M1/0035 , A61M1/0058
摘要： Systems and methods for fluid control during aspiration. In an embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.
摘要翻译：抽吸过程中流体控制的系统和方法。在一个实施例中，抽吸系统包括具有远端和近端的抽吸管线和限定在远端中的抽吸口; 流体输送装置，其可操作地耦合到所述吸入管线的近端; 以及限流器，其可操作地联接到所述流体输送装置和所述抽吸端口之间的所述抽吸管线。为了测量线内的闭塞，利用第一和第二压力传感器，第一传感器可操作地耦合到端口和节流器之间的抽吸管线，并且第二传感器可操作地联接到限制器和流体输送装置之间的抽吸管线。两个传感器之间的压力差可以提供闭塞的开始，存在和/或消除的指示。

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