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    • 2. 发明申请
    • BIOLOGICAL INDICATOR FOR USE WITH VAPOROUS MICROBIAL DEACTIVATING AGENTS AND METHOD FOR MAKING SAME
    • 用于蒸气微生物消毒剂的生物指示剂及其制备方法
    • US20080206801A1
    • 2008-08-28
    • US11679208
    • 2007-02-27
    • Anthony W. DallmierChristopher W. FisherTimothy J. Millett
    • Anthony W. DallmierChristopher W. FisherTimothy J. Millett
    • C12Q1/02
    • C12Q1/02C12M37/06
    • A biological indicator and method of making same. The biological indicator includes a carrier having a recess formed therein in order to restrict movement of an inoculum deposited onto the carrier. The inoculum includes microorganisms (e.g., bacterial spores) suspended in a suspension medium. The microorganisms are prepared by removing extraneous material and subjecting the microorganisms to sonication to break up agglomerations. The suspension medium includes a wetting agent to reduce surface tension, thereby facilitating flow of the suspension medium to prevent stacking of microorganisms on the surface of the carrier, and to allow the inoculum to more evenly “plate out” on carrier surfaces. The carrier, with inoculum deposited thereon, is enclosed in an envelope made of a material permeable to a vaporous deactivating agent (e.g., vaporized hydrogen peroxide, ozone, chlorine dioxide, ethylene oxide, etc.), thereby facilitating exposure to the vaporous deactivating agent.
    • 生物指标及其制作方法。 生物指示剂包括其中形成有凹部的载体,以限制沉积在载体上的接种物的移动。 接种物包括悬浮在悬浮介质中的微生物(例如细菌孢子)。 微生物通过除去外来材料并使微生物进行超声处理以分解附聚物来制备。 悬浮介质包括润湿剂以降低表面张力,从而促进悬浮介质的流动以防止微生物在载体表面上堆积,并允许接种物在载体表面上更均匀地“平板化”。 将沉积有接种物的载体封闭在由可蒸发的钝化剂(例如蒸发的过氧化氢,臭氧,二氧化氯,环氧乙烷等)可渗透的材料制成的封套中,从而便于暴露于蒸气去活化剂 。
    • 4. 发明申请
    • METHOD FOR MAKING A BIOLOGICAL INDICATOR FOR USE WITH VAPOROUS MICROBIAL DEACTIVATING AGENTS
    • 制备生物指示剂的方法,用于与蒸气微生物消毒剂
    • US20090305334A1
    • 2009-12-10
    • US12539947
    • 2009-08-12
    • Anthony W. DallmierChristopher W. FisherTimothy J. Millett
    • Anthony W. DallmierChristopher W. FisherTimothy J. Millett
    • C12Q1/02C12N13/00
    • C12Q1/02C12M37/06
    • A biological indicator and method of making same. The biological indicator includes a carrier having a recess formed therein in order to restrict movement of an inoculum deposited onto the carrier. The inoculum includes microorganisms (e.g., bacterial spores) suspended in a suspension medium. The microorganisms are prepared by removing extraneous material and subjecting the microorganisms to sonication to break up agglomerations. The suspension medium includes a wetting agent to reduce surface tension, thereby facilitating flow of the suspension medium to prevent stacking of microorganisms on the surface of the carrier, and to allow the inoculum to more evenly “plate out” on carrier surfaces. The carrier, with inoculum deposited thereon, is enclosed in an envelope made of a material permeable to a vaporous deactivating agent (e.g., vaporized hydrogen peroxide, ozone, chlorine dioxide, ethylene oxide, etc.), thereby facilitating exposure to the vaporous deactivating agent.
    • 生物指标及其制作方法。 生物指示剂包括其中形成有凹部的载体,以限制沉积在载体上的接种物的移动。 接种物包括悬浮在悬浮介质中的微生物(例如细菌孢子)。 微生物通过除去外来材料并使微生物进行超声处理以分解附聚物来制备。 悬浮介质包括润湿剂以降低表面张力,从而促进悬浮介质的流动以防止微生物在载体表面上堆积,并允许接种物在载体表面上更均匀地“平板化”。 将沉积有接种物的载体封闭在由可蒸发的钝化剂(例如蒸发的过氧化氢,臭氧,二氧化氯,环氧乙烷等)可渗透的材料制成的封套中,从而便于暴露于蒸气去活化剂 。