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    • 2. 发明申请
    • SYSTEM FOR DISTRIBUTED BLOOD FLOW MEASUREMENT
    • 分布式血液流量测量系统
    • WO2012164481A1
    • 2012-12-06
    • PCT/IB2012/052665
    • 2012-05-29
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.'T HOOFT, Gert, WimDESJARDINS, Adrien, EmmanuelBARLEY, Maya, EllaCHAN, Raymond
    • 'T HOOFT, Gert, WimDESJARDINS, Adrien, EmmanuelBARLEY, Maya, EllaCHAN, Raymond
    • A61B5/026A61B5/028G01F1/688
    • A61B5/0261A61B5/028A61B5/6852A61B2562/0233G01F1/6884
    • A medical system for minimally-invasive measurement of blood flow in an artery(AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the IVD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.
    • 用于动脉(AT)血流量微创测量的医疗系统。 具有光纤(FB)的介入装置(IVD),其包括多个温度敏感的光学传感器段,例如, 沿着其纵向延伸部空间分布的光纤布拉格光栅被配置成插入到动脉(AT)中。 在IVD中布置了温度变换器(TC),以引入动脉中的血块的局部温度变化(ΔT),以允许随着光纤(FB)随时间的热跟踪。 具有激光光源(LS)的测量单元(MU)向光纤(FB)传送光并接收从光纤(FB)反射的光并产生相应的时变输出信号。 第一算法(A1)将该时变输出信号转换成对应于沿着光纤(FB)的相应位置处的温度的一组温度。 第二算法(A2)根据所述一组温度的时间特性计算沿着光纤(FB)的各个位置处的血流量(BF)的测量。 这种系统可用于快速扫描动脉以诊断狭窄区域,而不需要回吸或注射有毒液体。 可以实时获得血流测量的良好的空间分辨率。
    • 10. 发明申请
    • GUIDED DELIVERY OF PROSTHETIC VALVE
    • 导向阀的引导
    • WO2012147028A1
    • 2012-11-01
    • PCT/IB2012/052040
    • 2012-04-23
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.HARKS, Godefridus Antonius'T HOOFT, Gert WimCHAN, Raymond
    • HARKS, Godefridus Antonius'T HOOFT, Gert WimCHAN, Raymond
    • A61B19/00
    • A61F2/2427A61B34/20A61B2034/2061
    • An image-guided prosthetic valve deployment system employs a prosthetic valve (80), a catheter (70) and a delivery tracking system (90). The catheter (70) has an elongated body with a proximal tip (71a) and a distal tip (71b), and the elongated body includes a delivery section (72) adjacent the distal tip (71b) for deploying the prosthetic valve (80) relative to a heart valve (21) within an anatomical region (20). The delivery section (72) includes a delivery segment (73) for sensing a shape and an orientation of the delivery section (72) within the anatomical region (20) relative to a reference point (74). The delivery tracking system (90) tracks a position and an orientation of the prosthetic valve (80) relative to the heart valve (21) as a function of a sensed shape and a sensed orientation of the delivery section (72) within the anatomical region (20) relative to the reference point (74) by the delivery segment (73).
    • 图像引导假体瓣膜部署系统采用人造瓣膜(80),导管(70)和输送跟踪系统(90)。 所述导管(70)具有带有近端(71a)和远侧末端(71b)的细长主体,细长主体包括邻近远侧末端(71b)的用于展开人工瓣膜(80)的输送部分(72) 相对于解剖区域(20)内的心脏瓣膜(21)。 输送部分(72)包括用于相对于参考点(74)感测解剖区域(20)内的输送部分(72)的形状和取向的递送部分(73)。 递送跟踪系统(90)根据感测到的形状和传感部分(72)在解剖区域内的取向的函数来跟踪人造瓣膜(80)相对于心脏瓣膜(21)的位置和取向 (70)相对于参考点(74)的距离(20)。