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1. 发明申请

WO2012164481A1 SYSTEM FOR DISTRIBUTED BLOOD FLOW MEASUREMENT 审中-公开
标题翻译：分布式血液流量测量系统
公开(公告)号：WO2012164481A1
公开(公告)日：2012-12-06
申请号：PCT/IB2012/052665
申请日：2012-05-29
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , 'T HOOFT, Gert, Wim , DESJARDINS, Adrien, Emmanuel , BARLEY, Maya, Ella , CHAN, Raymond
发明人： 'T HOOFT, Gert, Wim , DESJARDINS, Adrien, Emmanuel , BARLEY, Maya, Ella , CHAN, Raymond
IPC分类号： A61B5/026 , A61B5/028 , G01F1/688
CPC分类号： A61B5/0261 , A61B5/028 , A61B5/6852 , A61B2562/0233 , G01F1/6884
摘要： A medical system for minimally-invasive measurement of blood flow in an artery(AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the IVD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.
摘要翻译：用于动脉（AT）血流量微创测量的医疗系统。具有光纤（FB）的介入装置（IVD），其包括多个温度敏感的光学传感器段，例如，沿着其纵向延伸部空间分布的光纤布拉格光栅被配置成插入到动脉（AT）中。在IVD中布置了温度变换器（TC），以引入动脉中的血块的局部温度变化（ΔT），以允许随着光纤（FB）随时间的热跟踪。具有激光光源（LS）的测量单元（MU）向光纤（FB）传送光并接收从光纤（FB）反射的光并产生相应的时变输出信号。第一算法（A1）将该时变输出信号转换成对应于沿着光纤（FB）的相应位置处的温度的一组温度。第二算法（A2）根据所述一组温度的时间特性计算沿着光纤（FB）的各个位置处的血流量（BF）的测量。这种系统可用于快速扫描动脉以诊断狭窄区域，而不需要回吸或注射有毒液体。可以实时获得血流测量的良好的空间分辨率。

2. 发明申请

WO2012056386A1 ADAPTIVE IMAGING AND FRAME RATE OPTIMIZING BASED ON REAL-TIME SHAPE SENSING OF MEDICAL INSTRUMENTS 审中-公开
标题翻译：基于医疗仪器实时形状检测的自适应成像和帧速率优化
公开(公告)号：WO2012056386A1
公开(公告)日：2012-05-03
申请号：PCT/IB2011/054728
申请日：2011-10-24
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , CHAN, Raymond , WANG, Jinnan , DESJARDINS, Adrien, Emmanuel , GUTIERREZ, Luis, Felipe , BARLEY, Maya, Ella , 't HOOFT, Gert, Wim
发明人： CHAN, Raymond , WANG, Jinnan , DESJARDINS, Adrien, Emmanuel , GUTIERREZ, Luis, Felipe , BARLEY, Maya, Ella , 't HOOFT, Gert, Wim
IPC分类号： A61B19/00
CPC分类号： A61B6/488 , A61B5/055 , A61B5/066 , A61B6/03 , A61B6/12 , A61B6/486 , A61B6/487 , A61B6/504 , A61B6/5229 , A61B6/54 , A61B6/542 , A61B34/20 , A61B2017/00075 , A61B2034/2051 , A61B2034/2061
摘要： A system and method for adaptive imaging include a shape sensing system (115, 117) coupled to an interventional device (102) to measure spatial characteristics of the interventional device in a subject. An image module (130) is configured to receive the spatial characteristics and generate one or more control signals in accordance with the spatial characteristics. An imaging device (110) is configured to image the subject in accordance with the control signals.
摘要翻译：用于自适应成像的系统和方法包括耦合到介入装置（102）以测量受试者中介入装置的空间特征的形状感测系统（115,117）。图像模块（130）被配置为接收空间特性并根据空间特性产生一个或多个控制信号。成像装置（110）被配置为根据控制信号对被摄体进行成像。

3. 发明申请

WO2011048509A1 OPTICAL SENSING - ENABLED INTERVENTIONAL INSTRUMENTS FOR RAPID DISTRIBUTED MEASUREMENTS OF BIOPHYSICAL PARAMETERS 审中-公开
标题翻译：光学感应 - 用于生物物理参数快速分布测量的传统仪器
公开(公告)号：WO2011048509A1
公开(公告)日：2011-04-28
申请号：PCT/IB2010/053845
申请日：2010-08-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , CHAN, Raymond , BARLEY, Maya, Ella , DESJARDINS, Adrien, Emmanuel , SHECHTER, Guy , 'T HOOFT, Gert
发明人： CHAN, Raymond , BARLEY, Maya, Ella , DESJARDINS, Adrien, Emmanuel , SHECHTER, Guy , 'T HOOFT, Gert
IPC分类号： A61B19/00
CPC分类号： A61B1/00165 , A61B1/005 , A61B34/20 , A61B90/06 , A61B2017/00022
摘要： An interventional instrument, system and method include an elongated flexible member (100) having one or more segmented sections (101) disposed longitudinally. An optical fiber (104) is disposed internally in the flexible member. A plurality of optical sensors (102) are coupled to the optical fiber and distributed along a length of the flexible member such that the optical sensors are positioned to monitor parameters simultaneously at different positions or at different data sources along the flexible member to provide distributed sensing.
摘要翻译：介入仪器，系统和方法包括具有纵向设置的一个或多个分段部分（101）的细长柔性构件（100）。光纤（104）设置在柔性部件的内部。多个光学传感器（102）耦合到光纤并且沿柔性部件的长度分布，使得光学传感器被定位成沿着柔性部件在不同位置或不同数据源处同时监测参数以提供分布式感测。

4. 发明申请

WO2011033421A1 MEDICAL ULTRASOUND DEVICE WITH FORCE DETECTION 审中-公开
标题翻译：具有强力检测功能的医用超声波装置
公开(公告)号：WO2011033421A1
公开(公告)日：2011-03-24
申请号：PCT/IB2010/054048
申请日：2010-09-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , BARLEY, Maya, Ella , HARKS, Godefridus, Antonius , DELADI, Szabolcs
发明人： BARLEY, Maya, Ella , HARKS, Godefridus, Antonius , DELADI, Szabolcs
IPC分类号： A61B19/00 , A61B8/12 , A61B18/02 , A61B18/12
CPC分类号： A61B90/06 , A61B5/6885 , A61B8/12 , A61B8/445 , A61B18/0206 , A61B18/12 , A61B18/1492 , A61B2017/00106 , A61B2090/065
摘要： A medical ultrasound device is disclosed. The device comprises an elongated body having a proximal end and a distal end region (1). One or more ultrasound transducers (4) for generating acoustic radiation are positioned in the distal end region, inside the elongated body. A transmission element (5) which is substantially transparent to acoustic radiation is positioned in the radiation path of the acoustic radiation, and a controller unit is operatively connected to the ultrasound transducer. The transmission element and the one or more ultrasound transducers are mounted so that an acoustic path length (8) between the transmission element (5) and the ultrasound transducer (4) varies with contact force (10) imposed to the distal end region. The controller unit detects the acoustic path length between the ultrasound transducer and the transmission element and determines the contact force from the detected acoustic path length. In an embodiment, the medical device is an ultrasound RF ablation catheter.
摘要翻译：公开了一种医用超声波装置。该装置包括具有近端和远端区域（1）的细长主体。用于产生声辐射的一个或多个超声换能器（4）位于细长体内的远端区域。对声辐射基本透明的传输元件（5）位于声辐射的辐射路径中，并且控制器单元可操作地连接到超声换能器。传输元件和一个或多个超声波换能器被安装成使得传输元件（5）和超声换能器（4）之间的声学路径长度（8）随施加到远端区域的接触力（10）而变化。控制器单元检测超声换能器和传动元件之间的声路长度，并根据检测到的声道长度确定接触力。在一个实施例中，医疗装置是超声RF消融导管。

5. 发明申请

WO2012168826A3 ROTATIONAL POSITION DETERMINATION APPARATUS 审中-公开
公开(公告)号：WO2012168826A3
公开(公告)日：2012-12-13
申请号：PCT/IB2012/052679
申请日：2012-05-29
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , ALVES DE INDA, Márcia , VAN DER LINDEN, Wilhelmus, Petrus, Maria , BARLEY, Maya, Ella , RADAELLI, Alessandro, Guido
发明人： ALVES DE INDA, Márcia , VAN DER LINDEN, Wilhelmus, Petrus, Maria , BARLEY, Maya, Ella , RADAELLI, Alessandro, Guido
IPC分类号： A61B19/00
摘要： The invention relates to a rotational position determination apparatus (15) for determining an entry rotational position, which defines a rotational position of an insertion device like a stent at an entry site (5), such that a navigation of the insertion device from the entry site to a target site (6) along an inner path (8) results in a rotational position of the insertion device at the target site being equal to a desired target rotational position based on a representation of the inner path and the desired target rotational position. If the insertion device is arranged in the determined entry rotational position at the entry site and then navigated to the target site, it is therefore not necessary to rotate the insertion device at the target site, i.e. it is not necessary to use a technically complex interventional device for rotating the insertion device at the target site.

6. 发明申请

WO2012042413A1 DETECTION OF BIFURCATIONS USING TRACEABLE IMAGING DEVICE AND IMAGING TOOL 审中-公开
标题翻译：使用可追溯成像装置和成像工具检测瑕疵
公开(公告)号：WO2012042413A1
公开(公告)日：2012-04-05
申请号：PCT/IB2011/053952
申请日：2011-09-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , DELADI, Szabolcs , BARLEY, Maya, Ella , BAKKER, Nicolaas, Hylke , BABIC, Drazenko
发明人： DELADI, Szabolcs , BARLEY, Maya, Ella , BAKKER, Nicolaas, Hylke , BABIC, Drazenko
IPC分类号： A61B8/12 , A61B8/08 , A61B19/00 , A61B5/06 , A61B6/12
CPC分类号： A61B8/4254 , A61B5/066 , A61B5/489 , A61B6/12 , A61B8/085 , A61B8/0891 , A61B8/12 , A61B8/445 , A61B34/20 , A61B2034/2051 , A61B2090/378
摘要： A system, device and method include an interventional device (106) including one or more ultrasonic transducers (108) configured to generate a signal to indicate presence of a branch or bifurcation of a lumen inside a subject. A localization system (102) is configured to track the interventional device in the subject. A program module (122) is implemented by a processor to compare a position of the interventional device against a reference image (130) and to indicate the presence of the branch or bifurcation relative to the position in accordance with the signal.
摘要翻译：系统，装置和方法包括介入装置（106），其包括一个或多个超声波换能器（108），其构造成产生信号以指示对象内的管腔的分支或分叉的存在。定位系统（102）被配置为跟踪被摄体中的介入装置。程序模块（122）由处理器实现，以将介入装置的位置与参考图像（130）进行比较，并根据该信号指示相对于该位置的分支或分支的存在。

7. 发明申请

WO2011095937A1 COMBINED ABLATION AND ULTRASOUND IMAGING 审中-公开
标题翻译：组合吸收和超声成像
公开(公告)号：WO2011095937A1
公开(公告)日：2011-08-11
申请号：PCT/IB2011/050462
申请日：2011-02-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , HARKS, Godefridus, Antonius , DELADI, Szabolcs , SUIJVER, Jan, Frederik , BARLEY, Maya, Ella , BONGERS, Edwin, Gerardus, Johannus, Maria
发明人： HARKS, Godefridus, Antonius , DELADI, Szabolcs , SUIJVER, Jan, Frederik , BARLEY, Maya, Ella , BONGERS, Edwin, Gerardus, Johannus, Maria
IPC分类号： A61B18/18 , A61B18/14 , A61B17/00 , A61B18/00 , A61N7/02 , A61N5/04 , A61B18/20
CPC分类号： A61B18/18 , A61B17/3478 , A61B18/04 , A61B18/1206 , A61B18/1477 , A61B18/1492 , A61B18/1815 , A61B18/20 , A61B18/24 , A61B2017/00106 , A61B2018/00029 , A61B2018/00351 , A61B2018/00642 , A61B2018/00666 , A61B2018/00875 , A61B2018/1425 , A61B2018/1861 , A61B2018/1869 , A61B2090/064 , A61B2090/3784 , A61B2218/002
摘要： The present invention relates to a system (100) for combined ablation and ultrasound imaging of associated tissue (40), which is particularly useful for use in an ablation process. The system comprises an interventional device (20) with an ultrasound transducer and an ablation unit. During an ablation process, the interventional device (20) can be applied for both ablation and imaging of the tissue (40) subject to the ablation. A controlling unit (CTRL) is further comprised within the system, and arranged to calculate a predictor value based on one or more signals from the ultrasound transducer, where the predictor value relates to a risk of impending tissue damage due to a rapid release of bubble energy. According to a specific embodiment, a primary signal is sent if the predictor value exceeds a threshold value, so that proper measures can be taken.
摘要翻译：本发明涉及用于相关组织（40）的组合消融和超声成像的系统（100），其特别适用于消融过程。该系统包括具有超声换能器和消融单元的介入装置（20）。在消融过程期间，介入装置（20）可以应用于经受消融的组织（40）的消融和成像。控制单元（CTRL）还包括在系统内，并且被布置为基于来自超声换能器的一个或多个信号来计算预测值，其中预测值与由于气泡的快速释放引起的组织损伤的风险相关能源。根据具体实施例，如果预测值超过阈值，则发送主信号，从而可以采取适当的措施。

8. 发明公开

EP2490612A1 OPTICAL SENSING - ENABLED INTERVENTIONAL INSTRUMENTS FOR RAPID DISTRIBUTED MEASUREMENTS OF BIOPHYSICAL PARAMETERS 审中-公开
标题翻译：用于快速光学扫描适合...介入性器械分布参数生物物理测量
公开(公告)号：EP2490612A1
公开(公告)日：2012-08-29
申请号：EP10760016.5
申请日：2010-08-26
申请人： Koninklijke Philips Electronics N.V.
发明人： CHAN, Raymond , BARLEY, Maya, Ella , DESJARDINS, Adrien, Emmanuel , SHECHTER, Guy , 'T HOOFT, Gert
IPC分类号： A61B19/00
CPC分类号： A61B1/00165 , A61B1/005 , A61B34/20 , A61B90/06 , A61B2017/00022
摘要： An interventional instrument, system and method include an elongated flexible member (100) having one or more segmented sections (101) disposed longitudinally. An optical fiber (104) is disposed internally in the flexible member. A plurality of optical sensors (102) are coupled to the optical fiber and distributed along a length of the flexible member such that the optical sensors are positioned to monitor parameters simultaneously at different positions or at different data sources along the flexible member to provide distributed sensing.
摘要翻译：的介入器械，系统和方法，包括在具有一个或多个分段部分（101）的纵向设置的长形柔性构件（100）。一种光纤（104）设置在所述柔性构件内部地设置。光学传感器中的多个（102）被耦合到所述光纤，并沿着检查没有所述光学传感器被设置成在不同的位置或在沿所述柔性构件，以提供分布式感测不同的数据源同时监控参数的柔性构件的长度分布，

9. 发明公开

EP2632384A1 ADAPTIVE IMAGING AND FRAME RATE OPTIMIZING BASED ON REAL-TIME SHAPE SENSING OF MEDICAL INSTRUMENTS 有权转让
标题翻译：自适应成像和图像费用的优化根据医疗仪器实时形状取得
公开(公告)号：EP2632384A1
公开(公告)日：2013-09-04
申请号：EP11785482.8
申请日：2011-10-24
申请人： Koninklijke Philips Electronics N.V.
发明人： CHAN, Raymond , WANG, Jinnan , DESJARDINS, Adrien, Emmanuel , GUTIERREZ, Luis, Felipe , BARLEY, Maya, Ella , 't HOOFT, Gert, Wim
IPC分类号： A61B19/00
CPC分类号： A61B6/488 , A61B5/055 , A61B5/066 , A61B6/03 , A61B6/12 , A61B6/486 , A61B6/487 , A61B6/504 , A61B6/5229 , A61B6/54 , A61B6/542 , A61B34/20 , A61B2017/00075 , A61B2034/2051 , A61B2034/2061
摘要： A system and method for adaptive imaging include a shape sensing system (115, 117) coupled to an interventional device (102) to measure spatial characteristics of the interventional device in a subject. An image module (130) is configured to receive the spatial characteristics and generate one or more control signals in accordance with the spatial characteristics. An imaging device (110) is configured to image the subject in accordance with the control signals.
摘要翻译：一种用于自适应成像系统和方法包括连接到在介入设备（102）的形状感测系统（115，117），以测量在受试者的介入装置的空间特性。图像模块（130）被配置成与所述空间特性接收的空间特性，并产生在雅舞蹈的一个或多个控制信号。一种成像设备（110）被配置为图像与所述控制信号在雅舞蹈的主题。

10. 发明授权

EP2477572B1 MEDICAL ULTRASOUND DEVICE WITH FORCE DETECTION 有权转让
标题翻译：与功率检测医疗超声设备
公开(公告)号：EP2477572B1
公开(公告)日：2013-01-16
申请号：EP10760063.7
申请日：2010-09-08
申请人： Koninklijke Philips Electronics N.V.
发明人： BARLEY, Maya, Ella , HARKS, Godefridus, Antonius , DELADI, Szabolcs
IPC分类号： A61B19/00 , A61B8/12 , A61B18/02 , A61B18/12
CPC分类号： A61B90/06 , A61B5/6885 , A61B8/12 , A61B8/445 , A61B18/0206 , A61B18/12 , A61B18/1492 , A61B2017/00106 , A61B2090/065

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