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81. 发明申请

US20050131511A1 Cardiac lead having coated fixation arrangement 有权
标题翻译：心脏导联具有涂层固定布置
公开(公告)号：US20050131511A1
公开(公告)日：2005-06-16
申请号：US10733868
申请日：2003-12-11
申请人： Randy Westlund
发明人： Randy Westlund
IPC分类号： A61N1/05
CPC分类号： A61N1/0587 , A61N1/0573
摘要： Implantable cardiac monitoring and stimulation devices and methods using cardiac leads employ coated fixation arrangements. The coating, such as an expanded polytetrafluoroethylene, reduces exit block by reducing the tissue response to the fixation arrangement, decreasing the amount of fibrotic tissue, and reducing exit block. An epicardial lead may include a lead body with one or more electrical conductors with associated insulators and an electrode assembly situated at the distal end. The electrode assembly includes an electrode having an active fixation arrangement such as a helical fixation element. The fixation arrangement is completely or partially coated with a fluoropolymer or has a sleeve on some or all of the active fixation arrangement. The coating or sleeve may include a steroid or other pharmacological eluting arrangement disposed on the active fixation arrangement.
摘要翻译：使用心脏引线的植入式心脏监测和刺激装置和方法采用涂覆固定装置。涂层，例如膨胀的聚四氟乙烯，通过减少对固定装置的组织反应，减少纤维组织的量和减少出口块来减少出口块。心外膜引线可以包括具有一个或多个具有相关绝缘体的电导体的引线体和位于远端的电极组件。电极组件包括具有主动固定装置的电极，例如螺旋固定元件。固定装置完全或部分地涂覆有氟聚合物，或者在一些或全部活性固定装置上具有套筒。涂层或套管可以包括设置在主动固定装置上的类固醇或其它药理学洗脱布置。

82. 发明申请

US20050113901A1 Myocardial lead attachment system 审中-公开
标题翻译：心肌引导附件系统
公开(公告)号：US20050113901A1
公开(公告)日：2005-05-26
申请号：US10971551
申请日：2004-10-22
申请人： M. Sean Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme , Charles Gresl
发明人： M. Sean Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme , Charles Gresl
IPC分类号： A61B5/0492 , A61B17/04 , A61B17/06 , A61N1/05
CPC分类号： A61B17/0469 , A61B5/0492 , A61B17/06109 , A61B2017/0417 , A61B2017/06042 , A61B2017/0608 , A61N1/0568 , A61N1/0587 , A61N2001/0578 , A61N2001/058
摘要： The present invention is a myocardial lead attachment system for securing a distal end of a lead within a myocardium of a patient's heart. The system includes an anchor, a tether coupled to the anchor, and a delivery instrument for receiving and advancing the anchor through a tract in the heart from a proximal entrance site to a distal exit site in such a manner that the tether extends proximally from the anchor through the tract. The delivery instrument includes a needle having a distal tip and a nest. The nest is positioned proximal to the distal tip and is sized to receive the anchor. The delivery instrument further includes an ejection mechanism for ejecting the anchor from the nest.
摘要翻译：本发明是用于将铅的远端固定在患者心脏的心肌内的心肌引导附着系统。所述系统包括锚固件，联接到所述锚固件的系绳和用于接收并推进所述锚固件穿过所述心脏中的管道从近侧入口部位到远端出口部位的方式的系统，所述系绳以从所述锚固件的方式向近侧延伸锚通过道。递送器械包括具有远端和窝的针。巢定位在远侧末端附近，并且其尺寸被设计成接收锚。输送仪器还包括用于从座中弹出锚固件的弹出机构。

83. 发明授权

US6033414A Torque device for left ventricular lead systems 失效
标题翻译：用于左心室引导系统的扭矩装置
公开(公告)号：US6033414A
公开(公告)日：2000-03-07
申请号：US100164
申请日：1998-06-18
申请人： Bruce A. Tockman , Randy Westlund
发明人： Bruce A. Tockman , Randy Westlund
IPC分类号： A61B17/00 , A61N1/05 , A61N1/36
CPC分类号： A61N1/057 , A61B2017/00469 , A61M25/09041 , A61N2001/0578
摘要： The present invention is a torque handle for use in inserting and positioning a pacing lead and guide wire, such as within a coronary vein. The torque handle is a handle with a lumen extending therethrough. A first clamping arrangement is located on the handle and receives the guide wire therethrough. A second clamping arrangement is also located on the handle. The second clamping arrangement sized to receive the body of the lead therethrough. In use, the physician determines whether torque is to be transmitted along the lead, the guide wire or both. Torque is transmitted by clamping or loosening the designated clamping arrangement around the lead, the guide wire or both, and then rotating the handle. As the handle is rotated, torque is transmitted along the length of the clamped lead or guide wire or both.
摘要翻译：本发明是用于插入和定位起搏引线和导丝（例如在冠状静脉内）的扭矩手柄。扭矩手柄是具有延伸穿过其中的内腔的把手。第一夹紧装置位于手柄上并且接纳穿过其中的导丝。第二夹紧装置也位于手柄上。第二夹紧装置的尺寸被设计成接纳引线的主体。在使用中，医师确定扭矩是否沿着引线，导丝或两者传递。通过夹紧或松开围绕引线，导丝或两者的指定的夹紧装置，然后旋转手柄来传递扭矩。当手柄旋转时，扭矩沿着夹紧的导线或导丝的长度或两者传递。

84. 发明授权

US08369943B2 Method and apparatus for neural stimulation via the lymphatic system 有权
标题翻译：通过淋巴系统进行神经刺激的方法和装置
公开(公告)号：US08369943B2
公开(公告)日：2013-02-05
申请号：US12604233
申请日：2009-10-22
申请人： Allan C. Shuros , Randy Westlund , Anthony V. Caparso
发明人： Allan C. Shuros , Randy Westlund , Anthony V. Caparso
IPC分类号： A61N1/34
CPC分类号： A61N1/36114
摘要： An implantable neural stimulation system includes an implantable medical device having a neural stimulation circuit and at least one implantable lead configured to allow one or more stimulation electrodes to be placed in one or more lymphatic vessels of a patient, such as the patient's thoracic duct and/or vessels branching from the thoracic duct. Neural stimulation pulses are delivered from the implantable medical device to one or more target regions adjacent to the thoracic duct or the vessels branching from the thoracic duct through the one or more stimulation electrodes.
摘要翻译：可植入神经刺激系统包括具有神经刺激电路的可植入医疗装置和至少一个可植入引线，其被配置为允许将一个或多个刺激电极放置在患者的一个或多个淋巴管中，例如患者的胸导管和/ 或从胸导管分支的血管。神经刺激脉冲从可植入医疗装置传送到与胸导管相邻的一个或多个目标区域或通过一个或多个刺激电极从胸导管分支的血管。

85. 发明授权

US08290584B2 Method and apparatus for optimizing vagal nerve stimulation using laryngeal activity 有权
标题翻译：使用喉部活动优化迷走神经刺激的方法和装置
公开(公告)号：US08290584B2
公开(公告)日：2012-10-16
申请号：US12872408
申请日：2010-08-31
申请人： Randy Westlund , Anthony V. Caparso , Mark Bly
发明人： Randy Westlund , Anthony V. Caparso , Mark Bly
IPC分类号： A61N1/36
CPC分类号： A61N1/36053 , A61B5/04001 , A61B5/0402 , A61B5/1104 , A61B5/6822 , A61B5/7203 , A61N1/0551 , A61N1/36114 , A61N1/36542 , A61N1/37247 , A61N1/37288
摘要： A neural stimulation system delivers neural stimulation to the vagus nerve and senses a signal indicative of laryngeal activity resulting from the neural stimulation. The signal indicative of laryngeal activity is used, for example, to guide electrode placement, determine stimulation threshold, detect lead/electrode problems, detect neural injury, and monitor healing processing following the electrode placement inside the body of a patient.
摘要翻译：神经刺激系统将神经刺激传递给迷走神经，并感测到指示由神经刺激引起的喉部活动的信号。例如，使用指示喉部活动的信号来引导电极放置，确定刺激阈值，检测铅/电极问题，检测神经损伤，以及在患者体内的电极放置之后监测愈合过程。

86. 发明申请

US20120078333A1 MEDICAL LEAD SYSTEM UTILIZING ELECTROMAGNETIC BANDSTOP FILTERS 有权
标题翻译：医用铅系统利用电磁带式过滤器
公开(公告)号：US20120078333A1
公开(公告)日：2012-03-29
申请号：US13312741
申请日：2011-12-06
申请人： Randy Westlund , Robert A. Stevenson , Christine A. Frysz , Warren S. Dabney , Henry R. Halperin
发明人： Randy Westlund , Robert A. Stevenson , Christine A. Frysz , Warren S. Dabney , Henry R. Halperin
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0534 , A61N1/0539 , A61N1/0556 , A61N1/0587 , A61N1/086 , A61N2001/0585 , H03H1/0007 , H03H2001/0042 , H03H2001/005 , H03H2007/013
摘要： Medical lead systems utilizing electromagnetic bandstop filters are provide which can be utilized in a magnetic resonance imaging (MRI) environment for patients who have implanted medical devices. The medical lead system includes an implanted lead having at least one bandstop filter associated therewith, for attenuating current flow through the lead over a range of frequencies. The bandstop filter has an overall circuit Q wherein the resultant 3 dB bandwidth is at least 10 kHz. The values of capacitance and inductance of the bandstop filter are selected such that the bandstop filter is resonant at a selected center frequency. Preferably, the bandstop filter has an overall circuit Q wherein the resultant 10 dB bandwidth is at least 10 kHz. Such bandstop filters are backwards compatible with known implantable deployment systems and extraction systems.
摘要翻译：提供利用电磁带阻滤波器的医疗引线系统，其可用于已经植入医疗装置的患者的磁共振成像（MRI）环境中。医疗引线系统包括具有与其相关联的至少一个带阻滤波器的植入引线，用于在一定频率范围内衰减通过引线的电流。带阻滤波器具有总电路Q，其中所得的3dB带宽至少为10kHz。选择带阻滤波器的电容和电感值，使得带阻滤波器在选定的中心频率处谐振。优选地，带阻滤波器具有总电路Q，其中所得的10dB带宽至少为10kHz。这种带阻滤波器与已知的可植入部署系统和提取系统向后兼容。

87. 发明授权

US08126538B2 Method and apparatus for introducing endolymphatic instrumentation 有权
标题翻译：用于引入内淋巴仪的方法和装置
公开(公告)号：US08126538B2
公开(公告)日：2012-02-28
申请号：US11422423
申请日：2006-06-06
申请人： Allan C. Shuros , Randy Westlund , M. Jason Brooke
发明人： Allan C. Shuros , Randy Westlund , M. Jason Brooke
IPC分类号： A61B5/05
CPC分类号： A61N1/362 , A61B5/0031 , A61B5/0452 , A61B5/415 , A61B5/418 , A61M2202/0405 , A61N1/0504
摘要： Described herein are a method and apparatus for introducing instrumentation into the lymphatic system that can be used for physiological monitoring and/or delivery of therapy. Such instrumentation, for example, may include one or more sensors for measuring physiological variables and/or one or more instruments for delivering therapy that is adapted to be disposed within a lymphatic vessel.
摘要翻译：本文描述了用于将仪器引入淋巴系统中的方法和装置，其可用于治疗的生理监测和/或递送。例如，这种仪器可以包括用于测量生理变量的一个或多个传感器和/或用于递送适于布置在淋巴管内的治疗的一个或多个仪器。

88. 发明授权

US08078287B2 His bundle mapping, pacing, and injection lead 有权
标题翻译：他的束映射，起搏和注射导联
公开(公告)号：US08078287B2
公开(公告)日：2011-12-13
申请号：US11760294
申请日：2007-06-08
申请人： Lili Liu , Randy Westlund , Steven D. Girouard
发明人： Lili Liu , Randy Westlund , Steven D. Girouard
IPC分类号： A61N1/05
CPC分类号： A61N1/0568
摘要： A cardiac rhythm management system includes a lead assembly for intracardiac mapping, pacing, and drug delivery. The lead assembly includes an implantable endocardial lead having a proximal end for connection to an implantable cardiac rhythm management device and a distal end for disposal in an intracardiac region. The lead includes a pacing-sensing electrode and a drug delivery device, both located at or near the distal end. A lumen is within and extends throughout the lead, with an opening at or near the proximal end and another opening at or near the distal end. The lumen provides for access to the intracardiac region by a steerable stylet and a hollow needle, one at a time. The steerable stylet allows for electrophysiological mapping of the intracardiac region. The hollow needle allows for delivery of chemical, biochemical, and/or biological substance to the intracardiac region.
摘要翻译：心律管理系统包括用于心内测绘，起搏和药物递送的导联组件。引线组件包括可植入心内膜引线，其具有用于连接到可植入心律管理装置的近端和用于在心内区域中处置的远端。引线包括起搏感测电极和药物递送装置，两者都位于远端或靠近远端。管腔在整个引线内部并且贯穿整个引线，在近端处或近端处的开口以及在远端处或附近的另一个开口。管腔通过可导向的管心针和中空针头一次一个地进入心脏内区域。可导向的管心针允许心内区域的电生理作图。中空针允许将化学，生物化学和/或生物物质递送至心内区域。

89. 发明授权

US08050775B2 Coronary vein lead having pre-formed biased portions for fixation 有权
标题翻译：冠状静脉引线具有用于固定的预先形成的偏置部分
公开(公告)号：US08050775B2
公开(公告)日：2011-11-01
申请号：US12608402
申请日：2009-10-29
申请人： Randy Westlund , Bruce A. Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce A. Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having pre-formed biased portion is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预形成偏置部分的引线适于植入在冠状脉管系统内部或周围的心脏上，并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先设定的偏压部分偏压到血管壁，该部分操作以将引线固定在血管壁上。

90. 发明授权

US07981065B2 Lead electrode incorporating extracellular matrix 有权
标题翻译：引导电极结合细胞外基质
公开(公告)号：US07981065B2
公开(公告)日：2011-07-19
申请号：US11017238
申请日：2004-12-20
申请人： Randy Westlund , Jeffrey Ross
发明人： Randy Westlund , Jeffrey Ross
IPC分类号： A61H7/00
CPC分类号： A61N1/0587 , A61N1/0575 , A61N1/059
摘要： Implantable devices containing extracellular matrix and methods of using the devices are provided.
摘要翻译：提供了含有细胞外基质的植入式装置和使用该装置的方法。

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