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1. 发明授权

US08050775B2 Coronary vein lead having pre-formed biased portions for fixation 有权
标题翻译：冠状静脉引线具有用于固定的预先形成的偏置部分
公开(公告)号：US08050775B2
公开(公告)日：2011-11-01
申请号：US12608402
申请日：2009-10-29
申请人： Randy Westlund , Bruce A. Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce A. Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having pre-formed biased portion is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预形成偏置部分的引线适于植入在冠状脉管系统内部或周围的心脏上，并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先设定的偏压部分偏压到血管壁，该部分操作以将引线固定在血管壁上。

2. 发明授权

US07628801B2 Coronary vein leads having an atraumatic tip and method therefor 有权
标题翻译：冠状静脉引导具有无创伤的尖端及其方法
公开(公告)号：US07628801B2
公开(公告)日：2009-12-08
申请号：US10128997
申请日：2002-04-23
申请人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61F7/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having an atraumatic tip is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by a preformed biased portion. Near the distal end, the lead has an optional tapered portion and a flexible portion, where the flexible portion is more flexible than the biased portion.
摘要翻译：具有无创尖端的引线适于植入在冠状脉管系统内或心脏周围并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先偏置的部分偏压到血管壁。在远端附近，引线具有可选的锥形部分和柔性部分，其中柔性部分比偏置部分更柔性。

3. 发明授权

US08498721B2 Coronary vein leads having pre-formed biased portions for fixation 有权
标题翻译：冠状静脉引导具有预先形成的用于固定的偏置部分
公开(公告)号：US08498721B2
公开(公告)日：2013-07-30
申请号：US13251466
申请日：2011-10-03
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having a pre-formed biased portion is adapted for implantation with a body vessel and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预成形的偏置部分的引线适于用身体容器注入并连接到信号发生器。引线被构造和布置成使得当其被植入时，电极通过预先形成的偏压部分朝向血管壁偏压，该部分操作以将引线固定在血管壁上。

4. 发明申请

US20120215294A1 CORONARY VEIN LEADS HAVING PRE-FORMED BIASED PORTIONS FOR FIXATION 有权
标题翻译：具有用于固定的预先形成的偏心部分的冠状动脉引导
公开(公告)号：US20120215294A1
公开(公告)日：2012-08-23
申请号：US13251466
申请日：2011-10-03
申请人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having a pre-formed biased portion is adapted for implantation with a body vessel and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预成形的偏置部分的引线适于用身体容器注入并连接到信号发生器。引线被构造和布置成使得当其被植入时，电极通过预先形成的偏压部分朝向血管壁偏压，该部分操作以将引线固定在血管壁上。

5. 发明申请

US20100049288A1 CORONARY VEIN LEAD HAVING PRE-FORMED BIASED PORTIONS FOR FIXATION 有权
标题翻译：具有用于固定的预形成偏心部分的冠状动脉引导
公开(公告)号：US20100049288A1
公开(公告)日：2010-02-25
申请号：US12608402
申请日：2009-10-29
申请人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Randy Westlund , Bruce Tockman , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having pre-formed biased portion is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预形成偏置部分的引线适于植入在冠状脉管系统内部或周围的心脏上，并用于连接到信号发生器。引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先设定的偏压部分偏压到血管壁，该部分操作以将引线固定在血管壁上。

6. 发明授权

US07890174B2 Medical electrical lead with deployable fixation features 失效
标题翻译：医用电线带有可部署的固定功能
公开(公告)号：US07890174B2
公开(公告)日：2011-02-15
申请号：US11421990
申请日：2006-06-02
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61N1/36
CPC分类号： A61N1/0573 , A61B18/1492 , A61N1/056 , A61N2001/0585
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。

7. 发明授权

US07725197B2 Medical electrical lead with friction-enhancing fixation features 有权
标题翻译：具有摩擦增强固定功能的医用电线
公开(公告)号：US07725197B2
公开(公告)日：2010-05-25
申请号：US11424349
申请日：2006-06-15
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： Medical electrical leads are provided including fixation features for acute and chronic fixation of a portion of the respective leads within the cardiac venous system. The medical electrical lead includes an elongate body having proximal and distal regions. Tissue contacting portions are selectively located in the distal region to contact an inner surface of the cardiac vessel when the lead is in an implanted position. The tissue contacting portion(s) include fixation features adapted to frictionally engage the inner surface of the cardiac vessel and promote tissue in-growth for chronic fixation. In some embodiments, the fixation features are detachable from the lead such that the lead can be extracted from its implanted position after tissue in-growth occurs.
摘要翻译：提供了医疗电引线，其包括用于心脏静脉系统内的各个引线的一部分的急性和慢性固定的固定特征。医疗电线包括具有近端和远端区域的细长体。当引线处于植入位置时，组织接触部分选择性地位于远端区域中以接触心脏血管的内表面。组织接触部分包括适于摩擦地接合心脏血管的内表面并促进用于慢性固定的组织生长的固定特征。在一些实施例中，固定特征可从铅脱离，使得在组织生长发生之后，引线可以从其植入位置提取。

8. 发明申请

US20080172118A1 LEAD WITH INFLATABLE FIXATION MECHANISM 失效
标题翻译：具有可充气的固定机构
公开(公告)号：US20080172118A1
公开(公告)日：2008-07-17
申请号：US11622810
申请日：2007-01-12
申请人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'Aquanni , Kent C. B. Stalker , Gayla A. Smith
发明人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'Aquanni , Kent C. B. Stalker , Gayla A. Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61M25/04 , A61M25/10 , A61N2001/0585
摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.
摘要翻译：构造成用于刺激心脏左侧（即，左心室）的医用电引线。在一个实施例中，引线包括包括内表面的细长引线主体。可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面，用于固定远端的铅。引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

9. 发明申请

US20070282415A1 CARDIAC LEAD HAVING IMPLANTABLE STIFFENING STRUCTURES FOR FIXATION 有权
标题翻译： CARDIAC LEAD具有可固定的强化结构用于固定
公开(公告)号：US20070282415A1
公开(公告)日：2007-12-06
申请号：US11422014
申请日：2006-06-02
申请人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C.B. Stalker , Peter J. D'aquanni , Paul E. Zarembo
发明人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C.B. Stalker , Peter J. D'aquanni , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , A61N2001/0585
摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.
摘要翻译：适于至少部分地固定在心脏血管内的心脏引线。在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。远端区域被构造成使得电极和远端尖端可以植入心脏血管。铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。在其他实施例中，加强结构包括适于部署在引线主体上的护套。在其他实施例中，加强结构与引线和/或引线主体成一体。

10. 发明授权

US08996114B2 Strain relief feature for an implantable medical device lead 有权
标题翻译：可植入医疗器械引线的应变消除功能
公开(公告)号：US08996114B2
公开(公告)日：2015-03-31
申请号：US13532314
申请日：2012-06-25
申请人： Brian D. Soltis , Bruce A. Tockman
发明人： Brian D. Soltis , Bruce A. Tockman
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： A lead assembly for an implantable medical device includes a lead body having a proximal end, a distal end, and a longitudinal axis that extends between the proximal end and distal end. The lead assembly also includes a strain relief tube that surrounds a portion of the lead body. The strain relief tube includes a flexible material configured to include contours such that the portion of the lead body surrounded by the strain relief tube maintains a formed shape that varies from the longitudinal axis of the lead body. The contours vary in response to forces on the lead body to prevent strain at the distal end of the lead body.
摘要翻译：用于可植入医疗装置的引导组件包括具有近端，远端和在近端和远端之间延伸的纵向轴线的引线体。引线组件还包括围绕引线体的一部分的应变消除管。应变消除管包括柔性材料，其被配置为包括轮廓，使得由应变消除管包围的引线体的部分保持与引线主体的纵向轴线变化的成形形状。轮廓根据引线本体上的力而变化，以防止引线主体远端处的应变。

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