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71. 发明专利

JP5164003B2 Preservation method of thin section specimen 有权
公开(公告)号：JP5164003B2
公开(公告)日：2013-03-13
申请号：JP2008064912
申请日：2008-02-15
申请人：忠文川本
发明人：忠文川本
IPC分类号： G01N1/28 , G01N1/30 , G01N33/48 , G02B21/34
CPC分类号： G01N1/36 , G01N1/42 , G01N2001/362

72. 发明专利

JP2012032238A Producing method of tissue array 审中-公开
标题翻译：组织阵列的生产方法
公开(公告)号：JP2012032238A
公开(公告)日：2012-02-16
申请号：JP2010170958
申请日：2010-07-29
申请人： Sakura Seiki Kk , サクラ精機株式会社
发明人： NAKAZAWA YOSHIAKI , TAKANO MASAKI , ARAKAWA MASAHIKO , NARITAKE KOJI
IPC分类号： G01N1/28 , G01N33/48 , G01N37/00
CPC分类号： G01N1/36 , G01N1/06 , G01N2001/362 , G01N2001/368
摘要： PROBLEM TO BE SOLVED: To provide a producing method of a tissue array capable of surely fixing even roll-shaped tissue pieces of different diameters to a block.SOLUTION: In a producing method of a tissue array that comprises a roll-shaped tissue piece 6 formed by winding sheet-like tissue piece 8 in a roll shape arranged on a base plate in an array state: a holding member 16 for holding a plurality of roll-shaped tissue pieces 6 so that axial directions of the tissue pieces 6 are oriented in a vertical direction is arranged in a container 10 in which a melted embedding agent is poured and stored; a substrate block 40 comprising the plurality of roll-shaped tissue pieces 6 arranged in the array state is formed by holding each of roll-shaped tissue pieces 6 by the holding member 16 and pouring the embedding agent into the container 10; and the tissue array is produced by slicing the substrate block 40 so that the roll-shaped tissue pieces 6 are sliced in round shape and arranging the sliced pieces on the base plate.
摘要翻译：要解决的问题：提供一种组织阵列的制造方法，其能够将均匀的不同直径的卷状组织片固定地固定在块上。解决方案：一种组织阵列的制造方法，其包括通过以排列状态将片状组织片8卷绕成布置在基板上的卷状而形成的辊状组织片6：用于保持多个辊状组织片6，使得组织片6的轴向在垂直方向上定向在其中注入和储存熔融包埋剂的容器10中; 通过用保持构件16保持各个卷状组织片6并将包埋剂倒入容器10而形成包括排列成阵列状态的多个卷状组织片6的基板块40。并且通过对基板块40进行切片来制造组织阵列，使得将卷状的组织片6切成圆形，并将切片排列在基板上。版权所有（C）2012，JPO＆INPIT

73. 发明专利

JP2008233080A Method for preservation of thin section specimen 有权
标题翻译：保护薄片部分样本的方法
公开(公告)号：JP2008233080A
公开(公告)日：2008-10-02
申请号：JP2008064912
申请日：2008-02-15
申请人： Tadafumi Kawamoto , 忠文川本
发明人： KAWAMOTO TADAFUMI
IPC分类号： G01N1/28 , G01N1/30 , G01N33/48 , G02B21/34
CPC分类号： G01N1/36 , G01N1/42 , G01N2001/362
摘要： PROBLEM TO BE SOLVED: To stain a thin section produced from a frozen embedded sample by using an adhesive plastic film as a support material for the thin section in a state attached to the adhesive plastic film, and thereafter enclose and preserve it in the form attached to the adhesive plastic film as a permanent specimen that can be observed by an optical microscope.
SOLUTION: The thin section having a maintained shape is produced by using an adhesive plastic film having a strong adhesion even at a lower temperature (e.g., -25°C). Subsequently, the thin section is stained in a state attached to the adhesive plastic film, and thereafter impregnated with a water-soluble resin which can be polymerized and cured by light irradiation or heating, thereafter the specimen is fitted tightly to a glass plate having the same resin applied thereto, then the water-soluble resin is polymerized and cured by light irradiation or heating, and the thin section is enclosed and preserved between the adhesive plastic film and the glass plate as a permanent specimen.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：通过使用粘合塑料膜作为连接到粘合塑料膜的状态的薄部分的支撑材料来染色由冷冻的嵌入样品产生的薄部分，然后将其包围并保存在附着在粘合塑料膜上的形式作为可以通过光学显微镜观察的永久标本。解决方案：具有保持形状的薄部分通过使用即使在较低温度（例如-25℃）下具有强粘合力的粘合塑料膜来制造。随后，将薄片以粘附塑料薄膜的状态进行染色，然后用能够通过光照射或加热聚合固化的水溶性树脂进行浸渍，然后将样品紧紧地装配到具有施加相同的树脂，然后通过光照射或加热使水溶性树脂聚合和固化，并且将薄片封闭并保存在粘合塑料膜和玻璃板之间作为永久标本。版权所有（C）2009，JPO＆INPIT

74. 发明专利

JP4153496B2 Processing container sections sample processing method of the slice sample, and sections sample processing device 有权
公开(公告)号：JP4153496B2
公开(公告)日：2008-09-24
申请号：JP2005029318
申请日：2005-02-04
申请人：セイコーインスツル株式会社
发明人：哲雅伊藤 , 竜也宮谷
IPC分类号： G01N1/30 , G01N1/06 , G01N33/48
CPC分类号： G01N1/06 , B01L3/50855 , B01L2300/0812 , G01N1/2813 , G01N35/00009 , G01N2001/2833 , G01N2001/362
摘要： The container comprises a cylindrical member 20 which constitutes the side wall member, a bottom member 30 which is in contact with the bottom plane of the cylindrical member 20 and which constitutes the bottom part, and an engaged fixing part 35 for engaging the cylindrical member 20 with the bottom member 30; the cylindrical member 20 and the bottom member 30 sandwiches the carrier tape T from one side T1 of the carrier tape T and from the other side T2 of the carrier tape T, respectively, such that one of the plural thin section samples P1 may be disposed inside the cylindrical member 20. Accordingly, without cutting a sequence of tapes carrying thereon the thin section samples of biomedical tissues, each of the thin section samples of the biomedical tissues can be individually processed with different chemicals depending on the required observation for various types of biomedical tissues.

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