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    • 9. 发明申请
    • Tissue Sample Preprocessing Methods and Devices
    • 组织样品预处理方法和装置
    • US20090215112A1
    • 2009-08-27
    • US12389154
    • 2009-02-19
    • Eswar Prasad Ramachandran IyerDaniel N. Cox
    • Eswar Prasad Ramachandran IyerDaniel N. Cox
    • G01N33/48C12M1/00
    • G01N1/36C12M45/02G01N2001/362
    • To preprocess a tissue sample, a first permeable mesh membrane is tautly stretched out over the tissue sample and overlaid on top of a flat surface. This covering sandwiches and secures the tissue sample in between the first permeable mesh membrane and the flat surface. If it is desired to reinforce the mechanical strength of the first permeable mesh membrane, a second permeable mesh membrane can be tautly stretched out and overlaid on top of the sandwich. Alternatively, the second permeable mesh membrane can be attached onto a third component, such as a disposable solvent resistant frame, to create a framed mesh. Thereafter, the first permeable mesh membrane may be attached to the framed mesh to create a compound framed mesh. The tissue sample may then be sandwiched and secured in between the compound framed mesh and the flat surface. To retain and flatten the tissue sample, gentle pressure may be uniformly applied.
    • 为了预处理组织样品,将第一可渗透网膜张紧地伸展到组织样品上并覆盖在平坦表面的顶部上。 这种覆盖三明治并将组织样品固定在第一可渗透网膜和平坦表面之间。 如果希望增强第一可渗透网膜的机械强度,则可以将第二可渗透网膜张紧地拉伸并覆盖在夹层的顶部上。 或者,第二可渗透网膜可以附接到第三部件,例如一次性耐溶剂框架上,以形成框架网。 此后,第一可渗透网膜可以附接到框架网以产生复合框架网。 然后可以将组织样品夹在并固定在复合框架网和平坦表面之间。 为了保持和平坦化组织样品,可以均匀地施加温和的压力。