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71. 发明申请

US20070216909A1 Methods for mapping tissue with optical coherence tomography data 有权
标题翻译：用光学相干断层扫描数据绘制组织的方法
公开(公告)号：US20070216909A1
公开(公告)日：2007-09-20
申请号：US11717263
申请日：2007-03-13
申请人： Matthew Everett , Paul Stetson , Scott Meyer , Shahram Dastmalchi , Jochen Straub
发明人： Matthew Everett , Paul Stetson , Scott Meyer , Shahram Dastmalchi , Jochen Straub
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： A61B3/10 , A61B3/00 , A61B3/102 , A61B5/0059 , A61B5/0066 , G01B9/02048 , G01B9/02089 , G01B9/02091 , G01N21/4795 , G06F19/00
摘要： Various methods are disclosed for mapping optical coherence tomography (OCT) data to facilitate review and diagnosis. In one aspect, high resolution 2D line scans are obtained along with lower density 3D cube scans and displayed in a manner to provide context to the clinician. In another aspect, OCT data is analyzed to provide information about non-uniformities of the tissue. Binary image maps of maps useful for determining tautness of membranes are also disclosed.
摘要翻译：公开了各种用于映射光学相干断层扫描（OCT）数据的方法以便于检查和诊断。在一个方面，获得高分辨率2D线扫描以及较低密度的3D立方体扫描，并以向临床医生提供上下文的方式显示。在另一方面，分析OCT数据以提供关于组织的非均匀性的信息。还公开了可用于确定膜紧张度的地图的二进制图像映射。

72. 发明申请

US20070152225A1 Optical broadband emitters and methods of making the same 失效
标题翻译：光纤宽带发射器及其制作方法
公开(公告)号：US20070152225A1
公开(公告)日：2007-07-05
申请号：US11322814
申请日：2005-12-29
申请人： Boon-Siew Ooi , Hery Djie , Yan Zhou , Scott Meyer
发明人： Boon-Siew Ooi , Hery Djie , Yan Zhou , Scott Meyer
IPC分类号： H01L29/15
CPC分类号： H01L33/0045 , B82Y20/00 , H01S5/026 , H01S5/0425 , H01S5/0602 , H01S5/22 , H01S5/34313 , H01S5/4031 , H01S5/50 , H01S2301/02 , H01S2301/04
摘要： An optical broadband emitter and the method of making such a broadband emitter are described. Intermixing of closely coupled multiple quantum wells, especially carrier tunneled coupled quantum wells, is described using nano-imprinting of a gel like dielectric layer such as a sol-gel derived SiO2 layer into multiple stepped or graded sections to form intermixing cap regions of different thickness. A thermal annealing process is performed to condense the SiO2 intermixing cap and induce intermixing. A superluminescent diode is described having multiple electrodes deposited over multiple sections of different bandgaps in which each individual electrode can be either forward or reverse biased to different degrees such that each diode section can individually function as a sub-band spontaneous emitter, an amplifier/attenuator, a photon-absorber, a transparent waveguide, or a photodetector/optical power monitor.
摘要翻译：描述了光学宽带发射器和制造这种宽带发射器的方法。使用诸如溶胶 - 凝胶衍生的SiO 2层之类的凝胶状电介质层将多个步进或分级部分的纳米压印描述为紧密耦合的多个量子阱，特别是载流子隧道耦合量子阱的混合以形成不同厚度的混合盖区域。进行热退火处理以冷凝SiO 2混合盖并引发混合。描述了一种超发光二极管，其具有沉积在不同带隙的多个部分上的多个电极，其中每个单独的电极可以被正向或反向偏置到不同的程度，使得每个二极管部分可以单独地用作子带自发发射极，放大器/衰减器光子吸收器，透明波导或光电检测器/光功率监视器。

73. 发明申请

US20070150011A1 Neural stimulation system for reducing atrial proarrhythmia 有权
标题翻译：用于减少心房心律失常的神经刺激系统
公开(公告)号：US20070150011A1
公开(公告)日：2007-06-28
申请号：US11320173
申请日：2005-12-28
申请人： Scott Meyer , Alok Sathaye
发明人： Scott Meyer , Alok Sathaye
IPC分类号： A61N1/36
CPC分类号： A61N1/3702 , A61N1/36114 , A61N1/3624
摘要： A system for reducing proarrhythmic effects of neural stimulation is provided. One aspect of this disclosure relates to an implantable medical device (IMD) for reducing proarrhythmic effects of neural stimulation. The IMD includes a neural stimulator adapted to deliver an electrical signal through at least one electrode to provide vagal stimulation. The IMD also includes a controller adapted to receive atrial arrhythmia vulnerability data and to control a therapeutic stimulator to limit atrial proarrhythmia using the atrial arrhythmia vulnerability data. The controller is further adapted to receive atrial arrhythmic history data and to control a therapeutic stimulator to limit atrial proarrhythmia using the atrial arrhythmic history data, according to various embodiments. According to one embodiment, the therapeutic stimulator includes the neural stimulator. The therapeutic stimulator includes a cardiac stimulator adapted to provide cardiac rhythm management therapy, according to various embodiments. Other aspects and embodiments are provided herein.
摘要翻译：提供了减少神经刺激的心律失常作用的系统。本公开的一个方面涉及用于减少神经刺激的心律失常作用的可植入医疗装置（IMD）。 IMD包括适于通过至少一个电极传递电信号以提供迷走神经刺激的神经刺激器。 IMD还包括一个控制器，适用于接收心房心律失常的脆弱性数据，并使用房性心律失常漏洞数据来控制治疗性刺激器来限制心房心律失常。根据各种实施例，控制器还适于接收心房心律失常历史数据并且使用心房心律不齐历史数据来控制治疗性刺激器来限制心房心律失常。根据一个实施例，治疗刺激器包括神经刺激器。根据各种实施例，治疗性刺激器包括适于提供心律控制治疗的心脏刺激器。本文提供了其它方面和实施例。

74. 发明申请

US20070016261A1 Multi channel approach to capture verification 失效
标题翻译：捕获验证的多渠道方法
公开(公告)号：US20070016261A1
公开(公告)日：2007-01-18
申请号：US11180937
申请日：2005-07-12
申请人： Yanting Dong , Scott Meyer , Qingsheng Zhu
发明人： Yanting Dong , Scott Meyer , Qingsheng Zhu
IPC分类号： A61N1/00
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/7217 , A61B5/7264
摘要： Methods and systems involve classifying the cardiac response to pacing using a multi-channel approach. Multiple cardiac response signals are sensed via multiple sense channels. Each sense channel comprises a distinct combination of electrodes and sensing circuitry. The cardiac response to the pacing pulse is classified based on the morphology of the cardiac response signals. Classifying the cardiac response involves discriminating between capture, fusion, non-capture, and non-capture with intrinsic activity.
摘要翻译：方法和系统包括使用多通道方法对心脏起搏应答进行分类。通过多个感测通道感测多个心脏反应信号。每个感测通道包括电极和感测电路的不同组合。基于心脏反应信号的形态对起搏脉搏的心脏反应进行分类。分类心脏反应包括区分捕获，融合，非捕获和非捕获与内在活动。

75. 发明申请

US20060253162A1 Closed loop cardiac resynchronization therapy using cardiac activation sequence information 有权
标题翻译：闭环心脏再同步治疗使用心脏激活序列信息
公开(公告)号：US20060253162A1
公开(公告)日：2006-11-09
申请号：US11125068
申请日：2005-05-09
申请人： Yi Zhang , Yinghong Yu , Aaron McCabe , Jiang Ding , Jeffrey Stahmann , Carlos Ricci , Scott Meyer
发明人： Yi Zhang , Yinghong Yu , Aaron McCabe , Jiang Ding , Jeffrey Stahmann , Carlos Ricci , Scott Meyer
IPC分类号： A61N1/365
CPC分类号： A61N1/3712 , A61N1/3627 , A61N1/365 , G06F19/00
摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.
摘要翻译：提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。心脏信号分离用于使用心脏激活序列信息来检测，监测，跟踪和/或趋势闭环心脏再同步治疗。设备和方法包括使用多个电极感测多个复合心脏信号，所述电极被配置用于植入患者体内。使用所感测的多个复合心脏信号进行源分离，产生与一个或多个心脏激活序列的全部或一部分相关联的一个或多个心脏信号载体。使用一个或多个心脏信号向量和与一个或多个心脏信号载体相关联的信号中的一个或两个来调整心脏再同步治疗。在另外的实施方案中，心脏再同步治疗可以被启动，终止，或者可以改变再同步治疗的一个或多个参数。

76. 发明申请

US20060253044A1 Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes 有权
标题翻译：使用从多个植入电极感测的心电图的心律失常辨别
公开(公告)号：US20060253044A1
公开(公告)日：2006-11-09
申请号：US11125020
申请日：2005-05-09
申请人： Yi Zhang , Carlos Ricci , Jeffrey Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
发明人： Yi Zhang , Carlos Ricci , Jeffrey Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
IPC分类号： A61B5/04
CPC分类号： A61B5/04011 , A61B5/7203
摘要： Cardiac monitoring and/or stimulation methods and systems provide for monitoring, diagnosing, defibrillation and pacing therapies, or a combination of these capabilities, including cardiac systems incorporating or cooperating with neuro-stimulating devices, drug pumps, or other therapies. Embodiments of the present invention relate generally to implantable medical devices employing automated cardiac activation sequence monitoring and/or tracking for arrhythmia discrimination. Embodiments of the invention are directed to devices and methods involving sensing a plurality of composite cardiac signals using a plurality of implantable electrodes. A source separation is performed using the sensed plurality of composite cardiac signals and the separation produces one or more cardiac signal vectors associated with one or more cardiac activation sequences that is indicative of ischemia. A change of the one or more cardiac signal vectors is detected using the one or more cardiac signal vectors. Cardiac arrhythmias are discriminated using the one or more cardiac signal vectors.
摘要翻译：心脏监测和/或刺激方法和系统提供监测，诊断，除颤和起搏治疗，或这些功能的组合，包括结合或与神经刺激装置，药物泵或其他疗法组合的心脏系统。本发明的实施方案一般涉及使用自动心脏激活序列监测和/或跟踪用于心律失常鉴别的可植入医疗装置。本发明的实施例涉及使用多个可植入电极感测多个复合心脏信号的装置和方法。使用感测的多个复合心脏信号进行源分离，并且分离产生与指示缺血的一个或多个心脏激活序列相关联的一个或多个心脏信号载体。使用一个或多个心脏信号矢量检测一个或多个心脏信号矢量的改变。使用一个或多个心脏信号载体来区分心律失常。

77. 发明申请

US20060247707A1 Cardiac signal template generation using waveform clustering 有权
公开(公告)号：US20060247707A1
公开(公告)日：2006-11-02
申请号：US11116544
申请日：2005-04-28
申请人： Scott Meyer , Yanting Dong
发明人： Scott Meyer , Yanting Dong
IPC分类号： A61N1/362
CPC分类号： A61B5/04525 , A61N1/371
摘要： Cardiac devices and methods using cardiac waveform clustering for template generation are described. A method of characterizing a cardiac response involves delivering pacing pulses to heart, the pulses having an energy greater than a capture threshold. Cardiac signals are sensed following the pulses. Cardiac signal characteristics, waveforms, and/or features are clustered into a plurality of clusters. A cardiac response template is formed using one or more of the plurality of clusters.

78. 发明申请

US20060116593A1 Cardiac activation sequence monitoring for ischemia detection 有权
标题翻译：心脏激活序列监测缺血检测
公开(公告)号：US20060116593A1
公开(公告)日：2006-06-01
申请号：US11079744
申请日：2005-03-14
申请人： Yi Zhang , Scott Meyer , Jeffrey Stahmann , Carlos Ricci , Marina Brockway , Aaron McCabe , Yinghong Yu , Donald Hopper
发明人： Yi Zhang , Scott Meyer , Jeffrey Stahmann , Carlos Ricci , Marina Brockway , Aaron McCabe , Yinghong Yu , Donald Hopper
IPC分类号： A61B5/04
CPC分类号： A61N1/3702 , A61B5/0452 , A61B5/7203
摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend ischemia using cardiac activation sequence information. Ischemia detection may involve sensing composite cardiac signals using implantable electrodes, and performing a signal separation that produces one or more cardiac activation signal vectors associated with one or more cardiac activation sequences. A change in the signal vector may be detected using subsequent separations. The change may be an elevation or depression of the ST segment of a cardiac cycle or other change indicative of myocardial ischemia, myocardial infarction, or other pathological change. The change may be used to predict, quantify, and/or qualify an event such as an arrhythmia, a myocardial infarction, or other pathologic change. Information associated with the vectors may be stored and used to track the vectors.
摘要翻译：提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。使用心脏信号分离来使用心脏激活序列信息来检测，监测，跟踪和/或趋势性缺血。缺血检测可以涉及使用可植入电极感测复合心脏信号，并且执行产生与一个或多个心脏激活序列相关联的一个或多个心脏激活信号载体的信号分离。可以使用后续分离来检测信号矢量的变化。该变化可以是心脏周期的ST段的升高或抑制或指示心肌缺血，心肌梗死或其他病理变化的其它变化。该变化可用于预测，量化和/或限定诸如心律失常，心肌梗死或其它病理变化的事件。与矢量相关联的信息可以被存储并用于跟踪矢量。

79. 发明申请

US20060095082A1 Cardiac therapy triggered by capture verification 有权
公开(公告)号：US20060095082A1
公开(公告)日：2006-05-04
申请号：US11300674
申请日：2005-12-14
申请人： Haris Sih , Scott Meyer , Paul Haefner
发明人： Haris Sih , Scott Meyer , Paul Haefner
IPC分类号： A61N1/39
CPC分类号： A61N1/3962
摘要： The present invention provides methods and systems for tachyarrhythmia therapy involving pacing the heart to prior to the application of a cardioversion/defibrillation shock. One or more pace pulses are delivered to the arrhythmic chamber or chambers. The pace pulses may be delivered to the heart at an adaptable rate selected to organize the electrical activity of the heart. If the pace pulses produce capture, cardioversion/defibrillation stimulation is delivered.

80. 发明申请

US20050091911A1 Insect suppression station 有权
标题翻译：昆虫抑制站
公开(公告)号：US20050091911A1
公开(公告)日：2005-05-05
申请号：US10697705
申请日：2003-10-29
申请人： Emory Matts , S. Barcay , Scott Meyer , Thomas Nelson , Jeremy Hansen
发明人： Emory Matts , S. Barcay , Scott Meyer , Thomas Nelson , Jeremy Hansen
IPC分类号： A01M1/02 , A01M1/14 , A01M1/20
CPC分类号： A01M1/2011 , A01M1/026 , A01M1/14 , A01M2200/011
摘要： An insect station for luring insects, baiting insects, trapping insects, monitoring insects or any combination of these functions includes a cover that can be moved to provide access to selected insect suppression devices, such as glueboards or baited pads. The insect station may have two changeable pad areas situated facing each other to provide a compact design. In addition, a base portion of the station may have a wall access opening to facilitate applying insecticide behind a wall. The insect station of the present invention may be used with any combination of attractant pads, bait, and glueboards, as well as many other insect suppression devices.
摘要翻译：用于诱捕昆虫，诱饵昆虫，捕获昆虫，监测昆虫或这些功能的任何组合的昆虫站包括可以移动以提供对所选择的昆虫抑制装置（例如胶合板或诱饵垫）的接近的盖子。昆虫站可以具有彼此面对的两个可变的垫区域，以提供紧凑的设计。此外，车站的基座部分可以具有壁通道开口，以便于在墙后面施用杀虫剂。本发明的昆虫站可以与引诱垫，诱饵和胶布的任何组合以及许多其它昆虫抑制装置一起使用。

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