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1. 发明申请

US20070078489A1 Pacing interval adjustment for cardiac pacing response determination 有权
标题翻译：心脏起搏反应确定的起搏间隔调整
公开(公告)号：US20070078489A1
公开(公告)日：2007-04-05
申请号：US11242240
申请日：2005-10-03
申请人： Scott Meyer , Yanting Dong , Kevin Stalsberg , Alok Sathaye
发明人： Scott Meyer , Yanting Dong , Kevin Stalsberg , Alok Sathaye
IPC分类号： A61N1/362
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/7217 , A61N1/3682 , A61N1/3684 , A61N1/3712
摘要： The waveform morphology of a propagated pacing response signal may be adjusted to achieve a waveform morphology that enhances cardiac pacing response determination. One or more pacing intervals may be adjusted to achieve at least one cardiac pacing response waveform morphology that enhances determination of the cardiac pacing response. The heart is paced using the one or more adjusted pacing intervals and the cardiac response to the pacing is determined. The one or more adjusted pacing intervals may include an atrioventricular pacing delay, an interatrial pacing delay, an interventricular pacing delay, or other inter-chamber or inter-site pacing delays. Adjusting the one or more pacing intervals may be used to increase a difference between a first waveform morphology associated with multi-chamber capture and a second waveform morphology associated with single chamber capture.
摘要翻译：可以调节传播的起搏响应信号的波形形态，以实现增强心脏起搏响应确定的波形形态。可以调整一个或多个起搏间隔以实现至少一个心脏起搏响应波形形态，其增强心脏起搏响应的确定。心脏使用一个或多个调整的起搏间隔进行起搏，并且确定对起搏的心脏反应。一个或多个经调整的起搏间隔可以包括房室起搏延迟，房间起搏延迟，室间起搏延迟或其他间室间或间部间起搏延迟。可以使用调整一个或多个起搏间隔来增加与多室捕获相关联的第一波形形态与与单室捕获相关联的第二波形形态之间的差异。

2. 发明申请

US20060293717A1 Methods and systems for selecting capture verification modes 有权
标题翻译：选择捕获验证模式的方法和系统
公开(公告)号：US20060293717A1
公开(公告)日：2006-12-28
申请号：US11168276
申请日：2005-06-28
申请人： Alok Sathaye , Scott Meyer , Derek Bohn
发明人： Alok Sathaye , Scott Meyer , Derek Bohn
IPC分类号： A61N1/00
CPC分类号： A61N1/3712 , A61N1/3627
摘要： Methods and systems are directed to selecting from a variety of capture verification modes. A plurality of capture verification modes, including a beat by beat capture detection mode and a capture threshold testing mode without intervening beat by beat capture detection is provided. An efficacy of at least one of the capture verification modes is evaluated and, based on the evaluation, a capture verification mode is selected.
摘要翻译：方法和系统旨在从各种捕获验证模式中进行选择。提供了多个拍摄验证模式，包括拍拍拍摄检测模式和拍摄阈值测试模式，而不会通过拍摄捕获检测进行中间拍摄。评估捕获验证模式中的至少一个的功效，并且基于评估，选择捕获验证模式。

3. 发明申请

US20070150011A1 Neural stimulation system for reducing atrial proarrhythmia 有权
标题翻译：用于减少心房心律失常的神经刺激系统
公开(公告)号：US20070150011A1
公开(公告)日：2007-06-28
申请号：US11320173
申请日：2005-12-28
申请人： Scott Meyer , Alok Sathaye
发明人： Scott Meyer , Alok Sathaye
IPC分类号： A61N1/36
CPC分类号： A61N1/3702 , A61N1/36114 , A61N1/3624
摘要： A system for reducing proarrhythmic effects of neural stimulation is provided. One aspect of this disclosure relates to an implantable medical device (IMD) for reducing proarrhythmic effects of neural stimulation. The IMD includes a neural stimulator adapted to deliver an electrical signal through at least one electrode to provide vagal stimulation. The IMD also includes a controller adapted to receive atrial arrhythmia vulnerability data and to control a therapeutic stimulator to limit atrial proarrhythmia using the atrial arrhythmia vulnerability data. The controller is further adapted to receive atrial arrhythmic history data and to control a therapeutic stimulator to limit atrial proarrhythmia using the atrial arrhythmic history data, according to various embodiments. According to one embodiment, the therapeutic stimulator includes the neural stimulator. The therapeutic stimulator includes a cardiac stimulator adapted to provide cardiac rhythm management therapy, according to various embodiments. Other aspects and embodiments are provided herein.
摘要翻译：提供了减少神经刺激的心律失常作用的系统。本公开的一个方面涉及用于减少神经刺激的心律失常作用的可植入医疗装置（IMD）。 IMD包括适于通过至少一个电极传递电信号以提供迷走神经刺激的神经刺激器。 IMD还包括一个控制器，适用于接收心房心律失常的脆弱性数据，并使用房性心律失常漏洞数据来控制治疗性刺激器来限制心房心律失常。根据各种实施例，控制器还适于接收心房心律失常历史数据并且使用心房心律不齐历史数据来控制治疗性刺激器来限制心房心律失常。根据一个实施例，治疗刺激器包括神经刺激器。根据各种实施例，治疗性刺激器包括适于提供心律控制治疗的心脏刺激器。本文提供了其它方面和实施例。

4. 发明授权

US08489519B2 Apparatus, systems and methods for online, multi-parcel, multi-carrier, multi-service enterprise parcel shipping management 有权
标题翻译：用于在线，多包裹，多载体，多业务企业包裹运输管理的设备，系统和方法
公开(公告)号：US08489519B2
公开(公告)日：2013-07-16
申请号：US11510801
申请日：2006-08-24
申请人： Daniel F. Williams , David Allison Bennett , Lynn Shaindell Goldhaber , Dennis Glavin , Lory Elizabeth Krett , Charles D. Mentzer , Stephen M. Teglovic , John M. Dietz , William W. Smith, III , Paul Bilibin , Jinyue Liu , Paul R. McLaughlin , Scott Meyer , Sean Hu
发明人： Daniel F. Williams , David Allison Bennett , Lynn Shaindell Goldhaber , Dennis Glavin , Lory Elizabeth Krett , Charles D. Mentzer , Stephen M. Teglovic , John M. Dietz , William W. Smith, III , Paul Bilibin , Jinyue Liu , Paul R. McLaughlin , Scott Meyer , Sean Hu
IPC分类号： G06Q30/00 , G06F17/00 , G06G7/00
CPC分类号： G06Q10/0835 , G06Q10/08 , G06Q10/083 , G06Q10/0834 , G06Q10/08345 , G06Q10/10 , G06Q10/101 , G06Q30/0282 , G06Q30/0601
摘要： The present invention provides a plurality of Enterprises with a single online user interface with which the Enterprise can provide Enterprise Shippers, shipping origination users and shipping intermediary users with an automated parcel management system for a plurality of supported Carriers for a plurality of services. The present invention provides for the hierarchical definition of users, including the establishment of at least one user for each Enterprise as a Super-Administrator with the highest level of privileges and authority for the Enterprise, and the identification of other users as Sub-Administrators, Desktop Users and Shipping Station Users. The present invention also provides for the hierarchical definition of organizational units within each Enterprise, including the definition of sites, groups within a site, and users within a group and for a distinct definition of policies, privileges, and other types of specifications for each user level, each user, and each organizational unit.
摘要翻译：本发明提供了具有单个在线用户界面的多个企业，企业可以通过该企业提供企业托运人，为起始用户和运输中间用户提供用于多个服务的多个被支持运营商的自动包裹管理系统。本发明提供了用户的分层定义，包括为每个企业建立至少一个具有企业级别的权限和权限的超级管理员的用户，以及将其他用户识别为子管理员，桌面用户和航运站用户。本发明还提供了每个企业内的组织单位的分层定义，包括站点的定义，站点内的组以及组内的用户以及针对每个用户的策略，特权和其他类型的规范的明确定义级别，每个用户和每个组织单位。

5. 发明授权

US08321002B2 Arrhythmia discrimination using ECG's sensed from multiple implanted electrodes 有权
标题翻译：使用从多个植入电极感测的心电图进行心律失常辨别
公开(公告)号：US08321002B2
公开(公告)日：2012-11-27
申请号：US13027608
申请日：2011-02-15
申请人： Yi Zhang , Carlos A. Ricci , Jeffrey E. Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
发明人： Yi Zhang , Carlos A. Ricci , Jeffrey E. Stahmann , Aaron McCabe , Scott Meyer , Yinghong Yu
IPC分类号： A61B5/0464
CPC分类号： A61B5/04011 , A61B5/7203
摘要： Cardiac monitoring and/or stimulation methods and systems provide for monitoring, diagnosing, defibrillation and pacing therapies, or a combination of these capabilities, including cardiac systems incorporating or cooperating with neuro-stimulating devices, drug pumps, or other therapies. Embodiments of the present invention relate generally to implantable medical devices employing automated cardiac activation sequence monitoring and/or tracking for arrhythmia discrimination. Embodiments of the invention are directed to devices and methods involving sensing a plurality of composite cardiac signals using a plurality of implantable electrodes. A source separation is performed using the sensed plurality of composite cardiac signals and the separation produces one or more cardiac signal vectors associated with one or more cardiac activation sequences that is indicative of ischemia. A change of the one or more cardiac signal vectors is detected using the one or more cardiac signal vectors. Cardiac arrhythmias are discriminated using the one or more cardiac signal vectors.
摘要翻译：心脏监测和/或刺激方法和系统提供监测，诊断，除颤和起搏治疗，或这些能力的组合，包括结合或与神经刺激装置，药物泵或其他疗法组合的心脏系统。本发明的实施方案一般涉及使用自动心脏激活序列监测和/或跟踪用于心律失常鉴别的可植入医疗装置。本发明的实施例涉及使用多个可植入电极感测多个复合心脏信号的装置和方法。使用感测的多个复合心脏信号进行源分离，并且分离产生与指示缺血的一个或多个心脏激活序列相关联的一个或多个心脏信号载体。使用一个或多个心脏信号矢量检测一个或多个心脏信号矢量的改变。使用一个或多个心脏信号载体来区分心律失常。

6. 发明授权

US08145296B2 Adaptive windowing for cardiac waveform discrimination 有权
标题翻译：心脏波形鉴别的自适应窗口
公开(公告)号：US08145296B2
公开(公告)日：2012-03-27
申请号：US12538297
申请日：2009-08-10
申请人： Kevin J. Stalsberg , Yanting Dong , Scott Meyer , Eric K. Enrooth , Derek D. Bohn
发明人： Kevin J. Stalsberg , Yanting Dong , Scott Meyer , Eric K. Enrooth , Derek D. Bohn
IPC分类号： A61B5/042
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/0472 , A61B5/7217
摘要： Cardiac devices and methods provide adaptation of detection windows used to determine a cardiac response to pacing. Adapting a detection window involves sensing a cardiac signal indicative of a particular type of cardiac pacing response, and detecting a feature of the sensed cardiac signal. The cardiac response detection window associated with the type of cardiac pacing response is preferentially adjusted based on the location of the detected cardiac feature. Preferential adjustment of the detection window may involve determining a direction of change between the detection window and the detected feature. The detection window may be adapted more aggressively in a more preferred direction and less aggressively in a less preferred direction.
摘要翻译：心脏装置和方法提供用于确定对起搏的心脏反应的检测窗口的适应。适应检测窗口包括感测指示特定类型的心脏起搏反应的心脏信号，以及检测感测到的心脏信号的特征。基于检测到的心脏特征的位置优先调整与心脏起搏响应类型相关联的心脏响应检测窗口。检测窗口的优先调整可以包括确定检测窗口和检测到的特征之间的变化方向。检测窗口可以在更优选的方向上更积极地改变，并且在较不优选的方向上较不积极地适配。

7. 发明申请

US20080166208A1 WET CLEAN SYSTEM DESIGN 失效
标题翻译：湿清洁系统设计
公开(公告)号：US20080166208A1
公开(公告)日：2008-07-10
申请号：US11620610
申请日：2007-01-05
申请人： Paul Lester , Scott Meyer , Wyland L. Atkins , Douglas Richards , Constantin Predoaica , Jeffrey Hudgens , Charles Carlson , Penchala Kankanala , Mike Rice , James S. Papanu , Evanson G. Baiya , John J. Rosato
发明人： Paul Lester , Scott Meyer , Wyland L. Atkins , Douglas Richards , Constantin Predoaica , Jeffrey Hudgens , Charles Carlson , Penchala Kankanala , Mike Rice , James S. Papanu , Evanson G. Baiya , John J. Rosato
IPC分类号： H01L21/67
CPC分类号： H01L21/67766 , H01L21/67051 , H01L21/68707 , Y10S134/902
摘要： The present invention generally provides an apparatus and method for processing and transferring substrates in a multi-chamber processing system that has the capability of receiving and performing single substrate processing steps performed in parallel, while using the many favorable aspects of batch processing. Embodiments of the invention described herein are adapted to maximize system throughput, reduce system cost, reduce cost per substrate during processing, increase system reliability, improve the device yield on the processed substrates, and reduce system footprint. In one embodiment, the cluster tool is adapted to perform a wet/clean process sequence in which various substrate cleaning processes are performed on a substrate in the cluster tool.
摘要翻译：本发明通常提供了一种在多室处理系统中处理和传送基板的装置和方法，该多室处理系统具有在使用批处理的许多有利方面的同时并行执行的单个基板处理步骤的能力。本文描述的本发明的实施例适用于最大化系统吞吐量，降低系统成本，在处理期间降低每个基板的成本，增加系统可靠性，提高处理的基板上的装置产量，并减少系统占用面积。在一个实施例中，群集工具适于执行湿/清洁处理序列，其中在群集工具中的基板上执行各种基板清洁处理。

8. 发明申请

US20080055543A1 Image adjustment derived from optical imaging measurement data 有权
标题翻译：从光学成像测量数据导出的图像调整
公开(公告)号：US20080055543A1
公开(公告)日：2008-03-06
申请号：US11511651
申请日：2006-08-29
申请人： Scott Meyer , Xunchang Chen , Rodney P. Chin
发明人： Scott Meyer , Xunchang Chen , Rodney P. Chin
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/113
摘要： A method and apparatus for imaging within the eye is provided whereby a component of eye position is detected using optical imaging data. Tracking eye position over time and correctly registering imaging data for scan locations or using eye position to detect decentration achieves improved imaging. In one embodiment, essentially perpendicular B-scans are imaged sequentially and the corneal arc within each B-scan is analyzed to determine the vertex of the eye. The eye vertex is tracked over pairs of perpendicular B-scans to determine eye motion. In another embodiment, the decentration in the Pachymetry map is removed by correcting for the misalignment of the center of the Pachymetry map and the actual location of the corneal vertex.
摘要翻译：提供一种用于眼内成像的方法和装置，由此使用光学成像数据检测眼睛位置的分量。随着时间的推移跟踪眼睛位置并正确记录扫描位置的成像数据或使用眼睛位置来检测偏心，实现了改善的成像。在一个实施例中，基本上垂直的B扫描被顺序成像，并且分析每个B扫描内的角膜弧以确定眼睛的顶点。通过成对的垂直B扫描来跟踪眼睛顶点以确定眼睛运动。在另一个实施例中，通过校正Pachymetry图的中心和角膜顶点的实际位置的偏移来去除Pachymetry图中的偏心。

9. 发明申请

US20070021793A1 Pacing output determination based on selected capture threshold values 有权
标题翻译：基于所选捕获阈值的起搏输出确定
公开(公告)号：US20070021793A1
公开(公告)日：2007-01-25
申请号：US11185573
申请日：2005-07-19
申请人： John Voegele , Clayton Foster , David Yost , Scott Meyer , Yanting Dong , Kevin Stalsberg , Derek Bohn , Eric Enrooth
发明人： John Voegele , Clayton Foster , David Yost , Scott Meyer , Yanting Dong , Kevin Stalsberg , Derek Bohn , Eric Enrooth
IPC分类号： A61N1/362
CPC分类号： A61N1/3712
摘要： Approaches for adjusting the pacing energy delivered by a pacemaker are provided. Adjusting the pacing energy involves performing a plurality of capture threshold tests, each capture threshold test measuring a capture threshold of the heart. One or more measured captured thresholds are selected, including at least one capture threshold that is higher relative to other measured capture thresholds acquired by the plurality of capture threshold tests. The pacing energy is adjusted based on the one or more selected capture thresholds.
摘要翻译：提供了调节由起搏器提供的起搏能量的方法。调整起搏能量包括执行多个捕获阈值测试，每个捕获阈值测试测量心脏的捕获阈值。选择一个或多个测量的捕获阈值，包括相对于通过多个捕获阈值测试获取的其他测量的捕获阈值更高的捕获阈值。基于一个或多个选择的捕获阈值来调整起搏能量。

10. 发明申请

US20060287685A1 Multi-chamber cardiac capture detection using cross chamber sensing 有权
公开(公告)号：US20060287685A1
公开(公告)日：2006-12-21
申请号：US11157426
申请日：2005-06-21
申请人： Scott Meyer , David Yonce , David Ternes
发明人： Scott Meyer , David Yonce , David Ternes
IPC分类号： A61N1/362
CPC分类号： A61N1/368 , A61N1/3684 , A61N1/3712
摘要： Methods and systems involve multi-chamber cardiac capture detection utilizing sensing during a cross-chamber refractory period. First and second pacing pulses are delivered to first and second heart chamber. Capture or non-capture of the second heart chamber is determined. Sensing in the first heart chamber is performed to sense for cross-chamber propagation initiated by the second pacing pulse. Capture of the first chamber is detected if capture of the second heart chamber is detected and if the cross-chamber propagation is not detected.

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