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71. 发明申请

WO2011072221A1 SYSTEMS AND METHODS FOR DETERMINING THE LIKELIHOOD OF ENDOCARDIAL BAROTRAUMA IN TISSUE DURING ABLATION 审中-公开
标题翻译：系统和方法，用于确定组织中骨髓间充质干细胞
公开(公告)号：WO2011072221A1
公开(公告)日：2011-06-16
申请号：PCT/US2010/059884
申请日：2010-12-10
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , FISH, Jeffrey , BYRD, Israel , CLARK, Lynn , DANDO, Jeremy , GEURKINK, Christopher , LATHIA, Rohan , PURYEAR, Harry , AFONSO, Valtino , PAUL, Saurav
发明人： FISH, Jeffrey , BYRD, Israel , CLARK, Lynn , DANDO, Jeremy , GEURKINK, Christopher , LATHIA, Rohan , PURYEAR, Harry , AFONSO, Valtino , PAUL, Saurav
IPC分类号： A61B18/04
CPC分类号： A61B18/1492 , A61B5/036 , A61B5/0538 , A61B2017/00026 , A61B2017/00119 , A61B2018/00351 , A61B2018/00702 , A61B2018/00875 , A61B2034/105 , A61B2034/2051 , A61B2034/2053 , A61B2034/301 , A61B2090/372
摘要： A method and system (10) for determining a likelihood of barotrauma occurring in tissue during the formation of a lesion therein is provided. The system (10) includes an electronic control unit (ECU) (34). The ECU (34) is configured to acquire at least one value of at least one component of a complex impedance between an electrode (16) and the tissue (12). The ECU (34) is further configured to calculate an index responsive to the at least one value of the at least one complex impedance component. The index is indicative of a likelihood of barotrauma occurring in the tissue (12).
摘要翻译：提供了一种用于在其中形成病变期间确定在组织中发生的气压伤的可能性的方法和系统（10）。系统（10）包括电子控制单元（ECU）（34）。 ECU（34）被配置为获取电极（16）和组织（12）之间的复阻抗的至少一个分量的至少一个值。 ECU（34）还被配置为响应于至少一个复阻抗分量的至少一个值来计算索引。该指数表示在组织（12）中发生气压伤的可能性。

72. 发明申请

WO2010078196A1 FAST-ACTING OR ROTATING TRANSSEPTAL NEEDLE 审中-公开
标题翻译：快速或旋转传递针
公开(公告)号：WO2010078196A1
公开(公告)日：2010-07-08
申请号：PCT/US2009/069433
申请日：2009-12-23
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , PAUL, Saurav , STANGENES, Todd, Raymond , HEIMBECHER, Reed, R.
发明人： PAUL, Saurav , STANGENES, Todd, Raymond , HEIMBECHER, Reed, R.
IPC分类号： A61B17/00
CPC分类号： A61B17/3403 , A61B17/3478 , A61B17/3498 , A61B2017/00243 , A61B2017/3405 , A61M29/00
摘要： A transseptal medical device (10, 110) is provided including a dilator (12, 112), a needle (14, 114), and a needle control mechanism (22, 122). The needle (14, 114) may be disposed within the dilator (12, 112), and the needle control mechanism (22, 122) may be operably connected to a proximal end (24, 124, 16, 116) of the needle (14, 114) or the dilator (12, 112) for selective adjustment of the distal end (26, 126) of the needle (14, 114) from a first position within the dilator (12, 112) to a second position external to the dilator (12, 112). The needle control mechanism (22) may include an actuator (32) configured for rotation within the dilator in one embodiment.
摘要翻译：提供了一种经血管医疗装置（10,110），其包括扩张器（12,112），针（14,114）和针控制机构（22,122）。针（14,114）可以设置在扩张器（12,112）内，并且针控制机构（22,122）可以可操作地连接到针的近端（24,124,16,116） 14,114）或扩张器（12,112），用于选择性地将针（14,114）的远端（26,126）从扩张器（12,112）内的第一位置调节到第二位置扩张器（12,112）。针控制机构（22）可以包括在一个实施例中构造成用于在扩张器内旋转的致动器（32）。

73. 发明申请

WO2009120940A2 ROBOTIC CATHETER SYSTEM 审中-公开
标题翻译：机器人导管系统
公开(公告)号：WO2009120940A2
公开(公告)日：2009-10-01
申请号：PCT/US2009/038525
申请日：2009-03-27
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , KIRSCHENMAN, Mark , HAUCK, John
发明人： KIRSCHENMAN, Mark , HAUCK, John
IPC分类号： A61B19/00
CPC分类号： A61B34/30 , A61B18/1492 , A61B34/20 , A61B34/37 , A61B34/71 , A61B34/76 , A61B34/77 , A61B90/06 , A61B2017/00026 , A61B2017/00477 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2034/2055 , A61B2034/301 , A61B2034/305 , A61B2034/741 , A61B2034/742 , A61B2090/064 , A61M25/0113 , A61M25/0147
摘要： A robotic catheter system (10) including one or more robotic catheter manipulator assemblies (300) supported on a manipulator support structure (500). The robotic catheter manipulator assembly may include one or more removably mounted robotic catheter device cartridges (400) and robotic sheath device cartridges, with each cartridge being generally linearly movable relative to the robotic catheter manipulator assembly. An input control system (100) may be provided for controlling operation of the robotic catheter manipulator assembly. A visualization system (12) may include one or more display monitors for displaying a position of a catheter and/or a sheath respectively attached to the robotic catheter and sheath device cartridges.
摘要翻译：机器人导管系统（10），其包括支撑在操纵器支撑结构（500）上的一个或多个机器人导管操纵器组件（300）。机器人导管操纵器组件可以包括一个或多个可移除地安装的机器人导管装置盒（400）和机器人护套装置盒，每个盒通常相对于机器人导管操纵器组件可线性移动。可以提供输入控制系统（100）以控制机器人导管操纵器组件的操作。可视化系统（12）可以包括一个或多个显示监视器，用于显示分别附接到机器人导管和鞘装置盒的导管和/或护套的位置。

74. 发明申请

WO2009085652A1 DEFLECTABLE CATHETER CONSTRUCTED TO INHIBIT COMPONENT MIGRATION 审中-公开
标题翻译：构成禁止组件移动的防盗导管
公开(公告)号：WO2009085652A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/086561
申请日：2008-12-12
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HASTINGS, John M. , LATRAILLE, Gary B. , YOUNGER, Eliazbeth
发明人： HASTINGS, John M. , LATRAILLE, Gary B. , YOUNGER, Eliazbeth
IPC分类号： A61M25/04
CPC分类号： A61M25/0147 , A61B18/1492 , A61B2017/00526 , A61B2018/00839 , A61M25/0009 , A61M25/0069 , A61M25/0082 , A61M25/0144 , Y10T29/4913 , Y10T29/49169 , Y10T29/49174 , Y10T29/49185 , Y10T29/49194
摘要： A method of manufacturing a deflectable electrophysiological catheter (10) includes constructing a shaft (14) having a distal end (16) and at least one lumen (18). The method further includes inserting a component (34) into the lumen, and processing at least a portion of the distal end to reduce the cross-sectional profile of the lumen to capture/confine the component. The catheter includes a shaft (14) having at least one lumen (18). The lumen includes longitudinally-extending trough (24) having a longitudinally-extending recess (28) for receiving a component (34), and a longitudinally extending open edge (30). A longitudinally-extending channel (26) defined by a longitudinally-extending cavity (32) and open edge of the trough (24). A planarity wire or member (44) disposed within the cavity (32) closes the open edge of the trough (24) to within a pre-defined tolerance less than the size of the component and retains the component therein.
摘要翻译：制造可偏转电生理导管（10）的方法包括构造具有远端（16）和至少一个内腔（18）的轴（14）。该方法还包括将部件（34）插入内腔中，并且处理远端的至少一部分以减小管腔的横截面轮廓以捕获/限制部件。导管包括具有至少一个内腔（18）的轴（14）。管腔包括纵向延伸的槽（24），其具有用于容纳部件（34）的纵向延伸的凹部（28）和纵向延伸的开口边缘（30）。由纵向延伸的空腔（32）和槽（24）的开口边缘限定的纵向延伸通道（26）。设置在空腔（32）内的平面线或构件（44）将槽（24）的开口边缘封闭在小于部件尺寸的预定公差内，并将部件保持在其中。

75. 发明申请

WO2009085458A1 SYSTEM AND METHOD FOR MEASUREMENT OF AN IMPEDANCE USING A CATHETER SUCH AS AN ABLATION CATHETER 审中-公开
标题翻译：使用导管等测量阻抗的系统和方法
公开(公告)号：WO2009085458A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/084200
申请日：2008-11-20
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , MILLER, Stephan P. , KASTNER, Glen H. , DENO, D. Curtis
发明人： MILLER, Stephan P. , KASTNER, Glen H. , DENO, D. Curtis
IPC分类号： A61B18/14
CPC分类号： A61B18/1206 , A61B18/1492 , A61B2018/00577 , A61B2018/00875
摘要： A catheter and patch electrode system (10) for use with an apparatus (e.g., an ablation generator) having a 4-wire interface (62) for improved impedance measurements which includes two source connectors for receiving excitation signals and a pair of sense connector wires for measuring impedances. A radiofrequency ablation generator (16) can produce a signal between a source wire and an indifferent return patch electrode (37). A source lead (46) is electrically coupled to a tip electrode (28T) and extends through to a proximal end (and an optional sense lead can couple the tip electrode as well). A source return (56) and a sense return (56) (e.g., skin patch(es)) can be combined with the indifferent return (37) for improved performance when placed on opposite sides of a patient. The excitation signal traverses the complex (tissue) load returning to the generator (16) via patch electrode and impedance is measured by observing the voltage drop across the sense connectors.
摘要翻译：一种用于与具有用于改善阻抗测量的4线接口（62）的装置（例如，消融发生器）一起使用的导管和贴片电极系统（10），其包括用于接收激励信号的两个源连接器和一对感测连接器线用于测量阻抗。射频消融发生器（16）可以在源极线和无关的返回贴片电极（37）之间产生信号。源极（46）电耦合到尖端电极（28T）并且延伸到近端（并且可选的感测引线也可以连接尖端电极）。可以将源返回（56）和感测返回（56）（例如，皮肤贴片）与无关的返回（37）组合，以在放置在患者的相对侧时改善性能。激励信号通过贴片电极穿过返回发生器（16）的复合（组织）负载，并通过观察感测连接器两端的电压降来测量阻抗。

76. 发明申请

WO2009082740A1 FINGER-MOUNTED OR ROBOT-MOUNTED TRANSDUCER DEVICES AND RELATED METHODS OF USE AND MANUFACTURE 审中-公开
标题翻译：手指安装或机器人安装的传感器装置及相关使用和制造方法
公开(公告)号：WO2009082740A1
公开(公告)日：2009-07-02
申请号：PCT/US2008/088034
申请日：2008-12-22
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John, W.
发明人： SLIWA, John, W.
IPC分类号： A61B18/04
CPC分类号： A61N7/02 , A61B8/4227 , A61B8/4272 , A61B34/30 , A61B34/71 , A61B90/53 , A61B2018/00023
摘要： A transducer device (10) includes mounting body (12) coupling device (10) to an operator's digit or to a deployable member of a robotic surgical system for mounting and manipulating the device. The device includes a transducer housing (14) coupled to mounting body (12) having a receiving portion and includes therapy delivery transducer (16) and a fluid irrigation lumen (18) coupled to the receiving portion and connected to an energy supply to transmit energy from an emitting surface (20) toward target tissue (TT). The device can include gas reservoir (28) configured to decrease energy transfer thereacross. The device can include a membrane (30) coupled located adjacent the emitting surface and a lumen (18) for providing fluid or gel to membrane (30). The device can include imaging capability (16'), diverse sensors (13,13') to assess tissue and therapy delivery results therefrom and also spatial tracking elements (for magnetic, electrical field, and fluoroscopic location/orientation).
摘要翻译：换能器装置（10）包括将装置（10）连接到操作人员的数字上或者用于安装和操纵装置的机器人手术系统的可展开构件的安装体（12）。该装置包括耦合到具有接收部分的安装体（12）的换能器壳体（14），并且包括联接到接收部分并连接到能量传递能量的治疗输送换能器（16）和流体冲洗内腔（18）从发射表面（20）朝向靶组织（TT）。该装置可以包括被配置为减少其上的能量传递的气体储存器（28）。该装置可以包括耦合定位在发射表面附近的膜（30）和用于向膜（30）提供流体或凝胶的内腔（18）。该装置可以包括成像能力（16'），各种传感器（13,13'），用于评估组织和治疗传递结果，以及空间跟踪元件（用于磁场，电场和荧光检查位置/取向）。

77. 发明申请

WO2009082570A1 MEDICAL CATHETER ASSEMBLY WITH DEFLECTION PULL RING AND DISTAL TIP INTERLOCK 审中-公开
标题翻译：医疗导管组件与偏转拉环和远程提前互锁
公开(公告)号：WO2009082570A1
公开(公告)日：2009-07-02
申请号：PCT/US2008/083731
申请日：2008-11-17
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , POTTER, Daniel, J.
发明人： POTTER, Daniel, J.
IPC分类号： A61M25/092
CPC分类号： A61M25/0147 , A61B18/1492 , A61B2017/003 , A61B2018/1472 , A61M2025/015
摘要： A medical catheter assembly (12) includes a deflectable catheter shaft (21), a distal tip with tip element and a mounting shaft (38), and a pull ring assembly (50), the distal tip (30) defining guide channels (41, 42) for pull wires (52, 53) of the pull ring assembly (50) such that the wires initially extend from the pull ring (51) toward the tip element and then loop back and through the catheter shaft (21) to handle actuator (120). Pulling the wires tilts the pull ring and deflects the catheter shaft with the pull ring moving toward the tip element and interlocking therewith. Stress forces on the connection joints between the pull wires and the pull ring are dissipated, reducing the incidence of failure of the pull ring assembly. The catheter can be non-irrigated ablation catheter with a tip electrode, or an irrigated ablation catheter further including a fluid manifold (33).
摘要翻译：医疗导管组件（12）包括可偏转的导管轴（21），具有尖端元件的远端和安装轴（38）以及拉环组件（50），所述远侧末端（30）限定引导通道（41），42），用于所述拉环组件（50）的拉线（52,53），使得所述电线最初从所述拉环（51）朝向所述尖端元件延伸，然后环绕并穿过所述导管轴（21）以处理致动器（120）。拉动导线使拉环倾斜并使导管轴偏转，拉环朝向尖端元件移动并与其互锁。拉线和拉环之间的连接接头上的应力消耗，从而减少拉环组件的故障发生率。导管可以是具有尖端电极的非灌注消融导管，或者还包括流体歧管（33）的灌洗消融导管。

78. 发明申请

WO2009079158A1 SYSTEM FOR DISPLAYING DATA RELATING TO ENERGY EMITTING TREATMENT DEVICES TOGETHER WITH ELECTROPHYSIOLOGICAL MAPPING DATA 审中-公开
标题翻译：用于显示与电生理图像数据相关的能量发射处理设备的数据系统
公开(公告)号：WO2009079158A1
公开(公告)日：2009-06-25
申请号：PCT/US2008/084302
申请日：2008-11-21
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , SLIWA, John W.
发明人： SLIWA, John W.
IPC分类号： A61B5/02
CPC分类号： A61B5/042 , A61B5/044 , A61B34/20 , A61B34/25 , A61N7/02
摘要： A system and method for treatment of tissue is provided. An electronic control unit (22) is configured to generate displays signals used to create a graphical user interface. The display signals are generated in response to a first set of position signals indicative of the position of an electrophysiology mapping electrode relative to the tissue (12) and a second set of position signals indicative of the position of a treatment device (20), such as a high intensity focused ultrasound transducer, that is configured to generate a beam of energy towards a selected region in the tissue (12). The graphical user interface displays an electrophysiology map of the tissue and an image of at least one of the treatment device and a beam of energy which may be superimposed on the electrophysiology map.
摘要翻译：提供了一种用于治疗组织的系统和方法。电子控制单元（22）被配置为产生用于创建图形用户界面的显示信号。响应于指示电生理学映射电极相对于组织（12）的位置的第一组位置信号和指示治疗装置（20）的位置的第二组位置信号而产生显示信号，例如作为高强度聚焦超声换能器，其被配置为朝向组织（12）中的选定区域产生能量束。图形用户界面显示组织的电生理学图，以及可以叠加在电生理学图上的治疗装置和能量束中的至少一个的图像。

79. 发明申请

WO2009079138A1 CARDIAC ABLATION CATHETER WITH OXYGEN SATURATION SENSOR 审中-公开
标题翻译：带氧气饱和传感器的心脏吸引导管
公开(公告)号：WO2009079138A1
公开(公告)日：2009-06-25
申请号：PCT/US2008/083726
申请日：2008-11-17
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , WANG, Huisun
发明人： WANG, Huisun
IPC分类号： A61M29/00
CPC分类号： A61B5/14542 , A61B5/1459 , A61B18/1492 , A61B2017/003 , A61B2018/00351
摘要： Positioning of the distal end of a catheter at a desired location in an atrium of a patient's heart, can be determined or verified through measurement of blood gas values proximate the end. In one embodiment, an oximeter is used to monitor oxygen saturation to distinguish between de-oxygenated venous blood and well-oxygenated arterial blood. Optical signals may be transmitted to the distal end of the catheter and received therefrom via optical fibers. Specifically, a catheter (300) has a number of optical fiber ends (308,310,312) disposed at a distal end (304) thereof. A first fiber end (310) transmits the red and infrared optical signals. Fiber ends (308, 312) are used for detecting reflected optical signals which are then processed by a detector and oximeter instrument to provide oxygen saturation readings that indicating the position of the distal end of the catheter or successful penetration of the interatrial septum.
摘要翻译：可以通过测量靠近末端的血气值来确定或验证导管远端在患者心脏的心房中的期望位置的位置。在一个实施例中，使用血氧计来监测氧饱和度以区分脱氧的静脉血和充分充氧的动脉血。光信号可以被传输到导管的远端并经由光纤从其中接收。具体地，导管（300）具有设置在其远端（304）处的多个光纤端（308,310,312）。第一光纤端（310）传输红光和红外光信号。光纤端（308,312）用于检测反射的光信号，然后由检测器和血氧计仪器进行处理，以提供指示导管远端的位置或成功穿透房间隔的氧饱和度读数。

80. 发明申请

WO2009067695A1 METHODS AND SYSTEM FOR OCCLUDING VESSELS DURING CARDIAC ABLATION 审中-公开
标题翻译：心脏消融期间血管损伤的方法和系统
公开(公告)号：WO2009067695A1
公开(公告)日：2009-05-28
申请号：PCT/US2008/084406
申请日：2008-11-21
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , KAUPHUSMAN, James V. , D'AVILA, Andre , REDDY, Vivek Y.
发明人： KAUPHUSMAN, James V. , D'AVILA, Andre , REDDY, Vivek Y.
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B5/0422 , A61B18/18 , A61B18/20 , A61B2017/22067 , A61B2018/00577 , A61B2018/00797 , A61B2018/00821 , A61B2018/025
摘要： A method is provided for ablating a portion of the myocardium. The method includes inserting an occlusion catheter into a vessel on a heart, occluding the vessel using the occlusion catheter, inserting an ablation catheter into a chamber of the heart, positioning the ablation catheter against the myocardium, and ablating a portion of the myocardium while the vessel is occluded. The system includes an occlusion catheter having a catheter body including a tubular member having a distal portion and a bend located in the distal portion, a balloon located proximal of the bend and configured to contact an inner surface of the coronary sinus when positioned therewithin, a plurality of marker bands positioned on the catheter body, and a plurality of electrodes positioned on the catheter body.
摘要翻译：提供了一种用于烧蚀心肌的一部分的方法。该方法包括将闭塞导管插入心脏上的容器中，使用闭塞导管封闭血管，将消融导管插入心脏的腔室中，将消融导管定位在心肌上，以及消融心肌的一部分，同时血管闭塞所述系统包括具有导管主体的阻塞导管，所述导管主体包括管状构件，所述管状构件具有位于所述远侧部分中的远侧部分和弯曲部，位于所述弯曲部的近侧的球囊，并且构造成在定位于其中时与所述冠状窦的内表面接触; 定位在导管主体上的多个标记带以及位于导管主体上的多个电极。

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