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71. 发明专利

JP2003240785A METHOD AND APPARATUS FOR DECISION OF REMOVAL OF HELICOBACTER PYLORI 审中-公开
公开(公告)号：JP2003240785A
公开(公告)日：2003-08-27
申请号：JP2002043052
申请日：2002-02-20
申请人： ABBOTT JAPAN CO LTD
发明人： INOUE YUZO
IPC分类号： G01N33/569 , G01N33/573
摘要： PROBLEM TO BE SOLVED: To more precisely and simply decide whether Hp is removed or not by using a PG1 value and a PG2 value in humor such as blood or the like. SOLUTION: A PG (pepinogen) 1/PG2 ratio obtained on the basis of the PG1 value and the PG2 value and the rate of change of the PG1/PG2 ratio before and after its separation are used, they are introduced to a probability density function, and the removal of the Hp can be decided precisely and simply. COPYRIGHT: (C)2003,JPO

72. 发明专利

JP2014074696A Specimen automatic conveyance system for performing calibration or control measurement of analyzer, and method of the same 审中-公开
标题翻译：用于执行分析仪的校准或控制测量的样品自动输送系统及其方法
公开(公告)号：JP2014074696A
公开(公告)日：2014-04-24
申请号：JP2012223300
申请日：2012-10-05
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： KANEHIRO MASAHIKO , MORI MASAYUKI
IPC分类号： G01N35/00 , G01N35/04
摘要： PROBLEM TO BE SOLVED: To provide a specimen automatic conveyance system capable of efficiently performing calibration or control measurement.SOLUTION: The specimen automatic conveyance system reads information of a specimen existing on a conveyance lane 250 thereof, identifies, from the read information, a calibrator or a control specimen for at least one analyzer 210, transfers the identified calibrator or control specimen to the at least one analyzer, samples the transferred specimen, and performs calibration or control measurement of the at least one analyzer.
摘要翻译：要解决的问题：提供能够有效地执行校准或控制测量的样本自动传送系统。解决方案：样本自动传送系统读取存在于其传送通道250上的样本的信息，从读取的信息中识别校准器或用于至少一个分析器210的控制样本，将所识别的校准器或控制样本传送到所述至少一个分析器，对所转移的样本进行采样，并对所述至少一个分析器进行校准或控制测量。

73. 发明专利

JP2007170992A Method for immunological measurement of homocysteines 审中-公开
标题翻译：免疫学测定方法
公开(公告)号：JP2007170992A
公开(公告)日：2007-07-05
申请号：JP2005369198
申请日：2005-12-22
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： YOSHIMURA TORU
IPC分类号： G01N33/53 , G01N33/531
CPC分类号： G01N33/6815
摘要： PROBLEM TO BE SOLVED: To provide a method for immunological measurement of homocysteines, and capable of readily and efficiently excluding the effects of immunoreaction inhibitors derived from biological samples, since it is known that measurement values vary due to the effects of immunoreaction inhibitors that have been derived from biological samples, and to provide a kit used for the same.
SOLUTION: The exclude effects of immunoreaction inhibitors can be excluded by making homocysteine react with an antibody in the presence of polyanions. A specimen and the antibody are made to react in the presence of exogenous polyanions, to immunologically measure the homocysteine contained in a biological sample according to the method.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于免疫测量同型半胱氨酸的方法，并且能够容易且有效地排除衍生自生物样品的免疫反应抑制剂的作用，因为已知测量值由于免疫反应抑制剂的作用而变化其衍生自生物样品，并提供用于其的试剂盒。解决方案：通过在聚阴离子存在下使同型半胱氨酸与抗体反应，排除免疫反应抑制剂的排除效果。使样品和抗体在外源聚阴离子存在下反应，根据该方法免疫测量生物样品中所含的同型半胱氨酸。版权所有（C）2007，JPO＆INPIT

74. 发明专利

JP2005090992A Stabilization solidification anti-scc antibody reagent 审中-公开
标题翻译：稳定化抗SCC抗体试剂
公开(公告)号：JP2005090992A
公开(公告)日：2005-04-07
申请号：JP2003321045
申请日：2003-09-12
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： CHIBA RIYOUTAROU , KINUKAWA HIDEKI , KUMAGAI YASUYUKI
IPC分类号： G01N33/543 , G01N33/574
摘要： PROBLEM TO BE SOLVED: To stably preserve a solidification anti-SCC antibody which is a measuring reagent for a squamous cell carcinoma-related antigen (SCC antigen) which is a useful tumor marker, and to remove restriction of its utilization.
SOLUTION: The solidification anti-SCC antibody is preserved in acidic solution. Hereby, the heat stability thereof can be improved, and also a prescribed measurement result can be acquired in a reaction with the SCC antigen. Consequently, this stabilization solidification anti-SCC antibody reagent and an immunoassay method using it can be provided, and the clinical significance of the SCC antigen can be grasped precisely with higher reliability.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：为了稳定地保持作为有用的肿瘤标记物的鳞状细胞癌相关抗原（SCC抗原）的测定试剂的凝固抗SCC抗体，并且消除其利用的限制。解决方案：将固化的抗SCC抗体保存在酸性溶液中。由此，可以提高其热稳定性，并且可以在与SCC抗原的反应中获得规定的测定结果。因此，可以提供这种稳定化固化抗SCC抗体试剂和使用它的免疫测定方法，可以更高的可靠性精确地掌握SCC抗原的临床意义。版权所有（C）2005，JPO＆NCIPI

75. 发明专利

JP2004313269A Protective cover for medical instrument 审中-公开
公开(公告)号：JP2004313269A
公开(公告)日：2004-11-11
申请号：JP2003108227
申请日：2003-04-11
申请人： Abbott Japan Co Ltd , アボットジャパン株式会社
发明人： SAITO RYOJI
IPC分类号： A61B5/145
摘要： PROBLEM TO BE SOLVED: To provide a protective cover for a medical instrument which prevents the reduction of a measurement accuracy resulted from carelessness when a patient handles the medical instrument, and at the same time, reduces a psychological burden of the patient who uses the medical instrument.
SOLUTION: This protective cover 30 has a plate section 32 which can substantially cover the surface of the medical instrument, and side sections 34a to 34c which are integrally provided on the outer edge in a manner to surround the plate section 32 and form an approximately right angle to the plate section 32. A window section 36 is provided on the plate section 32. The opening shape of the window section 36 is approximately the same as a display section of the medical instrument on which the protective cover is fitted, and a user of the medical instrument can read a numerical figure or a message displayed on the display section from the window section 36. Also, an opening part 38 is provided on the plate section 32. The opening shape of the opening part 38 is approximately the same as the switch of the medical instrument, and thus, the user can operate the switch.
COPYRIGHT: (C)2005,JPO&NCIPI

76. 发明公开

EP2598534A1 ANTIBODIES RELATING TO PIVKA-II AND USES THEREOF 审中-公开
标题翻译：抗体在与PIVKA-II及其用途CONNECTION
公开(公告)号：EP2598534A1
公开(公告)日：2013-06-05
申请号：EP11738347.1
申请日：2011-07-08
申请人： Abbott Laboratories , Abbott Japan Co. Ltd.
发明人： YOSHIMURA, Toru , DOWELL, Barry L. , BELIGERE, Gangamani S. , YOSHIDA, Eisaku
IPC分类号： C07K16/40 , G01N33/574
CPC分类号： C07K16/36 , C07K16/44 , C07K2317/34 , C07K2317/92 , G01N33/57438
摘要： The present disclosure relates to antibodies and immunoassay methods for use in the diagnosis, treatment and prevention of hepatocellular carcinoma (HCC), liver cancer and related conditions.

77. 发明公开

EP3657174A1 USE OF LAMININ 2 FOR DIAGNOSING HEPATOCELLULAR CARCINOMA AND PANCREATIC CANCER 有权转让
公开(公告)号：EP3657174A1
公开(公告)日：2020-05-27
申请号：EP19219313.4
申请日：2016-09-28
申请人： Abbott Japan Co., Ltd. , The University of Tokyo
发明人： YOSHIMURA, Toru , YOSHIDA, Eisaku , KOSHIKAWA, Naohiko , SEIKI, Motoharu
IPC分类号： G01N33/574
摘要： Disclosed herein are biomarkers for hepatocellular carcinoma and pancreatic cancer. The biomarkers may be laminin gamma 2 monomer, PIVKA-II, AFP, CEA, CAI9-9, or combinations thereof. Also disclosed herein are methods of diagnosing, prognosing, classifying risk, and monitoring progression of hepatocellular carcinoma or pancreatic cancer by the detecting the level of laminin gamma 2 monomer, PIVKA-II, AFP, CEA, CAI9-9, or combinations thereof.

78. 发明公开

EP3577461A1 METHOD FOR REDUCING NOISE IN A SIGNAL-GENERATING DIGITAL ASSAYS 审中-实审转让
公开(公告)号：EP3577461A1
公开(公告)日：2019-12-11
申请号：EP18748418.3
申请日：2018-02-06
申请人： Abbott Japan Co., Ltd.
发明人： NAKAI FUTASE Atsuko
IPC分类号： G01N33/543

79. 发明公开

EP3559640A1 OPTICAL IMAGING SYSTEM USING LATERAL ILLUMINATION FOR DIGITAL ASSAYS 审中-实审
公开(公告)号：EP3559640A1
公开(公告)日：2019-10-30
申请号：EP17882684.8
申请日：2017-12-20
申请人： Abbott Japan Co. Ltd. , Ikeda, Tomohiro
发明人： IKEDA Tomohiro
IPC分类号： G01N21/64 , G01N21/03 , G01N21/51

80. 发明公开

EP3207160A2 SEQUENCE CONVERSION AND SIGNAL AMPLIFIER DNA HAVING LOCKED NUCLEIC ACIDS AND DETECTION METHODS USING SAME 有权转让
标题翻译：具有锁定核酸的序列转换和信号放大器DNA以及使用相同的检测方法
公开(公告)号：EP3207160A2
公开(公告)日：2017-08-23
申请号：EP15850599.0
申请日：2015-10-13
申请人： Abbott Japan Co. Ltd. , Tokyo Institute of Technology
发明人： KOMIYA, Ken , KOMORI, Makoto , TORU, Yoshimura
IPC分类号： C12Q1/68 , C12N15/00
摘要： Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide. Also disclosed are methods for detecting a target nucleic acid in a sample in which said sample is contacted, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide and a signal amplifier oligonucleotide. The disclosure also provides compositions and kits comprising such sequence conversion and signal amplifier oligonucleotides.
摘要翻译：公开了用于检测样品中的靶核酸的方法。所述方法包括使所述样品在聚合酶和内切核酸酶的存在下与序列转化寡核苷酸接触。还公开了在聚合酶和内切核酸酶的存在下用序列转换寡核苷酸和信号放大寡核苷酸检测其中所述样品接触的样品中的靶核酸的方法。本公开还提供了包含这种序列转换和信号放大寡核苷酸的组合物和试剂盒。

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