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    • 52. 发明申请
    • MEDICAL IMAGING DEVICE WITH SEPARATE BUTTON FOR SELECTING CANDIDATE SEGMENTATION
    • 具有分离按钮的医学成像装置,用于选择候选分类
    • US20140050304A1
    • 2014-02-20
    • US14114215
    • 2012-04-17
    • Raoul Florent
    • Raoul Florent
    • A61B6/00
    • A medical imaging device (10) allowing easy and robust representation of anatomic structures within a region of interest in a patient body is presented. The imaging device (10) comprises an image acquisition device (12), an image segmentation device (22), a visualization device (24) and a separate selection button (34). In an image of the region of interest, anatomic structures may be automatically identified using image segmentation techniques. Therein, not only one but a plurality of candidate images comprising differently identified anatomic structures is provided. The plurality of candidate images may be visualized on a display (26) sequentially or in an overlying manner. Using the easy accessible and easy to handle separate selection button (34), a physician may cycle through the plurality of candidate images and manually select one candidate image only by activating the selection button (34) for further exploitation. Thereby, automated segmentation techniques may be combined with the physician's experience thereby significantly increasing the robustness of a selected representation of anatomic structures while reducing human interaction to a minimum.
    • 呈现允许在患者体内感兴趣的区域内的解剖结构容易且鲁棒地表示的医学成像装置(10)。 成像装置(10)包括图像获取装置(12),图像分割装置(22),可视化装置(24)和单独的选择按钮(34)。 在感兴趣区域的图像中,可以使用图像分割技术自动识别解剖结构。 其中,不仅提供包括不同识别的解剖结构的一个但是多个候选图像。 多个候选图像可以在显示器(26)上顺序地或以重叠的方式可视化。 使用易于访问和容易处理的单独的选择按钮(34),医师可以循环通过多个候选图像,并且仅通过激活选择按钮(34)手动选择一个候选图像以供进一步利用。 因此,自动分割技术可以与医师的经验组合,从而显着增加所选择的解剖结构表示的鲁棒性,同时将人类交互作用降至最低。
    • 53. 发明申请
    • MEDICAL IMAGING DEVICE FOR PROVIDING AN IMAGE REPRESENTATION SUPPORTING IN POSITIONING AN INTERVENTION DEVICE
    • 医疗成像装置,用于提供支持定位干预装置的图像表示
    • US20130343631A1
    • 2013-12-26
    • US14003486
    • 2012-03-05
    • Raoul FlorentBart Pierre Antoine Jozef HoornaertHerman Stegehuis
    • Raoul FlorentBart Pierre Antoine Jozef HoornaertHerman Stegehuis
    • A61B5/00
    • A61B5/0037A61B6/06A61B6/12A61B6/4441A61B6/481A61B6/487A61B6/503A61B6/504A61B6/5229A61B6/542A61B90/37
    • A medical imaging device and a method for providing an image representation supporting positioning of an intervention device such as a wire tip (4) in a region of interest during an intervention is proposed. Therein, the following process steps are to be performed: (S1) acquiring a pre-live anatomy image (1) including a region of interest; (S2) acquiring a live anatomy image using a live image acquisition device comprising an adjustable collimator device; (S3) identifying a location (5) of the intervention device (4) within the live anatomy image; (S4) adjusting settings of the collimator device based on the identified location of the intervention device for subsequently acquiring a further live anatomy image representing the region of interest using the live image acquisition device with the collimator device being in the adjusted settings; and providing (S5) the image representation by merging information from the live anatomy image into the pre-live anatomy image. Thereby, the intervention device may be continuously tracked and the collimator device may restrict a field of view to a location of the intervention device thereby significantly reducing an applied X-ray dose. Background anatomical information may be introduced into the final image representation using the pre-live anatomy image possibly having a higher image contrast than the live anatomy images.
    • 提出了一种医疗成像装置和用于在干预期间提供支持在感兴趣区域中的诸如线尖(4)的介入装置的定位的图像表示的方法。 其中,执行以下处理步骤:(S1)获取包括感兴趣区域的活体前解剖图像(1); (S2)使用包括可调准直器装置的实况图像获取装置获取实况解剖图像; (S3)识别所述实况解剖图像内的介入装置(4)的位置(5); (S4)基于识别的干预装置的位置来调整准直仪装置的设置,用于随后使用准直仪装置处于调整的设置中的实时图像采集装置获取表示感兴趣区域的另外的活体解剖图像; 以及通过将来自实况解剖图像的信息合并到活体前解剖图像中来提供(S5)图像表示。 由此,干预装置可以被连续跟踪,并且准直器装置可以将视野限制到干预装置的位置,从而显着地减少施加的X射线剂量。 背景解剖信息可以使用可能具有比活体解剖图像更高的图像对比度的活体前解剖图像被引入最终图像表示。
    • 54. 发明授权
    • Mask construction for cardiac subtraction
    • 心脏减量的面罩构造
    • US08498463B2
    • 2013-07-30
    • US13058205
    • 2009-08-06
    • Raoul FlorentVincent Maurice Andre AuvrayOdile Bonnefous
    • Raoul FlorentVincent Maurice Andre AuvrayOdile Bonnefous
    • G06K9/00
    • A61B6/504A61B6/481A61B6/484A61B6/507A61B6/5264
    • To provide an improved method for achieving DSA images where the effect of residual motions in cardiac DSA during the perfusion phase is reduced and in order to display subtracted images containing less motion artefacts, a method of performing digital subtraction angiography DSA in an imaging apparatus comprises the steps of generating a first image sequence of mask images (10) of a subject to be examined, generating at least one first contrast image (22) at a first phase (16) whereby in the first contrast image part of the subject has a different contrast than in said first image sequence, subtracting the mask images (10) from the at least one first contrast image (22) generating a first DSA image sequence (24), subtracting the DSA images of the first DSA image sequence (24) from the first contrast image (22) within the first phase (16) generating a sequence of extended mask images (32); generating a second contrast image (34) with the imaging system at a second phase (18), said second phase (18) being separated from the first phase (16) by a predetermined phase dividing time limit (20), subtracting the images of the sequence of the extended mask images (32) from the second contrast image (34) generating a second DSA image sequence (38), displaying the second DSA image sequence (38) on a display (28).
    • 为了提供一种用于实现DSA图像的改进方法,其中在灌注阶段期间心脏DSA中的残留运动的影响减小,并且为了显示包含较少运动伪影的减影图像,在成像设备中执行数字减影血管造影DSA的方法包括 产生待检查对象的掩模图像(10)的第一图像序列的步骤,在第一阶段(16)产生至少一个第一对比图像(22),由此在对象的第一对比图像部分中具有不同的 与所述第一图像序列相比,从产生第一DSA图像序列(24)的至少一个第一对比图像(22)中减去掩模图像(10),从第一DSA图像序列(24)的DSA图像中减去第一DSA图像序列 第一相位(16)内的第一对比度图像(22)产生延伸的掩模图像序列(32); 在第二阶段(18)产生具有成像系统的第二对比度图像(34),所述第二相位(18)与预定的相位分割时间限制(20)从第一相位(16)分离,减去图像 来自第二对比度图像(34)的扩展掩模图像(32)的序列生成第二DSA图像序列(38),在显示器(28)上显示第二DSA图像序列(38)。
    • 55. 发明申请
    • 3D-ORIGINATED CARDIAC ROADMAPPING
    • 3D原版CARDIAC ROADMAPPING
    • US20130116551A1
    • 2013-05-09
    • US13810292
    • 2011-07-15
    • Raoul FlorentVincent AuvrayMichael GrassDirk SchaeferGert Schoonenberg
    • Raoul FlorentVincent AuvrayMichael GrassDirk SchaeferGert Schoonenberg
    • A61B6/02
    • A61B6/022A61B6/12A61B6/4441A61B6/463A61B6/487A61B6/504A61B6/5223A61B6/5235A61B2090/364A61B2090/367
    • The present invention relates to 3D-originated cardiac roadmapping. In order to improve the accuracy of the information provided to the user as navigation information, without any additional burden to the patient such as additional X-ray dose, a method is described comprising the steps of a) providing 3D+t image data of a vascular structure of an object; b) acquiring two-dimensional image data of the object, which object comprises the vascular structure, the 2D image data comprising at least one 2D image; c) projecting the vascular structure, thereby generating a plurality of mask images on the basis of a 3D+t image data; d) registering the at least one 2D image with one of the plurality of the mask images, wherein the registration comprises finding the maximum of a similarity factor between the mask images and the at least one 2D image; e) generating a combination of the at least one 2D image and a projection of the vascular structure on the basis of the 3D+t image data according to the registration; and f) displaying the combination as a guiding vessel tree projection. Thus improved cardiac roadmapping in form of a topographical roadmapping is provided since the roadmapping is based on three-dimensional data.
    • 本发明涉及3D起源的心脏路线图。 为了提高作为导航信息提供给用户的信息的准确性,对病人没有任何额外的负担,例如额外的X射线剂量,描述了一种方法,其包括以下步骤:a)提供一个 物体的血管结构; b)获取所述对象的二维图像数据,所述对象包括所述血管结构,所述2D图像数据包括至少一个2D图像; c)投影血管结构,从而基于3D + t图像数据生成多个掩模图像; d)使用所述多个掩模图像之一登记所述至少一个2D图像,其中所述注册包括找到所述掩模图像与所述至少一个2D图像之间的相似性因子的最大值; e)根据所述注册,基于所述3D + t图像数据生成所述至少一个2D图像和所述血管结构的投影的组合; 以及f)将组合显示为引导血管树投影。 因此,由于路线图基于三维数据,所以提供了形成路面图的形式的改进的心脏路线图。
    • 57. 发明申请
    • MASK CONSTRUCTION FOR CARDIAC SUBTRACTION
    • 用于心脏吸收的掩蔽结构
    • US20110305378A1
    • 2011-12-15
    • US13058205
    • 2009-08-06
    • Raoul FlorentVincent Maurice Andre AuvrayOdile Bonnefous
    • Raoul FlorentVincent Maurice Andre AuvrayOdile Bonnefous
    • G06K9/00
    • A61B6/504A61B6/481A61B6/484A61B6/507A61B6/5264
    • To provide an improved method for achieving DSA images where the effect of residual motions in cardiac DSA during the perfusion phase is reduced and in order to display subtracted images containing less motion artefacts, a method of performing digital subtraction angiography DSA in an imaging apparatus comprises the steps of generating a first image sequence of mask images (10) of a subject to be examined, generating at least one first contrast image (22) at a first phase (16) whereby in the first contrast image part of the subject has a different contrast than in said first image sequence, subtracting the mask images (10) from the at least one first contrast image (22) generating a first DSA image sequence (24), subtracting the DSA images of the first DSA image sequence (24) from the first contrast image (22) within the first phase (16) generating a sequence of extended mask images (32); generating a second contrast image (34) with the imaging system at a second phase (18), said second phase (18) being separated from the first phase (16) by a predetermined phase dividing time limit (20), subtracting the images of the sequence of the extended mask images (32) from the second contrast image (34) generating a second DSA image sequence (38), displaying the second DSA image sequence (38) on a display (28).
    • 为了提供一种用于实现DSA图像的改进方法,其中在灌注阶段期间心脏DSA中的残留运动的影响减小,并且为了显示包含较少运动伪影的减影图像,在成像设备中执行数字减影血管造影DSA的方法包括 产生待检查对象的掩模图像(10)的第一图像序列的步骤,在第一阶段(16)产生至少一个第一对比图像(22),由此在对象的第一对比图像部分中具有不同的 与所述第一图像序列相比,从产生第一DSA图像序列(24)的至少一个第一对比图像(22)中减去掩模图像(10),从第一DSA图像序列(24)的DSA图像中减去第一DSA图像序列 第一相位(16)内的第一对比度图像(22)产生延伸的掩模图像序列(32); 在第二阶段(18)产生具有成像系统的第二对比度图像(34),所述第二相位(18)与预定的相位分割时间限制(20)从第一相位(16)分离,减去图像 来自第二对比度图像(34)的扩展掩模图像(32)的序列生成第二DSA图像序列(38),在显示器(28)上显示第二DSA图像序列(38)。
    • 59. 发明授权
    • Image viewing system and method for generating filters for filtering image features according to their type
    • 图像查看系统和方法,用于根据其类型生成用于过滤图像特征的过滤器
    • US07738724B2
    • 2010-06-15
    • US10544204
    • 2004-02-03
    • Shérif Makram-EbeidRaoul Florent
    • Shérif Makram-EbeidRaoul Florent
    • H04N5/14H04N9/64
    • G06T5/20
    • Image processing system for generating a multidimensional adaptive oriented filter to be applied to the point intensities of a d-dimensional image, comprising analyzing means with means (5, fi) to estimate at each image point a probability measure (Fi) of the presence of a type of feature of interest and a weighting control model (10) issuing a weighting control vector (11, VC) constructed from said probability measure, for the user to control synthesized adaptive kernels at each image point; and synthesizing means for generating the filter kernels at each image point adapted to the type of the features of interest, whose filtering strength is controlled by the weighting control vector. The system may comprise a selection unit (40) for the user to select synthesizing means for generating “pre-mixing filtering means” comprising combining means (30, XH) dependent on the type of the image features having inputs for the weighting control vector (11, VC) and the image data [I(x)] and having an aspect for weighted adaptive kernels (35, H) adapted to the type of the image features to produce the filtered image signal [H(x)], and/or “post-mixing filtering means” comprising both isotropic and anisotropic filtering means [15, gi)] applied independently of the type of the image features, whose outputs (Gi) are combined at each image point and adapted using the weighting control vector (11, VC) to produce the filtered image signal [G(x)].
    • 图像处理系统,用于生成要应用于d维图像的点强度的多维自适应取向滤波器,包括具有用于在每个图像点处估计存在的概率测度(Fi)的装置(5,fi)的分析装置 一种感兴趣的特征的类型,以及发布由所述概率测量构成的加权控制向量(11,VC)的加权控制模型(10),用于在每个图像点处控制合成的自适应内核; 以及合成装置,用于在适于感兴趣特征的类型的每个图像点处产生滤波器核,其滤波强度由加权控制矢量控制。 该系统可以包括选择单元(40),用于用户选择合成装置,用于产生“预混合滤波装置”,该装置包括取决于具有用于加权控制矢量的输入的图像特征的类型的组合装置(30,XH) 11,VC)和图像数据[I(x)],并且具有适于图像特征的类型的加权自适应内核(35,H)的方面以产生滤波图像信号[H(x)],和/ 或“后混合滤波装置”,其包括独立于图像特征的类型的各向同性和各向异性滤波装置[15,gi]],其输出(Gi)在每个图像点被组合并且使用加权控制矢量 11,VC)以产生滤波图像信号[G(x)]。
    • 60. 发明授权
    • System and method for enhancing an object of interest in noisy medical images
    • 用于增强嘈杂医学图像中感兴趣对象的系统和方法
    • US07620221B2
    • 2009-11-17
    • US10543577
    • 2004-01-23
    • Raoul FlorentLucile NosjeanPierre Lelong
    • Raoul FlorentLucile NosjeanPierre Lelong
    • G06K9/00
    • A61B6/547A61B5/06A61B6/12A61B8/0833
    • The invention relates to a system and a method for detecting an object of interest in a sequence of medical images. Said viewing system comprises alarm detection means (20) for detecting a set of alarms of said object of interest in a medical image (I′) at time t, in which an alarms is a set of data describing a possible location of the object. It further comprise temporal tracking means (30) for iteratively creating a set of tracks (T′) at time t by associating alarms of said set of alarms (A′) with tracks (T′1) at time t−1 and for choosing a track from among said set of tracks at time t in accordance with a merit criterion. Said track at time t is ended by an alarm which corresponds to a detection of said object of interest in said medical image at time t. Said viewing system advantageously accumulates temporal proofs for confirming or infirming spatial detections of alarms at time t. Detection of the object of interest is therefore made more robust to errors.
    • 本发明涉及用于检测医学图像序列中感兴趣对象的系统和方法。 所述观察系统包括警报检测装置(20),用于在时间t检测医疗图像(I')中的所述感兴趣对象的一组警报,其中警报是描述对象的可能位置的一组数据。 它还包括时间跟踪装置(30),用于通过将所述报警组(A')的报警与时间t-1的轨道(T'1)相关联并且用于选择在时间t上迭代地创建一组轨道(T') 根据优点标准在时间t从所述一组轨道中的轨道。 在时间t的所述轨道由对应于在时间t的所述医学图像中的所述感兴趣对象的检测的报警结束。 所述观察系统有利地积累用于在时间t确认或弱化警报的空间检测的时间证据。 因此,感兴趣的对象的检测对于错误更加鲁棒。