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1. 发明授权

US10271808B2 Automatic positioning of absorption means in X-ray image acquisition 有权
公开(公告)号：US10271808B2
公开(公告)日：2019-04-30
申请号：US13636454
申请日：2011-03-24
申请人： Vincent Maurice Andre Auvray , Raoul Florent , Willem Frederik Den Hartog , Peter Willem Van Den Houten
发明人： Vincent Maurice Andre Auvray , Raoul Florent , Willem Frederik Den Hartog , Peter Willem Van Den Houten
IPC分类号： A61B6/06 , A61B6/00 , A61B6/03
摘要： The present invention relates to automatic absorption means positioning in X-ray image acquisition. To improve image quality and to optimize the radiation exposure of an object, optimal position for X-ray absorption means is provided. A first sequence (113) of X-ray images is acquired (112). For each of the images, the optimal position (115) for X-ray absorption means is determined (114). A second sequence (117) of X-ray images is associated 10 (116) with corresponding images of the first sequence. The determined optimal position for the absorption means (14) of the associated corresponding images of the first sequence (113) is selected for an acquisition of the second sequence (117). Hence, a situation-specific database with optimized positions for the absorption means is generated on behalf of the first sequence in order to provide the generated position information for the actual acquisition of a 15 second sequence of images.

2. 发明授权

US09053535B2 Adaptive roadmapping 有权
标题翻译：自适应路线图
公开(公告)号：US09053535B2
公开(公告)日：2015-06-09
申请号：US13810680
申请日：2011-07-15
申请人： Raoul Florent , Vincent Auvray , Michael Grass , Dirk Schaefer , Gert Schoonenberg
发明人： Raoul Florent , Vincent Auvray , Michael Grass , Dirk Schaefer , Gert Schoonenberg
IPC分类号： G06K9/00 , G06T7/00 , A61B6/12 , A61B6/00 , A61B19/00 , G06T19/00
CPC分类号： G06T7/0012 , A61B6/12 , A61B6/463 , A61B6/487 , A61B6/504 , A61B6/5235 , A61B90/37 , A61B2090/364 , A61B2090/365 , A61B2090/3764 , G06T7/32 , G06T19/00 , G06T2207/10121 , G06T2207/30101
摘要： An adaptive roadmapping device and method for examination of an object include providing pre-navigation image data representing part of the object being a vascular structure including an element of interest and having a tree-like structure with a plurality of sub-trees; generating a vessel representation based on the pre-navigation image data; acquiring live image data of the object; determining spatial relation of the pre-navigation image data and the live image data; analyzing the live image data by identifying and localizing the element in the live image data; determining a sub-tree in which the element is positioned, where the determining is based on the localization of the element and on the spatial relation; selecting a portion of the vascular structure based on the determined sub-tree; generating a combination of the live image data and an image of the selected portion of the vascular structure; and displaying the combination as a tailored roadmap.
摘要翻译：用于检查对象的自适应路线图设备和方法包括提供表示作为包括感兴趣元素并且具有多个子树的树状结构的血管结构的对象的一部分的导航前图像数据; 基于导航前图像数据生成船舶表示; 获取对象的实时图像数据; 确定所述导航前图像数据和实况图像数据的空间关系; 通过识别和定位实时图像数据中的元素来分析实况图像数据; 确定元素位于其中的子树，其中确定基于元素的定位和空间关系; 基于确定的子树选择血管结构的一部分; 生成活体图像数据和血管结构的所选部分的图像的组合; 并将该组合显示为定制的路线图。

3. 发明授权

US08923593B2 System and method for producing an image of a physical object 有权
标题翻译：用于产生物理对象的图像的系统和方法
公开(公告)号：US08923593B2
公开(公告)日：2014-12-30
申请号：US13636132
申请日：2011-03-18
申请人： Raoul Florent , Peter Willem Van Den Houten
发明人： Raoul Florent , Peter Willem Van Den Houten
IPC分类号： G06K9/00 , G06T7/00
CPC分类号： G06T7/003 , A61B6/12 , A61B6/4441 , A61B6/487 , A61B6/504 , A61B6/5288 , G06T7/337 , G06T2207/10121 , G06T2207/20224 , G06T2207/30052 , G06T2207/30101 , G06T2207/30204
摘要： The invention relates to a system and a method for producing an image of a physical object and to a computer program element and a computer readable medium. In order to provide improved stent boost subtract also showing wire state information, a system and a method are provided, the method comprising the following steps: a) tracking a predetermined first feature (126) and a predetermined second feature (128) in a first plurality (114) of first images (116), which images reveal a first criterion (118); and determining a first feature transform; and determining second feature distortion vector fields relative to the first feature transform; b) associating and recording second feature distortion vector fields corresponding to at least two phase attributes (120); c) tracking the predetermined first feature (126) in at least one secondary image (142) which image reveals a second criterion; d) determining a first-feature-based inter-criterion the first-feature-based inter-phase transform and the second feature distortion vector fields corresponding to a matching phase attribute (120); and f) generating a combined inter-criterion image (162) based on the restored physical distortion.
摘要翻译：本发明涉及一种用于产生物理对象和计算机程序元素和计算机可读介质的图像的系统和方法。为了提供也显示线状态信息的改进的支架升压减法，提供了一种系统和方法，该方法包括以下步骤：a）在第一个中跟踪预定的第一特征（126）和预定的第二特征（128）多个（114）的第一图像（116），哪些图像显示第一标准（118）; 以及确定第一特征变换; 以及确定相对于所述第一特征变换的第二特征失真向量场; b）关联和记录与至少两个相位属性（120）对应的第二特征失真向量域; c）在至少一个次要图像（142）中跟踪所述预定的第一特征（126），所述图像揭示第二准则; d）确定与基于匹配相位属性（120）相对应的基于第一特征的相间变换和第二特征失真向量场的基于第一特征的间标准; 以及f）基于恢复的物理失真产生组合的标准间图像（162）。

4. 发明授权

US08718349B2 Live registration for vessel treatment 有权
标题翻译：血管治疗的实时登记
公开(公告)号：US08718349B2
公开(公告)日：2014-05-06
申请号：US13387234
申请日：2010-09-22
申请人： Raoul Florent , Nicolaas Hylke Bakker
发明人： Raoul Florent , Nicolaas Hylke Bakker
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B5/02007 , A61B6/12 , A61B6/4441 , A61B6/463 , A61B6/466 , A61B6/481 , A61B6/5247 , A61B90/36 , A61B2090/364 , A61B2090/376 , G06T7/33 , G06T2207/10121 , G06T2207/30101
摘要： The present invention relates to accurate positioning for vessel intervention procedures, particularly to a method for accurate positioning for vessel intervention procedures, a medical imaging system for accurate positioning for vessel intervention procedures and a catheterization laboratory system for accurate positioning for vessel intervention procedures. First, at least one X-ray image of a vessel region of interest is acquired (24) with injected contrast agent. Further, vessel information data is identified (26) within the at least one acquired image. Then, first calcification features of the vessel in the vessel region of interest in the at least one acquired image are detected (28). Further, vessel representation is generated (30) using the vessel information data and the detected calcification features. Further, at least one current fluoroscopic image of the vessel region of interest is acquired (32). Then, second calcification features of the vessel in the vessel region of interest in the at least one current fluoroscopy image are detected (34), wherein the second calcification features are according to the first calcification features. Further, the vessel representation is registered (36) with the fluoroscopy image, wherein the calcification features are used for the registration. Then, a composite image is generated (38) by combining the vessel representation with the at least one fluoroscopy image. Further, a composite image is displayed (40).
摘要翻译：本发明涉及用于血管干预程序的精确定位，特别涉及用于容器干预程序的精确定位的方法，用于血管介入程序的精确定位的医学成像系统和用于血管干预程序的精确定位的导管实验室系统。首先，用注入的造影剂获取感兴趣的血管区域的至少一个X射线图像（24）。此外，在至少一个获取的图像内识别（26）船只信息数据。然后，检测在所述至少一个获取图像中的感兴趣的血管区域中的血管的第一钙化特征（28）。此外，使用血管信息数据和检测到的钙化特征产生（30）血管表示。此外，获取感兴趣血管区域的至少一个当前荧光透视图像（32）。然后，检测在所述至少一个当前荧光透视图像中的所述血管区域中的血管的第二钙化特征（34），其中所述第二钙化特征根据所述第一钙化特征。此外，用荧光透视图像记录（36）血管表示，其中钙化特征用于登记。然后，通过组合血管表示与至少一个荧光透视图来产生合成图像（38）。此外，显示合成图像（40）。

5. 发明授权

US08554308B2 Phase-free cardiac roadmapping 有权
标题翻译：无相位心脏路线图
公开(公告)号：US08554308B2
公开(公告)日：2013-10-08
申请号：US12528097
申请日：2008-02-25
申请人： Raoul Florent , Stephane Valente
发明人： Raoul Florent , Stephane Valente
IPC分类号： A61B5/00
CPC分类号： A61B6/504 , A61B6/12 , A61B6/4464 , A61B6/481 , A61B6/5235
摘要： According to an exemplary embodiment of the present invention, a cardiac roadmapping technique is provided, that does not rely on the prerequisite of a phase-centric pairing of the angiogram and life images. Instead, both the pairing and accurate registration of the images are combined within a single operation, for example by using a multi-device map. This may provide for robust and precise cardiac roadmapping.
摘要翻译：根据本发明的示例性实施例，提供了一种心脏路线图技术，其不依赖于血管造影和生命图像的以相位为中心配对的先决条件。相反，图像的配对和精确注册在单个操作中组合，例如通过使用多设备图。这可以提供鲁棒和精确的心脏路线图。

6. 发明申请

US20120190972A1 DEPTH DISAMBIGUATION OF INTERVENTIONAL INSTRUMENTS FROM A SINGLE X-RAY PROJECTION IMAGE AND ITS CALIBRATION 审中-公开
标题翻译：单次X射线投影图像的传统仪器的深度分析及其校准
公开(公告)号：US20120190972A1
公开(公告)日：2012-07-26
申请号：US13386925
申请日：2010-09-08
申请人： Pascal Cathier , Nicolas Pierre Bruno Gogin , Raoul Florent
发明人： Pascal Cathier , Nicolas Pierre Bruno Gogin , Raoul Florent
IPC分类号： A61B6/00 , G06K9/62
CPC分类号： A61B6/12 , A61B6/466 , G06T7/62 , G06T2207/10116 , G06T2207/30004
摘要： X-ray images are projective, meaning that the 3D geometry is flattened along projection lines going from the source to the detector. In particular procedures, such as mapping or ablation, the interventional instrument lies on the wall of the organ. Using a 3D segmentation of this organ registered to the x-ray, the instrument necessarily lies on the intersection of this surface with its projection line. The line and the surface typically intersect with a segmentation surface at a discrete number of points (typically 2 for shapes such as the anterior of the LA). One then has just to disambiguate between these different possible locations to determine the exact location of the instrument. In this invention, we propose to use the apparent width of the instrument measured in x-ray images to accomplish this task.
摘要翻译： X射线图像是投影的，这意味着沿着从源到检测器的投影线，3D几何图形被平坦化。特别是在绘图或消融过程中，介入器械位于器官的壁上。使用这个器官的3D分割记录到x射线，仪器必须位于该表面与其投影线的交点。线和表面通常与离散数量的点的分割表面相交（对于诸如LA的前部的形状，通常为2）。然后，您只需在这些不同的可能位置之间消除歧义，以确定仪器的确切位置。在本发明中，我们提出使用在x射线图像中测量的仪器的表观宽度来完成该任务。

7. 发明申请

US20120183189A1 VASCULAR ROADMAPPING 有权
公开(公告)号：US20120183189A1
公开(公告)日：2012-07-19
申请号：US13498162
申请日：2010-09-17
申请人： Raoul Florent , Pierre Lelong
发明人： Raoul Florent , Pierre Lelong
IPC分类号： G06K9/00
CPC分类号： A61B6/503 , A61B6/02 , A61B6/12 , A61B6/481 , A61B6/486 , A61B6/488 , A61B6/504 , A61B6/5235 , G06T5/50 , G06T7/0012 , G06T7/194 , G06T2207/10081 , G06T2207/10121 , G06T2207/30021 , G06T2207/30101
摘要： Cardiac roadmapping consists in correctly overlaying a vessel map sequence derived from an angiogram acquisition onto a fluoroscopy sequence used during PTCA intervention. This enhanced fluoroscopy sequence however suffers from several drawbacks such as breathing motion, high noise level, and most of all suboptimal contrast-enhanced mask due to segmentation defaults. This invention proposes to reverse the process and to locally overlay the intervention device as seen in fluoroscopy onto an optimal contrast-enhanced image of a corresponding cycle. This drastically reduces or suppresses the breathing motion, it provides the high image quality standard of angiograms, and avoids segmentation defaults. This proposal could lead to a brand new navigation practice in PCI procedures.
摘要翻译：心脏路线图包括将从血管造影获取导出的血管图谱顺序正确地覆盖在PTCA干预期间使用的荧光检查序列上。然而，这种增强的荧光透视序列具有诸如呼吸运动，高噪声水平以及由于分割默认值而导致的大多数次优对比度增强的掩模的几个缺陷。本发明提出了逆转该过程并将介入装置局部覆盖在荧光透视中观察到相应周期的最佳对比度增强图像上。这大大降低或抑制呼吸运动，提供血管造影图像的高图像质量标准，并避免分割默认值。这个建议可能导致PCI程序中的全新导航实践。

8. 发明申请

US20110305322A1 MEDICAL VIEWING SYSTEM FOR DISPLAYING A REGION OF INTEREST ON MEDICAL IMAGES 有权
标题翻译：用于显示医疗图像利益区域的医疗查看系统
公开(公告)号：US20110305322A1
公开(公告)日：2011-12-15
申请号：US13203266
申请日：2010-03-01
申请人： Peter Van Den Houten , Nicolaas Hylke Bakker , Raoul Florent , Vincent Maurice Andre Auvray
发明人： Peter Van Den Houten , Nicolaas Hylke Bakker , Raoul Florent , Vincent Maurice Andre Auvray
IPC分类号： H05G1/64 , G09G5/00
CPC分类号： A61B6/504 , A61B6/469 , A61B6/481 , G06T7/33 , G06T2207/10116 , G06T2207/30101
摘要： A medical viewing system with an X-ray image acquisition device for acquiring angiograms and interventional live images of vessels is adapted for generating a region of interest border into which an object referenced by an object-based registration process must extend in order to achieve an accurate registration of vessel trees extracted from the angiogram and the live images. The region of interest border is then overlaid onto the vessel tree images and the live images. The medical viewing system reminds the person accomplishing the intervention of the importance of pushing the object far enough into the image, while being discrete enough to be ignored if preferred, thus yielding in a reliable and precise road mapping processing.
摘要翻译：具有用于获取血管造影和血管介入实时图像的X射线图像获取装置的医学观察系统适于生成感兴趣区域边界，基于对象的注册过程所引用的对象必须延伸到该区域中以便实现准确注册从血管造影图像提取的血管树和实时图像。然后将兴趣区边界覆盖在船只树图像和实时图像上。医疗观察系统提醒人们完成对物体足够强的重要性的干预，同时足够离散以至于被忽视，如果是优选的，从而产生可靠和精确的道路测绘处理。

9. 发明申请

US20100049038A1 CARDIAC ROADMAPPING 有权
公开(公告)号：US20100049038A1
公开(公告)日：2010-02-25
申请号：US12529349
申请日：2008-02-25
申请人： Raoul Florent , Stephane Valente
发明人： Raoul Florent , Stephane Valente
IPC分类号： A61B5/05 , G06K9/00
CPC分类号： A61B6/481 , A61B6/12 , A61B6/504 , A61B6/5235 , A61B34/20 , A61B2034/107 , A61B2090/364 , A61B2090/376
摘要： According to an exemplary embodiment of the present invention, a cardiac roadmapping technique is provided, in which a static roadmap is built onto which a view of the intervention device is projected at the correct location. This new viewing mode combines the advantages of both roadmapping, i.e. accurate localization, and the advantages of a motion-free view, i.e. maximum readability.
摘要翻译：根据本发明的示例性实施例，提供了一种心脏路线图技术，其中建立了静态路线图，在该静态路线图上将干预装置的视图投影到正确的位置。这种新的观看模式结合了路线图的优点，即准确定位，以及无运动视图的优点，即最大可读性。

10. 发明申请

US20070276243A1 System for guiding a medical instrument in a patient body 有权
标题翻译：用于在患者体内引导医疗器械的系统
公开(公告)号：US20070276243A1
公开(公告)日：2007-11-29
申请号：US10596434
申请日：2004-12-17
申请人： Olivier Gerard , Raoul Florent , Geert Gijsbers
发明人： Olivier Gerard , Raoul Florent , Geert Gijsbers
IPC分类号： A61B8/08
CPC分类号： A61B19/20 , A61B6/12 , A61B6/463 , A61B6/469 , A61B6/5247 , A61B8/0833 , A61B8/0841 , A61B8/12 , A61B8/42 , A61B8/4227 , A61B8/4245 , A61B8/44 , A61B8/483 , A61B8/5238 , A61B8/5276 , A61B34/20 , A61B90/10 , A61B90/36 , A61B90/39 , A61B2034/2051 , A61B2090/365 , A61B2090/376 , A61B2090/378
摘要： The present invention relates to a system for guiding a medical instrument in a patient body. Such a system comprises means for acquiring a 2D X-ray image of said medical instrument, means for acquiring a 3D ultrasound data set of said medical instrument using an ultrasound probe, means for localizing said ultrasound probe in a referential of said X-ray acquisition means, means for selecting a region of interest around said medical instrument within the 3D ultrasound data set and means for generating a bimodal representation of said medical instrument detection by combining said 2D X-ray image and said 3D ultrasound data set. A bimodal representation is generated on the basis of the 2D X-ray image by replacing the X-ray intensity value of points belonging to said region of interest by the ultrasound intensity value of the corresponding point in the 3D ultrasound data set.
摘要翻译：本发明涉及一种用于引导患者体内的医疗器械的系统。这种系统包括用于获取所述医疗器械的2D X射线图像的装置，用于使用超声探头获取所述医疗器械的3D超声数据集的装置，用于在所述X射线获取的参考中定位所述超声探头的装置意味着用于在3D超声数据集内围绕所述医疗器械选择感兴趣区域的装置以及用于通过组合所述2D X射线图像和所述3D超声数据集来生成所述医疗仪器检测的双峰表示的装置。通过将属于所述感兴趣区域的点的X射线强度值替换为3D超声数据组中对应点的超声强度值，基于2D X射线图像生成双峰表示。

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