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    • 52. 发明授权
    • Undecapeptides containing cysteinesulfinic and cysteinesulfenic acid
    • 含有半胱氨酸和半胱氨酸的十一肽
    • US06617424B2
    • 2003-09-09
    • US09805548
    • 2001-03-14
    • Isao EndoMasafumi OdakaMasafumi YohdaMasayoshi NakasakoKoji Takio
    • Isao EndoMasafumi OdakaMasafumi YohdaMasayoshi NakasakoKoji Takio
    • C07K706
    • C07K7/06
    • Disclosed are peptides represented by IVC1SLC2SC3TAW and C1SLC2SC3 wherein I stands for isoleucine, V for valine, C1 for cysteine, C2 for cysteinesulfinic acid, C3 for cysteinesulfenic acid, S for serine, L for leucine, T for threonine, A for alanine, and W for tryptophan. These peptides can impart photoreactivity to a protein by binding to a non-heme iron. Also disclosed are methods for imparting photoreactivity to cells by introducing the peptide sequences into at least one protein which is involved in a metabolic system and/or energy metabolic system of the cells. There can be provided peptide sequences with a shorter peptide chain capable of imparting photoreactivity, which can be easily introduced into a protein with a little risk in degrading original function of the protein. There are also provided methods enabling control of metabolic reactions by imparting photoreactivity to cells with the peptides.
    • 公开的是由IVC1SLC2SC3TAW和C1SLC2SC3表示的肽,其中I代表异亮氨酸,V代表缬氨酸,C1代​​表半胱氨酸,C2代表半胱氨酸,C3代表半胱氨酸,S代表丝氨酸,L代表亮氨酸,T代表苏氨酸,A代表丙氨酸,W 用于色氨酸。 这些肽可以通过结合非血红素铁赋予蛋白质光反应性。 还公开了通过将肽序列引入参与细胞的代谢系统和/或能量代谢系统的至少一种蛋白质来赋予细胞光反应性的方法。 可以提供具有能够赋予光反应性的较短肽链的肽序列,其可以容易地引入蛋白质中,在降解蛋白质的原始功能方面几乎没有风险。 还提供了通过赋予细胞与肽的光反应性来控制代谢反应的方法。
    • 53. 发明授权
    • Hexapeptides containing cysteinsulfinic and cysteinesulfenic acid
    • 含有半胱氨酰亚砜和半胱氨酸的六肽
    • US06268475B1
    • 2001-07-31
    • US09113312
    • 1998-07-10
    • Isao EndoMasafumi OdakaMasafumi YohdaMasayoshi NakasakoKoji Takio
    • Isao EndoMasafumi OdakaMasafumi YohdaMasayoshi NakasakoKoji Takio
    • C07K706
    • C07K7/06
    • Disclosed are peptides represented by IVC1SLC2SC3TAW and C1SLC2SC3 wherein I stands for isoleucine, V for valine, C1 for cysteine, C2 for cysteinesulfinic acid, C3 for cysteinesulfenic acid, S for serine, L for leucine, T for threonine, A for alanine, and W for tryptophan. These peptides can impart photoreactivity to a protein by binding to a non-heme iron. Also disclosed are methods for imparting photoreactivity to cells by introducing the peptide sequences into at least one protein which is involved in a metabolic system and/or energy metabolic system of the cells. There can be provided peptide sequences with a shorter peptide chain capable of imparting photoreactivity, which can be easily introduced into a protein with a little risk in degrading original function of the protein. There are also provided methods enabling control of metabolic reactions by imparting photoreactivity to cells with the peptides.
    • 公开的是由IVC1SLC2SC3TAW和C1SLC2SC3表示的肽,其中I代表异亮氨酸,V代表缬氨酸,C1代​​表半胱氨酸,C2代表半胱氨酸,C3代表半胱氨酸,S代表丝氨酸,L代表亮氨酸,T代表苏氨酸,A代表丙氨酸,W 用于色氨酸。 这些肽可以通过结合非血红素铁赋予蛋白质光反应性。 还公开了通过将肽序列引入参与细胞的代谢系统和/或能量代谢系统的至少一种蛋白质来赋予细胞光反应性的方法。 可以提供具有能够赋予光反应性的较短肽链的肽序列,其可以容易地引入蛋白质中,在降解蛋白质的原始功能方面几乎没有风险。 还提供了通过赋予细胞与肽的光反应性来控制代谢反应的方法。
    • 56. 发明授权
    • Multi-color image forming apparatus having high developability without
fogging and without mixing of colors
    • 具有高显影性且无雾化且不混色的多色成像装置
    • US5701553A
    • 1997-12-23
    • US506389
    • 1995-07-24
    • Isao EndoToru KomatsuYotaro SatoHiroyuki NomoriKunio ShigetaMasahiro Onodera
    • Isao EndoToru KomatsuYotaro SatoHiroyuki NomoriKunio ShigetaMasahiro Onodera
    • G03G15/08G03G15/09G03G15/06
    • G03G15/09G03G15/0803G03G2215/0621
    • A development apparatus for developing a latent image formed on an image forming body with a developer so as to obtain a toner image. A developer conveyance unit conveys the developer, including a toner, to a development zone, between the developer conveyance unit and the image forming body, from an upstream side of the development zone in a conveyance direction to a downstream side thereof. A plate member having an electrode portion is positioned at the upstream side of the development zone, wherein a downstream end portion of the plate member is positioned in contact with the development zone. A power supply unit applies a first voltage, including a DC component and an AC component, to the developer conveyance unit so that an electric field is generated at the development zone. The power supply unit applies a second voltage, including a DC component, to the electrode portion of the plate member, and the plate member controls the electric field with the second voltage. The development apparatus satisfies: V.sub.AC >.vertline.V.sub.DEN .vertline.-.vertline.V.sub.DC .vertline. when an amplitude of the AC component of the first voltage is defined as V.sub.AC (volts), the DC component of the first voltage is defined as V.sub.DC (volts), and the DC component of the second voltage is defined as V.sub.DEN (volts). The development apparatus satisfies: 10.multidot..vertline.Qt.vertline..multidot.d.sub.t .multidot.D.sub.1 >V.sub.AC >5.multidot..vertline.Qt.vertline..multidot.d.sub.t .multidot.D.sub.2 when a closest distance from the developer conveyance unit to the image forming body is defined as D.sub.1 (mm), a closest distance from the developer conveyance unit to the electrode portion is defined as D.sub.2 (mm), an average charge-to-mass of the toner is defined as Qt (.mu.C/g), and an average particle size of the toner is defined as dt (.mu.m).
    • 一种用显影剂显影形成在图像形成体上的潜像以获得调色剂图像的显影装置。 显影剂输送单元将显影剂(包括调色剂)从显影区域的输送方向的上游侧向下游侧输送到显影剂输送单元和图像形成体之间的显影区域。 具有电极部分的板状部件位于显影区域的上游侧,其中板状部件的下游端部与显影区域接触。 电源单元将包括DC分量和AC分量的第一电压施加到显影剂输送单元,使得在显影区域产生电场。 电源单元将包括DC分量的第二电压施加到板构件的电极部分,并且板构件以第二电压来控制电场。 显影装置满足:VAC> | VDEN | - | VDC | 当第一电压的AC分量的振幅被定义为VAC(伏特)时,第一电压的直流分量被定义为VDC(伏特),并且第二电压的直流分量被定义为VDEN(伏特)。 当从显影剂输送单元到图像形成体的最近距离定义为D1(mm)时,显影装置满足:10x | Qt | xdtxD1> VAC> 5x | Qt | xdtxD2,距离显影剂输送单元至 电极部分定义为D2(mm),将调色剂的平均电荷质量定义为Qt(μC/ g),将调色剂的平均粒径定义为dt(μm)。