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41. 发明授权

US5677305A Oxopyridinylquinoxaline derivative 失效
标题翻译：氧吡嗪基喹喔啉衍生物
公开(公告)号：US5677305A
公开(公告)日：1997-10-14
申请号：US418196
申请日：1995-04-07
申请人： Susumu Takada , Nobuo Chomei , Makoto Adachi , Masami Eigyo , Kazuo Kawasaki
发明人： Susumu Takada , Nobuo Chomei , Makoto Adachi , Masami Eigyo , Kazuo Kawasaki
IPC分类号： C07D401/04 , C07D241/36 , A01N43/60 , C07D241/38
CPC分类号： C07D401/04
摘要： An oxopyridinylquinoxaline derivative represented by the following Formula I or pharmaceutically acceptable salts thereof: ##STR1## wherein R.sup.1 is hydrogen, halogen, nitro, or trihalomethyl; R.sup.2 is hydrogen, halogen, nitro, cyano, trihalomethyl, carbamoyl, carbamoyl substituted with lower alkyl, sulfamoyl, or sulfamoyl substituted with lower alkyl; R.sup.3 is hydrogen, nitro, or halogen; R.sup.4 is hydrogen, lower alkyl, substituted lower alkyl, lower cycloalkyl, or substituted lower cycloalkyl; R.sup.5 's are substituents independently selected from the group consisting of halogen, nitro, cyano, lower alkyl, carbamoyl, and carbamoyl substituted with lower alkyl; and n is an integer of 0 to 4. The derivative works as an antagonistic agent against both the NMDA receptors and the AMPA receptors, so that it is effective as a therapeutic agent for neurological disorders caused by excitatory amino acids binding to the receptors.
摘要翻译：由下式I表示的氧代吡啶基喹喔啉衍生物或其药学上可接受的盐：其中R 1是氢，卤素，硝基或三卤代甲基; R2是氢，卤素，硝基，氰基，三卤甲基，氨基甲酰基，被低级烷基取代的氨基甲酰基，氨磺酰基或被低级烷基取代的氨磺酰基; R3是氢，硝基或卤素; R4是氢，低级烷基，取代的低级烷基，低级环烷基或取代的低级环烷基; R 5是独立地选自卤素，硝基，氰基，低级烷基，氨基甲酰基和被低级烷基取代的氨基甲酰基的取代基。并且n为0至4的整数。该衍生物作为对NMDA受体和AMPA受体的拮抗剂起作用，因此其作为由与受体结合的兴奋性氨基酸引起的神经障碍的治疗剂是有效的。

42. 发明授权

US5509013A Multiplexer control system 失效
标题翻译：多路复用器控制系统
公开(公告)号：US5509013A
公开(公告)日：1996-04-16
申请号：US220271
申请日：1994-03-30
申请人： Makoto Adachi , Tetsuo Tachibana
发明人： Makoto Adachi , Tetsuo Tachibana
IPC分类号： H04J3/04 , H04J3/16 , H04J3/22 , H04L12/815 , H04L12/951 , H04Q11/04
CPC分类号： H04Q11/0478 , H04J3/1647 , H04J3/1682 , H04J3/22 , H04L2012/5672
摘要： A multiplexer control system is used to control multiplexing of data of a plurality of channels including channels having different transmission speeds. The multiplexer control system includes a bit map memory storing, in a bit map format, bits indicating existence of output timings respectively corresponding to different transmission speeds, a rate setting memory in which identification numbers indicating the transmission speeds are set in correspondence with the channels, and a controlling part for outputting an output timing signal depending on the transmission speed of the corresponding channel, based on the bit which indicates the existence of the output timing and is read by making access to the bit map memory and the identification number read by making access to the rate setting memory. The output timing signal determines the multiplexing of the data of the plurality of channels.
摘要翻译：复用器控制系统用于控制包括具有不同传输速度的信道的多个信道的数据的多路复用。多路复用器控制系统包括位图存储器，以比特图格式存储分别对应于不同传输速度的输出定时的位;比特设置存储器，其中指示传输速度的标识号码与信道相对应地设置，以及控制部分，用于基于指示输出定时的存在的位来输出取决于相应通道的传输速度的输出定时信号，并通过访问位图存储器和通过制作读取的识别号码来读取访问速率设置内存。输出定时信号确定多个通道的数据的复用。

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