专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明授权

US07006868B2 Method and apparatus for using a rest mode indicator to automatically adjust control parameters of an implantable cardiac stimulation device 失效
公开(公告)号：US07006868B2
公开(公告)日：2006-02-28
申请号：US10092695
申请日：2002-03-06
申请人： Joseph J. Florio , Gene A. Bornzin , Peter Boileau , Eric Falkenberg , Janice Barstad
发明人： Joseph J. Florio , Gene A. Bornzin , Peter Boileau , Eric Falkenberg , Janice Barstad
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61N1/37211
摘要： An implantable cardiac stimulation device is described wherein a controller of the cardiac stimulation device controls selected functions of the device based on whether the patient is at rest and further based on whether the patient is prone to vagally-mediated arrhythmias. Functions of the device that may be controlled include, for example, a pacing base rate, an AV/PV delay, and a refractory period as well as overdrive pacing parameters and diagnostic data gathering parameters. In one example, if the patient is not prone to vagally-mediated arrhythmias, the base rate is lowered while the patient is at rest. Also, overdrive pacing parameters are set to be less aggressive. As such, the operation of the cardiac stimulation device is controlled to make it easier for the patient to rest while also reducing power consumption. However, if the patient is prone to vagally-mediated arrhythmias, the base rate is not lowered while the patient is at rest. Overdrive pacing parameters are instead set to be more aggressive, rather than less aggressive. In this manner, the cardiac stimulation device attempts to compensate for any increased risk of arrhythmia that may occur while the patient, who is prone to vagally-mediated arrhythmias, is at rest. Numerous other parameters may be adjusted dependent upon whether the patient is at rest or dependent upon whether the patient is prone to vagally-mediated arrhythmias.

42. 发明授权

US06862471B1 Method and apparatus for blanking T-waves from combipolar atrial cardiac signals based on expected T-wave locations 有权
标题翻译：基于预期的T波位置从组合极心房心脏信号消隐T波的方法和装置
公开(公告)号：US06862471B1
公开(公告)日：2005-03-01
申请号：US10033254
申请日：2001-10-25
申请人： Kelly H. McClure , Joseph J. Florio , Gene A. Bornzin
发明人： Kelly H. McClure , Joseph J. Florio , Gene A. Bornzin
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452
摘要： The stimulation device blanks T-waves from the atrial channel of an electrical cardiac signal by employing a T-wave blanking interval localized to the expected location and duration of the T-wave. To this end, the stimulation device determines the average interval between an R-wave and a T-wave in the patient in which the device is implanted and also determines the average duration of a T-waves within the patient. A T-wave blanking interval is initiated following the average R-T interval subsequent to detection of an R-wave and lasts for a period of time equal to the average T-wave duration. In this manner, highly localized T-wave blanking is achieved permitting P-waves or other atrial signals to be detected during remaining non-blanked portions of the atrial channel of the cardiac signal at least for the purposes of atrial rate detection. The relatively short T-wave blanking interval of the invention is particularly well suited for use in combipolar sensing systems. Method and apparatus implementations are described.
摘要翻译：刺激装置通过采用局限于T波的预期位置和持续时间的T波消隐间隔来消除来自心电信号心房通道的T波。为此，刺激装置确定在其中植入装置的患者中的R波和T波之间的平均间隔，并且还确定患者内T波的平均持续时间。在检测到R波之后的平均R-T间隔之后开始T波消隐间隔，并且持续一段时间等于平均T波持续时间。以这种方式，实现高度局部化的T波消隐，允许在心脏信号的心房通道的剩余非消隐部分期间检测P波或其他心房信号，至少用于心房率检测。本发明的相对较短的T波消隐间隔特别适用于组合极检测系统。描述了方法和装置实现。

43. 发明授权

US06647295B2 Implantable cardiac stimulation device with detection and therapy for patients with vasovagal syncope 有权
公开(公告)号：US06647295B2
公开(公告)日：2003-11-11
申请号：US09849722
申请日：2001-05-03
申请人： Joseph J. Florio , Gregory Hauck , Gene A. Bornzin
发明人： Joseph J. Florio , Gregory Hauck , Gene A. Bornzin
IPC分类号： A61N1365
CPC分类号： A61N1/36514
摘要： A pacemaker or other implantable cardiac stimulation device is configured with both a rate hysteresis mode and a vasovagal syncope prevention mode. Within the rate hysteresis mode, the pacemaker detects when the intrinsic heart rate of the patient is below an escape rate, then paces the heart at a Base Rate until an intrinsic beat is detected. When programmed in the vasovagal syncope prevention mode, upon detecting the intrinsic rate falling below the Hysteresis Escape Rate, the pacemaker paces the heart at a Vasovagal Syncope Response Rate, which is considerably higher than the Base Rate. The pacemaker is preferably set to the syncope prevention mode for patients prone to recurrent vasovagal syncope. By pacing the heart at the higher Vasovagal Syncope Response Rate, the pacemaker thereby helps prevent a significant drop in blood pressure which might otherwise cause a loss of consciousness in the patient. System and method embodiments are described.

44. 发明授权

US06466821B1 AC/DC multi-axis accelerometer for determining patient activity and body position 失效
标题翻译：用于确定患者活动和身体位置的AC / DC多轴加速度计
公开(公告)号：US06466821B1
公开(公告)日：2002-10-15
申请号：US09457451
申请日：1999-12-08
申请人： Anne M. Pianca , Gene A. Bornzin , Euljoon Park , Joseph J. Florio , Alan B. Vogel , Lee Jay Mandell , Junyu Mai
发明人： Anne M. Pianca , Gene A. Bornzin , Euljoon Park , Joseph J. Florio , Alan B. Vogel , Lee Jay Mandell , Junyu Mai
IPC分类号： A61N1362
CPC分类号： A61N1/36542
摘要： An implantable cardiac stimulation device which determines stimulation based upon the patient's body position and activity level while eliminating special implantation or calibration procedures. To eliminate such special implantation and calibration procedures, the stimulation device correlates the patient's body position using a multi-axis DC accelerometer or other sensor during times of high activity and determines a patient's standing position value. During other times, the stimulation device compares the signals from the accelerometer to the standing position value to determine the patient's current body position. Based upon the current body position and the activity level, the stimulation device determines the necessary stimulation to deliver to the patient.
摘要翻译：一种可植入心脏刺激装置，其基于患者的身体位置和活动水平确定刺激，同时消除特殊植入或校准过程。为了消除这种特殊的植入和校准过程，刺激装置在高活动时间期间使用多轴DC加速度计或其他传感器来关联患者的身体位置并且确定患者的站立位置值。在其他时间，刺激装置将来自加速度计的信号与站立位置值进行比较，以确定患者的当前身体位置。基于当前身体位置和活动水平，刺激装置确定必要的刺激以递送给患者。

45. 发明授权

US5628779A Single-pass A-V pacing lead 失效
标题翻译：单程A-V起搏线
公开(公告)号：US5628779A
公开(公告)日：1997-05-13
申请号：US629960
申请日：1996-04-03
申请人： Gene A. Bornzin , Kevin L. Morgan , Joseph J. Florio , Wendy K. Wolsleger
发明人： Gene A. Bornzin , Kevin L. Morgan , Joseph J. Florio , Wendy K. Wolsleger
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A single-pass atrio-ventricular (A-V) pacing lead includes an elongated main lead body having an atrial electrode at the distal end thereof, and includes a ventricular branch which departs from the main lead body just proximal to the tip of the atrial electrode. The ventricular branch has a ventricular electrode at its distal tip. The main lead body includes a preformed "J"-shaped portion which, following proper implantation, projects the atrial electrode against a wall of the atrial appendage. The ventricular branch includes a preformed bend which curves in the opposite direction of the J-shaped portion so as to maintain the ventricular branch generally away from the wall of the atrial appendage. The lead includes a single lumen which extends through both the main lead body and the ventricular branch, allowing the lead to be implanted using a single stylet. When the styler is fully inserted within the lumen, an extension portion of the atrial electrode, including the electrode tip, rests alongside the straightened ventricular branch so as to present a low cross-sectional profile, facilitating transvenous implantation.
摘要翻译：单通道心房（A-V）起搏引线包括细长的主引线体，其在其远端具有心房电极，并且包括心室分支，该心室分支离开主导体正好靠近心房电极的尖端。心室分支在其远端具有心室电极。主引线体包括预成形的“J”形部分，其在适当植入之后将心房电极投射到心房的壁上。心室分支包括在J形部分的相反方向上弯曲的预成形弯曲部，以便使心室分支通常远离心房壁。引线包括延伸穿过主引线主体和心室分支的单个内腔，允许使用单个通丝针植入引线。当造型器完全插入管腔中时，包括电极末端的心房电极的延伸部分位于矫正的心室分支旁边，以便呈现低横截面轮廓，便于经静脉植入。

46. 发明授权

US5476483A System and method for modulating the base rate during sleep for a rate-responsive cardiac pacemaker 失效
标题翻译：用于在睡眠期间调节速率响应心脏起搏器的基本速率的系统和方法
公开(公告)号：US5476483A
公开(公告)日：1995-12-19
申请号：US258292
申请日：1994-06-10
申请人： Gene A. Bornzin , Elia R. Arambula , Joseph J. Florio
发明人： Gene A. Bornzin , Elia R. Arambula , Joseph J. Florio
IPC分类号： A61N1/365
CPC分类号： A61N1/36542
摘要： A system and method are provided for modulating the base rate of a transfer function for a rate-responsive cardiac pacemaker. Activity sensor measurements are used to derive activity variance measurements, which in turn are used to modulate the base pacing rate. In one embodiment, a histogram is used to store activity variance measurements collected over a period of about a week. The histogram is used to derive an activity variance threshold, which is compared to current activity variance measurements to determine if the patient is sleeping. If the patient is deemed to be sleeping, the pacing rate is set to a rate that comfortably meets the patient's low metabolic demands during sleep. In alternative embodiments, the activity variance measurements are applied to a base rate slope to modulate the base pacing rate.
摘要翻译：提供了一种用于调节速率响应心脏起搏器的传递函数的基本速率的系统和方法。活动传感器测量用于导出活动方差测量，反过来用于调节基础起搏率。在一个实施例中，直方图用于存储在大约一周的时间段内收集的活动方差测量。直方图用于导出活动方差阈值，其与当前活动方差测量值进行比较，以确定患者是否正在睡眠。如果患者被认为正在睡觉，则起搏速率设定为舒适地满足患者在睡眠期间的低代谢需求的速率。在替代实施例中，将活动方差测量值应用于基本速率斜率以调制基本起搏速率。

47. 发明授权

US08260404B1 Systems and methods for employing multiple filters to detect T-wave oversensing and to improve tachyarrhythmia detection within an implantable medical device 有权
标题翻译：使用多个滤波器来检测T波过度感知并改善可植入医疗装置内的快速性心律失常检测的系统和方法
公开(公告)号：US08260404B1
公开(公告)日：2012-09-04
申请号：US11776275
申请日：2007-07-11
申请人： Rupinder Bharmi , Jeffery D. Snell , Gene A. Bornzin , Joseph J. Florio , Peter Boileau
发明人： Rupinder Bharmi , Jeffery D. Snell , Gene A. Bornzin , Joseph J. Florio , Peter Boileau
IPC分类号： A61B5/0452 , A61B5/0456
CPC分类号： A61B5/0456 , A61B5/0464 , A61B5/725 , A61N1/3702 , A61N1/395
摘要： Techniques for detecting tachyarrhythmia and also for preventing T-wave oversensing use signals filtered by a narrowband bradycardia filter in combination with signals filtered by a narrowband tachycardia filter. A separate wideband filter may also be used.
摘要翻译：用于检测快速性心律失常并且还用于预防T波超检的技术使用由窄带心动过缓过滤器滤波的信号与由窄带心动过速过滤器过滤的信号组合。也可以使用单独的宽带滤波器。

48. 发明授权

US08180439B2 Ischemia detection using intra-cardiac signals 有权
标题翻译：使用心脏内信号的缺血检测
公开(公告)号：US08180439B2
公开(公告)日：2012-05-15
申请号：US12846387
申请日：2010-07-29
申请人： Jong Gill , Peter Boileau , Gene A. Bornzin , Joseph J. Florio , Mohssen Fard
发明人： Jong Gill , Peter Boileau , Gene A. Bornzin , Joseph J. Florio , Mohssen Fard
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/7203 , A61B5/7264 , Y10S128/92
摘要： An implanted cardiac rhythm management device is disclosed that is operative to detect myocardial ischemia. This is done by evaluating electrogram features to detect an electrocardiographic change; specifically, changes in electrogram segment during the early part of an ST segment. The early part of the ST segment is chosen to avoid the T-wave.
摘要翻译：公开了可用于检测心肌缺血的植入式心律管理装置。这通过评估电描记图特征来检测心电图变化来完成; 具体来说，在ST段的早期部分，电描绘片段的变化。选择ST段的早期部分以避免T波。

49. 发明申请

US20100094371A1 SYSTEMS AND METHODS FOR PAIRED/COUPLED PACING 有权
标题翻译：配对/连接的系统和方法
公开(公告)号：US20100094371A1
公开(公告)日：2010-04-15
申请号：US12635474
申请日：2009-12-10
申请人： Gene A. Bornzin , Joseph J. Florio
发明人： Gene A. Bornzin , Joseph J. Florio
IPC分类号： A61N1/365
CPC分类号： A61N1/3712 , A61N1/3627 , A61N1/36578
摘要： A coupled/paired stimulus pulse is delivered to the heart at an inter-pulse interval following one of i) detection of an intrinsic depolarization or ii) delivery of a primary stimulus pulse. Capture resulting from the coupled/paired stimulus pulse is sensed for. In response to capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally decreased by a first amount until there is no capture by a coupled/paired stimulus pulse. In response to no capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally increased by a second amount greater than the first amount, until capture by a coupled/paired stimulus pulse is detected. Once capture is again detected, paired/coupled pacing is delivered at the inter-pulse interval which resulted in capture for a predetermined period of time or until loss of capture occurs.
摘要翻译：耦合/配对的刺激脉冲按照i）检测到内部去极化或ii）主要刺激脉冲的传送之间的脉冲间隔递送到心脏。感测由耦合/配对刺激脉冲产生的捕获。响应于通过耦合/配对的刺激脉冲的捕获，脉冲间隔逐渐减小第一量，直到没有被耦合/配对的刺激脉冲捕获。响应于没有通过耦合/配对刺激脉冲的捕获，脉冲间隔逐渐增加大于第一量的第二量，直到检测到耦合/配对刺激脉冲的捕获。一旦再次检测到捕获，配对/联合起搏将以脉冲间隔传送，这导致捕获预定时间段或直到发生捕获丢失。

50. 发明授权

US07308306B1 System and method for dynamic ventricular overdrive pacing 有权
标题翻译：动态心室超速起搏的系统和方法
公开(公告)号：US07308306B1
公开(公告)日：2007-12-11
申请号：US10456060
申请日：2003-06-06
申请人： Euljoon Park , Peter Boileau , Joseph J. Florio , Gene A. Bornzin , Eric Falkenberg
发明人： Euljoon Park , Peter Boileau , Joseph J. Florio , Gene A. Bornzin , Eric Falkenberg
IPC分类号： A61N1/368
CPC分类号： A61N1/3621 , A61N1/365
摘要： Techniques are provided for overdrive pacing the ventricles using a pacemaker wherein an increase in an overdrive pacing rate is performed primarily to achieve a high degree of rate smoothing. The ventricles are paced at an overdrive pacing rate selected to permit the detection of the least some intrinsic ventricular pulses and then the overdrive pacing rate is dynamically adjusted based on the detected intrinsic ventricular pulses. In one example, an increase in the ventricular overdrive rate is performed only in response to detection of at least two intrinsic ventricular beats within a predetermined search period. If at least two intrinsic ventricular beats are not detected within the search period, the overdrive pacing rate is decreased. Various techniques are also provided for determining when to activate ventricular overdrive pacing depending, in part, on the capabilities of the particular pacemaker, the current mode of operation, the density of premature ventricular contractions, the degree of heart rate stability, and the presence of atrial fibrillation. Adaptive techniques for automatically adjusting ventricular overdrive pacing control parameters are also described.
摘要翻译：提供技术用于使用起搏器超速起搏心室，其中主要执行超速起搏速率的增加以实现高程度的速率平滑。心室以选择的超速起搏速度进行起搏，以允许检测至少一些内在的心室脉冲，然后基于检测到的内在心室脉冲来动态地调整超速起搏速率。在一个示例中，仅在响应于在预定搜索周期内检测到至少两个本征心室搏动来执行心室超速率的增加。如果在搜索期内未检测到至少两个内在心室搏动，则超速起搏速率降低。还提供了各种技术来确定何时激活心室过度起搏起搏，其部分取决于特定起搏器的能力，当前的手术方式，早期心室收缩的密度，心率稳定程度以及是否存在心房颤动。还描述了用于自动调节心室超速起搏控制参数的自适应技术。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式