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31. 发明授权

US4278577A Bis(sulfonamide) stabilizers for synthetic polymers 失效
标题翻译：用于合成聚合物的双（磺酰胺）稳定剂
公开(公告)号：US4278577A
公开(公告)日：1981-07-14
申请号：US171620
申请日：1980-07-23
申请人： John Song
发明人： John Song
IPC分类号： C08K5/43 , C08L91/00 , C07C143/79
CPC分类号： C08K5/43
摘要： Bis(sulfonamides) containing one or more hindered phenol groups are disclosed, as is their use as thermal stabilizers for polymers. Further stabilization results from combinations thereof with a thiodipropionate ester and a divalent metal salt of a carboxylic acid.
摘要翻译：公开了含有一个或多个受阻酚基团的双（磺酰胺），它们用作聚合物的热稳定剂。进一步的稳定化来自与硫代二丙酸酯和羧酸的二价金属盐的组合。

32. 发明授权

US4239699A Sulfonamidophenols, metal complexes thereof, and solutions containing such compounds for use in extraction of metal values 失效
标题翻译：磺酰胺苯酚，其金属络合物，以及含有用于提取金属价值的化合物的溶液
公开(公告)号：US4239699A
公开(公告)日：1980-12-16
申请号：US909224
申请日：1978-05-24
申请人： Kenneth D. MacKay
发明人： Kenneth D. MacKay
IPC分类号： C01G3/00 , C01G9/00 , C01G53/00 , C22B3/34 , C07C143/78 , B01D11/04 , C07C143/79
CPC分类号： C01G9/003 , C01G3/003 , C01G53/003 , C22B3/0031 , Y02P10/234
摘要： Certain sulfonamidophenols, metal complexes thereof and solutions of said compounds in essentially water-immiscible, liquid hydrocarbon solvents are disclosed. The sulfonamidophenols have the structural formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification and claims hereof. Particular metal values are recovered from their aqueous solutions by using sulfonamidophenols dissolved in essentially water-immiscible liquid hydrocarbon solvents. The extraction process involves contacting the metal value containing aqueous solution with the solution of sulfonamidophenol in essentially water-immiscible liquid hydrocarbon solvent and stripping the metal values from the loaded organic phase.
摘要翻译：公开了某些磺酰胺苯酚，其金属络合物和所述化合物在基本上与水不混溶的液体烃溶剂中的溶液。磺酰胺苯酚具有结构式：其中R 1，R 2，R 3和R 4如本说明书和权利要求书中所定义。通过使用溶解在基本上与水不混溶的液体烃溶剂中的磺酰胺酚从其水溶液中回收特定的金属值。提取过程包括使含金属含量的水溶液与基本上与水不混溶的液体烃溶剂中的磺酰胺基苯溶液接触并从负载的有机相中汽提金属值。

33. 发明授权

US4160807A Sulfonamido oximes, metal complexes thereof, and solutions containing such compounds for use in extraction of metal values 失效
标题翻译：磺胺肟，其金属络合物和含有这些化合物的溶液用于提取金属价值
公开(公告)号：US4160807A
公开(公告)日：1979-07-10
申请号：US90922678
申请日：1978-05-24
申请人： HENKEL CORP
发明人： VIRNIG MICHAEL J , MACKAY KENNETH D
IPC分类号： C01G3/00 , C01G9/00 , C01G51/00 , C01G53/00 , C22B3/34 , C07C143/78 , B01D11/04 , C07C143/79
CPC分类号： C22B3/0031 , C01G3/003 , C01G9/003 , C01G51/003 , C01G53/003 , Y02P10/234
摘要： Certain sulfonamido oximes, metal complexes thereof and solutions of said compounds in essentially water-immiscible, liquid hydrocarbon solvents are disclosed. The sulfonamido oximes have the general structural formula: wherein A, R1, R2 and R3 are as defined in the specification and claims hereof. Particular metal values are recovered from their aqueous solutions by using sulfonamido oximes dissolved in essentially water-immiscible liquid hydrocarbon solvents. The extraction process involves contacting the metal value containing aqueous solution with the solution of the sulfonamido oxime in essentially water-immiscible liquid hydrocarbon solvent and stripping the mertal values from the loaded organic phase.
摘要翻译：公开了某些磺酰胺肟，其金属络合物和所述化合物在基本上与水不混溶的液体烃溶剂中的溶液。亚磺酰氨基肟具有以下通式结构式：其中A，R 1，R 2和R 3如本说明书和权利要求中所定义。通过使用溶解在基本上与水不混溶的液体烃溶剂中的磺酰胺肟，从其水溶液中回收特定的金属值。提取过程包括将含金属含量的水溶液与磺酰胺肟的溶液在基本上与水不混溶的液体烃溶剂中接触并从负载的有机相中汽提出来的值。

34. 发明授权

US4160783A 4-Dedimethylamino-4-arylsulfonamido-5a,6-anhydrotetracyclines 失效
标题翻译： 4-二甲基氨基-4-芳基磺酰胺基-5a，6-脱水四环素
公开(公告)号：US4160783A
公开(公告)日：1979-07-10
申请号：US855496
申请日：1977-11-28
申请人： Marica Cakara , Slobodan Djokic , Zrinka Tamburasev
发明人： Marica Cakara , Slobodan Djokic , Zrinka Tamburasev
IPC分类号： A61K31/18 , A61K31/65 , C07C311/15 , C07C143/79
CPC分类号： A61K31/18 , A61K31/65 , C07C311/15
摘要： Novel 4-dedimethylamino-4-arylsulfonamido-5a,6-anhydrotetracyclines of the general formula I ##STR1## wherein R stands for C.sub.1 -C.sub.3 -alkyl, halogen or --NHCOR.sup.1, R.sup.1 being C.sub.1 -C.sub.3 -alkyl.
摘要翻译：通式Ⅰ的新型4-脱二甲基氨基-4-芳基亚磺酰基-5a，6-脱水四环素其中R代表C 1 -C 3烷基，卤素或-NHCOR 1，R 1是C 1 -C 3烷基。

35. 发明授权

US4157257A Benzenesulfonamide derivatives 失效
标题翻译：苯磺酰胺衍生物
公开(公告)号：US4157257A
公开(公告)日：1979-06-05
申请号：US837911
申请日：1977-09-29
申请人： Tetsuo Takematsu , Makoto Konnai , Hiroyoshi Omokawa
发明人： Tetsuo Takematsu , Makoto Konnai , Hiroyoshi Omokawa
IPC分类号： A01N41/06 , C07C311/15 , A01N9/14 , C07C143/79 , C07C143/82
CPC分类号： C07C255/00 , A01N41/06
摘要： A compound of the general formula ##STR1## wherein R.sub.0 represents an alkyl group optionally having a substituent selected from the class consisting of a cyano group, lower alkoxy groups and di-(lower alkyl)amino groups, a lower alkenyl group, or a lower alkynyl group; R.sub.1, R.sub.2 and R.sub.3, independently from each other, represent a hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group; R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8, independently from each other, represent a hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group; Y represents a group of the formula ##STR2## or a group of the formula ##STR3## in which one of R.sub.9 and R.sub.10 is a lower alkyl group and the other is a hydrogen atom or a lower alkyl group; with the proviso that when Y is the group ##STR4## and R.sub.0 represents an unsubstituted alkyl group, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 do not represent hydrogen atoms at the same time. The compounds of formula (I) are produced by the reaction of the corresponding benzenesulfonamide derivatives with the corresponding benzyl or benzoyl halides; the reaction of the corresponding benzenesulfonyl halides with the corresponding benzylamines or benzoyl amides; or by the alkylation, alkenylation or alkynylation of the corresponding compounds of formula (I) in which R.sub.0 is hydrogen. The compounds of formula (I) have superior selective herbicidal effects, and are useful as active ingredients of herbicides, especially those for application to aquatic rice paddies.
摘要翻译：通式（I）的化合物，其中R 0表示任选具有选自氰基，低级烷氧基和二 - （低级烷基）氨基的取代基的烷基，低级烯基，或低级炔基; R 1，R 2和R 3彼此独立地表示氢原子，卤素原子，低级烷基或低级烷氧基; R4，R5，R6，R7和R8彼此独立地表示氢原子，卤素原子，低级烷基或低级烷氧基; Y表示式为“IMAGE”的基团或其中R9和R10中的一个为低级烷基且另一个为氢原子或低级烷基的式“IMAGE”的基团; 条件是当Y为基团时，R 0表示未取代的烷基，R 4，R 5，R 6，R 7和R 8不同时表示氢原子。式（I）化合物通过相应的苯磺酰胺衍生物与相应的苄基或苯甲酰基卤化物的反应产生; 相应的苯磺酰卤与相应的苄胺或苯甲酰胺的反应; 或通过其中R 0是氢的相应的式（I）化合物的烷基化，烯基化或炔基化。式（I）的化合物具有优异的选择性除草效果，并且可用作除草剂的活性成分，特别是用于水稻的施用。

36. 发明授权

US4035421A N-(3,4,-dichlorophenyl)-2-phenylethenesulfonamide 失效
标题翻译： N-（3,4， - 二氯苯基）-2-苯基亚磺酰胺
公开(公告)号：US4035421A
公开(公告)日：1977-07-12
申请号：US668612
申请日：1976-03-19
申请人： Harry R. Snyder, Jr.
发明人： Harry R. Snyder, Jr.
IPC分类号： C07C311/15 , C07C143/79 , A61K31/18
CPC分类号： C07C311/15
摘要： Antibacterially active N-(3,4-dichlorophenyl)-2-phenylethenesulfonamide.
摘要翻译：抗菌活性N-（3,4-二氯苯基）-2-苯基亚磺酰胺。

37. 发明授权

US3987095A N-substituted-1-(arylsulfinyl and arylsulfonyl)methanesulfonamides 失效
标题翻译： N-取代-1-（芳基磺酰基和芳基磺酰基）甲磺酰胺
公开(公告)号：US3987095A
公开(公告)日：1976-10-19
申请号：US465035
申请日：1974-04-29
申请人： Christian T. Goralski , Thomas C. Klingler
发明人： Christian T. Goralski , Thomas C. Klingler
IPC分类号： C07D295/26 , C07C143/75 , A61K31/18 , C07C143/79
CPC分类号： C07D295/26
摘要： The compounds of the formula ##SPC1##In which R independently is hydrogen, lower alkyl, lower alkoxy, halo or trifluoromethyl; x is 1 to 2; n is 1 to 3, and R.sub.1 and R.sub.2 independently are hydrogen, lower alkyl or phenyl and together with the nitrogen atom form a heterocycle which may contain an oxygen atom as a hetero atom. The compounds are prepared by reacting the corresponding N-substituted-1-(arylthio)methanesulfonamide with small, incremental amounts up to substantially equimolar of 30% hydrogen peroxide in glacial acetic acid at 65.degree.-70.degree. C., to obtain the sulfinyl compound, or substantially two equimolar proportions of 30% hydrogen peroxide in glacial acetic acid at reflux temperature to obtain the sulfonyl compound, and recovering the corresponding sulfinyl or sulfonyl product.

38. 发明授权

EP0226636B1 NEUE CARBONSÄUREDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG, IHRE VERWENDUNG SOWIE ARZNEIMITTEL, DIE DIESE VERBINDUNGEN ENTHALTEN 失效
标题翻译：新型羧酸衍生物及其制备方法，使用和含有这些化合物的药物
公开(公告)号：EP0226636B1
公开(公告)日：1989-02-08
申请号：EP86904797.7
申请日：1986-07-10
申请人： BOEHRINGER MANNHEIM GMBH
发明人： WOLFF, Hans, Peter , WITTE, Ernst-Christian , KÜHNLE, Hans-Frieder
IPC分类号： C07C147/06 , C07C143/68 , C07C149/273 , C07C147/14 , C07C143/79 , C07C103/24 , C07C69/65 , A61K31/49 , A61K31/215 , A61K31/275 , A61K31/255
CPC分类号： C07C317/00 , A61K31/19 , A61K31/215 , A61K31/255 , A61K31/275 , C07C59/64 , C07C59/68 , C07C59/88 , C07C309/00 , C07C323/00
摘要： New carboxylic acide derivatives having general formula (I) in which R1 is a possibly substituted aryl or aryloxy residue; R2 is hydrogen, a lower alkyl residue or the group R1-A-, as well as in the case where X represents the cyano group, an acylamino or amino group; A is a group of straight-chain or branched-chain, saturated or unsaturated alkyl group with 3 to 8 carbon atoms, which has a chain length of at least 3 carbon atoms; X represents the cyano group or a group of the formula -B-R3 or -D-NR4R5, in which B is O, S, SO, SO2, O(CO), OSO2, NHCO, NHSO2 or CO; D represents a valency dash, SO2 or CO; R3 is an alkyl, trifluoromethyl, cycloalkyl, aralkyl-, aralkenyl- or aryl group, in which the respective aryl residue can possibly be substituted; R4 is hydrogen, a lower alkyl residue, a possibly substituted aryl or aralkyl residue; R5 is hydrogen, a lower alkyl residue or R4 and R5 together are an alkyl chain with 4 to 6 carbon atoms which may be interrupted by O, S or NR6, and R6 is hydrogen, a lower alkyl residue or possibly a substituted phenyl or benzyl residue. Also described are their physiologically neutral salts, esters, amides and nitriles provided that in the case where: a) A is an alkyl group with 3 carbon atoms; a1) in all cases the aryl residue of the group R1 is not the unsubstituted phenyl residue and a2) X may not represent the groups -CN, NHCOR3 and NR4R5; b) where X is a residue of the formula -SCH3, R2 may not represent methyl; c) where X is the -NH2 or -NHCOCH3 group R1A- may not represent 4-phenylbutyl or 4-(4-methoxyphenyl)butyl; d) where X is the 2,4-dinitrophenyl group, R1A may not represent 4-phenylbutyl or 5-phenylpentyl; e) where X is the -COCH3 group, R1A may not represent 3-(2-chlorphenyl)propyl or 5-(4-methoxyphenyl)-pentyl. These compounds are used as medicines for lowering the sugar-level in the blood.

39. 发明授权

EP0158775B1 Substituted sulfonamidobenzamides, antiarrythmic agents and compositions thereof 有权
标题翻译：取代的磺酰胺类化合物，抗菌药物及其组合物
公开(公告)号：EP0158775B1
公开(公告)日：1988-04-20
申请号：EP85101112.2
申请日：1985-02-02
申请人： SCHERING AKTIENGESELLSCHAFT
发明人： Davey, David Daniel , Lumma, William Carl, Jr. , Wohl, Ronald André
IPC分类号： C07C143/72 , C07C143/75 , C07C143/77 , C07C143/79 , C07D295/12 , A61K31/165 , A61K31/395
CPC分类号： C07D295/13 , C07C255/00

40. 发明公开

EP0091749A3 Ethanolamine derivatives, process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：乙酰胺衍生物及其制备方法及含有它们的药物组合物
公开(公告)号：EP0091749A3
公开(公告)日：1984-12-05
申请号：EP83301652
申请日：1983-03-24
申请人： BEECHAM GROUP PLC
发明人： Duckworth, David Malcolm
IPC分类号： C07C143/78 , C07C143/79 , C07D295/22 , A61K31/18 , A61K31/445 , A61K31/535
CPC分类号： C07D295/26 , C07C309/00
摘要： AA compound of formula (I):
or a salt thereof, wherein;
R 1 is hydrogen, halogen or trifluoromethyl. R 2 is hydrogen or halogen, R 3 is hydrogen or methyl, R 4 is hydrogen or methyl, R 6 is hydrogen, C 1-10 straight or branched alkyl or optionally substituted benzyl, R 6 is hydrogen, C 1-10 straight or branched alkyl, or optionally substituted benzyl, or R 6 and R 6 taken together with the attached nitrogen atom represent a heterocyclic ring, R 7 is hydrogen or halogen, and n is 1 or 2;
are useful in the treatment of obesity and/or diabetes. Anti-hypertensive compounds of formula (I):
wherein
one of R 1 and R 2 is nitro, cyano or C 1-3 alkylcarbonyl, and the other is methoxy or amino optionally substituted by one or two C 1-6 alkyl or by C 2-7 alkanoyl; one of R 3 and R 4 is hydrogen or C 1-4 alkyl and the other is C 1-4 alkyl, or R 3 and R 4 together with the carbon atom to which they are attached are C 3-6 spiroalkyl; R 5 is hydrogen, C 1-3 alkyl or C 1-8 acyl; and n is 1 or 2; the lactam group being trans to the OR 5 group; or, when the other of R, and R 2 is amino, a pharmaceutically acceptable salt thereof.
摘要翻译：式（I）的化合物：或其盐，其中; R 1是氢，卤素或三氟甲基，R 2是氢或卤素，R 3是氢或甲基，R 4是氢或甲基，R 5是氢，C 1-10直链或支链烷基或任选取代的苄基，R 6是氢，C 1-10直链或支链烷基或任选取代的苄基，或R 5和R 6与连接的氮原子一起表示杂环R 7是氢或卤素，n是1或2; 可用于治疗肥胖和/或糖尿病。

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