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31. 发明授权

US5595473A Centrifugal fluid machine 失效
标题翻译：离心流体机
公开(公告)号：US5595473A
公开(公告)日：1997-01-21
申请号：US324212
申请日：1994-10-17
申请人： Yoshihiro Nagaoka , Sadashi Tanaka , Yukiji Iwase , Michiaki Ida , Hirotoshi Ishimaru , Saburo Iwasaki , Yoshiharu Ueyama , Tetuya Yoshida
发明人： Yoshihiro Nagaoka , Sadashi Tanaka , Yukiji Iwase , Michiaki Ida , Hirotoshi Ishimaru , Saburo Iwasaki , Yoshiharu Ueyama , Tetuya Yoshida
IPC分类号： F04D29/22 , F04D29/30 , F04D29/42 , F04D29/44 , F04D29/66 , F04D29/02
CPC分类号： F04D29/669 , F04D1/06 , F04D29/2216 , F04D29/422 , F04D29/428 , F04D29/444 , F04D29/448 , F04D29/661 , F04D29/663 , F05B2260/96 , F05D2240/121 , F05D2240/304 , F05D2250/52
摘要： At a vaned diffuser or a volute casing of a centrifugal fluid machine, pressure pulsation and vibrating forces acting upon the diffuser or the volute casing are mitigated or cancelled so as to abate the noise from the centrifugal fluid machine. The fluid machine having an impeller 3 rotating about a rotating shaft 2 within a casing 1 and having a vaned diffuser 4 or volute 12 fixed to the casing 1 is constructed such that radius of the vane trailing edge of the impeller 3 and radius of the vane leading edge of the diffuser 4 or radius of the volute tongue is varied in the direction of axis of rotation and inclinations, on a meridional plane, of the vane trailing edge of the impeller 3 and the vane leading edge of the diffuser 4 or the volute tongue are set in the same orientation, thereby reduction in head and efficiency or occurrence of an axial thrust may be restrained to the extent possible to optimally abate the noise and pressure pulsation of the centrifugal fluid machine.
摘要翻译：在离心式流体机械的叶片式扩散器或蜗壳上，作用在扩散器或蜗壳上的压力脉动和振动力被减轻或消除，从而减轻离心流体机器的噪音。具有围绕壳体1内的旋转轴2旋转并且具有固定到壳体1的带叶片扩散器4或蜗壳12的叶轮3的流体机构被构造成使得叶轮3的叶片后缘的半径和叶片的半径扩散器4的前缘或蜗壳舌的半径在叶轮3的叶片后缘和扩散器4的叶片前缘或蜗壳的经向平面上的旋转轴线和倾斜方向上变化舌头被设置在相同的方向上，从而可以在可能的程度上限制头部和效率的降低或轴向推力的发生，以最佳地消除离心式流体机械的噪声和压力脉动。

32. 发明授权

US07937990B2 Liquid chromatograph and separation column 失效
标题翻译：液相色谱仪和分离柱
公开(公告)号：US07937990B2
公开(公告)日：2011-05-10
申请号：US12037515
申请日：2008-02-26
申请人： Yoshihiro Nagaoka , Masahito Ito
发明人： Yoshihiro Nagaoka , Masahito Ito
IPC分类号： G01N30/50 , G01N30/60 , B01D15/08
CPC分类号： G01N30/6047
摘要： A separation column and a liquid chromatograph using the separation column, which are capable of carrying out a high-speed analysis under high pressure and without a reduction in separation performance of the separation column. In the separation column, a sample and a mobile phase are introduced into a packing material. The chromatograph has a covering member for covering an outer surface of the packing material and a supporting member having the packing material covered with the covering member inserted therein, wherein the level of pressure generated within a gap located between the covering member and the supporting member on the outflow side of the gap, where the fluid-flows out of the gap, is lower than that of pressure generated within the gap on the inflow side of the gap, where the fluid is introduced.
摘要翻译：分离塔和使用分离塔的液相色谱仪，其能够在高压下进行高速分析，而不会降低分离塔的分离性能。在分离塔中，将样品和流动相引入到包装材料中。色谱仪具有用于覆盖包装材料的外表面的覆盖部件和具有被插入其中的覆盖部件覆盖的包装材料的支撑部件，其中在覆盖部件和支撑部件之间的间隙内产生的压力水平液体流出间隙的间隙的流出侧低于在导入流体的间隙的流入侧的间隙内产生的压力的流出侧。

33. 发明授权

US07727472B2 Chemical analysis apparatus and chemical analysis cartridge 有权
标题翻译：化学分析仪和化学分析盒
公开(公告)号：US07727472B2
公开(公告)日：2010-06-01
申请号：US11319977
申请日：2005-12-29
申请人： Yoshihiro Nagaoka , Nobuyuki Maki , Noriyo Nishijima , Michihiro Saito , Hiroki Ihara
发明人： Yoshihiro Nagaoka , Nobuyuki Maki , Noriyo Nishijima , Michihiro Saito , Hiroki Ihara
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： G01N21/07 , G01N35/025 , G01N2035/00148 , G01N2035/00495 , Y10T436/11 , Y10T436/111666 , Y10T436/25
摘要： A chemical analysis apparatus comprises a motor, a holding disk that can be rotated by the motor, a plurality of examination cartridges arranged on the holding disk, a perforator that perforates the examination cartridges, a heating device, and a detection device. The examination cartridge comprises a substrate including a vessel and a flow channel, which are defined by recesses, and a cover that covers the vessel and the flow channel. A centrifugal force generated by rotation of the holding disk is made use of to move a solution from a vessel on an inner peripheral side relative to an axis of rotation to a vessel on an outer peripheral side relative to the axis of rotation through the flow channel.
摘要翻译：化学分析装置包括电动机，可由电动机旋转的保持盘，设置在保持盘上的多个检查盒，对检查筒进行穿孔的穿孔器，加热装置和检测装置。检查筒包括由凹部限定的容器和流路的基板和覆盖容器和流路的盖。通过保持盘的旋转而产生的离心力用于将溶液从相对于旋转轴线的内周侧的容器移动到通过流动通道相对于旋转轴线的外周侧上的容器。

34. 发明申请

US20090001007A1 SEPARATION COLUMN FOR LIQUID CHROMATOGRAPH APPARATUS AND LIQUID CHROMATOGRAPH APPARATUS USING THEREOF 失效
标题翻译：液相色谱仪和液相色谱仪的分离色谱柱
公开(公告)号：US20090001007A1
公开(公告)日：2009-01-01
申请号：US12146912
申请日：2008-06-26
申请人： Katsutoshi Shimizu , Masahito Ito , Kimihiko Ishii , Yoshihiro Nagaoka , Kisaburo Deguchi , Takefumi Yokokura
发明人： Katsutoshi Shimizu , Masahito Ito , Kimihiko Ishii , Yoshihiro Nagaoka , Kisaburo Deguchi , Takefumi Yokokura
IPC分类号： B01D15/08
CPC分类号： B01D15/22 , B01J20/282 , B01J2220/82 , B01J2220/825 , G01N30/22 , G01N30/6047 , G01N30/6052 , G01N30/6069 , G01N2030/522 , G01N2030/528
摘要： Both a column having high-pressure resistance and capable of performing high-speed separation and analysis even with a small flow rate and a liquid chromatograph apparatus using thereof are to be provided.A separation column according to the present invention has a monolithic rod being arranged in the center, being made of a porous material, and having a circular cross section, a filler layer arranged such that it encircles a circumferential surface of the monolithic rod, and a cylindrical support medium arranged outside the filler layer. The filler layer is formed by filling a tube-like gap between the monolithic rod and the support medium with particles or beads.
摘要翻译：提供具有高耐压性并且即使使用小流量也能够进行高速分离和分析的柱和使用其的液相色谱装置。根据本发明的分离柱具有中心的整体式杆，由多孔材料制成，并且具有圆形横截面，填充层布置成围绕整体式杆的圆周表面，并且圆柱形支撑介质布置在填充层外部。通过在颗粒或珠粒之间填充整体棒和支撑介质之间的管状间隙来形成填充层。

35. 发明申请

US20080245716A1 Separation column and liquid chromatography system with this column 审中-公开
标题翻译：分离柱和液相色谱系统
公开(公告)号：US20080245716A1
公开(公告)日：2008-10-09
申请号：US12076754
申请日：2008-03-21
申请人： Takeshi Ohura , Tomohiro Shoji , Daizo Tokinaga , Tomonari Morioka , Yoshihiro Nagaoka , Yoshitaka Kodama
发明人： Takeshi Ohura , Tomohiro Shoji , Daizo Tokinaga , Tomonari Morioka , Yoshihiro Nagaoka , Yoshitaka Kodama
IPC分类号： B01D15/08
CPC分类号： B01D15/22 , B01J2220/82 , G01N30/52 , G01N30/54 , G01N30/6052 , G01N30/606 , G01N30/88 , G01N2030/027 , G01N2030/528
摘要： A monolithic separation column and a liquid chromatography system using the same are provided by which the pressure tightness is improved, and the manufacturing is enabled at a low temperature, thus preventing the degradation of the separation performance. A monolithic rod 118 is made of a porous body and has a cylindrical shape. A coat material 116 coats an outer circumference of the monolithic rod 118 and includes an uneven portion 116R on an outer face thereof A holder 112, into which the monolithic rod 118 coated with the coat material 116 is inserted, includes a taper portion 112T on an inner face thereof. A potting media 114 is fitted or filled between the coat material 116 and the holder 112.
摘要翻译：提供了一种整体式分离柱和使用其的液相色谱系统，通过其提高了压力密封性，并且可以在低温下进行制造，从而防止分离性能的劣化。整体式杆118由多孔体制成并具有圆柱形状。涂层材料116涂覆整体式杆118的外周，并且在其外表面上包括不平坦部分116R，涂覆有涂层材料116的整体式杆118插入其中的保持器112包括锥形部分112T 在其内表面上。灌封介质114装配或填充在涂层材料116和保持器112之间。

36. 发明授权

US07273702B2 Apparatus for purifying nucleic acid and method of purifying nucleic acid 有权
标题翻译：核酸纯化装置及核酸纯化方法
公开(公告)号：US07273702B2
公开(公告)日：2007-09-25
申请号：US10478096
申请日：2002-05-24
申请人： Teruhisa Akashi , Yukiko Ikeda , Yoshihiro Nagaoka , Naruo Watanabe , Yuji Miyahara
发明人： Teruhisa Akashi , Yukiko Ikeda , Yoshihiro Nagaoka , Naruo Watanabe , Yuji Miyahara
IPC分类号： C12Q1/68 , C12M1/00 , C12M3/00 , C07H21/02
CPC分类号： B01L3/50273 , B01L3/5025 , B01L3/502738 , B01L3/502753 , B01L2200/027 , B01L2300/0803 , B01L2300/0867 , B01L2300/1827 , B01L2400/0409 , B01L2400/0694 , G01N35/00069 , G01N2030/381
摘要： A nucleic acid refining apparatus, being ease in automation thereof, keeping high in contacting frequency between nucleic acid within a sample and a solid phase during nucleic acid capture processing, thereby proving high capturing rate, comprises: means for separating a liquid containing the nucleic acid therein from said sample through centrifugal force; means for transferring a reagent through the centrifugal force; means for producing a mixture liquid of said reagent transferred through the centrifugal force and a solution containing said nucleic acid therein; a carrier for capturing said nucleic acid; means for transferring said mixture liquid to said carrier through the centrifugal force; heating means for heating said carrier; and a holding means for separating and holding the reagent containing said nucleic acid eluting from said carrier, separating from other reagent, through different centrifugal.
摘要翻译：一种核酸精制装置，其易于自动化，在核酸捕获处理期间保持样品内的核酸与固相之间的接触频率高，从而证明高捕获率，包括：用于分离含有核酸的液体的装置其中从所述样品通过离心力; 用于通过离心力转移试剂的装置; 用于生产通过离心力转移的所述试剂的混合液体的装置和其中含有所述核酸的溶液; 用于捕获所述核酸的载体; 用于通过离心力将所述混合液转移到所述载体的装置; 用于加热所述载体的加热装置; 以及用于分离并保持含有从所述载体洗脱的所述核酸的试剂的保持装置，通过不同的离心与其它试剂分离。

37. 发明申请

US20060159588A1 Chemical analysis device and chemical analysis cartridge 审中-公开
标题翻译：化学分析装置和化学分析盒
公开(公告)号：US20060159588A1
公开(公告)日：2006-07-20
申请号：US11319159
申请日：2005-12-28
申请人： Noriyo Nishijima , Yoshihiro Nagaoka , Toshiaki Yokobayashi , Michihiro Saito , Nobuyuki Maki , Satoshi Takahashi
发明人： Noriyo Nishijima , Yoshihiro Nagaoka , Toshiaki Yokobayashi , Michihiro Saito , Nobuyuki Maki , Satoshi Takahashi
IPC分类号： G01N9/30
CPC分类号： B01L3/502753 , B01L3/502723 , B01L3/502738 , B01L7/00 , B01L2200/10 , B01L2200/16 , B01L2300/0672 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688 , B01L2400/0694
摘要： A chemical analysis device has a motor, a holder disk to be rotated by the motor, a plurality of inspection cartridges, a penetrator for penetrating the inspection cartridges, a heater and a detector. The inspection cartridge has a substrate including containers formed as recesses and a flow path, and a cover is mounted on the substrate to cover the containers and flow path. By a centrifugal force generated by a rotation of the holder disk, a liquid is moved through the flow path from the container at a radially inner side with respect to a rotational axis to the container at a radially outer side with respect to the rotational axis.
摘要翻译：化学分析装置具有电动机，由电动机旋转的保持盘，多个检查筒，穿透检查筒的穿透器，加热器和检测器。检查盒具有包括形成为凹部和流路的容器的基板，并且在基板上安装盖以覆盖容器和流路。通过由保持盘旋转产生的离心力，使液体相对于旋转轴在径向外侧从相对于旋转轴的径向内侧的容器移动通过容器。

38. 发明授权

US06749397B2 Fluidal machine 失效
标题翻译：流苏机
公开(公告)号：US06749397B2
公开(公告)日：2004-06-15
申请号：US10305250
申请日：2002-11-27
申请人： Yoshiharu Ueyama , Michiyuki Takagi , Yasushi Takano , Yukiji Iwase , Michiaki Ida , Sadashi Tanaka , Yoshihiro Nagaoka , Tetsuya Yoshida
发明人： Yoshiharu Ueyama , Michiyuki Takagi , Yasushi Takano , Yukiji Iwase , Michiaki Ida , Sadashi Tanaka , Yoshihiro Nagaoka , Tetsuya Yoshida
IPC分类号： F04D2966
CPC分类号： F04D29/669 , F04D1/063 , F04D17/125 , F04D29/444 , F04D29/448 , F04D29/668
摘要： In a fluidal machine with an impeller rotating to urge a fluid radially outwardly by a centrifugal force, a vane guiding the fluid discharged from the impeller, a vane member which includes a front end of the vane facing to the impeller so that the fluid discharged from the impeller strikes against the front end and which is prevented from contacting the atmosphere, and a casing surrounding the vane member and contacting the atmosphere, the vane member is discrete from the casing, a vibration propagation between the vane member and the casing is prevented or restrained, and a vibration of a pipe extending from the casing is absorbed.
摘要翻译：在具有旋转的叶轮旋转以通过离心力径向向外推动流体的流体机器中，叶片引导从叶轮排出的流体，叶片构件包括叶片的前端面向叶轮，使得流体从叶轮撞击前端，防止与大气接触，围绕叶片构件并与大气接触的壳体，叶片构件与壳体分离，防止了叶片构件与壳体之间的振动传播，并且从壳体延伸出的管的振动被吸收。

39. 发明授权

US06500388B1 Automatically analyzing apparatus 有权
标题翻译：自动分析仪器
公开(公告)号：US06500388B1
公开(公告)日：2002-12-31
申请号：US09154698
申请日：1998-09-17
申请人： Yoshihiro Nagaoka , Ryo Miyake , Masaharu Nishida , Takeshi Shibuya , Takao Terayama , Hiroshi Mitsumaki
发明人： Yoshihiro Nagaoka , Ryo Miyake , Masaharu Nishida , Takeshi Shibuya , Takao Terayama , Hiroshi Mitsumaki
IPC分类号： G01N3510
CPC分类号： G01N35/02 , G01N2035/00376 , G01N2035/0437 , Y10T436/113332 , Y10T436/114998 , Y10T436/25625 , Y10T436/2575
摘要： An automatically analyzing apparatus includes a plurality of reaction containers for reacting a sample with a reagent, and a reaction container washing unit for washing the reaction containers through a plurality of washing steps. The reaction container washing unit includes a plurality of storage parts in each of which washing liquid containing therein reacted substance is reserved. The plurality of storage parts are sorted with different reacted substance concentrations. A supply part of the reaction container washing unit selects washing liquid of a desired reacted substance concentration among the plurality of storage parts in accordance with respective washing conditions of the reaction containers and supplies the selected washing liquid into the reaction containers for washing the respective reaction containers.
摘要翻译：自动分析装置包括用于使样品与试剂反应的多个反应容器和用于通过多个洗涤步骤洗涤反应容器的反应容器洗涤单元。反应容器洗涤单元包括多个储存部件，每个储存部件保留含有反应物质的洗涤液体。以不同的反应物质浓度对多个储存部分进行分选。反应容器洗涤单元的供应部分根据反应容器的各个洗涤条件选择多个储存部分中所需反应物质浓度的洗涤液，并将所选择的洗涤液供应到用于洗涤各反应容器的反应容器中。

40. 发明授权

US06364607B2 Centrifugal fluid machine 失效
标题翻译：离心流体机
公开(公告)号：US06364607B2
公开(公告)日：2002-04-02
申请号：US09853569
申请日：2001-05-14
申请人： Yoshihiro Nagaoka , Sadashi Tanaka , Yukiji Iwase , Michiaki Ida , Hirotoshi Ishimaru , Saburo Iwasaki , Yoshiharu Ueyama , Tetuya Yoshida
发明人： Yoshihiro Nagaoka , Sadashi Tanaka , Yukiji Iwase , Michiaki Ida , Hirotoshi Ishimaru , Saburo Iwasaki , Yoshiharu Ueyama , Tetuya Yoshida
IPC分类号： F01D102
CPC分类号： F04D29/669 , F04D1/06 , F04D29/2216 , F04D29/422 , F04D29/428 , F04D29/444 , F04D29/448 , F04D29/661 , F04D29/663 , F05B2260/96 , F05D2240/121 , F05D2240/304 , F05D2250/52
摘要： At a vaned diffuser or a volute casing of a centrifugal fluid machine, pressure pulsation and vibrating forces acting upon the diffuser or the volute casing are mitigated or cancelled so as to abate the noise from the centrifugal fluid machine. The fluid machine having an impeller 3 rotating about a rotating shaft 2 within a casing 1 and having a vaned diffuser 4 or volute 12 fixed to the casing 1 is constructed such that radius of the vane trailing edge of the impeller 3 and radius of the vane leading edge of the diffuser 4 or radius of the volute tongue is varied in the direction of axis of rotation and inclinations, on a meridional plane, of the vane trailing edge of the impeller 3 and the vane leading edge of the diffuser 4 or the volute tongue are set in the same orientation, thereby reduction in head and efficiency or occurrence of an axial thrust may be restrained to the extent possible to optimally abate the noise and pressure pulsation of the centrifugal fluid machine.
摘要翻译：在离心式流体机械的叶片式扩散器或蜗壳上，作用在扩散器或蜗壳上的压力脉动和振动力被减轻或消除，从而减轻离心流体机器的噪音。具有围绕壳体1内的旋转轴2旋转并且具有固定到壳体1的带叶片扩散器4或蜗壳12的叶轮3的流体机构被构造成使得叶轮3的叶片后缘的半径和叶片的半径扩散器4的前缘或蜗壳舌的半径在叶轮3的叶片后缘和扩散器4的叶片前缘或蜗壳的经向平面上的旋转轴线和倾斜方向上变化舌头被设置在相同的方向上，从而可以在可能的程度上限制头部和效率的降低或轴向推力的发生，以最佳地消除离心式流体机械的噪声和压力脉动。

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