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31. 发明申请

US20080269218A1 Novel Hsp90 Inhibitor 失效
标题翻译：新型Hsp90抑制剂
公开(公告)号：US20080269218A1
公开(公告)日：2008-10-30
申请号：US11885575
申请日：2006-03-08
申请人： Hiroshi Kuramochi , Setsuko Niitsuma , Masaharu Nakamura , Yoshitaka Sato , Seiichi Saito , Arihiro Tomura , Yuh-Ichiro Ichikawa , Yousuke Kasuga
发明人： Hiroshi Kuramochi , Setsuko Niitsuma , Masaharu Nakamura , Yoshitaka Sato , Seiichi Saito , Arihiro Tomura , Yuh-Ichiro Ichikawa , Yousuke Kasuga
IPC分类号： A61K31/5377 , C07D413/02 , A61K31/454 , A61K31/4196 , C07D249/12 , A61P35/00
CPC分类号： C07D249/12 , C07D249/14 , C07D401/12 , C07D403/12 , C07D405/12
摘要： Disclosed is a triazole derivative represented by the general formula (1) below or a pharmacologically acceptable salt thereof. Also disclosed are a prodrug of such a triazole derivative and an HSP90 inhibitor containing any one of them as an active constituent. (1) (In the formula, X represents a halogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group or the like; Y represents a mercapto group, a hydroxyl group, an optionally substituted sulfonyl group, an optionally substituted amino group or the like; and R represents an optionally substituted aryl or amino group or the like.)
摘要翻译：公开了由下述通式（1）表示的三唑衍生物或其药理学上可接受的盐。还公开了这种三唑衍生物的前体药物和含有它们中任何一种作为活性成分的HSP90抑制剂。（1）（式中，X表示卤原子，可以具有取代基的烷基，可以具有取代基的烯基等; Y表示巯基，羟基，可以具有取代基的磺酰基，可以具有取代基的氨基或类似物; R代表任选取代的芳基或氨基等）。

32. 发明申请

US20060197679A1 Signal transmission circuit, IC package, and mounting board 有权
公开(公告)号：US20060197679A1
公开(公告)日：2006-09-07
申请号：US11359510
申请日：2006-02-23
申请人： Keitaro Yamagishi , Seiichi Saito
发明人： Keitaro Yamagishi , Seiichi Saito
IPC分类号： G01V3/00
CPC分类号： H04L25/0298 , H01L2224/16225 , H01L2924/00011 , H01L2924/00014 , H01L2924/15311 , H01L2924/19105 , H04L25/0292 , H05K1/0237 , H05K1/0246 , H05K1/0298 , H05K2201/10022 , H05K2201/10734 , H01L2224/0401
摘要： Provided is a signal transmission circuit capable of realizing the same effects as those in a conventional manner that employs a complicated circuit by using no complicated circuit, that is, by a simple circuit. The signal transmission circuit includes: a transmission path having a first impedance; a terminating resistor having a predetermined resistance; a transmission path having a second impedance, which is connected to the transmission path and the terminating resistor, the second impedance being higher than both of the first impedance and the predetermined resistance; and an input buffer for receiving a signal at a connection portion of the transmission path and the transmission path.

33. 发明授权

US06384063B1 Compound having effect of promoting neuron differentiation 失效
标题翻译：具有促进神经元分化作用的化合物
公开(公告)号：US06384063B1
公开(公告)日：2002-05-07
申请号：US09463354
申请日：2000-03-31
申请人： Seiichi Saito , Masashi Nagai , Tomio Morino , Tsugio Tomiyoshi , Takaaki Nishikiori , Atsushi Kuwahara , Takamichi Sato , Takashi Harada
发明人： Seiichi Saito , Masashi Nagai , Tomio Morino , Tsugio Tomiyoshi , Takaaki Nishikiori , Atsushi Kuwahara , Takamichi Sato , Takashi Harada
IPC分类号： A61K3144
CPC分类号： C07D295/185 , C07C229/04 , C07C229/34 , C07C323/41 , C07C323/60 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07D205/04 , C07D207/16 , C07D213/32 , C07D213/50 , C07D213/55 , C07D295/145 , C07D295/155 , C07D295/192 , C07D307/54
摘要： A novel cystacycline derivative which has an excellent effect of promoting the differentiation of neurons and is useful as a remedy for central nervous system disorders, a remedy for peripheral nerve disorders, etc.
摘要翻译：一种新颖的胱天蛋白衍生物，其具有促进神经元分化的优异效果，并且可用作中枢神经系统疾病的补救剂，对于周围神经障碍的治疗等。

34. 发明授权

US5525645A Resin composition for optical molding 失效
标题翻译：用于光学成型的树脂组合物
公开(公告)号：US5525645A
公开(公告)日：1996-06-11
申请号：US417758
申请日：1995-04-06
申请人： Kazuo Ohkawa , Seiichi Saito
发明人： Kazuo Ohkawa , Seiichi Saito
IPC分类号： C08F2/46 , C08G59/68 , C08G65/10
CPC分类号： C08G59/68 , C08G65/105
摘要： The present invention relates to a resin composition for optical molding which comprises (a) an actinic radical-curable and cationically polymerizable organic substance and (b) an actinic radiation-sensitive initiator for cationic polymerization. This composition can be cured without being affected by atmospheric oxygen.
摘要翻译：本发明涉及一种光学成型用树脂组合物，其包含（a）光化自由基固化性和阳离子聚合性有机物质和（b）阳离子聚合用光化射线敏感性引发剂。该组合物可以在不受大气氧的影响的情况下固化。

35. 发明授权

US5434196A Resin composition for optical molding 失效
标题翻译：用于光学成型的树脂组合物
公开(公告)号：US5434196A
公开(公告)日：1995-07-18
申请号：US270058
申请日：1994-07-01
申请人： Kazuo Ohkawa , Seiichi Saito
发明人： Kazuo Ohkawa , Seiichi Saito
IPC分类号： C08F2/46 , C08G59/68 , C08G65/10
CPC分类号： C08G59/68 , C08G65/105
摘要： The present invention relates to a resin composition for optical molding which comprises (a) an actinic radical-curable and cationically polymerizable organic substance and (b) an actinic radiation-sensitive initiator for cationic polymerization. This composition can be cured without being affected by atomospheric oxygen.
摘要翻译：本发明涉及一种光学成型用树脂组合物，其包含（a）光化自由基固化性和阳离子聚合性有机物质和（b）阳离子聚合用光化射线敏感性引发剂。这种组合物可以在不受大气氧的影响的情况下固化。

36. 发明授权

US5283331A 2-halogeno-oxetanocin A and phosphoric ester thereof 失效
标题翻译： 2-卤代 - 氧杂环鸟素A及其磷酸酯
公开(公告)号：US5283331A
公开(公告)日：1994-02-01
申请号：US804773
申请日：1991-12-09
申请人： Seiichi Saito , Akira Masuda , Masayuki Kitagawa , Nobuyoshi Shimada , Jun-ichi Seki , Hiroo Hoshino , Yukihiro Nishiyama
发明人： Seiichi Saito , Akira Masuda , Masayuki Kitagawa , Nobuyoshi Shimada , Jun-ichi Seki , Hiroo Hoshino , Yukihiro Nishiyama
IPC分类号： A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7076 , A61P31/12 , C07H19/02 , C07H19/16 , C07D473/40 , A61K31/52 , C07F7/18 , C07F9/09
CPC分类号： C07H19/02
摘要： It was found that 2-halogeno-oxetanocin A and 4'-phosphate thereof represented by the following general formula (1): ##STR1## wherein X represents a halogen atom and R represents a hydrogen atom or a phosphoric acid residue ##STR2## or salts thereof exhibit a strong antiviral activity and are useful as an active ingredient of therapeutic drug for viral diseases. Further, it was also found that the compounds of this invention are characterized in that they are not inactivated by adenosine deaminase widely present in living bodies and exhibit a high residual activity.
摘要翻译：发现由以下通式（1）表示的2-卤代 - 氧杂环鸟菌素A和4'-磷酸酯：（*化学结构*）（1）其中X表示卤素原子，R表示氢原子或磷酸酸性残基（*化学结构*）或其盐表现出强的抗病毒活性，可用作病毒性疾病的治疗药物的活性成分。此外，还发现本发明的化合物的特征在于它们不被广泛存在于活体中的腺苷脱氨酶灭活，并且表现出高的残留活性。

37. 发明授权

US5003056A Antibiotic NK86-0279, process for production of the same and application of the same 失效
标题翻译：抗生素NK86-0279，生产过程相同，应用相同
公开(公告)号：US5003056A
公开(公告)日：1991-03-26
申请号：US288786
申请日：1988-12-22
申请人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamshita , Takako Tsuchiya , Takashi Harada
发明人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamshita , Takako Tsuchiya , Takashi Harada
IPC分类号： C07D493/20 , C07H19/01 , C12P17/18
CPC分类号： C07D493/20 , C07H19/01 , C12P17/181 , C12R1/465 , Y10S435/886
摘要： This invention relates to an antibiotic NK86-0279 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
摘要翻译：本发明涉及具有抗真菌，抗肿瘤，血管形成抑制和杀虫活性的下式的抗生素NK86-0279：。

38. 发明授权

US4994582A Novel antibiotic NK130119 失效
标题翻译：新型抗生素NK130119
公开(公告)号：US4994582A
公开(公告)日：1991-02-19
申请号：US466589
申请日：1990-01-17
申请人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamashita , Takashi Harada
发明人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamashita , Takashi Harada
IPC分类号： A01N43/90 , A61K31/365 , A61P31/04 , A61P31/10 , A61P35/00 , A61P43/00 , C07D493/18 , C07D493/20 , C12N1/20 , C12P17/18 , C12R1/465
CPC分类号： C07D493/20 , A01N43/90 , C12P17/181
摘要： This invention relates to an antibiotic NK130119 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.

39. 发明授权

US4992368A Novel process for producing oxetanocin G 失效
标题翻译：生产氧杂环丁霉素G的新方法
公开(公告)号：US4992368A
公开(公告)日：1991-02-12
申请号：US508910
申请日：1990-04-12
申请人： Seiichi Saito , Shigeru Hasegawa , Masayuki Kitagawa , Nobuyoshi Shimada , Noriyuki Yamashita
发明人： Seiichi Saito , Shigeru Hasegawa , Masayuki Kitagawa , Nobuyoshi Shimada , Noriyuki Yamashita
IPC分类号： C07H19/16 , C07D473/34 , C07H19/02
CPC分类号： C07H19/02
摘要： The present invention provides a novel process for producing oxetanocin G by hydrolysis of alkoxylated 2-amino-oxetanocin A thereby to convert ##STR1## at the 6-position thereof into >C.dbd.O. Oxetanocin G is expectedly useful as an antiviral agent.

40. 发明授权

US4707622A GaAs MESFET logic buffers using enhancement and depletion FETs 失效
标题翻译：使用增强和耗尽FET的GaAs MESFET逻辑缓冲器
公开(公告)号：US4707622A
公开(公告)日：1987-11-17
申请号：US815061
申请日：1985-12-31
申请人： Hisoka Takao , Toshiro Sato , Seiichi Saito , Toshinari Hayashi
发明人： Hisoka Takao , Toshiro Sato , Seiichi Saito , Toshinari Hayashi
IPC分类号： H03K19/0944 , H03K19/0952 , H03K19/094
CPC分类号： H03K19/09443 , H03K19/0952
摘要： A logic circuit includes an inverter circuit including a first enhancement type field effect transistor having a gate connected to an input, and a first depletion type transistor having a gate and a source which are directly connected to a drain of the first enhancement type field effect transistor. A source follower circuit including a second enhancement type field effect transistor having a gate is connected to a connecting point of the first enhancement type field effect transistor and the first depletion type field effect transistor. A second depletion type field effect transistor having a gate and a source which are directly connected to each other has a drain which is connected to a source of the second enhancement type field effect transistor. A first power source is connected to the drains of the first depletion type field effect transistor and the second enhancement type field effect transistor and a second power source is connected to the sources of the first enhancement type field effect transistor and the second depletion type field effect transistor. An output is formed at the connecting point of the second enhancement type field effect transistor and the second depletion type field effect type transistor.
摘要翻译：逻辑电路包括反相器电路，其包括具有连接到输入端的栅极的第一增强型场效应晶体管和具有栅极和源极的第一耗尽型晶体管，其直接连接到第一增强型场效应晶体管的漏极。包括具有栅极的第二增强型场效应晶体管的源极跟随器电路连接到第一增强型场效应晶体管和第一耗尽型场效应晶体管的连接点。具有彼此直接连接的栅极和源极的第二耗尽型场效应晶体管具有连接到第二增强型场效应晶体管的源极的漏极。第一电源连接到第一耗尽型场效应晶体管和第二增强型场效应晶体管的漏极，第二电源连接到第一增强型场效应晶体管的源极和第二衰减型场效应晶体管。在第二增强型场效应晶体管和第二耗尽型场效应晶体管的连接点处形成输出。

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