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1. 发明授权

US06384063B1 Compound having effect of promoting neuron differentiation 失效
标题翻译：具有促进神经元分化作用的化合物
公开(公告)号：US06384063B1
公开(公告)日：2002-05-07
申请号：US09463354
申请日：2000-03-31
申请人： Seiichi Saito , Masashi Nagai , Tomio Morino , Tsugio Tomiyoshi , Takaaki Nishikiori , Atsushi Kuwahara , Takamichi Sato , Takashi Harada
发明人： Seiichi Saito , Masashi Nagai , Tomio Morino , Tsugio Tomiyoshi , Takaaki Nishikiori , Atsushi Kuwahara , Takamichi Sato , Takashi Harada
IPC分类号： A61K3144
CPC分类号： C07D295/185 , C07C229/04 , C07C229/34 , C07C323/41 , C07C323/60 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07D205/04 , C07D207/16 , C07D213/32 , C07D213/50 , C07D213/55 , C07D295/145 , C07D295/155 , C07D295/192 , C07D307/54
摘要： A novel cystacycline derivative which has an excellent effect of promoting the differentiation of neurons and is useful as a remedy for central nervous system disorders, a remedy for peripheral nerve disorders, etc.
摘要翻译：一种新颖的胱天蛋白衍生物，其具有促进神经元分化的优异效果，并且可用作中枢神经系统疾病的补救剂，对于周围神经障碍的治疗等。

2. 发明授权

US5306496A Antibiotics NK374186A, NK374186B, NK374186B3 and NK374186C3, process for producing the same, and use of the same 失效
标题翻译：抗生素NK374186A，NK374186B，NK374186B3和NK374186C3，其制备方法及其用途
公开(公告)号：US5306496A
公开(公告)日：1994-04-26
申请号：US896676
申请日：1992-06-10
申请人： Tomio Morino , Masakazu Nishimoto , Mituyuki Nishide , Akira Masuda , Masatoshi Yamada , Eiji Kawano , Takaaki Nishikiori , Seiichi Saito
发明人： Tomio Morino , Masakazu Nishimoto , Mituyuki Nishide , Akira Masuda , Masatoshi Yamada , Eiji Kawano , Takaaki Nishikiori , Seiichi Saito
IPC分类号： C12P1/02 , A61K35/70
CPC分类号： C12P1/02
摘要： Novel antibiotics NK374186A, NK374186B, NK374186B3 and NK374186C3 having antibacterial, antineoplastic, immunomodulation, and liver regeneration promoting activities are provided.NK374186A, NK374186B, NK374186B3 and NK374186C3 are obtained by culturing NK374186 strain (FERM P-12285) (FERM-BP 3870) belonging to the genus Penicillium. NK374186A is a compound represented by a rational formula of C.sub.34 H.sub.61 N.sub.3 O.sub.12 S.sub.9 and having a molecular weight of M+ 735 (FD-MS m/z); NK374186B is a compound represented by a rational formula of C.sub.34 H.sub.61 N.sub.3 O.sub.9 and having a molecular weight of M+ 655 (FD-MS m/z); NK374186B3 is a compound represented by a rational formula of C.sub.34 H.sub.61 N.sub.3 O.sub.9 and having a molecular weight of M+ 655 (FD-MS m/z); and NK374186C3 is a compound represented by a rational formula of C.sub.32 H.sub.59 N.sub.3 O.sub.7 and having a molecular weight of M+ 597 (FD-MS m/z).
摘要翻译：提供具有抗菌，抗肿瘤，免疫调节和肝再生促进活性的新型抗生素NK374186A，NK374186B，NK374186B3和NK374186C3。通过培养属于青霉属的NK374186菌株（FERM P-12285）（FERM-BP 3870）获得NK374186A，NK374186B，NK374186B3和NK374186C3。 NK374186A是由C34H61N3O12S9的合理式表示的化合物，其分子量为M + 735（FD-MS m / z）; NK374186B是由合理式C34H61N3O9表示的化合物，分子量为M + 655（FD-MS m / z）; NK374186B3是由合成式C34H61N3O9表示的化合物，其分子量为M + 655（FD-MS m / z）; 并且NK374186C3是由合成式C32H59N3O7表示的化合物，其分子量为M + 597（FD-MS m / z）。

3. 发明授权

US5003056A Antibiotic NK86-0279, process for production of the same and application of the same 失效
标题翻译：抗生素NK86-0279，生产过程相同，应用相同
公开(公告)号：US5003056A
公开(公告)日：1991-03-26
申请号：US288786
申请日：1988-12-22
申请人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamshita , Takako Tsuchiya , Takashi Harada
发明人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamshita , Takako Tsuchiya , Takashi Harada
IPC分类号： C07D493/20 , C07H19/01 , C12P17/18
CPC分类号： C07D493/20 , C07H19/01 , C12P17/181 , C12R1/465 , Y10S435/886
摘要： This invention relates to an antibiotic NK86-0279 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
摘要翻译：本发明涉及具有抗真菌，抗肿瘤，血管形成抑制和杀虫活性的下式的抗生素NK86-0279：。

4. 发明授权

US4994582A Novel antibiotic NK130119 失效
标题翻译：新型抗生素NK130119
公开(公告)号：US4994582A
公开(公告)日：1991-02-19
申请号：US466589
申请日：1990-01-17
申请人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamashita , Takashi Harada
发明人： Takaaki Nishikiori , Masanori Yamazaki , Seiichi Saito , Nobuyoshi Shimada , Takashi Kurokawa , Kiyonobu Hirose , Takumi Yamashita , Takashi Harada
IPC分类号： A01N43/90 , A61K31/365 , A61P31/04 , A61P31/10 , A61P35/00 , A61P43/00 , C07D493/18 , C07D493/20 , C12N1/20 , C12P17/18 , C12R1/465
CPC分类号： C07D493/20 , A01N43/90 , C12P17/181
摘要： This invention relates to an antibiotic NK130119 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.

5. 发明授权

US5505944A Physiologically active substance NK175203, process for production thereof and pharmaceutical use thereof 失效
标题翻译：生理活性物质NK175203，其制备方法和药物用途
公开(公告)号：US5505944A
公开(公告)日：1996-04-09
申请号：US392841
申请日：1995-02-28
申请人： Tomio Morino , Ayako Nakatani , Masayuki Kitagawa , Masaya Sato , Takashi Harada , Seiichi Saito
发明人： Tomio Morino , Ayako Nakatani , Masayuki Kitagawa , Masaya Sato , Takashi Harada , Seiichi Saito
IPC分类号： C12P1/06 , C07G17/00 , C12P1/04 , A61K35/74 , C12N1/20
CPC分类号： C12P1/06 , Y10S435/886
摘要： Physiologically active substance NK175203 is produced by culturing bacteria belonging to the genus Streptomyces and capable of producing the physiologically active substance NK175203, and collecting the produced and accumulated substance. The physiologically active substance NK175203 is useful as an effective ingredient of a pharmaceutical composition for promoting proliferation of bone marrow cells.
摘要翻译： PCT No.PCT / JP93 / 01276 Sec。 371日期1995年2月28日 102（e）1995年2月28日PCT PCT 1993年9月8日PCT公布。出版物WO94 / 05679 日期：1994年3月17日。生理活性物质NK175203是通过培养属于链霉菌属的细菌产生的，能够生产生理活性物质NK175203，并收集生成和积累的物质。生理活性物质NK175203可用作促进骨髓细胞增殖的药物组合物的有效成分。

6. 发明授权

US6114364A 2,3-disubstituted cyclopentanone derivatives, process for producing the same, and medicinal use thereof 失效
标题翻译： 2,3-二取代环戊酮衍生物，其制备方法及其医药用途
公开(公告)号：US6114364A
公开(公告)日：2000-09-05
申请号：US117411
申请日：1998-10-05
申请人： Seiichi Saito , Tomio Morino , Kuniko Masuda
发明人： Seiichi Saito , Tomio Morino , Kuniko Masuda
IPC分类号： C07C49/517 , C07C62/26 , C07C323/22 , C07C323/41 , C07C323/59 , C07D213/80 , C07D239/38 , C07D317/22 , C07D317/72 , A61K31/44 , C07D213/60
CPC分类号： C07D213/80 , C07C323/22 , C07C323/41 , C07C323/59 , C07C49/517 , C07C62/26 , C07D239/38 , C07D317/22 , C07D317/72 , C07C2101/08
摘要： The present invention relates to a compound represented by the following general formula (1) ##STR1## (wherein X represents O, S, SO, SO.sub.2, or NH, Y is a substituted or unsubstituted hydrocarbon residue containing 1 through 6 carbon atoms and having an overall molecular weight of not less than 15 and not more than 400, and the hydrocarbon residue, when the residue is ring, may contain one or two hetero-atoms in the ring, and Z is a carboxyl group, a group derived therefrom or an aliphatic hydrocarbon residue having from 1 to 4 carbon atoms which may be substituted or unsabstituted) or a pharmacologically acceptable salt thereof (excluding (1R,2S)-2-[(2R)-(2-acetyl-amino-2-carboxyethyl)thiomethyl]-3-oxo-1-cyclopentane-carboxylic acid (cystacyclin)), a method for production thereof and a medicinal use thereof. The compound of the present invention is useful as a neuron differentiation accelerator.
摘要翻译： PCT No.PCT / JP97 / 00247 Sec。 371日期：1998年10月5日 102（e）日期1998年10月5日PCT 1997年1月31日PCT PCT。公开号WO97 / 28114 PCT 日期：1997年8月7日本发明涉及由以下通式（1）表示的化合物（其中X表示O，S，SO，SO 2或NH，Y是取代或未取代的含有1至6个碳原子的烃基并且总分子量不小于15且不大于400，并且当残基为环时，烃残基在环中可以含有一个或两个杂原子，Z为羧基，衍生自或其药理学上可接受的盐（不包括（1R，2S）-2 - [（2R） - （2-乙酰基 - 氨基-2- 羧乙基）硫代甲基] -3-氧代-1-环戊烷 - 羧酸（cystacyclin）），其制备方法及其医药用途。本发明的化合物可用作神经元分化促进剂。

7. 发明申请

US20140199040A1 OPTICAL FIBER 有权
标题翻译：光纤
公开(公告)号：US20140199040A1
公开(公告)日：2014-07-17
申请号：US14116384
申请日：2012-05-10
申请人： Kazuyuki Sohma , Tomoyuki Hattori , Takashi Sueyoshi , Seiichi Saito , Koichi Sakamaki
发明人： Kazuyuki Sohma , Tomoyuki Hattori , Takashi Sueyoshi , Seiichi Saito , Koichi Sakamaki
IPC分类号： G02B6/02
CPC分类号： G02B6/02395 , C03C25/106 , C03C25/40 , G02B6/4436
摘要： Provided is an optical fiber which is provided with heat resistance and productivity and in which a transmission loss is suppressed even in a high-temperature environment. It has, on an outer periphery of a glass fiber composed of a core part and a cladding part, a coating layer made by crosslinking an energy-curable resin composition containing a silicon compound, in which the silicon compound contained in the energy-curable resin composition of the coating layer as an outermost layer has a specified structure having a cyclic silicone site having an epoxy group and a linear silicone site, with the content of the cyclic silicone site in the compound being from 10 to 30% by mass.
摘要翻译：提供具有耐热性和生产率的光纤，即使在高温环境下也能抑制传输损失。在由芯部和包层部分构成的玻璃纤维的外周上，通过将含有硅化合物的能量固化树脂组合物交联而制成的涂层，其中包含在能量固化树脂中的硅化合物作为最外层的涂层的组成具有具有环氧基和环状硅氧烷部位的环状硅氧烷部位的特定结构，化合物中的环状硅氧烷部位的含量为10〜30质量％。

8. 发明授权

US08768519B2 Apparatus and method for controlling grille aperture ratios of a plurality of air transfer grilles 有权
标题翻译：用于控制多个空气传送格栅的格栅孔径比的装置和方法
公开(公告)号：US08768519B2
公开(公告)日：2014-07-01
申请号：US12782878
申请日：2010-05-19
申请人： Ikuro Nagamatsu , Junichi Ishimine , Seiichi Saito , Masahiro Suzuki , Tadashi Katsui , Yuji Ohba , Nobuyoshi Yamaoka , Akira Ueda , Yasushi Uraki
发明人： Ikuro Nagamatsu , Junichi Ishimine , Seiichi Saito , Masahiro Suzuki , Tadashi Katsui , Yuji Ohba , Nobuyoshi Yamaoka , Akira Ueda , Yasushi Uraki
IPC分类号： G05D23/00 , H05K7/20
CPC分类号： H05K7/20836
摘要： An apparatus for controlling grille aperture ratios of a plurality of air transfer grilles which are installed in a room, includes a determining unit for determining target grille air volumes of air blowing to the racks, for determining simulation air volumes of air blowing from the air transfer grilles on the basis of the target grille air volumes so that each of air of the target grille air volumes are blown to the racks, and for determining grille aperture ratios for each of the air transfer grilles on the basis of the plurality of simulation air volumes so that each of the amounts of air blowing from the air transfer grilles is replaced by each of the simulation air volumes, and a controller for controlling each of the grille aperture ratios of the air transfer grilles on the basis of each of the determined grille aperture ratios.
摘要翻译：一种用于控制安装在房间中的多个空气传送格栅的格栅孔径比的装置，包括：确定单元，用于确定向机架吹送的空气的目标格栅空气体积，用于确定从空气传送中吹出的空气的模拟空气体积基于目标格栅空气体积格栅，使得目标格栅空气体积的每个空气被吹送到机架，并且基于多个模拟空气体积确定每个空气传送格栅的格栅孔径比使得从空气传送格栅吹出的每个空气量被每个模拟空气量所取代;以及控制器，用于基于每个确定的格栅孔径来控制空气传送格栅的每个格栅孔径比比率。

9. 发明授权

US08063768B2 Modem apparatus 失效
标题翻译：调制解调器
公开(公告)号：US08063768B2
公开(公告)日：2011-11-22
申请号：US11792057
申请日：2005-04-14
申请人： Yoshihiro Akeboshi , Seiichi Saito , Mitsuhiro Shimozawa
发明人： Yoshihiro Akeboshi , Seiichi Saito , Mitsuhiro Shimozawa
IPC分类号： H04Q1/30
CPC分类号： H04B3/56 , H04B2203/5483
摘要： Provided is a modem apparatus of power line communication using a power line as a transmission path. The modem apparatus includes: an amplifier for amplifying communication signals and outputting a differential signal obtained from a pair of output signals having a phase difference of 180 degrees therebetween; a signal transformer for applying the amplified communication signals to the power lines; and a balance circuit connected at the primary side of the signal transformer, for enhancing circuit balancing. The balance circuit is constituted by a variable element capable of changing an element value, and there is provided a common mode detecting circuit that detects a common mode current flowing through the secondary side of the signal transformer and that changes the element value of the variable element of the balance circuit such that the detected common mode current becomes small.
摘要翻译：提供了使用电力线作为传输路径的电力线通信的调制解调器装置。调制解调器装置包括：放大器，用于放大通信信号并输出从具有180度相位差的一对输出信号获得的差分信号; 用于将放大的通信信号施加到电力线的信号变换器; 以及连接在信号变压器初级侧的平衡电路，用于增强电路平衡。平衡电路由能够改变元件值的可变元件构成，并且提供了共模检测电路，其检测流过信号变压器次级侧的共模电流，并且改变可变元件的元件值使得检测到的共模电流变小。

10. 发明授权

US08018784B2 Semiconductor device and data processor 有权
标题翻译：半导体器件和数据处理器
公开(公告)号：US08018784B2
公开(公告)日：2011-09-13
申请号：US12636528
申请日：2009-12-11
申请人： Yoshihiko Hotta , Seiichi Saito , Hiroyuki Hamasaki , Hirotaka Hara , Itaru Nonomura
发明人： Yoshihiko Hotta , Seiichi Saito , Hiroyuki Hamasaki , Hirotaka Hara , Itaru Nonomura
IPC分类号： G11C7/00 , G11C8/00
CPC分类号： G06F1/3253 , G06F1/3237 , Y02D10/128 , Y02D10/151
摘要： To improve the speed of accessing a low-speed circuit block from a high-speed circuit block without significantly increasing power consumption.Ina data processor having a bus controller that performs timing control of access from the CPU operated in synchronization with a high-speed first clock signal to a peripheral circuit operated in synchronization with a low-speed second clock signal, a timing control circuit is provided between the peripheral circuit and the bus controller, and the bus controller causes, in response to a read instruction from the peripheral circuit, the timing control circuit to output data held by the peripheral circuit to the bus controller in synchronization with the cycle of the high-speed clock signal, causes the timing control circuit to start, in response to a write instruction directed to the peripheral circuit, writing into the peripheral circuit in synchronization with the cycle of the high-speed clock signal, and terminates the writing in synchronization with the cycle of the low-speed clock signal.
摘要翻译：提高从高速电路块访问低速电路块的速度，而不会显着增加功耗。 Ina数据处理器具有总线控制器，其执行与高速第一时钟信号同步操作的CPU的访问定时控制到与低速第二时钟信号同步操作的外围电路，时序控制电路设置在外围电路和总线控制器以及总线控制器响应于来自外围电路的读取指令，使定时控制电路与外围电路的高周期同步地将外围电路保持的数据输出到总线控制器，响应于针对外围电路的写入指令，使定时控制电路开始与高速时钟信号的周期同步地写入外围电路，并且与该时钟信号同步地终止写入周期的低速时钟信号。

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