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    • 13. 发明授权
    • Interfacing nanostructures to biological cells
    • 将纳米结构与生物细胞接触
    • US08257932B2
    • 2012-09-04
    • US12034388
    • 2008-02-20
    • Xing ChenCarolyn R. BertozziAlexander K. Zettl
    • Xing ChenCarolyn R. BertozziAlexander K. Zettl
    • G01N33/53
    • C12N5/0006A61K47/549A61K47/58A61K47/61A61K47/6415A61K47/6949B82Y5/00C12N2501/59
    • Disclosed herein are methods and materials by which nanostructures such as carbon nanotubes, nanorods, etc. are bound to lectins and/or polysaccharides and prepared for administration to cells. Also disclosed are complexes comprising glycosylated nanostructures, which bind selectively to cells expressing glycosylated surface molecules recognized by the lectin. Exemplified is a complex comprising a carbon nanotube functionalized with a lipid-like alkane, linked to a polymer bearing repeated α-N-acetylgalactosamine sugar groups. This complex is shown to selectively adhere to the surface of living cells, without toxicity. In the exemplified embodiment, adherence is mediated by a multivalent lectin, which binds both to the cells and the α-N-acetylgalactosamine groups on the nanostructure.
    • 本文公开了纳米结构如碳纳米管,纳米棒等与凝集素和/或多糖结合并制备用于细胞的方法和材料。 还公开了包含糖基化纳米结构的复合物,其选择性结合表达由凝集素识别的糖基化表面分子的细胞。 示例性的是包含与脂质类烷烃官能化的碳纳米管的复合物,其与具有重复的α-N-乙酰半乳糖胺糖基团的聚合物连接。 该复合物显示出选择性地附着于活细胞表面,无毒性。 在示例性实施方案中,粘附是由多价凝集素介导的,其与纳米结构上的细胞和α-N-乙酰半乳糖胺基团结合。
    • 14. 发明申请
    • Inflatable Recreational Device
    • 充气娱乐装置
    • US20110212664A1
    • 2011-09-01
    • US13125612
    • 2009-06-09
    • Xing Chen
    • Xing Chen
    • A63H33/00
    • A63G31/12A63H33/00
    • An inflatable recreational device includes a first member and a plurality of second members, wherein the first member be a cylinder with an inner side and an outer side, and wherein the second members may be attached to the outer side thereof. The second members may form closed air chambers. A user may place him or herself within the first member for protection during use of the device. In another embodiment, a plurality of second members may form a cavity, without needing a first member, to protect the user.
    • 一种充气休闲装置包括第一构件和多个第二构件,其中第一构件是具有内侧和外侧的圆筒,并且其中第二构件可以附接到其外侧。 第二构件可以形成封闭的空气室。 用户可以在使用设备期间将他或她自己放置在第一个成员内进行保护。 在另一个实施例中,多个第二构件可以形成空腔,而不需要第一构件来保护使用者。