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11. 发明授权

US08478404B2 Output circuit for both cardiac contractile electrostimulation and non-contractile neural modulation 有权
标题翻译：输出电路用于心脏收缩电刺激和非收缩神经调制
公开(公告)号：US08478404B2
公开(公告)日：2013-07-02
申请号：US13099546
申请日：2011-05-03
申请人： Keith R. Maile , Ramprasad Vijayagopal , Nicholas J. Stessman , Firmin Musungu
发明人： Keith R. Maile , Ramprasad Vijayagopal , Nicholas J. Stessman , Firmin Musungu
IPC分类号： A61N1/00
CPC分类号： A61N1/362 , A61N1/36057 , A61N1/36114 , A61N1/36117 , A61N1/36125
摘要： An apparatus comprises an electrostimulation energy storage capacitor, a circuit path that provides pacing stimulation from the capacitor through the load, a constant current neural stimulation circuit that is switchable into the circuit path to provide neural stimulation through the load and switchable out of the circuit path to provide the pacing stimulation through the load, and a control circuit configured to selectively enable delivery of the pacing stimulation or the constant current neural stimulation.
摘要翻译：一种装置包括电刺激能量存储电容器，电路通过负载从电容器提供起搏刺激的恒定电流神经刺激电路，其可切换到电路路径中以通过负载提供神经刺激并且可从电路路径切换以通过负载提供起搏刺激，以及控制电路，其被配置为选择性地实现起搏刺激或恒定电流神经刺激的传递。

12. 发明授权

US08391992B2 Implantable medical device switching power supply including multiple modes 有权
标题翻译：植入式医疗器械开关电源包括多种模式
公开(公告)号：US08391992B2
公开(公告)日：2013-03-05
申请号：US12956375
申请日：2010-11-30
申请人： Michael J. Lyden , Nicholas J. Stessman
发明人： Michael J. Lyden , Nicholas J. Stessman
IPC分类号： A61N1/00
CPC分类号： A61N1/08
摘要： An implantable or other ambulatory medical device can include a magnetic field detector, such as configured to detect an intense magnetic field. In an example, the ambulatory or implantable medical device can include an inductive switching supply, such as including one or more of a peak current comparator, or a zero current comparator. In an example, the ambulatory or implantable medical device can include a controller circuit, configured to control a switch, such as to controllably charge an inductor included in the inductive switching supply.
摘要翻译：可植入或其他动态医疗装置可以包括磁场检测器，诸如被配置为检测强磁场。在一个示例中，移动或可植入的医疗设备可以包括感应开关电源，例如包括峰值电流比较器或零电流比较器中的一个或多个。在一个示例中，移动或可植入医疗装置可以包括控制器电路，其被配置为控制开关，例如可控制地对感应开关电源中包括的电感器充电。

13. 发明申请

US20090182389A1 MRI DETECTOR FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于可植入医疗器械的MRI检测器
公开(公告)号：US20090182389A1
公开(公告)日：2009-07-16
申请号：US12409766
申请日：2009-03-24
申请人： Nicholas J. Stessman
发明人： Nicholas J. Stessman
IPC分类号： A61N1/362
CPC分类号： A61N1/3718
摘要： An implantable medical device with an inductive switching regulator having an inductor with a ferromagnetic core is described. The device incorporates a core saturation detector for detecting saturation in the inductor core indicating the presence of a magnetic field such as produced by an MRI scan. The device is configured to alter its behavior when core saturation is detected such as by entering an MRI mode that may include cessation of therapy, fixed-rate bradycardia pacing, and/or disablement of tachyarrhythmia therapy.
摘要翻译：描述了具有感应开关调节器的可植入医疗装置，其具有带有铁磁芯的电感器。该装置包括用于检测电感器芯中的饱和度的核心饱和度检测器，指示存在诸如通过MRI扫描产生的磁场。该装置被配置为当检测到核心饱和时改变其行为，例如通过进入可以包括停止治疗，固定速率心动过缓起搏和/或停止快速性心律失常治疗的MRI模式。

14. 发明申请

US20090149905A1 CONFIGURATION OF PACING OUTPUT CHANNELS 有权
标题翻译： PACING输出通道的配置
公开(公告)号：US20090149905A1
公开(公告)日：2009-06-11
申请号：US12328603
申请日：2008-12-04
申请人： Michael J. Lyden , Nicholas J. Stessman
发明人： Michael J. Lyden , Nicholas J. Stessman
IPC分类号： A61N1/362
CPC分类号： A61N1/378 , A61N1/3706 , A61N1/371 , A61N1/3712 , A61N1/3716
摘要： During auto-threshold, autocapture, or other evoked response sensing, post-pace artifact is reduced by using a smaller coupling capacitor value than what is used when not in such an evoked response sensing configuration. This can be accomplished by borrowing another capacitor for use as the coupling capacitor. The borrowed capacitor can be a backup pacing capacitor from the same or a different pacing channel. The borrowed capacitor can also be a coupling capacitor from a different pacing channel.
摘要翻译：在自动阈值，自动拍摄或其他诱发响应感测期间，通过使用比不在这样的诱发响应感测配置中使用的耦合电容器值小的耦合电容器值来减小后期假想。这可以通过借用用作耦合电容器的另一个电容器来实现。借用的电容器可以是来自相同或不同起搏通道的备用起搏电容器。借用的电容器也可以是来自不同起搏通道的耦合电容器。

15. 发明申请

US20080097544A1 DYNAMIC BATTERY MANAGEMENT IN AN IMPLANTABLE DEVICE 有权
标题翻译：可移植设备中的动态电池管理
公开(公告)号：US20080097544A1
公开(公告)日：2008-04-24
申请号：US11551269
申请日：2006-10-20
申请人： Rajesh Krishan Gandhi , William J. Linder , Michael J. Lyden , Nicholas J. Stessman , Jonathan H. Kelly , James Kalgren
发明人： Rajesh Krishan Gandhi , William J. Linder , Michael J. Lyden , Nicholas J. Stessman , Jonathan H. Kelly , James Kalgren
IPC分类号： A61N1/00
CPC分类号： A61N1/378 , A61N1/3627 , A61N1/3708 , A61N1/3975
摘要： One aspect of this disclosure relates to a system for dynamic battery management in implantable medical devices. An embodiment of the system includes two or more devices for measuring battery capacity for an implantable medical device battery. The embodiment also includes a controller connected to the measuring devices. The controller is adapted to combine the measurements from the measuring devices using a weighted average to determine battery capacity consumed. According to various embodiments, at least one of the measuring devices includes a coulometer. At least one of the measuring devices includes a capacity-by-voltage device, according to an embodiment. The system further includes a display in communication with the controller in various embodiments. The display is adapted to provide a depiction of battery longevity in units of time remaining in the life of the implantable medical device battery, according to various embodiments. Other aspects and embodiments are provided herein.
摘要翻译：本公开的一个方面涉及用于可植入医疗装置中的动态电池管理的系统。该系统的实施例包括用于测量可植入医疗装置电池的电池容量的两个或更多个装置。该实施例还包括连接到测量装置的控制器。控制器适于使用加权平均值来组合来自测量装置的测量值，以确定消耗的电池容量。根据各种实施例，至少一个测量装置包括电量计。根据实施例，至少一个测量装置包括逐个电容装置。该系统还包括在各种实施例中与控制器通信的显示器。根据各种实施例，该显示器适于以可植入医疗装置电池的寿命中剩余的时间单位提供电池寿命的描绘。本文提供了其它方面和实施例。

16. 发明授权

US08694095B2 Configuration of pacing output channels 有权
标题翻译：起搏输出通道的配置
公开(公告)号：US08694095B2
公开(公告)日：2014-04-08
申请号：US12328603
申请日：2008-12-04
申请人： Michael J. Lyden , Nicholas J. Stessman
发明人： Michael J. Lyden , Nicholas J. Stessman
IPC分类号： A61N1/00
CPC分类号： A61N1/378 , A61N1/3706 , A61N1/371 , A61N1/3712 , A61N1/3716
摘要： During auto-threshold, autocapture, or other evoked response sensing, post-pace artifact is reduced by using a smaller coupling capacitor value than what is used when not in such an evoked response sensing configuration. This can be accomplished by borrowing another capacitor for use as the coupling capacitor. The borrowed capacitor can be a backup pacing capacitor from the same or a different pacing channel. The borrowed capacitor can also be a coupling capacitor from a different pacing channel.
摘要翻译：在自动阈值，自动拍摄或其他诱发响应感测期间，通过使用比不在这样的诱发响应感测配置中使用的耦合电容器值小的耦合电容器值来减小后期假想。这可以通过借用用作耦合电容器的另一个电容器来实现。借用的电容器可以是来自相同或不同起搏通道的后备起搏电容器。借用的电容器也可以是来自不同起搏通道的耦合电容器。

17. 发明授权

US08649862B2 Therapy circuit protection for implantable medical device 有权
标题翻译：可植入医疗器械的治疗电路保护
公开(公告)号：US08649862B2
公开(公告)日：2014-02-11
申请号：US13166297
申请日：2011-06-22
申请人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
发明人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/025 , A61N1/3706 , A61N1/3937 , A61N1/3962 , A61N2001/083
摘要： A medical device can include a therapy circuit configured to provide a specified electrostimulation therapy to a tissue site, the specified electrostimulation therapy including a scheduled completion, the therapy circuit including a protection circuit configured to adjust specification of the electrostimulation therapy being provided so as to provide an adjusted electrostimulation therapy before the scheduled completion. The medical device can include a monitoring circuit comprising a comparator. The monitoring circuit can be configured to trigger the protection circuit to inhibit the therapy circuit when the therapy circuit output parameter exceeds the specified threshold as indicated by the comparator.
摘要翻译：医疗设备可以包括治疗电路，其被配置为向组织部位提供特定的电刺激治疗，所述指定的电刺激治疗包括计划完成，所述治疗电路包括保护电路，该保护电路被配置为调整提供的电刺激治疗的规格，在计划完成之前进行调整的电刺激治疗。医疗装置可以包括包括比较器的监视电路。当比较器所指示的治疗电路输出参数超过指定的阈值时，监视电路可被配置为触发保护电路来抑制治疗电路。

18. 发明申请

US20120004694A1 THERAPY CIRCUIT PROTECTION FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：可植入医疗器械的治疗电路保护
公开(公告)号：US20120004694A1
公开(公告)日：2012-01-05
申请号：US13166297
申请日：2011-06-22
申请人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
发明人： Jacob M. Ludwig , William J. Linder , Douglas J. Brandner , Nicholas J. Stessman , Douglas Michael Hannan , Scott R. Stubbs , Jeffrey E. Stahmann , Arthur Foster
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/025 , A61N1/3706 , A61N1/3937 , A61N1/3962 , A61N2001/083
摘要： A medical device can include a therapy circuit configured to provide a specified electrostimulation therapy to a tissue site, the specified electrostimulation therapy including a scheduled completion, the therapy circuit including a protection circuit configured to adjust specification of the electrostimulation therapy being provided so as to provide an adjusted electrostimulation therapy before the scheduled completion. The medical device can include a monitoring circuit comprising a comparator. The monitoring circuit can be configured to trigger the protection circuit to inhibit the therapy circuit when the therapy circuit output parameter exceeds the specified threshold as indicated by the comparator.
摘要翻译：医疗设备可以包括治疗电路，其被配置为向组织部位提供特定的电刺激治疗，所述指定的电刺激治疗包括计划完成，所述治疗电路包括保护电路，该保护电路被配置为调整提供的电刺激治疗的规格，在计划完成之前进行调整的电刺激治疗。医疗装置可以包括包括比较器的监视电路。当比较器所指示的治疗电路输出参数超过指定的阈值时，监视电路可被配置为触发保护电路来抑制治疗电路。

19. 发明授权

US08055343B2 Dynamic battery management in an implantable device 有权
标题翻译：植入式设备中的动态电池管理
公开(公告)号：US08055343B2
公开(公告)日：2011-11-08
申请号：US11551269
申请日：2006-10-20
申请人： Rajesh Krishan Gandhi , William J. Linder , Michael J. Lyden , Nicholas J. Stessman , Jonathan H. Kelly , James Kalgren
发明人： Rajesh Krishan Gandhi , William J. Linder , Michael J. Lyden , Nicholas J. Stessman , Jonathan H. Kelly , James Kalgren
IPC分类号： A61N1/08
CPC分类号： A61N1/378 , A61N1/3627 , A61N1/3708 , A61N1/3975
摘要： One aspect of this disclosure relates to a system for dynamic battery management in implantable medical devices. An embodiment of the system includes two or more devices for measuring battery capacity for an implantable medical device battery. The embodiment also includes a controller connected to the measuring devices. The controller is adapted to combine the measurements from the measuring devices using a weighted average to determine battery capacity consumed. According to various embodiments, at least one of the measuring devices includes a coulometer. At least one of the measuring devices includes a capacity-by-voltage device, according to an embodiment. The system further includes a display in communication with the controller in various embodiments. The display is adapted to provide a depiction of battery longevity in units of time remaining in the life of the implantable medical device battery, according to various embodiments. Other aspects and embodiments are provided herein.
摘要翻译：本公开的一个方面涉及用于可植入医疗装置中的动态电池管理的系统。该系统的实施例包括用于测量可植入医疗装置电池的电池容量的两个或更多个装置。该实施例还包括连接到测量装置的控制器。控制器适于使用加权平均值来组合来自测量装置的测量值，以确定消耗的电池容量。根据各种实施例，测量装置中的至少一个包括电量计。根据实施例，至少一个测量装置包括逐个电容装置。该系统还包括在各种实施例中与控制器通信的显示器。根据各种实施例，该显示器适于以可植入医疗装置电池的寿命中剩余的时间单位提供电池寿命的描绘。本文提供了其它方面和实施例。

20. 发明申请

US20110160803A1 IMPLANTABLE DEVICE WITH BIAS FOR MRI 有权
标题翻译：具有用于MRI的偏移的可植入装置
公开(公告)号：US20110160803A1
公开(公告)日：2011-06-30
申请号：US12976862
申请日：2010-12-22
申请人： Nicholas J. Stessman , Michael J. Lyden , Thomas M. Bocek , William J. Linder , Joseph M. Bocek
发明人： Nicholas J. Stessman , Michael J. Lyden , Thomas M. Bocek , William J. Linder , Joseph M. Bocek
IPC分类号： A61N1/36
CPC分类号： A61N1/08 , A61N1/086 , A61N1/37 , A61N1/3718
摘要： An ambulatory or implantable device, such as a pacer, defibrillator, or other cardiac rhythm management device, can tolerate magnetic resonance imaging (MRI) or other noise without turning on an integrated circuit diode by selectively providing a bias voltage that can overcome an expected induced voltage resulting from the MRI or other noise.
摘要翻译：诸如起搏器，除颤器或其他心律管理装置的移动或可植入装置可以容忍磁共振成像（MRI）或其他噪声，而不通过选择性地提供可以克服预期诱导的偏置电压而导通集成电路二极管由MRI或其他噪音引起的电压。

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