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11. 发明授权

US5925038A Expandable-collapsible electrode structures for capacitive coupling to tissue 失效
标题翻译：用于电容耦合到组织的可膨胀 - 可折叠电极结构
公开(公告)号：US5925038A
公开(公告)日：1999-07-20
申请号：US628928
申请日：1996-04-08
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B17/00 , A61B17/22 , A61B18/14 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61N1/06 , A61B17/39
CPC分类号： A61N1/06 , A61B18/1492 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

12. 发明授权

US5911739A Structures for supporting diagnostic or therapeutic elements in internal body regions 失效
标题翻译：用于支持内部身体区域的诊断或治疗元件的结构
公开(公告)号：US5911739A
公开(公告)日：1999-06-15
申请号：US738856
申请日：1996-10-28
申请人： Thomas F. Kordis , James G. Whayne , Dorin Panescu , David K. Swanson , Sidney D. Fleischman
发明人： Thomas F. Kordis , James G. Whayne , Dorin Panescu , David K. Swanson , Sidney D. Fleischman
IPC分类号： A61N1/00 , A61B17/36
CPC分类号： A61B5/0422 , A61B18/1492 , A61B5/6852 , A61B5/6858 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/00839 , A61B2018/1407 , A61B2018/1435 , A61B2018/1465 , A61B2562/0209 , A61B2562/043
摘要： Elongated spline members are threaded through a hub to form depending spline legs. In one embodiment, the spline members are threaded through a puncturable material on the hub. In another embodiment, the spline members are threaded through a slotted hub, which is then encapsulated by a sealing, elastomeric material. In another embodiment, multiple spline members are looped and woven together beyond a distal end of the hub, and the distal end of the hub serves to exert a force that maintains the woven relationship of the spline members. The spline legs, which radiate from the hub, preferable carry one or more diagnostic or therapeutic elements, such as electrodes. Preferably, a base constrains the terminal ends of the spline legs in a normally expanded geometry between the hub and base.
摘要翻译：细长的花键构件穿过轮毂以形成悬垂的花键腿。在一个实施例中，花键构件穿过轮毂上的可刺破材料。在另一个实施例中，花键构件穿过开槽的毂，然后由密封的弹性体材料包封。在另一个实施例中，多个花键构件环绕并且一起超越轮毂的远端编织，轮毂的远端用于施加维持花键构件的编织关系的力。从轮毂辐射的花键腿优选携带一个或多个诊断或治疗元件，例如电极。优选地，基座以轮毂和底座之间的正常展开的几何形状约束花键腿的末端。

13. 发明授权

US5846238A Expandable-collapsible electrode structures with distal end steering or manipulation 失效
标题翻译：具有远端转向或操纵的可膨胀 - 可折叠电极结构
公开(公告)号：US5846238A
公开(公告)日：1998-12-08
申请号：US628980
申请日：1996-04-08
申请人： Jerome Jackson , James G. Whayne , Patrick M. Owens , Thomas F. Kordis , Russell B. Thompson , Dorin Panescu , David K. Swanson
发明人： Jerome Jackson , James G. Whayne , Patrick M. Owens , Thomas F. Kordis , Russell B. Thompson , Dorin Panescu , David K. Swanson
IPC分类号： A61B17/00 , A61B17/22 , A61B18/14 , A61N1/05 , A61B17/39 , A61B5/04
CPC分类号： A61B18/1492 , A61N1/056 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839
摘要： Collapsible electrode assemblies and associated methods employing a structure having an axis and a distal end. The structure comprises a wall peripherally enclosing an interior. The structure is adapted to selectively assume an expanded geometry having a first maximum diameter about the axis and a collapsed geometry having a second maximum diameter about the axis less than the first maximum diameter. An electrically conductive material is carried by the wall, forming an electrode region adapted to conform to both the normally expanded geometry and the collapsed geometry of the structure. In one implementation, a flexing element in the interior of the structure bends within the interior along the axis of the structure to displace the distal end relative to the axis. In another implementation, a stilette element within the interior of the structure imparts axial force upon the distal end along the axis of the structure, thereby axially elongating or shortening the structure.
摘要翻译：可折叠电极组件和使用具有轴线和远端的结构的相关方法。该结构包括外围围绕内部的壁。该结构适于选择性地假设具有围绕该轴线的第一最大直径的膨胀几何形状，以及具有围绕小于第一最大直径的轴线的第二最大直径的折叠几何形状。导电材料由壁承载，形成适于符合正常膨胀的几何形状和结构的折叠几何形状的电极区域。在一个实施方式中，结构内部的弯曲元件沿着结构的轴线在内部弯曲，以使远端相对于轴线移位。在另一个实施方案中，结构内部的ile tte元件沿着结构的轴线向远端施加轴向力，从而轴向地延伸或缩短结构。

14. 发明授权

US5840076A Tissue heating and ablation systems and methods using electrode structures with distally oriented porous regions 失效
标题翻译：组织加热和消融系统和使用具有远端取向多孔区域的电极结构的方法
公开(公告)号：US5840076A
公开(公告)日：1998-11-24
申请号：US631356
申请日：1996-04-12
申请人： David K. Swanson , Dorin Panescu , James G. Whayne , Russell B. Thompson , Patrick M. Owens
发明人： David K. Swanson , Dorin Panescu , James G. Whayne , Russell B. Thompson , Patrick M. Owens
IPC分类号： A61L29/08 , A61B17/39
CPC分类号： A61L29/085 , A61B2018/00267 , A61B2018/00839
摘要： Systems and methods for heating or ablating body tissue use a porous electrode structure in which the porous section of the structure occupies more of the distal region of the structure than the proximal region. In a preferred embodiment, at least 1/3rd of the proximal region of the structure is free of pores. The porous section can be either ultraporous or microporous.
摘要翻译：用于加热或消融身体组织的系统和方法使用多孔电极结构，其中结构的多孔部分占据比近端区域更远的结构的远侧区域。在优选的实施方案中，结构的近侧区域的至少+ E，fra 1/3 + EE rd没有孔。多孔部分可以是超蒸发的或微孔的。

15. 发明授权

US5830213A Systems for heating and ablating tissue using multifunctional electrode structures 失效
标题翻译：使用多功能电极结构加热和消融组织的系统
公开(公告)号：US5830213A
公开(公告)日：1998-11-03
申请号：US634334
申请日：1996-04-12
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Russell B. Thompson , Patrick M. Owens
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Russell B. Thompson , Patrick M. Owens
IPC分类号： A61B5/042 , A61B18/14 , A61B17/39 , A61B5/04 , A61N1/05
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00065 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00351 , A61B2018/00761 , A61B2018/00791 , A61B2018/00839 , A61B2018/00886 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2018/1472 , A61B2090/3966 , A61B2218/002 , A61B5/0422
摘要： Systems and methiods for heating or ablating tissue use a multifunctional electrode assembly. The electrode assembly includes a wall comprising an electrically conductive material peripherally surrounding an interior area. The wall has an interior surface facing the interior area and an oppositely facing exterior surface. A first element operatively associated with the exterior surface of the wall is adapted to carry out a first predetermined electrical transmitting or sensing function affecting body tissue. A second element operatively associated with the interior surface of the wall is adapted to carry out, independent of the first element, a second predetermined electrical transmitting or sensing function affecting body tissue different than the first predetermined electrical function.
摘要翻译：用于加热或消融组织的系统和方法使用多功能电极组件。电极组件包括围绕内部区域的包括导电材料的壁。壁具有面向内部区域的内表面和相对的外表面。可操作地与壁的外表面相关联的第一元件适于执行影响身体组织的第一预定的电传递或感测功能。与壁的内表面可操作地相关联的第二元件适于独立于第一元件执行影响不同于第一预定电功能的身体组织的第二预定电传输或感测功能。

16. 发明授权

US5711305A Systems and methods for acquiring endocardially or epicardially paced electrocardiograms 失效
标题翻译：获得心内膜或心外膜心电图的系统和方法
公开(公告)号：US5711305A
公开(公告)日：1998-01-27
申请号：US393158
申请日：1995-02-17
申请人： David K. Swanson , James G. Whayne , Dorin Panescu
发明人： David K. Swanson , James G. Whayne , Dorin Panescu
IPC分类号： A61B1/005 , A61B5/042 , A61B5/0452 , A61B18/14 , A61N1/05 , G06F17/00 , G06F19/00 , A61B5/0402 , A61N1/36
CPC分类号： G06F19/3406 , A61B5/0422 , A61B5/04525 , A61B5/6855 , A61B5/6858 , A61N1/056 , G06F19/3487 , A61B1/0051 , A61B18/1492
摘要： Systems and methods acquire electrocardiograms using a first electrode associated with a region of heart tissue and a second body surface electrode. An analog or digital processing element is coupled to the first and second electrodes for conditioning the first electrode to emit a pacing signal and for conditioning the second electrode to sense paced electrocardiograms occurring as a result of the pacing signal. The systems and methods also employ a template of an electrocardiogram of a cardiac event of known diagnosis; for example an arrhythmia that the physician seeks to treat. This event-specific template comprises a plot of biopotentials over time and not a spacial distribution of endocardial surface activation. The systems and methods compare this event-specific template to a sample of a paced electrocardiogram. The paced electrocardiogram sample comprises a plot of biopotentials over time and not a spacial distribution of endocardial surface activation. The comparison yields a matching coefficient indicating how alike the input sample is to the input template. The matching coefficient can be used by the physician, for example, to aid in the location of sites that are potentially appropriate for ablation.
摘要翻译：系统和方法使用与心脏组织区域和第二体表电极相关联的第一电极获取心电图。模拟或数字处理元件耦合到第一和第二电极，用于调节第一电极以发出起搏信号并调节第二电极以感测由于起搏信号而产生的起搏心电图。系统和方法还采用已知诊断的心脏事件的心电图的模板; 例如医师寻求治疗的心律失常。该事件特定模板包括随时间的生物电势图，而不是心内膜表面活化的空间分布。系统和方法将此事件特定的模板与起搏心电图的样本进行比较。起搏心电图样本包括随时间的生物电势图，而不是心内膜表面活化的空间分布。比较产生一个表示输入样本与输入模板相似的匹配系数。例如，医生可以使用匹配系数来帮助可能适合于消融的部位的位置。

17. 发明授权

US06788969B2 Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions 有权
标题翻译：用于控制在内部身体区域使用诊断或治疗仪器的交互式系统和方法
公开(公告)号：US06788969B2
公开(公告)日：2004-09-07
申请号：US10267715
申请日：2002-10-10
申请人： Daniel A. Dupree , Tuan Nguyen , Dorin Panescu , James G. Whayne , David McGee , David K. Swanson
发明人： Daniel A. Dupree , Tuan Nguyen , Dorin Panescu , James G. Whayne , David McGee , David K. Swanson
IPC分类号： A61B50402
CPC分类号： A61B5/0422 , A61B5/0464 , A61B5/06 , A61B5/063 , A61B5/6858 , A61B5/7435 , A61B5/7445 , A61B5/7475 , A61B18/1492 , A61B2018/00214 , A61B2018/00898 , G06F19/00 , G06F19/3481 , G16H10/60 , G16H40/63
摘要： An interface is associated with a structure which, in use, is deployed in an interior body region of a patient. The structure includes an operative element coupled to a controller, which establishes an operating condition for the operative element to perform a diagnostic or therapeutic procedure in the interior body region. The interface generates a first display comprising an image of the structure at least partially while the operative element performs the procedure. The interface also generates a second display comprising one or more data fields reflecting the operating condition of the controller. The interface enables selection of the first display or the second display for viewing on a display screen.
摘要翻译：界面与在使用中部署在患者的内部身体区域中的结构相关联。该结构包括耦合到控制器的操作元件，其建立操作元件在内部身体区域中执行诊断或治疗过程的操作条件。该接口在操作元件执行该过程时至少部分地生成包括该结构的图像的第一显示器。接口还产生包括反映控制器的操作条件的一个或多个数据字段的第二显示器。该接口使得能够选择第一显示器或第二显示器以在显示屏幕上观看。

18. 发明授权

US06565511B2 Systems for recording use of structures deployed in association with heart tissue 有权
公开(公告)号：US06565511B2
公开(公告)日：2003-05-20
申请号：US10114779
申请日：2002-04-02
申请人： Dorin Panescu , David K. Swanson , David F. Dueiri , David McGee , Daniel A. Dupree , James G. Whayne , Robert R. Burnside , Tuan Nguyen
发明人： Dorin Panescu , David K. Swanson , David F. Dueiri , David McGee , Daniel A. Dupree , James G. Whayne , Robert R. Burnside , Tuan Nguyen
IPC分类号： A61B800
CPC分类号： A61B5/6858 , A61B5/0422 , A61B5/06 , A61B5/065 , A61B5/7435 , A61B2562/0209 , A61B2562/043 , A61B2562/08 , G06F19/00
摘要： A system records use of a structure deployed in operative association with heart tissue in a patient. An image controller generates an image of the structure while in use in the patient. An input receives data including information identifying the patient. An output processes the image in association with the data as a patient-specific, data base record for storage, retrieval, or manipulation.

19. 发明授权

US06490468B2 Systems for recording use of structures deployed in association with heart tissue 有权
公开(公告)号：US06490468B2
公开(公告)日：2002-12-03
申请号：US09804880
申请日：2001-03-12
申请人： Dorin Panescu , David K. Swanson , David F. Dueiri , David McGee , Daniel A. Dupree , James G. Whayne , Robert R. Burnside , Tuan Nguyen
发明人： Dorin Panescu , David K. Swanson , David F. Dueiri , David McGee , Daniel A. Dupree , James G. Whayne , Robert R. Burnside , Tuan Nguyen
IPC分类号： A61B505
CPC分类号： A61B5/6858 , A61B5/0422 , A61B5/06 , A61B5/065 , A61B5/7435 , A61B2562/0209 , A61B2562/043 , A61B2562/08 , G06F19/00
摘要： A system records use of a structure deployed in operative association with heart tissue in a patient. An image controller generates an image of the structure while in use in the patient. An input receives data including information identifying the patient. An output processes the image in association with the data as a patient-specific, data base record for storage, retrieval, or manipulation.

20. 发明授权

US06216043B1 Asymmetric multiple electrode support structures 失效
标题翻译：不对称多电极支撑结构
公开(公告)号：US06216043B1
公开(公告)日：2001-04-10
申请号：US08742569
申请日：1996-10-28
申请人： David K. Swanson , James G. Whayne , Thomas F. Kordis , Dorin Panescu
发明人： David K. Swanson , James G. Whayne , Thomas F. Kordis , Dorin Panescu
IPC分类号： A61N100
CPC分类号： A61B5/0422 , A61N1/056 , A61N1/0565 , A61N1/06 , A61N1/20 , A61N1/403
摘要： Multiple electrode support structures have asymmetric geometries, either axially, or radially, or both. The asymmetric support structures are assembled from spline elements that extend between a distal hub and a proximal base. In one embodiment, the spline elements are circumferentially spaced about the distal hub in a radially asymmetric fashion, creating a greater density of spline elements in one region of the structure than in another region. In the same or another embodiment, the spline elements are preformed in an axially asymmetric fashion along their lengths, creating a different geometry in their distal regions than in their proximal regions.
摘要翻译：多个电极支撑结构具有轴向或径向或两者的不对称几何形状。不对称支撑结构由在远端轮毂和近侧基座之间延伸的花键元件组装。在一个实施例中，花键元件以径向不对称的方式围绕远侧轮毂周向间隔开，在结构的一个区域中产生比在另一个区域更大的花键元件密度。在相同或另一个实施例中，花键元件沿它们的长度以轴向不对称的方式预成型，在它们的远侧区域中产生与其近端区域不同的几何形状。

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