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11. 发明公开

EP1893081A2 IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 审中-公开
标题翻译：植入无线传感器在体内压力测量
公开(公告)号：EP1893081A2
公开(公告)日：2008-03-05
申请号：EP06785286.3
申请日：2006-06-21
申请人： CardioMems, Inc.
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , CROS, Florent , KROH, Jason , STERN, David , ALLEN, Mark
IPC分类号： A61B5/00 , A61B5/07 , A61B5/0215
CPC分类号： A61B5/0031 , A61B5/0215 , A61B5/076 , A61B2560/0219 , A61B2562/028
摘要： A sensor suitable for in vivo implantation has a capacitive circuit and a three-dimensional inductor coil connected to the capacitive circuit to form an LC circuit. The LC circuit is hermetically encapsulated within an electrically insulating housing. An electrical characteristic of the LC circuit is responsive to a change in an environmental parameter.

12. 发明公开

EP1677852A2 IMPLANTABLE WIRELESS SENSOR 审中-公开
标题翻译：植入无线传感器
公开(公告)号：EP1677852A2
公开(公告)日：2006-07-12
申请号：EP04788841.7
申请日：2004-09-16
申请人： CARDIOMEMS, INC.
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , KROH, Jason , ALLEN, Mark , STERN, David
IPC分类号： A61M1/00
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/076 , Y10T29/49016 , Y10T29/49069 , Y10T29/49071 , Y10T29/49073
摘要： The progress of a endovascular aneurysm repair can be monitored by inserting a pressure transducer sensor using a catheter into the sac during endovascular aneurysm repair and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. In one aspect a sensor is introduced into the body by the steps of loading the sensor into a catheter, and deploying into the aneurysm sac. This invention also has other applications for measuring physical properties in patients or in other sites.

13. 发明申请

WO2011100009A1 METHOD AND SYSTEM FOR CREATING HISTORY-MATCHED SIMULATION MODELS 审中-公开
标题翻译：用于创建历史匹配模拟模型的方法和系统
公开(公告)号：WO2011100009A1
公开(公告)日：2011-08-18
申请号：PCT/US2010/056725
申请日：2010-11-15
申请人： EXXONMOBIL UPSTREAM RESEARCH COMPANY , STERN, David , OYERINDE, Adedayo, S. , SAHNI, Isha , SUBRAMANIAN, Ganesan
发明人： STERN, David , OYERINDE, Adedayo, S. , SAHNI, Isha , SUBRAMANIAN, Ganesan
IPC分类号： G06G7/48
CPC分类号： G01V11/00 , E21B43/00 , E21B43/16 , E21B47/00 , G01V1/282 , G01V99/005 , G01V2210/66 , G01V2210/663 , G05B13/024 , G06F17/18 , G06F17/50 , G06F17/5009 , G06F2217/16 , G06Q10/063
摘要： A method for matching production history to flow simulations includes identifying a plurality of parameters that control an objective function measuring the mismatch between a flow simulation response in a parameter subspace and a production history. A value is calculated for an objective function and for a static measurement at each of a plurality of experiments in the parameter subspace. These results are used to develop a mathematical relationship between one or more static measurements and the objective function. During subsequent adjustment of the simulation model, a target window in the objective function is identified, and flow simulations are performed for each modified model that is predicted from the static geologic measurement to produce an objective function within the window. An objective function of each flow simulation to the production history is calculated and the procedure is iterated until the objective function is within a target range.
摘要翻译：用于将生产历史与流程模拟相匹配的方法包括识别控制参数子空间中的流动模拟响应与生产历史之间的不匹配的目标函数的多个参数。在参数子空间中的多个实验的每一个处，针对目标函数和静态测量计算一个值。这些结果用于开发一个或多个静态测量与目标函数之间的数学关系。在仿真模型的后续调整过程中，识别目标函数中的目标窗口，并对从静态地质测量预测的每个修改后的模型进行流模拟，以在窗口内产生目标函数。计算每个流程仿真到生产历史的目标函数，并重复该过程，直到目标函数在目标范围内。

14. 发明申请

WO2005042032A1 METHODS FOR TREATING MULTIPLE SCLEROSIS 审中-公开
标题翻译：治疗多发性硬化症的方法
公开(公告)号：WO2005042032A1
公开(公告)日：2005-05-12
申请号：PCT/US2004/036170
申请日：2004-10-28
申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , YAN, Shi, Du , STERN, David
发明人： YAN, Shi, Du , STERN, David
IPC分类号： A61K48/00
CPC分类号： A61K31/00 , A61K38/1774
摘要： This invention provides a method for treating a subject afflicted with multiple sclerosis comprising administering to the subject a therapeutically effective amount of soluble receptor for advanced glycation endproducts (sRAGE). This invention further provides a method for inhibiting CD4 + T-cell migration comprising contacting the CD4 + T-cell with soluble receptor for advanced glycation endproducts (sRAGE). This invention further provides a method for inhibiting chemokine receptor activation in a subject comprising administering to the subject a therapeutically effective amount of soluble receptor for advanced glycation endproducts (sRAGE). Finally, this invention provides related articles of manufacture.
摘要翻译：本发明提供了治疗患有多发性硬化症的受试者的方法，其包括向受试者施用治疗有效量的晚期糖基化终产物（sRAGE）的可溶性受体。本发明进一步提供了一种抑制CD4 + T细胞迁移的方法，包括使CD4 + T细胞与晚期糖基化终产物（sRAGE）的可溶性受体接触。本发明进一步提供了一种用于抑制受试者中趋化因子受体活化的方法，其包括向受试者施用治疗有效量的晚期糖基化终产物（sRAGE）的可溶性受体。最后，本发明提供了相关的制造品。

15. 发明申请

WO1995002209A1 ATHLETIC SHOE WITH TIMING DEVICE 审中-公开
标题翻译：具有定时装置的ATHLETIC SHOE
公开(公告)号：WO1995002209A1
公开(公告)日：1995-01-19
申请号：PCT/US1994007293
申请日：1994-07-01
申请人： THOMPSON, James , STERN, David
发明人： THOMPSON, James , STERN, David , CHERDAK, Erik, B.
IPC分类号： G04B47/00
CPC分类号： A43B23/24 , A43B3/00 , A43B3/0005 , A43B3/0078 , G04B47/00
摘要： An athletic shoe (1100) which includes a timing device (4105) for measuring the amount of time the athletic shoe is off the ground and in the air. The athletic shoe can also include a notification device (4115) which can be operatively coupled to the timing device (4105) for notifying a wearer of the athletic shoe of a message. The message can include information related to the amount of time the athletic shoe is off the ground and in the air.
摘要翻译：一种运动鞋（1100），其包括用于测量运动鞋离开地面和空中的时间量的计时装置（4105）。运动鞋还可以包括通知装置（4115），该通知装置可操作地联接到定时装置（4105），用于通知消费者运动鞋的佩戴者。该消息可以包括与运动鞋离开地面和空中的时间量有关的信息。

16. 发明申请

WO2021119201A1 METHODS AND SYSTEMS FOR THREE-DIMENSIONAL LIGHTSHEET IMAGING 审中-公开
公开(公告)号：WO2021119201A1
公开(公告)日：2021-06-17
申请号：PCT/US2020/064117
申请日：2020-12-09
申请人： ENUMERIX, INC. , LAI, Janice , STERN, David
发明人： LAI, Janice , STERN, David
IPC分类号： G02B27/09
摘要： Disclosed herein are light sheet imaging systems for imaging fluorescent samples. Also disclosed herein are sample holder systems for high throughput light sheet imaging of multiple three-dimensional samples without user intervention. Further disclosed herein are automated image processing methods to identify and quantify fluorescent particles within three-dimensional image sets without user intervention or user bias.

17. 发明申请

WO2013009774A1 METHOD AND APPARATUS FOR CUSTOMIZED PROVISIONING OF ON-LINE APPLICATION CHANNELS 审中-公开
标题翻译：定制提供在线应用通道的方法和装置
公开(公告)号：WO2013009774A1
公开(公告)日：2013-01-17
申请号：PCT/US2012/046107
申请日：2012-07-10
申请人： ROKU, INCORPORATED , WOOD, Anthony , STERN, David , WESTERHOFF, David , ATARAS, Bill , GOODWIN, Mark , GRAHAM, Aaron , EMERSON, Matt , PHILLIPS, Kevin
发明人： WOOD, Anthony , STERN, David , WESTERHOFF, David , ATARAS, Bill , GOODWIN, Mark , GRAHAM, Aaron , EMERSON, Matt , PHILLIPS, Kevin
IPC分类号： H04M1/24 , H04M3/08 , H04M3/22
CPC分类号： H04L65/4069 , H04L65/1063 , H04L65/4076
摘要： A method for a computer system includes receiving an identifier associated with a client streaming player, determining one or more attributes associated with the identifier from a data structure in response to the identifier, determining available channels from a plurality of channels that are to be made available to the client streaming player in response to the identifier, wherein available channels comprises a first channel, but not the second channel, determining a first graphical identifier associated with the first channel, providing the first graphical identifier to the client streaming player, receiving a user selection of the first graphical identifier indicating a user request to associate the first channel with the computer system, and providing an indicator of a server network address associated with the first channel to the client streaming player.
摘要翻译：一种用于计算机系统的方法包括：接收与客户端流播放器相关联的标识符，响应于所述标识符从数据结构确定与所述标识符相关联的一个或多个属性，从多个信道中确定可用信道响应于所述标识符到所述客户端流播放器，其中可用信道包括第一信道而不是所述第二信道，确定与所述第一信道相关联的第一图形标识符，向所述客户端流播放器提供所述第一图形标识符，接收用户选择第一图形标识符，指示用户请求将第一频道与计算机系统相关联，以及向客户端流播放器提供与第一频道相关联的服务器网络地址的指示符。

18. 发明申请

WO2006035233A1 METHOD FOR PERFORMING RETAIL SALES ANALYSIS 审中-公开
标题翻译：执行零售销售分析的方法
公开(公告)号：WO2006035233A1
公开(公告)日：2006-04-06
申请号：PCT/GB2005/003746
申请日：2005-09-30
申请人： DUNNHUMBY LIMITED , SPRINGFIELD, Paul , BLAKE, Edwin , STERN, David
发明人： SPRINGFIELD, Paul , BLAKE, Edwin , STERN, David
IPC分类号： G06Q30/00
CPC分类号： G06Q30/02 , G06Q30/0201
摘要： The invention provides a user with substantial flexibility in requesting and generating analysis projects on transaction and/or consumer data that is stored in one or more databases. Exemplary embodiments of the invention provide a method for retailers and other authorized users, such as suppliers, to access and perform sophisticated, highly specialized analysis on transaction and/or consumer data, such as retail sales and consumer data, from a remote location using an internet connected computer. The transaction and/or consumer data that is accessed can be a compilation of retail transaction data (collected from EPOS systems, for example) and/or consumer data (which has been collected from frequent-shopper or loyalty cards used by consumers when they shop, for example). Projects are generated as spreadsheet based interactive reports, which are easy to manipulate for further analysis and presentations. Insights from these projects can lead to better decisions on new product launches, sampling, merchandizing, assortment, distribution, and other sales and marketing priorities. Exemplary projects may be interactive, allowing the user to manipulate and extract information which is specific to the user's particular needs.
摘要翻译：本发明为用户提供了在存储在一个或多个数据库中的关于事务和/或消费者数据的请求和生成分析项目方面的巨大灵活性。本发明的示例性实施例提供了一种用于零售商和其他授权用户（例如供应商）从远程位置访问和执行关于交易和/或消费者数据（例如零售销售和消费者数据）的复杂，高度专门化的分析的方法，其使用互联网连接电脑。访问的交易和/或消费者数据可以是零售交易数据（例如从EPOS系统收集）和/或消费者数据的汇编（其已经被消费者在购物时使用的频繁购物者或会员卡中收集，例如）。项目生成为基于电子表格的交互式报告，易于操作以进行进一步的分析和演示。这些项目的见解可以为新产品推出，抽样，商品化，分类，分销以及其他销售和营销优先事项做出更好的决策。示例性项目可以是交互式的，允许用户操纵和提取特定于用户特定需求的信息。

19. 发明申请

WO2004095221A3 APPARATUS AND METHODS FOR ANALYZING AND CHARACTERIZING NUCLEIC ACID SEQUENCES 审中-公开
公开(公告)号：WO2004095221A3
公开(公告)日：2004-11-04
申请号：PCT/US2004/006693
申请日：2004-03-04
申请人： PERLEGEN SCIENCES, INC. , PATIL, Nila , BERNO, Anthony, J. , KONVICKA, Karel , HINDS, David, A. , SHEN, Naiping , STERN, David , SHEEHAN, John, B.
发明人： BERNO, Anthony, J. , KONVICKA, Karel , HINDS, David, A. , SHEN, Naiping , STERN, David , SHEEHAN, John, B.
IPC分类号： G01N33/48
摘要： Computer-implemented methods, data processing apparatus and computer program codes for characterizing an interrogation position, such as a SNP position, in a nucleic acid sequence are provided herein. Computer-implemented methods involving various statistical analyses are provided for characterizing an interrogation position as being associated with a phenotypic trait of interest.

20. 发明公开

EP1545303A2 IMPLANTABLE WIRELESS SENSOR FOR BLOOD PRESSURE MEASUREMENT WITHIN AN ARTERY 审中-公开
标题翻译：植入无线传感器的血压在动脉
公开(公告)号：EP1545303A2
公开(公告)日：2005-06-29
申请号：EP03785007.0
申请日：2003-08-07
申请人： CARDIOMEMS, INC.
发明人： ALLEN, Mark , FONSECA, Michael , WHITE, Jason , KROH, Jason , STERN, David
IPC分类号： A61B5/02 , A61B5/04 , A61B6/00
CPC分类号： A61B5/0215 , A61B5/6882
摘要： Intra-arterial blood pressure is monitored by inserting a pressure transducer sensor (250) using a catheter (258) into an artery and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. In one aspect a sensor (250) is introduced into the body by the steps of folding or rolling the sensor into a cylinder, loading it into a catheter, and deploying into the artery by allowing it to unroll or unfold, either by itself or facilitated by the incorporation of a super-elastic allow component.

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