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1. 发明公开

EP1893081A2 IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 审中-公开
标题翻译：植入无线传感器在体内压力测量
公开(公告)号：EP1893081A2
公开(公告)日：2008-03-05
申请号：EP06785286.3
申请日：2006-06-21
申请人： CardioMems, Inc.
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , CROS, Florent , KROH, Jason , STERN, David , ALLEN, Mark
IPC分类号： A61B5/00 , A61B5/07 , A61B5/0215
CPC分类号： A61B5/0031 , A61B5/0215 , A61B5/076 , A61B2560/0219 , A61B2562/028
摘要： A sensor suitable for in vivo implantation has a capacitive circuit and a three-dimensional inductor coil connected to the capacitive circuit to form an LC circuit. The LC circuit is hermetically encapsulated within an electrically insulating housing. An electrical characteristic of the LC circuit is responsive to a change in an environmental parameter.

2. 发明公开

EP1893080A2 METHOD OF MANUFACTURING IMPLANTABLE WIRELESS SENSOR FOR IN VIVO PRESSURE MEASUREMENT 审中-公开
标题翻译：方法用于生产可植入无线传感器在体内压力测量
公开(公告)号：EP1893080A2
公开(公告)日：2008-03-05
申请号：EP06785262.4
申请日：2006-06-21
申请人： CardioMems, Inc.
发明人： O'BRIEN, David , ABERCROMBIE, Matthew , FONSECA, Michael , CROS, Florent , PARK, Jin Woo , SINGH, Angad
IPC分类号： A61B5/00
CPC分类号： A61B5/0215 , A61B5/02055 , A61B5/6882 , A61B2562/0247 , A61B2562/12 , A61N1/36564 , H05K3/32 , Y10T29/49117 , Y10T29/4913
摘要： A method of manufacturing a sensor for in vivo applications includes the steps of providing two wafers of an electrically insulating material. A recess is formed in the first wafer, and a capacitor plate is formed in the recess of the first wafer. A second capacitor plate is formed in a corresponding region of the second wafer, and the two wafers are affixed to one another such that the first and second capacitor plates are arranged in parallel, spaced-apart relation.

3. 发明公开

EP1677852A2 IMPLANTABLE WIRELESS SENSOR 审中-公开
标题翻译：植入无线传感器
公开(公告)号：EP1677852A2
公开(公告)日：2006-07-12
申请号：EP04788841.7
申请日：2004-09-16
申请人： CARDIOMEMS, INC.
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , KROH, Jason , ALLEN, Mark , STERN, David
IPC分类号： A61M1/00
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/076 , Y10T29/49016 , Y10T29/49069 , Y10T29/49071 , Y10T29/49073
摘要： The progress of a endovascular aneurysm repair can be monitored by inserting a pressure transducer sensor using a catheter into the sac during endovascular aneurysm repair and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. In one aspect a sensor is introduced into the body by the steps of loading the sensor into a catheter, and deploying into the aneurysm sac. This invention also has other applications for measuring physical properties in patients or in other sites.

4. 发明公开

EP2021757A2 HERMETIC CHAMBER WITH ELECTRICAL FEEDTHROUGHS 有权
标题翻译：电气成就密闭腔
公开(公告)号：EP2021757A2
公开(公告)日：2009-02-11
申请号：EP07867119.5
申请日：2007-05-15
申请人： CardioMems, Inc.
发明人： O'BRIEN, David , COURCIMAULT, Christophe , YOU, Liang
IPC分类号： G01L9/12
CPC分类号： G01L9/0042 , G01L9/0075
摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

5. 发明公开

EP1871224A2 ELECTROMAGNETICALLY COUPLED HERMETIC CHAMBER 审中-公开
标题翻译：电磁耦合气密腔
公开(公告)号：EP1871224A2
公开(公告)日：2008-01-02
申请号：EP06740891.4
申请日：2006-04-12
申请人： CardioMems, Inc.
发明人： ALLEN, Mark , O'BRIEN, David
IPC分类号： A61B5/0215
CPC分类号： A61B5/021 , A61B5/03
摘要： An electromagnetically coupled hermetic chamber includes a body defining a hermetic chamber. A first conductive structure is disposed within the hermetic chamber, and a second conductive structure is attached to the body outside of the hermetic chamber. The first conductive structure is electromagnetically coupled to the second conductive structure without direct electrical paths connecting the first and second conductive structures. Thus the first conductive structure can be coupled to external electronics without the need for electrical feedthroughs or vias that could compromise the integrity of the hermetic chamber.

6. 发明申请

WO2008066569A2 HERMETIC CHAMBER WITH ELECTRICAL FEEDTHROUGHS 审中-公开
标题翻译：带电子馈线的密封室
公开(公告)号：WO2008066569A2
公开(公告)日：2008-06-05
申请号：PCT/US2007/011612
申请日：2007-05-15
申请人： CARDIOMEMS, INC. , O'BRIEN, David , COURCIMAULT, Christophe , YOU, Liang
发明人： O'BRIEN, David , COURCIMAULT, Christophe , YOU, Liang
IPC分类号： G01L9/12
CPC分类号： G01L9/0042 , G01L9/0075
摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.
摘要翻译：压力腔是耐用的，稳定的和生物相容性的，并且以这样的方式配置，使得它构成微微至纳升级的体积。压力腔与外部环境密封，同时保持与其他设备通信的能力。微机械密封传感器配置为通过与外部电子设备的直接电接触来接收电源并返回信息。设置在其中的压力腔和传感器部件与环境气密密封以减少传感器内的漂移和不稳定性。该传感器设计用于恶劣和生物环境，例如体内植入和体内使用。此外，采用新颖的制造方法构建传感器。

7. 发明申请

WO2007061841A2 CAPACITOR ELECTRODE FORMED ON SURFACE OF INTEGRATED CIRCUIT CHIP 审中-公开
标题翻译：集成电路芯片表面形成电容器电极
公开(公告)号：WO2007061841A2
公开(公告)日：2007-05-31
申请号：PCT/US2006/044670
申请日：2006-11-17
申请人： CARDIOMEMS, INC. , O'BRIEN, David , YOU, Liang
发明人： O'BRIEN, David , YOU, Liang
IPC分类号： G01L9/12
CPC分类号： G01L9/0075
摘要： A sensor has a sensor housing defining a cavity therein. A first wall partially defining the cavity is deflectable under a physiologically relevant range of pressures. An integrated circuit chip bearing electronics is fixedly mounted within the cavity. A capacitor comprises first and second capacitor plates in generally parallel, spaced-apart relation. The first capacitor plate is physically coupled to the deflectable wall so as to move as the wall deflects, and the second capacitor plate is carried by the chip. The second capacitor plate is in electrical communication with the input pad of the chip.
摘要翻译：传感器具有在其中限定空腔的传感器外壳。部分地限定空腔的第一壁在生理学上相关的压力范围内是可偏转的。集成电路芯片轴承电子器件固定地安装在腔内。电容器包括大致平行且间隔开的关系的第一和第二电容器板。第一电容器板物理耦合到可偏转壁，以便当壁偏转时移动，并且第二电容器板由芯片承载。第二电容器板与芯片的输入焊盘电连通。

8. 发明授权

EP2021757B1 HERMETIC CHAMBER WITH ELECTRICAL FEEDTHROUGHS 有权
标题翻译：电气成就密闭腔
公开(公告)号：EP2021757B1
公开(公告)日：2011-04-06
申请号：EP07867119.5
申请日：2007-05-15
申请人： CardioMems, Inc.
发明人： O'BRIEN, David , COURCIMAULT, Christophe , YOU, Liang
IPC分类号： G01L9/12
CPC分类号： G01L9/0042 , G01L9/0075
摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

9. 发明申请

WO2007047794A2 HERMETIC CHAMBER WITH ELECTRICAL FEEDTHROUGHS 审中-公开
标题翻译：具有电子充电器的电磁室
公开(公告)号：WO2007047794A2
公开(公告)日：2007-04-26
申请号：PCT/US2006/040777
申请日：2006-10-19
申请人： CARDIOMEMS, INC. , O'BRIEN, David , COURCIMAULT, Christophe , YOU, Liang , JOUNG, Yeun-Ho , ALLEN, Mark
发明人： O'BRIEN, David , COURCIMAULT, Christophe , YOU, Liang , JOUNG, Yeun-Ho , ALLEN, Mark
IPC分类号： G01L9/00
CPC分类号： G01L9/0073
摘要： An exemplary pressure cavity is disclosed that is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The exemplary pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from ambient pressure in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g., intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.
摘要翻译：公开了一种示例性的压力腔，其是耐用的，稳定的和生物相容的并且以这样的方式配置，使得其构成微微至纳升级体积。示例性压力腔与外部环境气密密封，同时保持与其他装置通信的能力。微加工的密封传感器配置为通过与外部电子设备的直接电气接触来接收电力和返回信息。设置在其中的压力腔和传感器部件与环境压力密封，以减少传感器内的漂移和不稳定性。传感器设计用于恶劣和生物环境，例如体内植入和体内使用。另外，采用新颖的制造方法来构造传感器。

10. 发明申请

WO2005027998A2 IMPLANTABLE WIRELESS SENSOR 审中-公开
标题翻译：可植入无线传感器
公开(公告)号：WO2005027998A2
公开(公告)日：2005-03-31
申请号：PCT/US2004/030727
申请日：2004-09-16
申请人： CARDIOMEMS, INC. , O'BRIEN, David , WHITE, Jason , FONSECA, Michael , KROH, Jason , ALLEN, Mark , STERN, David
发明人： O'BRIEN, David , WHITE, Jason , FONSECA, Michael , KROH, Jason , ALLEN, Mark , STERN, David
IPC分类号： A61M
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/076 , Y10T29/49016 , Y10T29/49069 , Y10T29/49071 , Y10T29/49073
摘要： The progress of a endovascular aneurysm repair can be monitored by inserting a pressure transducer sensor using a catheter into the sac during endovascular aneurysm repair and then using a small, hand-held read out device to measure pressure easily, safely, inexpensively and accurately. In one aspect a sensor is introduced into the body by the steps of loading the sensor into a catheter, and deploying into the aneurysm sac. This invention also has other applications for measuring physical properties in patients or in other sites.
摘要翻译：血管内动脉瘤修复的进展可以通过在血管内动脉瘤修复期间使用导管插入囊中的压力传感器传感器来监测，然后使用小的手持式读出装置来容易，安全，低成本且准确地测量压力。在一个方面，通过将传感器加载到导管中并且部署到动脉瘤囊中的步骤将传感器引入体内。本发明还具有用于测量患者或其他部位物理性质的其它应用。

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