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11. 发明申请

WO1995017920A1 SLIP-LAYERED CATHETER BALLOON 审中-公开
公开(公告)号：WO1995017920A1
公开(公告)日：1995-07-06
申请号：PCT/US1994014199
申请日：1994-12-09
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , WANG, James, C. , CHIN, Yem
IPC分类号： A61M29/00
CPC分类号： A61M25/1029 , A61M25/0045 , A61M25/1034 , A61M25/1038 , A61M25/104 , A61M2025/1075
摘要： A slip-layered balloon catheter (10) for insertion into a bodily conduit, especially an artery. The catheter comprises a shaft (21) having at least one lumen (26) for delivery of a fluid inflation media and a slip-layered balloon (12, 30a) made up of a plurality of layers (14, 15, 37) with a low-friction substance (18, 42) between the layers. The low-friction substance causes the layers to slide readily relative to one another, softening the balloon while maintaining its strength. Optionally, the balloon (30a) includes a plurality of slip-layered segments (40) radially disposed about the balloon wall, and separated by lengthwise ridges (41) joining the layers of each segment together. Also optionally, an elastic sleeve (51) surrounds the balloon wall to improve refordability of the balloon (50).
摘要翻译：一种用于插入身体导管，特别是动脉的滑层气囊导管（10）。导管包括具有用于输送流体膨胀介质的至少一个腔（26）和由多个层（14,15,37）构成的滑动分层球囊（12,30a）的轴（21）层之间的低摩擦物质（18,42）。低摩擦物质使得层彼此相对滑动，同时保持其强度而软化球囊。可选地，球囊（30a）包括围绕气球壁径向设置的多个滑动分层段（40），并且通过将每个段的层连接在一起的纵向脊（41）分开。还可选地，弹性套筒（51）围绕球囊壁以改善球囊（50）的反向性。

12. 发明申请

WO1995009667A1 MEDICAL DEVICE BALLOONS CONTAINING THERMOPLASTIC ELASTOMERS 审中-公开
标题翻译：含有热塑性弹性体的医疗器械气囊
公开(公告)号：WO1995009667A1
公开(公告)日：1995-04-13
申请号：PCT/US1994010961
申请日：1994-09-28
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , HAMILTON, Bruce , SAHATJIAN, Ronald, A.
IPC分类号： A61M29/00
CPC分类号： A61M25/1029 , A61L29/049 , A61L29/12 , A61M25/0045 , A61M25/1002 , A61M25/1038 , A61M2025/1075 , C08L67/02 , C08L71/02
摘要： A dilatation balloon and catheter for insertion into a bodily conduit. The catheter (10) includes shaft (12) and a dilatation balloon (24) at the distal end of the shaft. The balloon is inflated via a central lumen (14) in the shaft for delivery of a fluid inflation media. The balloon is fabricated from a combination of a thermoplastic elastomer (TPE), preferably an engineering thermoplastic elastomer (ETE), with a non-compliant structural polymeric material. The combination may be a blend of the non-compliant structural polymer and the TPE. Alternatively, the combination may be a layered balloon having, for example, a non-compliant structural polymer inner layer and a soft, abrasion resistant, elastomeric outer layer. Methods for fabricating the balloon from the combination of a TPE and a non-compliant structural polymer are also disclosed.
摘要翻译：用于插入身体导管的扩张球囊和导管。导管（10）在轴的远端包括轴（12）和膨胀气球（24）。气球通过轴中的中心腔（14）膨胀，用于输送流体充气介质。气球由热塑性弹性体（TPE），优选工程热塑性弹性体（ETE）与非柔顺结构聚合材料的组合制成。该组合可以是不顺应结构聚合物和TPE的混合物。或者，组合可以是具有例如不顺应结构聚合物内层和柔软，耐磨损的弹性体外层的分层气囊。还公开了从TPE和不顺应结构聚合物的组合制造球囊的方法。

13. 发明申请

WO1995005574A2 ZEBRA EXCHANGE GUIDE WIRE 审中-公开
标题翻译： ZEBRA EXCHANGE指导线
公开(公告)号：WO1995005574A2
公开(公告)日：1995-02-23
申请号：PCT/US1994009347
申请日：1994-08-15
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , ROWLAND, Christopher, A. , BARDSLEY, Earl , DeMELLO, Richard
IPC分类号： F61C03/14
CPC分类号： A61M25/09 , A61B90/39 , A61B2090/3937 , A61M2025/0008 , A61M2025/09083 , A61M2025/09091 , A61M2025/09166 , A61M2025/09175 , A61M2025/1093
摘要： An exchange guide wire (10) for positioning and exchanging medical catheters within a bodily passage during a medical procedure which uses an endoscope. The guide wire includes a wire (32) of a length sufficient for exchange of the catheters through the endoscope, a radiopaque flexible coil (38) fixed to the distal end (22) of the wire, and a pattern of stripes (26) endoscopically discernable along the guide wire. A low-friction sleeve (18), for example of a shrink wrap material, jackets the guide wire, the stripes being endoscopically discernable along the length of the jacketed guide wire. The position of the exchange guide wire stripes relative to the endoscope optical lens may be monitored by viewing the stripes endoscopically. A method of positioning and exchanging medical catheters within a bodily passage during a medical procedure which uses an endoscope is also disclosed. The method utilizes one of the above-described exchange guide wires (10), and involves: positioning the exchange guide wire distal tip (22) within the bodily passage; fluoroscopically confirming the position of the exchange guide wire; threading one of the catheters onto the guide wire to position this catheter within the bodily passage; exchanging catheters by withdrawing the one catheter from the bodily passage over the exchange guide wire, threading the other catheter onto the exchange guide wire to position it within the bodily passage; and endoscopically monitoring movement of the stripes (26) relative to the endoscope optical lens during the exchange and preventing withdrawal of the exchange guide wire during the exchange.
摘要翻译：一种用于在使用内窥镜的医疗过程中在身体通道内定位和交换医疗导管的交换引导线（10）。引导线包括足够长度以用于通过内窥镜交换导管的导线（32），固定到线的远端（22）的不透射线的柔性线圈（38）和内窥镜的条纹（26）沿着导丝识别。诸如收缩包裹材料的低摩擦套筒（18）夹住导丝，条带沿着夹套的导丝的长度被内窥镜识别。交替引导线相对于内窥镜光学透镜的条纹的位置可以通过内镜观察来监视。还公开了在使用内窥镜的医疗过程中在身体通道内定位和交换医疗导管的方法。该方法使用上述交换导丝（10）之一，并且包括：将换向导丝远端（22）定位在身体通道内; 透视确认交换导丝的位置; 将导管之一穿过引导线，以将该导管定位在身体通道内; 通过将一个导管从身体通道上取出交换引导线来交换导管，将另一导管穿过交换导丝以将其定位在身体通道内; 并且在交换期间内窥镜监视条（26）相对于内窥镜光学透镜的移动，并且防止在交换期间退出交换导丝。

14. 发明申请

WO1995005129A1 MEDICAL DEVICE WITH IMPROVED ACTUATING HANDLE 审中-公开
标题翻译：具有改进动作手柄的医疗装置
公开(公告)号：WO1995005129A1
公开(公告)日：1995-02-23
申请号：PCT/US1994009346
申请日：1994-08-15
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , KLINE, Craig, R.
IPC分类号： A61B19/00
CPC分类号： A61M25/0136 , A61B17/221 , A61B17/2909 , A61B17/32056 , A61B18/24 , A61B2017/00849 , A61B2017/00853 , A61B2017/22038 , A61B2017/22051 , A61B2017/2212 , A61B2017/2215 , A61B2017/2912 , A61B2017/292 , A61B2017/301 , A61B2018/1407 , A61M25/0133 , A61M25/0147 , A61M25/10 , A61M2025/015
摘要： This invention is a medical device (10) having a body (18), an actuating member (24) mounted to move relative to the body, a working element (20) and an elongated force transmitting member (12) capable of transmitting force between the actuating member and the working element. The force transmitting member includes a flexible cable portion. The force transmitting member is attached on one side of the cable portion to the body, and associated in a driving relationship on an opposite side of the cable portion with the working element. The actuating member includes a pulley surface (26) bodily movable therewith. The cable portion is trained about the pulley surface such that movement of the actuating member, given a distance relative to the body, causes the working element to move a substantially greater distance than the given distance.
摘要翻译：本发明是一种医疗装置（10），其具有主体（18），安装成相对于主体移动的致动构件（24），工作元件（20）和细长力传递构件（12），其能够在致动构件和工作元件。力传递构件包括柔性电缆部分。力传递部件在电缆部分的一侧附接到主体，并且在电缆部分的与工作元件相对的一侧上以驱动关系相关联。致动构件包括能够与其一体移动的滑轮表面（26）。电缆部分围绕滑轮表面进行训练，使致动构件相对于主体给定一定距离的运动导致工作元件移动比给定距离大得多的距离。

15. 发明申请

WO1995000198A1 DILATION CATHETER AND METHOD OF TREATMENT THEREWITH 审中-公开
标题翻译：放电导管及其处理方法
公开(公告)号：WO1995000198A1
公开(公告)日：1995-01-05
申请号：PCT/US1994007180
申请日：1994-06-24
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , ABELE, John, E. , NICHOLAS, Peter, M. , WANG, James, C.
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1011 , A61M2025/1072 , A61M2025/1075 , A61M2025/1086
摘要： A catheter for insertion into a bodily conduit, especially an artery. The catheter comprises a shaft (26) having at least one lumen (24) for delivery of a fluid inflation media and a double balloon (12) including an array (20) of a plurality of inflatable secondary chambers (22) radially disposed in a cylindrical array around an inflatable primary chamber (16). Each of the secondary chambers (22) shares a common wall (38) with adjacent secondary chambers (22) and a common wall (14) with the primary chamber (16). The secondary chambers (22) are inflated by an array of channels (32) which are separated from each other by webs (40). One or more of the secondary chambers (22) may be in communication with a pressure transducer for measurement of the resistance of, e.g., a stenosis to dilation by the balloon (12). Alternately, a triple balloon (60) has inner secondary chambers (22a) and outer secondary chambers (22b). Also alternately, one or more of the secondary chambers (22) may be adapted to dispense medication. A method for treating a constricted bodily conduit using the catheter is also disclosed.
摘要翻译：用于插入身体导管，特别是动脉的导管。导管包括具有用于输送流体膨胀介质的至少一个内腔（24）的轴（26）和包括放射状设置在多个可膨胀的第二腔室（22）中的多个可充气副腔室（22）的阵列（20）的双气囊（12）围绕可充气主室（16）的圆柱形阵列。每个次级室（22）与相邻的副室（22）和与主室（16）的公共壁（14）共用公共壁（38）。二次室（22）由通过腹板（40）彼此分离的通道阵列（32）而膨胀。二次腔室（22）中的一个或多个可以与压力传感器连通，用于测量例如由球囊（12）扩张的狭窄的阻力。或者，三重气囊（60）具有内部辅助腔室（22a）和外侧副腔室（22b）。还可以选择地，一个或多个第二腔室（22）可适于分配药物。还公开了一种使用导管治疗收缩的身体导管的方法。

16. 发明申请

WO1994023786A1 PROSTHESIS DELIVERY SYSTEM 审中-公开
标题翻译： PROSTHESIS交付系统
公开(公告)号：WO1994023786A1
公开(公告)日：1994-10-27
申请号：PCT/US1994003959
申请日：1994-04-12
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , ROBERTS, George, T. , WILSON, Darin , ANDERSEN, Erik , STROHBAND, Hans-Peter
IPC分类号： A61M29/00
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9517
摘要： This invention provides prosthesis delivery systems (2) with a traumatic tip (26) that can be dislodged from the catheter (4) so that the catheter (4) can be easily removed from the body after expanding the prosthesis (14), by pulling the catheter (4) proximally. With the tip (26) dislodged, the catheter (4), which is of smaller diameter than the tip (26) can be removed even in instances where the prosthesis (14) does not expand the lumen to a large diameter. This invention also provides prosthesis delivery systems (2) with a contoured protective outer sheath (20) having smaller diameters in proximal portions that normally are acutely bent when the system is in the body, than in distal portions corresponding to the position of the prosthesis (14). These systems are more flexible and the sheaths (20) less likely to kink, especially when configured as part of a large delivery system.
摘要翻译：本发明提供了具有可以从导管（4）移出的创伤性尖端（26）的假体递送系统（2），使得在扩张假体（14）之后可以容易地从体内移除导管（4），通过拉动近端导管（4）。在尖端（26）移开时，甚至在假体（14）不将内腔膨胀到大直径的情况下也可以去除直径小于尖端（26）的导管（4）。本发明还提供了具有轮廓保护外护套（20）的假体输送系统（2），其在近端部分具有较小的直径，当系统在体内时通常会急剧弯曲，而不是对应于假体位置的远端部分 14）。这些系统更灵活，并且护套（20）不太可能扭结，特别是当配置为大型输送系统的一部分时。

17. 发明申请

WO1994023669A1 PROSTHESIS DELIVERY SYSTEM WITH DILATING TIP 审中-公开
标题翻译： PROSTHESIS交付系统与DILATING提示
公开(公告)号：WO1994023669A1
公开(公告)日：1994-10-27
申请号：PCT/US1994003942
申请日：1994-04-11
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , ROBERTS, George, T. , ANDERSEN, Erik
IPC分类号： A61F02/06
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/044
摘要： This invention provides prosthesis delivery systems (2) with tips (26) constructed to permit both easier advance into the body and easier removal from the body after expanding the prosthesis (14). The tip (26) includes a distal taper (28) that can gently widen a lumen during advance in instances where the lumen is narrower than the tip (26) and a proximal taper (29) that can gently widen the lumen on retraction in instances where the prosthesis (14) does not immediately expand the lumen to provide clearance for the larger diameter tip (26).
摘要翻译：本发明提供了假体输送系统（2），其具有构造成允许在扩张假体（14）之后容易地进入身体并且更容易地从身体移除的尖端（26）。尖端（26）包括远端锥体（28），远端锥体（28）可以在腔内比尖端（26）更窄的情况下预先轻轻地加宽内腔，而近端锥体（29）可以在收缩时轻轻加宽内腔其中假体（14）不立即膨胀管腔以为较大直径尖端（26）提供间隙。

18. 发明申请

WO1994022384A1 ELECTRO-COAGULATION AND ABLATION AND OTHER ELECTROTHERAPEUTIC TREATMENTS OF BODY TISSUE 审中-公开
标题翻译：身体组织的电凝和消融及其他电疗法
公开(公告)号：WO1994022384A1
公开(公告)日：1994-10-13
申请号：PCT/US1994003379
申请日：1994-03-29
申请人： BOSTON SCIENTIFIC CORPORATION , ABELE, John, E. , ROWE, Steven , ROWLAND, Christopher, A. , VERGANO, Michael, G.
发明人： BOSTON SCIENTIFIC CORPORATION
IPC分类号： A61B17/39
CPC分类号： A61B18/1477 , A61B17/00234 , A61B18/1402 , A61B18/1492 , A61B2017/00292 , A61B2018/00196 , A61B2018/00595 , A61B2018/1425 , A61M3/0279 , A61M2025/0079 , A61M2025/0089
摘要： A catheter includes a flexible elongated catheter body (10), a retractable needle or probe (36), and an electrode (26) mounted on the distal portion of the catheter body (10). The needle (36) provides a fluid passage (39) for introducing fluid (e.g., sclerotic agents for enhancing electrocoagulation of the tissue, heat responsive drugs for improving bonding to tissue surfaces, or vasoconstrictor drugs) into tissue. The electrode (26) can provide bipolar electrocoagulation by means of two separate constituent electrodes, or alternatively, the electrode (26) can be employed in combination with either the needle or probe (36) to establish the bipolar elecrocoagulation path through tissue into which the needle or probe (36) extends. The electrode (26), in combination with the needle or probe (36), may also be used to provide a mapping function inside cardiac chambers.
摘要翻译：导管包括柔性细长导管主体（10），可缩回针或探针（36）以及安装在导管主体（10）的远端部分上的电极（26）。针（36）提供用于将流体（例如，用于增强组织的电凝的硬化剂，用于改善与组织表面的粘合的热反应性药物或血管收缩剂药物）引入组织的流体通道（39）。电极（26）可以通过两个单独的组成电极提供双极电凝，或者，电极（26）可以与针或探针（36）组合使用以建立通过组织的双极电凝途径，其中针或探针（36）延伸。与针或探针（36）组合的电极（26）也可用于在心室内提供映射功能。

19. 发明申请

WO1994007446A1 DEVICE AND METHOD FOR HEATING TISSUE 审中-公开
标题翻译：用于加热组织的装置和方法
公开(公告)号：WO1994007446A1
公开(公告)日：1994-04-14
申请号：PCT/US1993009422
申请日：1993-10-04
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , FRAM, Daniel, Bruce , BERNS, Ellison , ROPIAK, Susan, M. , ROWE, Donald, Steven
IPC分类号： A61F07/12
CPC分类号： A61B18/082 , A61B2017/00039 , A61B2017/00084 , A61B2017/00973 , A61B2017/22062 , A61B2018/046 , A61B2090/3933 , A61M25/104
摘要： A balloon catheter (34) is provided that includes a catheter shaft (10) constructed for insertion into a blood vessel, a balloon (8) mounted on the catheter shaft, and a heating device (26) located within the balloon and arranged for heating fluid inside the balloon to permit heating of tissue by thermal conduction from the fluid to the tissue through a wall of the balloon. The balloon catheter (34) is inserted into a blood vessel and the balloon (8) is passed through the right atrium of the heart and into the coronary sinus of the heart. The balloon (8) is inflated with the fluid, and the fluid is heated inside the balloon (8) through use of the heating device (26) to cause heat to pass from the fluid to surrounding tissue by thermal conduction through the wall of the balloon (8).
摘要翻译：提供了一种气囊导管（34），其包括构造成用于插入血管的导管轴（10），安装在导管轴上的气囊（8）和位于球囊内的加热装置（26）球囊内的流体，以允许通过从气体通过气球的壁从流体到组织的热传导来加热组织。气球导管（34）插入血管中，气囊（8）通过心脏的右心房并进入心脏的冠状窦。气囊（8）用流体充气，并且通过使用加热装置（26）将气体加热到气囊（8）内，以通过热传导通过壁的热导致热量从流体传递到周围组织气球（8）。

20. 发明申请

WO1994003230A1 SUPPORT CATHETER ASSEMBLY 审中-公开
标题翻译：支持导管总成
公开(公告)号：WO1994003230A1
公开(公告)日：1994-02-17
申请号：PCT/US1993007337
申请日：1993-08-04
申请人： BOSTON SCIENTIFIC CORPORATION
发明人： BOSTON SCIENTIFIC CORPORATION , KONTOS, Stavros, B.
IPC分类号： A61M29/00
CPC分类号： A61F2/95 , A61B90/39 , A61F2/88 , A61F2250/0098 , A61M25/104
摘要： A support catheter assembly (10) for facilitating medical procedures includes a tubular body and a continuous lumen from its proximal end to its distal end. A manipulating member is connected to the tubular body (12) for inserting, advancing, withdrawing and maneuvering the body during a medical procedure. The manipulating member may be a wire (14) of a manipulating tube (16). The tubular body also may be provided with a funnel shaped (26) lumen opening at its proximal end to facilitate insertion of devices therethrough, and radiopaque markers for subcutaneously detecting the location of the device during a medical procedure and, more particularly, for detecting its location relative to other devices used in the medical procedure. A method also is disclosed for using the tube assembly to facilitate insertion of a PTCA catheter into a stenotic region and for holding open the lumen through that region after angioplasty has been performed.
摘要翻译：用于促进医疗过程的支撑导管组件（10）包括管状主体和从其近端到其远端的连续内腔。操作构件连接到管状体（12），用于在医疗过程中插入，推进，取出和操纵身体。操纵构件可以是操纵管（16）的线（14）。管状体还可以在其近端处设置有漏斗形（26）腔开口，以便于穿过其中的装置插入，以及不透射线标记，用于在医疗过程期间皮下检测装置的位置，更具体地，用于检测其相对于医疗程序中使用的其他设备的位置。公开了一种用于使用管组件以便于将PTCA导管插入狭窄区域并且在血管成形术已经执行之后保持将该腔开放通过该区域的方法。

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