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    • 1. 发明授权
    • Method for quantitative measurement of trace enzyme and substrate used
therein
    • 其中使用的痕量酶和底物的定量测定方法
    • US5300421A
    • 1994-04-05
    • US727347
    • 1991-07-08
    • Nobuhito MasudaNobuo SuzukiShoji IshiguroMitsunori Ono
    • Nobuhito MasudaNobuo SuzukiShoji IshiguroMitsunori Ono
    • C12Q1/00G01N33/535G01N33/58G01N33/53
    • C12Q1/00G01N33/535G01N33/581
    • A synthetic substrate used for quantitative analysis of a trace enzyme. The substrate has a molecular structure (B)-(A)-(C) comprising at least one structure (A) catalytically affected by the enzyme to be analysed, at least one photographically active labelling structure (B) linked to the structure (A) and at least one specific adsorbing structure (C) linked to the structure (A). The substrate is used in a quantitative analysis of a trace enzyme, in which the structure (A) or the linkage between the structure (A) and the structure (C), or the linkage between the structure (B) and the structure (A) is cleaved by the action of the analyte enzyme. The reaction product of the enzymatic reaction is separated by allowing the same to contact with an adsorbent for the structure (C). The separated reaction product is developed photographically and then the optical density of the resultant developed silver and/or colored dye is measured.
    • 用于痕量酶定量分析的合成底物。 底物具有分子结构(B) - (A) - (C) - 包含至少一种被待分析酶催化影响的结构(A),至少一种与结构连接的照相活性标记结构(B) )和至少一种与结构(A)连接的特定吸附结构(C)。 该基质用于微量酶的定量分析,其中结构(A)或结构(A)和结构(C)之间的连接或结构(B)和结构(A)之间的连接 )被分析物酶的作用切割。 通过使酶反应的反应产物与用于结构(C)的吸附剂接触来分离。 分离出的反应产物用照相机显影,然后测量所得显影的银和/或着色染料的光密度。
    • 9. 发明授权
    • Silver halide photographic light-sensitive element
    • 卤化银照相感光元件
    • US4334010A
    • 1982-06-08
    • US284164
    • 1981-07-17
    • Hiroyuki MifuneShoji IshiguroTadao ShishidoYoshiharu FuseyaTeruaki Tsujikawa
    • Hiroyuki MifuneShoji IshiguroTadao ShishidoYoshiharu FuseyaTeruaki Tsujikawa
    • C07C13/20C07D333/22C07D335/02G03C1/34
    • G03C1/34C07D333/22
    • A silver halide photographic light-sensitive element is described comprising a support having thereon at least one silver halide emulsion layer, wherein at least one compound represented by formula (I) is incorporated in the silver halide emulsion layer or in another hydrophilic colloid layer: ##STR1## wherein X represents a hydroxy group or a group represented by ##STR2## wherein R.sup.2 and R.sup.3 (which may be the same or different) each reprsents hydrogen, an alkyl group, or an aryl group; R.sup.1 represents a sulfur-containing saturated heterocyclic group or a group represented by -A-S-B, wherein A represents an alkylene group and B represents hydrogen, an alkyl group, or an aryl group; and Z represents an atomic group forming a 5-membered or 6-membered unsubstituted or substituted carbocyclic ring.In the silver halide photographic light-sensitive element, the so-called "latent image fading" phenomenon is prevented without accompanying degradation of other photograhic properties.
    • 描述了一种卤化银照相感光元件,其包括其上具有至少一个卤化银乳剂层的载体,其中至少一种由式(I)表示的化合物引入卤化银乳剂层或另一亲水胶体层中: 图像(I)其中X表示羟基或由其表示的基团,其中R2和R3(可以相同或不同)各自代表氢,烷基或芳基; R1表示含硫的饱和杂环基或由-A-S-B表示的基团,其中A表示亚烷基,B表示氢,烷基或芳基; Z表示形成5元或6元未取代或取代的碳环的原子团。 在卤化银摄影感光元件中,防止所谓的“潜像褪色”现象,而不伴随着其它光致变色性能的降低。