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1. 发明申请

WO2017069116A1 ゼラチンまたはその化学修飾体、それを含有する水性組成物および医療用積層体、ならびに医療用積層体の製造方法および細胞シートの単離方法审中-公开
标题翻译：明胶或其化学改性产品，含有该组合物的水性组合物，医疗用层压体，医疗用层压体的制造方法以及细胞片的分离方法
公开(公告)号：WO2017069116A1
公开(公告)日：2017-04-27
申请号：PCT/JP2016/080829
申请日：2016-10-18
申请人：地方独立行政法人東京都立産業技術研究センター , 新田ゼラチン株式会社
发明人：大藪　淑美 , 柚木　俊二 , 畑山　博哉 , 井田　昌孝 , 平岡　陽介
IPC分类号： C07K14/78 , A61L15/32 , A61L27/00 , C08H1/06 , C09H3/00 , C12M3/04 , C12N5/071
CPC分类号： A61L15/32 , A61L27/00 , C07K14/78 , C08H1/06 , C09H3/00 , C12M3/04
摘要：ゼラチンまたはその化学修飾体は、高分子量成分の含有量が１０～５０質量％であり、高分子量成分の含有量から低分子量成分の含有量を差し引いた値が０質量％以上である。
摘要翻译：
明胶或化学修饰物是高分子量组分的10〜50质量％含量，由高分子量成分的含量中减去低分子量成分的含量得到的值是0 它不低于质量百分比。

2. 发明申请

WO2015002622A1 HIGH-BLOOM GRADE GELATIN MANUFACTURING PROCESS FROM POULTRY (CHICKEN, TURKEY, DUCK, GOOSE) TISSUES 审中-公开
标题翻译：从家禽（鸡，土耳其，鸭，鹅）组织中制备高品级明胶
公开(公告)号：WO2015002622A1
公开(公告)日：2015-01-08
申请号：PCT/TR2014/000179
申请日：2014-05-21
申请人： ATUK, Tan
发明人： ATUK, Tan
IPC分类号： C08H1/06 , A23J1/10 , A23J3/06 , C09H3/00 , C09H3/02 , C08L89/06 , C09D189/06 , A23L3/00 , A23J3/30 , A23B4/00 , A23B7/00 , A61F17/00 , A61F13/20 , A61F13/84
CPC分类号： C09H3/00 , A23J1/10 , A23J3/06 , A23J3/30 , C08H1/06 , C08L89/06 , C09D189/06 , C09H3/02
摘要： The invention is related to production of high-bloom grade gelatin from the poultry tissues (chicken, turkey, duck, goose). The goal of the invention is to develop an environment friendly process ensuring low operating cost to manufacture colorless, odourless, high grade gelatin (over 100 bloom) in line with islamic requirements from the poultry tissues.
摘要翻译：本发明涉及从家禽组织（鸡，火鸡，鸭，鹅）生产高起霜级明胶。本发明的目的是开发一种环境友好的工艺，以确保低的操作成本，以制造符合家禽组织的伊斯兰要求的无色，无味，高级明胶（超过100个花）。

3. 发明申请

WO03020840A9 METHODS FOR PURIFYING INSOLUBLE BONE GELATIN 审中-公开
标题翻译：净化不溶性骨髓蛋白的方法
公开(公告)号：WO03020840A9
公开(公告)日：2003-10-30
申请号：PCT/IB0203856
申请日：2002-09-06
申请人： PERTH BONE AND TISSUE BANK INC , FAN YING , ZHENG MING HAO , WOOD DAVID
发明人： FAN YING , ZHENG MING HAO , WOOD DAVID
IPC分类号： A61L27/22 , C07K14/78 , C08H1/00 , C09H3/00 , C09H7/00 , C07K1/30 , C07K14/495 , C07K14/50 , C07K14/51 , C07K14/65
CPC分类号： A61L27/3683 , A61L27/222 , A61L27/3608 , A61L2430/02 , C07K14/78 , C08H1/00 , C09H3/00 , C09H7/00
摘要： The present invention provides methods for purifying insoluble bone gelatin and uses for insoluble bone gelatin. The process for isolating insoluble bone gelatin from bone tissue includes grinding the bone tissue into bone powder; washing the bone powder with saline; demineralizing the bone tissue; contacting the bone powder with a neutral salt; and contacting the bone powder with a stabilizer. The present invention also discloses an insoluble bone gelatin including about 10 percent growth factor. Insoluble bone gelatin is useful, for example, in preparing impaction bone grafts.
摘要翻译：本发明提供了不溶骨胶的纯化方法和不溶性骨明胶的用途。从骨组织中分离不溶性骨明胶的方法包括将骨组织研磨成骨粉末; 用盐水洗骨粉; 使骨组织脱矿质; 使骨粉与中性盐接触; 并使骨粉与稳定剂接触。本发明还公开了包含约10％生长因子的不溶性骨明胶。不溶性骨明胶在例如制备冲击骨移植物中是有用的。

4. 发明申请

WO01064046A2 METHOD FOR ISOLATING SPONGE COLLAGEN AND PRODUCING NANOPARTICULATE COLLAGEN, AND THE USE THEREOF 审中-公开
标题翻译：方法海绵胶原的分离和生产的纳米胶原蛋白及其用途
公开(公告)号：WO01064046A2
公开(公告)日：2001-09-07
申请号：PCT/EP2001/002228
申请日：2001-02-28
IPC分类号： A61K9/06 , A23J1/04 , A61K8/00 , A61K8/65 , A61K8/96 , A61K9/10 , A61K35/56 , A61K38/17 , A61L15/32 , A61L27/24 , A61P17/02 , A61P19/02 , A61P29/00 , A61P43/00 , A61Q19/00 , C08H1/00 , C08L89/00 , C09H1/00 , C09H3/00 , A23J
CPC分类号： A61L27/24 , A23J1/04 , A61L15/325 , C08H1/00 , C08L89/00 , C09H1/00
摘要： The invention relates to a method for the simplified isolation in high yields of sponge collagen, especially from marine sponges, and to the production of collagen nanoparticles from collagen. The invention further relates to the use thereof for influencing cell-dependent processes in vitro and in vivo, especially when orally or topically administered to treat inflammatory, preferably cyclooxygenase-dependent diseases.
摘要翻译：本申请涉及到海绵胶原的简化分离的方法，特别是得自海绵，以高收率和生产由胶原胶原纳米颗粒，以及它们在特别是经口服或局部给药的体外和体内影响依赖的细胞的过程，使用用于治疗炎性，优选Cyclooxygenaseabhängiger疾病。

5. 发明申请

WO2019091502A1 BIOTECHNOLOGY-BASED PRODUCTION OF FOOD GELATINE FROM POULTRY BY-PRODUCTS 审中-公开
公开(公告)号：WO2019091502A1
公开(公告)日：2019-05-16
申请号：PCT/CZ2018/050054
申请日：2018-11-05
申请人： TOMAS BATA UNIVERSITY IN ZLIN
发明人： MOKREJS, Pavel , GAL, Robert , MRAZEK, Petr
IPC分类号： C09H3/00 , A23J1/10 , A23J3/06 , C08L89/06
CPC分类号： A23J1/001 , A23J1/10 , A23J3/06 , A23J3/342 , C08L89/06 , C09H3/00
摘要： The initial, gradual procedure involves rinsing slaughterhouse waste with water, freezing this feedstock (to the temperature of -2 to -5 °C at the core) and mincing it (in two stages) to obtain pieces of 3 mm or less in size. This is followed by a more intense process of separating non-collagenous proteins and pigments from said minced feedstock by washing them out with NaOH solution, removing fat by extraction with a solvent mixture of ethanol + petroleum ether and pre-treatment of the protein isolate with a proteolytic enzyme. After filtering out the protein hydrolysate and rinsing the swollen protein isolate with water the following take place: an initial stage of extracting gelatine; inactivation of proteolytic enzyme residues; separation of the gelatinous solution from the remaining, undecomposed fraction of the protein isolate by filtration; a second stage of extracting gelatine - multi-level extraction from the swollen protein isolate at a temperature that increases at each level, and the formation of gelatine from the extracted solutions; and biotechnological processing of the remaining undecomposed fraction to obtain collagen hydrolysate.

6. 发明申请

WO2015002622A4 HIGH-BLOOM GRADE GELATIN MANUFACTURING PROCESS FROM POULTRY (CHICKEN, TURKEY, DUCK, GOOSE) TISSUES 审中-公开
标题翻译：来自POULTRY（鸡，土耳其，DUCK，GOOSE）组织的高分级凝胶制造工艺
公开(公告)号：WO2015002622A4
公开(公告)日：2015-02-19
申请号：PCT/TR2014000179
申请日：2014-05-21
申请人： ATUK TAN
发明人： ATUK TAN
IPC分类号： C08H1/06 , A23B4/00 , A23B7/00 , A23J1/10 , A23J3/06 , A23J3/30 , A23L3/00 , A61F13/20 , A61F13/84 , A61F17/00 , C08L89/06 , C09D189/06 , C09H3/00 , C09H3/02
CPC分类号： C09H3/00 , A23J1/10 , A23J3/06 , A23J3/30 , C08H1/06 , C08L89/06 , C09D189/06 , C09H3/02
摘要： The invention is related to production of high-bloom grade gelatin from the poultry tissues (chicken, turkey, duck, goose). The goal of the invention is to develop an environment friendly process ensuring low operating cost to manufacture colorless, odourless, high grade gelatin (over 100 bloom) in line with islamic requirements from the poultry tissues.
摘要翻译：本发明涉及从家禽组织（鸡，火鸡，鸭，鹅）生产高华级明胶。本发明的目的是开发一种环保的方法，确保低生产成本，以制造无菌，无味，高品质的明胶（超过100升），符合家禽组织的伊斯兰教要求。

7. 发明申请

WO2006121361A1 PROCESS FOR THE PREPARATION OF GELATINE AND GELATINE HYDROLYZATE 审中-公开
标题翻译：制备GELATINE和GELATINE水解产物的方法
公开(公告)号：WO2006121361A1
公开(公告)日：2006-11-16
申请号：PCT/PL2006/000028
申请日：2006-05-10
申请人： GRABEK, Halina , GRABEK, Kazimierz
发明人： GRABEK, Halina , GRABEK, Kazimierz
IPC分类号： C09H3/00 , C09H3/02
CPC分类号： C09H3/00 , C09H3/02
摘要： The process of the invention for the preparation of the gelatine consists in that the crumbled animal bones are subjected to the maceration process with the acid of the concentration of not higher than 34% at the time from 1 to 14 days, during the maceration or after its termination from the post-maceration lyes the calcium salts are sepatated, and the ossein produced in this way, after the remainder of the acid is removed, possibly with the addition of the alkaline substance, is subjected to at least once extraction with water of the temperature from 40 to 1200°C, possibly in the case of the production of the gelatine hydrolyzate, to the water extract of the gelatine the proteolytic enzym is added and next it is inactivated, then the water extract of the gelatine or the gelatine hydrolyzate is cleaned using the known methods, the extract is concentrated, possibly dried and milled. The process of the invention is characterized in that the fat is removed from the reaction environment at the time of the maceration process and/or the extraction and/or after the termination of the maceration process and/or the extraction by the separation of the water phase containing the gelatine and the fatty phase and possibly the solid phase.
摘要翻译：用于制备明胶的本发明的方法在于，在浸渍或浸渍之后，粉碎的动物骨头在浸渍过程中，在1至14天的时间内，浓度不高于34％的酸进行浸渍处理其后浸出液终止钙盐分离，并且以这种方式产生的骨胶蛋白，除去残余的酸后，可能加入碱性物质，至少用水提取一次温度为40〜1200℃，可能在生产明胶水解液的情况下，向明胶水提取液中加入蛋白水解酶，然后将其灭活，然后将明胶或明胶水解产物的水提取物使用已知的方法进行清洁，提取物被浓缩，可能干燥并研磨。本发明的方法的特征在于，在浸渍过程和/或提取和/或在浸渍过程终止之后和/或通过分离水提取时，从反应环境中除去脂肪相包含明胶和脂肪相以及可能的固相。

8. 发明申请

WO2004046227A3 METHOD OF PRODUCING ELECTROSTATICALLY CHARGED GELATIN 审中-公开
标题翻译：生产静电带电明胶的方法
公开(公告)号：WO2004046227A3
公开(公告)日：2004-09-16
申请号：PCT/US0336281
申请日：2003-11-10
申请人： MEOW MIX COMPANY , LIN CHARLES , DAHLGREN JAY , MORRIS SCOTT , THOMPSON RICHARD
发明人： LIN CHARLES , DAHLGREN JAY , MORRIS SCOTT , THOMPSON RICHARD
IPC分类号： C09H3/00 , B01J19/08
CPC分类号： C09H3/00
摘要： Methods of forming electrostatically charged gelatin are provided. Gelatin is extracted by an acid extraction method (12) thereby produced a gelatin dispersion (14), the pH of which is adjusted to the isoelectric point of the gelatin. The pH of the gelatin dispersion (14) is then further adjusted (22) so as to cause the gelatin to assume an electrostatic charge.
摘要翻译：提供形成静电荷明胶的方法。通过酸提取法提取明胶（12），由此制得明胶分散液（14），其pH值调节至明胶的等电点。然后进一步调节明胶分散体（14）的pH（22），以使明胶呈现静电荷。

9. 发明申请

WO2002094959A1 IMPROVED ALKALINE PROCESS FOR PREPARING TYPE B FISH GELATIN 审中-公开
标题翻译：用于制备B型鱼凝胶的改进的碱处理方法
公开(公告)号：WO2002094959A1
公开(公告)日：2002-11-28
申请号：PCT/GB2002/002370
申请日：2002-05-20
申请人： CRODA INTERNATIONAL PLC , FIELD, David, Stanley
发明人： FIELD, David, Stanley
IPC分类号： C09H3/00
CPC分类号： C09H3/00
摘要： A process is described for producing, from fish collagen, a type B gelatin having a pl in the range of from 4.5 to 6.0, which process comprises: (a) treating fish skins with an alkaline medium to provide a mixture thereof having a pH of at least (12); (b) acidifying, using a mineral acid, the mixture produced in step (a) to a pH of less than (7); and (c) acid-extracting the gelatin thereby produced; and, optionally, (d) further processing the extracted gelatin produced in step (c). The gelatin prepared by or preparable by the improved process of this invention can be used in the manufacture of capsules, especially soft capsules, for food and/or pharmaceutical applications. It can also be used in the preparation of a composition for photographic applications.
摘要翻译：描述了用于从鱼胶原生产具有在4.5至6.0范围内的p的B型明胶的方法，该方法包括：（a）用碱性介质处理鱼皮以提供其pH为至少（12）; （b）使用无机酸将步骤（a）中制备的混合物酸化至小于（7）的pH; 和（c）酸提取由此产生的明胶; 和（d）进一步处理在步骤（c）中生产的提取的明胶。通过本发明的改进方法制备或可制备的明胶可用于制造用于食品和/或药物应用的胶囊，尤其是软胶囊。它也可以用于制备用于照相应用的组合物。

10. 发明申请

WO2002094958A1 IMPROVED ACID PROCESS FOR THE PREPARATION OF TYPE A FISH GELATIN 审中-公开
标题翻译：用于制备A型鱼类凝胶的改进的酸法
公开(公告)号：WO2002094958A1
公开(公告)日：2002-11-28
申请号：PCT/GB2002/002348
申请日：2002-05-20
申请人： CRODA INTERNATIONAL PLC , JONES, Roger, Trevor , FIELD, David, Stanley
发明人： JONES, Roger, Trevor , FIELD, David, Stanley
IPC分类号： C09H3/00
CPC分类号： A23J1/10 , A23J1/04 , C09H3/00
摘要： A process is described for producing gelatin from fish collagen, which process comprises: (a) treating the fish skins with a 0.1-1 % w/w solution of a base for a period long enough to allow swelling of the skins but less than 5 days; (b) acidifying with a mineral acid the mixture produced in step (a) to a pH in the range of from 1 to 6; and (c) acid-extracting the gelatin from the prepared skins; and, optionally (d) further processing the extracted gelatin produced in step (c). Also described is the use of a gelatin, prepared by or preparable by a method according to this invention, in the manufacture of capsules for food, cosmetic and/or pharmaceutical applications; particularly soft gelatin capsules.
摘要翻译：描述了用于从鱼胶原生产明胶的方法，该方法包括：（a）用0.1-1％w / w的碱溶液处理鱼皮，持续足够长的时间以允许皮肤肿胀但小于5 天; （b）用无机酸将步骤（a）中产生的混合物酸化至1至6范围内的pH; 和（c）从制备的皮肤中酸提取明胶; 和任选地（d）进一步处理在步骤（c）中生产的提取的明胶。还描述了通过本发明的方法制备或可通过本发明的方法制备的明胶在制备用于食品，化妆品和/或药物应用的胶囊中的用途; 特别是软明胶胶囊。

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