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1. 发明申请

WO2017112394A1 SENSOR FOR ELECTRODE AND PROCESSES FOR PRODUCTION 审中-公开
标题翻译：电极传感器和生产过程
公开(公告)号：WO2017112394A1
公开(公告)日：2017-06-29
申请号：PCT/US2016/064920
申请日：2016-12-05
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： DERRY, Cameron E.
IPC分类号： A61B5/0424 , H01B1/22 , A61N1/04 , B05C19/00
CPC分类号： A61B5/0424 , A61B5/04087 , A61B2562/0209 , A61B2562/125 , A61N1/0456 , A61N1/046 , A61N1/0496 , H01B1/22
摘要： An electrode sensor involves a solid conductive polymeric substrate shaped as an electrode sensor or portion of an electrode sensor having a layer of silver-coated particles distributed on and embedded into a surface of the substrate. The electrode sensor is particularly useful for ECG electrodes and utilizes less silver without unduly sacrificing performance. A process for producing the electrode sensor involves distributing a layer of silver-coated particles on a surface of a solid conductive polymeric substrate shaped as an electrode sensor or portion of an electrode sensor and thermally embedding the silver-coated particles into the surface. The process is simpler and less costly than existing processes for producing electrode sensors.
摘要翻译：电极传感器包括形状为电极传感器或电极传感器的一部分的固体导电聚合物基底，该电极传感器具有分布在基底表面上并嵌入基底表面中的银涂覆颗粒层。电极传感器对于ECG电极特别有用，并且使用更少的银而不会不当地牺牲性能。用于制造电极传感器的方法涉及在形成为电极传感器或电极传感器的一部分的固体导电聚合物基底的表面上分布涂银颗粒层，并将银涂覆颗粒热嵌入表面中。该过程比现有的电极传感器生产工艺更简单，成本更低。

2. 发明申请

WO2015047873A3 SYSTEMS AND METHODS FOR VALIDATING MONITORING DEVICE PLACEMENT AND LOCATIONS 审中-公开
标题翻译：用于验证监视设备放置和位置的系统和方法
公开(公告)号：WO2015047873A3
公开(公告)日：2015-06-04
申请号：PCT/US2014056373
申请日：2014-09-18
申请人： CYBERONICS INC
发明人： SABESAN SHIVKUMAR , CARLSON GERRARD
IPC分类号： A61B5/00 , A61B5/024 , A61B5/0424
CPC分类号： A61B5/7221 , A61B5/02438 , A61B5/0245 , A61B5/0402 , A61B5/0424 , A61B5/684 , A61B7/045
摘要： This disclosure relates to devices, systems, and methods for validating locational data for a monitoring device. The external monitoring device located on a patient may include one or more processors, one or more memory devices, one or more power devices, one or more heart rate detection devices, and one or more heart sound detection devices. Further, the method may include determining a plurality of status of an external monitoring device located on a patient via one or more processors based on obtained heart rate data and obtained heart sound data. The external monitoring device state may be generated via a validation module based on the heart rate data and the heart sound data.
摘要翻译：本公开涉及用于验证监视设备的位置数据的设备，系统和方法。位于患者身上的外部监测装置可以包括一个或多个处理器，一个或多个存储装置，一个或多个功率装置，一个或多个心率检测装置以及一个或多个心脏声音检测装置。此外，该方法可以包括基于获得的心率数据和获得的心音数据，经由一个或多个处理器确定位于患者身上的外部监测装置的多个状态。外部监测装置状态可以基于心率数据和心音数据经由验证模块生成。

3. 发明申请

WO2014100631A1 REAL-TIME FEEDBACK FOR ELECTRODE CONTACT DURING MAPPING 审中-公开
标题翻译：映射期间电极接触的实时反馈
公开(公告)号：WO2014100631A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/077019
申请日：2013-12-20
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： MASKARA, Barun , THAKUR, Pramodsingh H. , ARCOT-KRISHNAMURTHY, Shantha , SHOME, Shibaji , SAHA, Sunipa , SHUROS, Allan C. , MEYER, Scott A.
IPC分类号： A61B5/00 , A61B5/042 , A61B5/0424 , A61B5/107 , A61B18/14
CPC分类号： A61B5/0538 , A61B5/0422 , A61B5/0424 , A61B5/044 , A61B5/6858 , A61B5/6885 , A61B18/1492 , A61B2017/00044 , A61B2017/00053 , A61B2018/00267 , A61B2018/00678 , A61B2018/00839 , A61B2090/065
摘要： A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on amplitudes of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.
摘要翻译：导管系统包括包括多个映射电极的映射导管，每个映射电极被配置为感测与解剖结构相关联的信号。导管系统还包括可操作地耦合到多个映射电极并且被配置为接收由多个映射电极感测的信号的处理器，基于感测信号的幅度表征由多个映射电极感测的信号，并且生成基于信号表征，输出多个映射电极与解剖结构的接触质量。

4. 发明申请

WO2012149466A3 BODY ASSOCIATED DEVICE AND METHOD OF MAKING SAME 审中-公开
公开(公告)号：WO2012149466A3
公开(公告)日：2012-11-01
申请号：PCT/US2012/035650
申请日：2012-04-27
申请人： PROTEUS BIOMEDICAL, INC. , ARNE, Lawrence , HUTCHISON, James
发明人： ARNE, Lawrence , HUTCHISON, James
IPC分类号： A61B5/0402 , A61B5/0408 , A61B5/0424
摘要： Methods of manufacturing a body associated device are disclosed. The methods include providing an inlay substrate comprising a first side, a second side, and at least one conductive trace and providing an interposer substrate comprising a first side, a second side, and at least one conductive trace. An electrically conductive layer is applied to the first side of the inlay substrate. The at least one conductive trace is electrically coupled to the conductive layer. The first side of the interposer substrate is coupled to the first side of the inlay substrate to form a subassembly. The at least one conductive trace on the interposer substrate is electrically coupled to the at least one conductive trace on the inlay substrate through the electrically conductive layer. A body associated device with a wet electrode manufactured in accordance with a first process is disclosed. A body associated device with a dry electrode manufactured in accordance with a second process is disclosed.

5. 发明申请

WO2008135952A1 ACTIVE DISCHARGE OF ELECTRODE 审中-公开
标题翻译：主动放电电极
公开(公告)号：WO2008135952A1
公开(公告)日：2008-11-13
申请号：PCT/IB2008/051788
申请日：2008-05-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , U.S. PHILIPS CORPORATION , DOUGLAS, Alexander Ulrich
发明人： DOUGLAS, Alexander Ulrich
IPC分类号： A61B5/0424 , A61B5/0428 , G01R27/26
CPC分类号： A61B5/04284 , A61B5/0424
摘要： The disclosure is directed to a capacitive sensor for measuring a small biomedical electrical charge originating from an object under test comprising input circuit elements having an electrode for sensing the charge to provide an output signal that is a function of the charge being measured, wherein the electrode has no electrical contact with the object; amplification circuit elements (A) connected to the input circuit elements; processing circuit elements configured for receiving and processing the amplified output signal and to provide the measurement; and conditioning and monitoring circuit elements coupled to at least the input circuit elements comprising monitoring circuit elements and conditioning circuit elements; (Rl) wherein the monitoring circuit elements are configured for monitoring the amplified output signal to detect an error in a measurement that is greater than a preset value caused by charge buildup on the electrode; and wherein the conditioning circuit elements are configured to be activated for. discharging the electrode when the error in the measurement is detected by the monitoring circuit elements and the conditioning circuit elements are configured to be deactivated, when the error in the measurement is no longer detected.
摘要翻译：本发明涉及用于测量源自被测物体的小生物医学电荷的电容传感器，包括具有用于感测电荷的电极的输入电路元件，以提供作为被测量电荷的函数的输出信号，其中电极与物体没有电接触; 连接到输入电路元件的放大电路元件（A）处理电路元件，被配置为接收和处理放大的输出信号并提供测量; 以及调节和监测电路元件，其耦合到至少所述输入电路元件，包括监控电路元件和调理电路元件; （R1），其中所述监视电路元件被配置用于监视所述放大的输出信号，以检测测量中的误差大于由所述电极上的电荷积累引起的预设值; 并且其中所述调理电路元件被配置为被激活。当测量中的误差由监视电路元件检测到并且调节电路元件被配置为停止时，当不再检测到测量中的误差时，放电电极。

6. 发明申请

WO2008056309A3 ECG ELECTRODE CONTACT QUALITY MEASUREMENT SYSTEM 审中-公开
公开(公告)号：WO2008056309A3
公开(公告)日：2008-05-15
申请号：PCT/IB2007/054461
申请日：2007-11-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , HERLEIKSON, Earl
发明人： HERLEIKSON, Earl
IPC分类号： A61B5/0424 , A61B5/0428
摘要： A system and method are provided for generating output signals indicative of contact quality of a plurality of electrodes coupled to a patient. A signal generator coupled to a reference electrode injects an alternating signal into the patient. A plurality of differential amplifiers, each coupled to a respective one of the plurality of electrodes to detect an input signal from the patient, are operable to output a respective output signal in response to a respective input signal. The output signal generated by the respective differential amplifier is indicative of contact quality for the respective electrode.

7. 发明申请

WO2008056309A2 ECG ELECTRODE CONTACT QUALITY MEASUREMENT SYSTEM 审中-公开
标题翻译：心电电极接触质量测量系统
公开(公告)号：WO2008056309A2
公开(公告)日：2008-05-15
申请号：PCT/IB2007054461
申请日：2007-11-02
申请人： KONINKL PHILIPS ELECTRONICS NV , HERLEIKSON EARL
发明人： HERLEIKSON EARL
IPC分类号： A61B5/0424 , A61B5/0428
CPC分类号： A61B5/0424 , A61B5/0428 , A61B5/04282 , A61B5/6843
摘要： A system and method are provided for generating output signals indicative of contact quality of a plurality of electrodes coupled to a patient. A signal generator coupled to a reference electrode injects an alternating signal into the patient. A plurality of differential amplifiers, each coupled to a respective one of the plurality of electrodes to detect an input signal from the patient, are operable to output a respective output signal in response to a respective input signal. The output signal generated by the respective differential amplifier is indicative of contact quality for the respective electrode.
摘要翻译：提供了一种用于生成指示耦合到患者的多个电极的接触质量的输出信号的系统和方法。耦合到参考电极的信号发生器向患者注入交变信号。多个差分放大器，每个差分放大器耦合到多个电极中的相应一个以检测来自患者的输入信号，可操作用于响应于相应的输入信号而输出相应的输出信号。由相应差分放大器产生的输出信号指示相应电极的接触质量。

8. 发明申请

WO2008026969A1 IMPLANTABLE HEART STIMULATING DEVICE PROVIDED WITH MEANS FOR OBTAINING AN INDICATION OF A LEAD CONDUCTOR FRACTURE AND A MEDICAL SYSTEM COMPRISING SUCH A DEVICE 审中-公开
标题翻译：具有用于获得引导导体断裂指示的手段的可植入心脏刺激装置和包含这种装置的医疗系统
公开(公告)号：WO2008026969A1
公开(公告)日：2008-03-06
申请号：PCT/SE2006/000984
申请日：2006-08-28
申请人： ST. JUDE MEDICAL AB , SCHÜLLER, Hans , LINDGREN, Anders
发明人： SCHÜLLER, Hans , LINDGREN, Anders
IPC分类号： A61N1/362 , A61B5/0245 , A61B5/0402 , A61B5/0408 , A61B5/042 , A61B5/0424 , A61N1/36 , A61N1/39
CPC分类号： A61B5/0424 , A61B5/042 , A61B5/6885 , A61N1/365 , A61N1/37
摘要： Implantable heart stimulating device comprising ECG sensing means (4) to receive heart potential signals (2) from sensing electrodes at an electrode lead arranged in connection with a patient's heart. The ECG sensing means is provided with a programmable make- break threshold (6). The device further comprises a timing means (14) adapted to generate a make-break detection period (12), and a counting means (10), wherein the counting means is adapted to count the number of times that the amplitude of the heart potential signal exceeds the programmable make-break threshold during the make-break detection period, and when the number of times is higher than a predetermined value, the ECG obtained during the make-break detection period is stored in an ECG storage means (16).
摘要翻译：可植入的心脏刺激装置包括ECG感测装置（4），用于从与病人心脏相关联的电极引线处的感测电极接收心脏电位信号（2）。 ECG感测装置具有可编程的中断阈值（6）。所述装置还包括适于产生断线检测周期（12）的定时装置（14）和计数装置（10），其中所述计数装置适于对心脏电位幅度进行计数信号在制动中断检测周期期间超过可编程断线阈值，并且当次数高于预定值时，在断线检测周期期间获得的ECG被存储在ECG存储装置（16）中。

9. 发明申请

WO2005037099A8 A DEVICE ARRANGED FOR CARRYING OUT A BIOELECTRICAL INTERACTION WITH AN INDIVIDUAL AND A METHOD FOR ON-DEMAND LEAD-OFF DETECTION 审中-公开
标题翻译：用于实施与个体的生物相互作用的装置和用于求求导联检测的方法
公开(公告)号：WO2005037099A8
公开(公告)日：2007-03-15
申请号：PCT/IB2004052007
申请日：2004-10-07
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS INTELLECTUAL PROPERTY , REITER HARALD , MONTVAY ANDRAS , LAUTER JOSEF , SUCH OLAF , SCHMIDT RALF
发明人： REITER HARALD , MONTVAY ANDRAS , LAUTER JOSEF , SUCH OLAF , SCHMIDT RALF
IPC分类号： A61B5/0424
CPC分类号： A61B5/0424
摘要： A device to carry out a bioelectrical interaction with an individual by means of electrodes 29, 29a whereby an on-demand verification of the integrity of the electrical contact of the electrodes is implemented. The device 20 comprises a control unit 22 arranged to determine an occurrence of the predefined event related to a quality of a measured signal. In case the predetermined event is detected, the control unit 22 actuates the testing means 24. The testing means is arranged to generate the test signals, I1,12 and to apply them via a coupling circuit 23, 23a to the electrodes. In case it is desired that cumulative information about the contact integrity is obtained, is it sufficient to apply a single test signal per electrode. In case it is required to determine which of the electrodes has lost its contact, a sequence of test signals is generated by the sequencer 24b. The response signal from the electrodes 29, 29a is forwarded to the input filter 26, which is preferably also used for a normal signal analysis. The signal from the input filter 26 is directed via the input impedance 25, 25a to the input amplifier 28. The amplified response signal is forwarded to the signal processing means 30 which is arranged to analyze the response signal. Preferably, an amplitude analysis is done. The signal from the signal processing means 30 is supplied to the analog-to-digital converter (ADC) 32 after which a digital processing of the response signal is carried out by means of a further processing unit 34. In case the further processing unit 34 determines that the integrity of the contact is below the allowable level, the lead-off indicator 36 is actuated.
摘要翻译：通过电极29,29a与个体进行生物电相互作用的装置，从而实现对电极的电接触的完整性的按需验证。设备20包括控制单元22，其被布置为确定与测量信号的质量相关的预定事件的发生。在检测到预定事件的情况下，控制单元22致动测试装置24.测试装置被布置成产生测试信号I1,12并且经由耦合电路23,223将它们施加到电极。在需要获得关于接触完整性的累积信息的情况下，每个电极应用单个测试信号是否足够。在需要确定哪些电极已经失去其接触的情况下，测序信号的序列由定序器24b产生。来自电极29,29a的响应信号被转发到输入滤波器26，其优选也用于正常信号分析。来自输入滤波器26的信号经由输入阻抗25,25a被引导到输入放大器28.经放大的响应信号被转发到信号处理装置30，信号处理装置30用于分析响应信号。优选地，进行振幅分析。来自信号处理装置30的信号被提供给模数转换器（ADC）32，之后通过另外的处理单元34进行响应信号的数字处理。在另外的处理单元34 确定接触件的完整性低于容许水平，引导指示器36被致动。

10. 发明申请

WO2006067217A2 SENSOR SYSTEM AND METHOD FOR DETECTING PROBLEMS WITH MOUNTING OF SKIN MOUNTABLE MEDICAL DEVICES 审中-公开
标题翻译：用于通过安装皮肤安全医疗装置检测问题的传感器系统和方法
公开(公告)号：WO2006067217A2
公开(公告)日：2006-06-29
申请号：PCT/EP2005/057105
申请日：2005-12-22
申请人： NOVO NORDISK A/S , WILLERUP, Theresa, Rhoades , KLITGAARD, Peter, Christian , KRISTOFFERSEN, Bo , NIELSEN, Ole, Christian
发明人： WILLERUP, Theresa, Rhoades , KLITGAARD, Peter, Christian , KRISTOFFERSEN, Bo , NIELSEN, Ole, Christian
IPC分类号： A61B5/0424 , A61B5/053 , A61M5/142
CPC分类号： A61M5/14248 , A61B5/0531 , A61B5/4839 , A61B5/6833 , A61B5/6843 , A61M5/16836 , A61M2205/13 , G06F19/00
摘要： The invention relates to skin mountable medical devices adapted to ensure that the device or components thereof are properly in place with respect to the patient's body. In a specific aspect a medical device is provided comprising a mounting surface adapted for application to a skin surface of the subject, a transcutaneous device adapted to be arranged subcutaneously in a subject, and sensor means adapted to detect a property that can be indicative of a problematic condition relating to the interface of the device with the subject. The device further comprises circuitry for processing signals from the sensor means and for indicating that a predetermined condition associated with the interface of the device with the subject has been detected, and wherein the sensor means comprises first and second capacitor means.
摘要翻译：本发明涉及适合于确保其装置或组件相对于患者身体适当就位的可皮肤安装的医疗装置。在具体方面，提供了一种医疗装置，其包括适于施用于受试者的皮肤表面的安装表面，适于被布置在受试者中的经皮装置，以及适于检测能够指示与设备与主体的界面相关的问题状态。该装置还包括用于处理来自传感器装置的信号并且用于指示已经检测到与被检者的装置的接口相关联的预定条件的电路，并且其中传感器装置包括第一和第二电容器装置。

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