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1. 发明申请

WO2017083611A1 SYSTEM AND METHOD FOR IMPROVED PERFORMANCE IN NUCLEAR MEDICINE IMAGING 审中-公开
标题翻译：提高核医学成像性能的系统和方法
公开(公告)号：WO2017083611A1
公开(公告)日：2017-05-18
申请号：PCT/US2016/061478
申请日：2016-11-11
申请人： THE GENERAL HOSPITAL CORPORATION
发明人： OUYANG, Jinsong
IPC分类号： G01T1/161 , G01T1/166 , G01T1/24 , G21K1/02 , A61B6/03
CPC分类号： G21K1/025 , A61B6/032 , A61B6/037 , A61B6/06 , A61B6/4266 , A61B6/4405 , A61B6/4417 , A61B6/501 , A61B6/507 , G01T1/161 , G01T1/1641 , G01T1/1648 , G01T1/166 , G01T1/24
摘要： A collimator for a nuclear medical imaging process includes a cylinder or arc that is opaque to emissions from a subject arranged within an interior space. The system also includes a plurality of pin-hole collimators arranged about the cylinder or arc to permit emissions from the subject to reach a detector arranged at the exterior of the cylinder or arc, which divide the collimator into a plurality of segments. The cylinder or arc includes holes extending in one of in parallel or divergent to one another along each respective segment in the plurality of segments to permit emissions from the subject to reach the detector. The detector may include multiple segments, each configured to occupy part of an exit side of a pin-hole collimator. The detector may move relative to the pin-hole collimator to vary a pin-hole view of an imaging object at each detector position.
摘要翻译：用于核医学成像过程的准直器包括对布置在内部空间内的对象的发射不透明的圆柱或弧。该系统还包括多个围绕圆柱或圆弧布置的针孔准直器，以允许来自对象的发射到达布置在圆柱或弧的外部的检测器，该检测器将准直器分成多个分段。圆柱体或圆弧包括沿着多个分段中的每个相应分段彼此平行或彼此发散的孔，以允许来自对象的发射到达检测器。检测器可以包括多个分段，每个分段被配置为占据针孔准直器的一部分出口侧。检测器可以相对于针孔准直器移动以改变每个检测器位置处的成像对象的针孔视图。

2. 发明申请

WO2005006977A8 SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY SYSTEM 审中-公开
标题翻译：单光子发射计算机断层显像系统
公开(公告)号：WO2005006977A8
公开(公告)日：2005-05-12
申请号：PCT/US2004019752
申请日：2004-06-21
申请人： JUNI JACK E
发明人： JUNI JACK E
IPC分类号： A61B5/05 , G01T1/164 , G01T1/166 , G21K1/02
CPC分类号： G01T1/1644 , A61B6/037 , A61B6/5258 , G01T1/1648 , G01T1/166 , G21K1/025
摘要： Collimator assembly (630) is constructed with a plurality of alternating layers of lead and plastic supported between a lower support plate (632) and an upper support plate (634). Threaded adjusted members (636) extend through the lower plate (614) to the lower support member (632) and through the upper plate (612) to the upper support member (634). By adjusting the adjusting members (636) the position of the collimator assembly (630) may be adjusted relative to the remainder of the arc.
摘要翻译：准直器组件630构造有支撑在下支撑板632和上支撑板634之间的多个交替的铅和塑料层。螺纹调节构件636穿过下板614延伸至下支撑构件632并穿过上板612延伸至上支撑构件634。通过调整调整构件（636），可以相对于电弧的其余部分调整准直器组件（630）的位置。

3. 发明申请

WO1991006198A1 EMISSION TOMOGRAPHY CAROUSEL SYSTEM AND METHOD 审中-公开
标题翻译：排放TOMOGRAPHY CAROUSEL系统和方法
公开(公告)号：WO1991006198A1
公开(公告)日：1991-05-02
申请号：PCT/US1990006138
申请日：1990-10-23
申请人： A.T.F. CONSOLIDATED, INC.
发明人： A.T.F. CONSOLIDATED, INC. , DIGIOVANNA, Leonard, D. , PANETTA, Patrick, F.
IPC分类号： H05G01/00
CPC分类号： A61B6/0457 , A61B6/037 , A61B6/04 , G01T1/166
摘要： An emission tomography carousel system (10) and method for use with a stationary radiation detector (18) in Single Photon Emission Computer Tomography (SPECT) (20) procedures is disclosed. In a preferred embodiment the carousel includes two linear motion positioning tables (24) and one rotary motion positioning table (34) as part of a positionable mounting for moving the patient platform in three degrees of motion. A programmed computer controls (16) the motion of the carousel about a predetermined locus of points. The method includes positioning the carousel in a 'home' position, placing a patient in the carousel and manually positioning the patient platform to a desired close position with respect to a stationary radiation detector (18). The position is then recorded in the memory of a control computer and the procedure is repeated to obtain the desired number of radii of the patient's organ of interest to the detector.

4. 发明申请

WO2018023195A1 REAL-TIME MRI-PET-GUIDED RADIOTHERAPY SYSTEM WITH DOSE-DEPOSITION VERIFICATION 审中-公开
标题翻译：具有剂量沉积验证的实时MRI-PET引导放射治疗系统
公开(公告)号：WO2018023195A1
公开(公告)日：2018-02-08
申请号：PCT/CA2017/050916
申请日：2017-07-31
申请人： ALBERTA HEALTH SERVICES
发明人： FALLONE, B. Gino , MURRAY, Brad
IPC分类号： A61N5/10 , G01T1/02 , G01T1/164 , G01T1/166
CPC分类号： A61N5/107 , A61N5/10 , A61N5/1049 , A61N5/1071 , A61N2005/1052 , A61N2005/1055 , A61N2005/1087 , G01T1/02 , G01T1/1603 , G01T1/164 , G01T1/166
摘要： A radiotherapy system is configured to determine in vivo dose deposition of a radiotherapy treatment beam. The system includes the following components. A bi-planar magnetic resonance imaging (MRI) apparatus comprising a pair of spaced apart magnets. One of the magnets includes a hole proximal the centre thereof. A treatment beam source configured to generate a radiotherapy treatment beam. The treatment beam source is positioned to transmit the treatment beam through the hole in the magnet. A patient support configured to position a patient with the system so that a treatment target is proximal the treatment beam. A Positron Emission Tomography (PET) detector configured to obtain PET data of the treatment beam impacting the patient. The PET detector is positioned so that a transverse section of the patient that includes the treatment target lies between opposing portions of the PET detector.
摘要翻译：放射治疗系统被配置为确定放疗治疗束的体内剂量沉积。该系统包含以下组件。包括一对间隔开的磁体的双平面磁共振成像（MRI）设备。其中一个磁体包括靠近其中心的孔。治疗束源被配置为生成放射治疗束。治疗射束源定位成通过磁体中的孔传输治疗射束。患者支架被配置成用患者定位系统，使得治疗目标接近治疗束。正电子发射断层扫描（PET）检测器被配置为获取影响患者的治疗束的PET数据。 PET检测器被定位成使得包括治疗目标的患者的横切面位于PET检测器的相对部分之间。

5. 发明申请

WO2007054935A2 DYNAMIC SPECT CAMERA 审中-公开
标题翻译：动态影像相机
公开(公告)号：WO2007054935A2
公开(公告)日：2007-05-18
申请号：PCT/IL2006/001291
申请日：2006-11-09
申请人： SPECTRUM DYNAMICS LLC , ROUSSO, Benny , ZIV, Omer , NAGLER, Michael , BEN-HAIM, Shlomo
发明人： ROUSSO, Benny , ZIV, Omer , NAGLER, Michael , BEN-HAIM, Shlomo
IPC分类号： G01T1/161 , G01T1/166 , G01T1/29
CPC分类号： G01T1/161 , A61B6/037 , G01T1/166 , G01T1/2985
摘要： A dynamic SPECT camera is provided, comprising, a plurality of single-pixel detectors, a timing mechanism, in communication with each single-pixel detector, configured for enabling time-binning of the radioactive emissions impinging upon each single-pixel detector to time periods not greater than substantially 30 seconds, and a position-tracker, configured for providing information on the position and orientation of each detecting unit, with respect to the overall structure, substantially at all times, during the individual motion, the dynamic SPECT camera being configured for acquiring a tomographic reconstruction image of a region of interest of about 15 X 15 X 15 cubic centimeters, during an acquisition time of 30 seconds, at a spatial resolution of at least 10 X 10 X 10 cubic millimeter. The dynamic camera is configured for very short damping time, and may further acquire images in a stationary mode, with no motion. It is further configured for time binning at dynamically varying time-bin lengths,dynamically determining a spectral energy bin for each detecting unit, and employing an anatomic construction of voxels in the imaging and reconstruction.
摘要翻译：提供了一种动态SPECT相机，包括多个单像素检测器，与每个单像素检测器通信的定时机构，其被配置为使得能够将入射到每个单像素检测器上的放射性发射器的时间分级到时间段不大于大约30秒的位置跟踪器，以及位置跟踪器，被配置为基本上在所述单独运动期间总是提供关于每个检测单元的位置和方位的信息，所述动态SPECT相机被配置用于在30秒的采集时间期间以至少10×10×10立方毫米的空间分辨率获取约15×15×15立方厘米的感兴趣区域的断层重建图像。动态相机被配置为非常短的阻尼时间，并且可以在没有运动的情况下进一步以静止模式获取图像。它还被配置为在动态变化的时间段长度上进行时间分档，动态地确定每个检测单元的频谱能量仓，并且在成像和重构中采用体素的解剖构造。

6. 发明申请

WO2005067383A2 MULTI-DIMENSIONAL IMAGE RECONSTRUCTION 审中-公开
标题翻译：多维图像重建
公开(公告)号：WO2005067383A2
公开(公告)日：2005-07-28
申请号：PCT/IL2005/000048
申请日：2005-01-13
申请人： V-TARGET TECHNOLOGIES LTD. , ROUSSO, Benny , NAGLER, Michael
发明人： ROUSSO, Benny , NAGLER, Michael
IPC分类号： G01T1/161 , G01T1/166
CPC分类号： A61B6/481 , A61B6/4057 , A61B6/4258 , A61B6/486 , A61B6/5217 , A61B6/5241 , A61B90/39 , A61M5/007 , G01T1/161 , G01T1/166
摘要： Apparatus for radiation based imaging of a non-homogenous target area having distinguishable regions therein, comprises: an imaging unit configured to obtain radiation intensity data from a target region in the spatial dimensions and at least one other dimension, and an image four-dimension analysis unit analyzes the intensity data in the spatial dimension and said at least one other dimension in order to map the distinguishable regions. The system typically detects rates of change over time in signals from radiopharmaceuticals and uses the rates of change to identify the tissues. In a preferred embodiment, two or more radiopharmaceuticals are used, the results of one being used as a constraint on the other.
摘要翻译：用于其中具有可区分区域的非均匀目标区域的用于基于辐射的成像的装置包括：成像单元，被配置为从空间维度和至少一个其他维度中的目标区域获得辐射强度数据，以及图像四维分析单元分析空间维度中的强度数据和所述至少一个其他维度，以便映射可区分的区域。该系统通常检测来自放射性药物的信号随时间的变化率，并使用变化率来识别组织。在优选实施方案中，使用两种或更多种放射性药物，一种用于另一种放射性药物的结果。

7. 发明申请

WO1992022246A2 MEDICAL DIAGNOSTIC NUCLEAR CAMERA SYSTEM 审中-公开
标题翻译：医学诊断核相机系统
公开(公告)号：WO1992022246A2
公开(公告)日：1992-12-23
申请号：PCT/CA1992000222
申请日：1992-05-28
申请人： INDEPENDENT SCINTILLATION IMAGING SYSTEMS (ISIS) ...
发明人： INDEPENDENT SCINTILLATION IMAGING SYSTEMS (ISIS) ... , STARK, Iain
IPC分类号： A61B06/00
CPC分类号： G01T1/166 , A61B6/037 , A61B6/4429
摘要： The nuclear scintillation camera system has an improved positioner (10) including a drum (14) which is rotatable on a frame (13) which may be linearly moved along a track (11). The camera (17) is cantilevered to the drum (14) and is able to rotate about the axis of the cantilever which is parallel to an axis (15) of the drum (14). The frame (13) may be moved along the track (11) with the camera (17) in a given position for doing linear body scans, and with the patient positioned along the axis (15) of the drum (14), scans around the patient may be carried out for computed axial tomography (CAT). The system also provides a collimator changer stand (39) for exchange and storage of collimators (23) for use with the nuclear scintillation camera. The system according to the invention makes nuclear scintillation imaging easier to carry out.

8. 发明申请

WO2015189809A1 CALIBRATING IN SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY WITH MULTI-EMISSION ENERGIES 审中-公开
标题翻译：在单光子发射计算机图像与多发射能量之间进行校准
公开(公告)号：WO2015189809A1
公开(公告)日：2015-12-17
申请号：PCT/IB2015/054449
申请日：2015-06-12
申请人： SIEMENS MEDICAL SOLUTIONS USA, INC.
发明人： BHATTACHARYA, Manojeet
IPC分类号： G01T1/164
CPC分类号： G01T1/1647 , A61B6/582 , G01T1/1642 , G01T1/166 , G01T1/208 , G01T1/247 , G01T1/249 , G01T1/2964 , G01T1/40 , G01T7/005 , G12B13/00
摘要： For calibration (24) for quantitative SPECT, a multiple energy emission source (11) is used for calibration. The planar sensitivities and/or uniformities are determined at different emission energies based on detections from the multiple energy emission source. For estimating (32) the activity concentration, sensitivities and/or uniformities based on measures (26) at different emission energies increase accuracy. The multiple energy emission source (11) may alternatively or additionally be used to calibrate (40) a dose calibrator (15).
摘要翻译：对于用于定量SPECT的校准（24），使用多能量发射源（11）进行校准。基于来自多能量发射源的检测，在不同发射能量下确定平面灵敏度和/或均匀性。为了估计（32）基于不同发射能量下的测量（26）的活动浓度，灵敏度和/或均匀性提高了精度。多能发射源（11）可以替代地或附加地用于校准（40）剂量校准器（15）。

9. 发明申请

WO2011157045A1 一种应用适应性的正电子发射断层成像方法及装置审中-公开
公开(公告)号：WO2011157045A1
公开(公告)日：2011-12-22
申请号：PCT/CN2011/000006
申请日：2011-01-04
申请人：苏州瑞派宁科技有限公司 , 华中科技大学 , 谢庆国 , 刘晶晶
发明人：谢庆国 , 刘晶晶
IPC分类号： A61B6/02 , G01T1/161
CPC分类号： G01T1/166 , A61B6/037 , A61B6/4258 , A61B6/4275 , A61B6/488 , A61B6/508 , A61B6/5205 , A61B6/545 , A61B6/585

10. 发明申请

WO2005040635A2 T-SPECT 审中-公开
公开(公告)号：WO2005040635A2
公开(公告)日：2005-05-06
申请号：PCT/DE2004/002310
申请日：2004-10-18
申请人： FORSCHUNGSZENTRUM JÜLICH GMBH , LACKAS, Christian , SCHRAMM, Nils , ENGELAND, Uwe
发明人： LACKAS, Christian , SCHRAMM, Nils , ENGELAND, Uwe
IPC分类号： F16F1/02
CPC分类号： G01T1/166 , A61B6/037 , G01T1/1642
摘要： Die Erfindung betrifft eine Vorrichtung zur Durchführung eines tomographischen Verfahrens, insbesondere zur Durchführung einer Einzelphotonen-Tomographie, mit mindestens einem Multi-Loch-Kollimator und mindestens einem Detektor zur Erfassung von Photonen, die durch den Mutli-Loch-Kollimator hindurchtreten. Sie ist dadurch gekennzeichnet, dass sie Mittel aufweist, die eine Translationsbewegung relativ zwischen einem zu untersuchendem Objekt und dem oder den Detektoren mit einer Positioniergenauigkeit kleiner als 1 Millimeter ermöglichen. Der während der Durchführung des Verfahrens veränderte Position relativ zwischen Objekt und Detektor(en) mit einer Genauigkeit von kleiner als 1 Millimeter, insbesondere mit einer Genauigkeit kleiner als 0,1 Millimeter wird im anschliessenden Rekonstruktionsverfahren berücksichtigt. Hierzu wird ein Rekonstruktionsverfahren verwendet, gemäss dem Positions- und Winkelangaben zwischen Detektor und Objekt berücksichtigt: werden. Das Verfahren ist auf einem gängigen PC steuerbar und kann auch auf einem solchen ausgeführt werden.
摘要翻译：本发明涉及一种用于执行断层过程，特别是用于执行单光子断层摄影术，与至少一种多孔准直器和用于检测穿过辑阵孔准直仪的光子的至少一个检测器的装置。它的特征在于它包括的手段，使要被检查的对象和具有小于1毫米的定位精度的一个或多个探测器之间的相对平移运动。小于0.1毫米为单位考虑到在随后的重建过程精密物体和检测器（一个或多个）之间的方法相对位置的具有小于1毫米的精度执行期间改变的，尤其如此。为此，一重建方法被使用，认为根据检测器和物体之间的位置和角度的信息：给。该过程可以在标准PC上被控制，并且也可以在这样的材料上进行。

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