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1. 发明申请

WO2016196176A1 METHODS AND APPARATUS FOR BONE SEGMENTATION IN MAGNETIC RESONANCE IMAGES 审中-公开
标题翻译：磁共振成像中骨分离的方法和装置
公开(公告)号：WO2016196176A1
公开(公告)日：2016-12-08
申请号：PCT/US2016/034279
申请日：2016-05-26
申请人： CHILDREN'S MEDICAL CENTER CORPORATION
发明人： MULKERN, Robert, V. , JARRETT, Delma , BALASUBRAMANIAN, Mukund
IPC分类号： G01R33/48 , G01R33/56 , G01R33/561 , G01R33/50 , G01R33/565 , G06T7/00 , A61B5/055
CPC分类号： G06T7/0014 , B33Y50/00 , G01R33/4828 , G01R33/50 , G01R33/5608 , G01R33/5618 , G01R33/56527 , G06T5/50 , G06T7/11 , G06T7/136 , G06T7/194 , G06T2200/08 , G06T2207/10088 , G06T2207/20224 , G06T2207/30008
摘要： Methods and apparatus for processing magnetic resonance imaging (MRI) data to perform bone segmentation. MRI data comprising a set of gradient-echo images acquired throughout a spin echo is processed to generate a bone segmentation image. The bone segmentation image is generated based, at least in part, on at least two images in the set of gradient-echo images, wherein the at least two images include a first image corresponding to a beginning portion of the spin echo and a second image corresponding to a central portion of the spin echo.
摘要翻译：用于处理磁共振成像（MRI）数据以执行骨分割的方法和装置。包括在整个自旋回波中获取的一组梯度回波图像的MRI数据被处理以产生骨分割图像。骨分割图像至少部分地基于所述梯度 - 回波图像集合中的至少两个图像生成，其中所述至少两个图像包括对应于所述自旋回波的开始部分的第一图像和第二图像对应于自旋回波的中心部分。

2. 发明申请

WO2016170170A1 FAT CHARACTERIZATION METHOD USING MRI IMAGES ACQUIRED WITH A MULTIPLE-GRADIENT ECHO SEQUENCE 审中-公开
标题翻译：使用获得多级梯级顺序的MRI图像的FAT特征化方法
公开(公告)号：WO2016170170A1
公开(公告)日：2016-10-27
申请号：PCT/EP2016/059102
申请日：2016-04-22
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , UNIVERSITÉ PARIS DIDEROT - PARIS 7
发明人： LEPORQ, Benjamin , LAMBERT, Simon , VAN BEERS, Bernard
IPC分类号： G01R33/24 , A61B5/055 , G01R33/48 , G01R33/50 , G01R33/561
CPC分类号： A61B5/4872 , A61B5/055 , A61B5/748 , A61B2576/00 , G01R33/243 , G01R33/4828 , G01R33/50 , G01R33/5608 , G01R33/5615 , G01R33/5616 , G01R33/5618
摘要： A method for post-processing images of a region of interest in a subject, the images being acquired with a magnetic resonance imaging technique, the method for post-processing comprising at least the step of: unwrapping the phase of each image, extracting a real signal over echo time for at least one pixel of the unwrapped images, and calculating fat characterization parameters by using a fitting technique applied on a model, the model being a function which associates to a plurality of parameters each extracted real signal, the plurality of parameters comprising at least two fat characterization parameters and at least one parameter obtained by a measurement, the fitting technique being a non-linear least-square fitting technique using pseudo-random initial conditions.
摘要翻译：一种用于后处理受试者感兴趣区域的图像的方法，所述图像是用磁共振成像技术获取的，所述后处理方法至少包括以下步骤：展开每个图像的相位，提取真实的信号通过回波时间对于展开图像的至少一个像素，并且通过使用应用于模型的拟合技术来计算脂肪表征参数，所述模型是与每个提取的实际信号的多个参数相关联的函数，所述多个参数包括至少两个脂肪表征参数和通过测量获得的至少一个参数，拟合技术是使用伪随机初始条件的非线性最小二乘拟合技术。

3. 发明申请

WO2015181091A2 MR IMAGING USING MULTI-ECHO K-SPACE ACQUISITION 审中-公开
标题翻译：使用多重K空间采集成像
公开(公告)号：WO2015181091A2
公开(公告)日：2015-12-03
申请号：PCT/EP2015/061441
申请日：2015-05-22
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BECK, Gabriele Marianne , HUANG, Alan Jerry , VAN IJPEREN, Gerrit Hendrik
IPC分类号： G01R33/48
CPC分类号： G01R33/4818 , G01R33/4828 , G01R33/50 , G01R33/56 , G01R33/5615 , G01R33/5616 , G01R33/5617 , G01R33/5618 , G01R33/56509
摘要： The invention relates to a method of MR imaging of at least an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable fast MR imaging using a multi-echo imaging technique which is robust with respect to motion. The method of the invention comprises the steps of: - generating echo signals by subjecting the object (10) to an imaging sequence, - acquiring the echo signals, each echo signal being attributed to a k-space line, wherein a number of k-space lines, which are adjacently arranged in a part of k-space, are repeatedly sampled, with said number of k-space lines being sampled in a different sequential order per repetition, and - reconstructing a MR image from the acquired echo signals. Moreover, the invention relates to a MR device for carrying out this method as well as to a computer program to be run on a MR device.
摘要翻译：本发明涉及放置在MR装置（1）的检查体积中的至少一个物体（10）的MR成像方法。本发明的目的是使用相对于运动鲁棒的多回波成像技术来实现快速MR成像。本发明的方法包括以下步骤： - 通过使物体（10）经受成像序列产生回波信号， - 获取回波信号，每个回波信号归因于k-空间线，其中多个k- 相邻地布置在k空间的一部分中的空间线被重复采样，其中所述数量的k空间线以每次重复的不同顺序的顺序被采样，以及 - 从获取的回波信号重构MR图像。此外，本发明涉及用于执行该方法的MR设备以及要在MR设备上运行的计算机程序。

4. 发明申请

WO2014099463A1 SYSTEM AND METHOD FOR SENSITIVITY-ENHANCED MULTI-ECHO CHEMICAL EXCHANGE SATURATION TRANSFER (MECEST) MAGENTIC RESONANCE IMAGING 审中-公开
标题翻译：灵敏度增强型多重化学交换饱和传输（最佳）磁共振成像系统及方法
公开(公告)号：WO2014099463A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/074002
申请日：2013-12-10
申请人： THE GENERAL HOSPITAL CORPORATION , SUN, Phillip, Zhe
发明人： SUN, Phillip, Zhe
IPC分类号： A61B5/055
CPC分类号： G01R33/50 , G01R33/1284 , G01R33/465 , G01R33/4828 , G01R33/4838 , G01R33/5605 , G01R33/5618
摘要： A system and method for creating magnetic resonance images includes performing a first pulse sequence that saturates a selected labile spin species of the subject by applying a radiofrequency (RF) irradiation at a reference frequency and performing a second pulse sequence that saturates a selected labile spin species of the subject by applying an RF irradiation at a labeling frequency. A plurality of echoes having information pertaining to at least one of metabolites and metabolite byproducts is acquired to form a chemical exchange saturation transfer (CEST) medical imaging data set and the CEST medical imaging data set is reconstructed to form a CEST image of the subject including information about the at least one of metabolites and metabolite byproducts within the subject.
摘要翻译：用于产生磁共振图像的系统和方法包括：通过以参考频率施加射频（RF）照射并执行使选定的不稳定旋转物质饱和的第二脉冲序列来执行饱和所选择的受试者不稳定自旋种类的第一脉冲序列通过以标记频率施加RF照射来进行。获取具有与代谢物和代谢物副产物中的至少一种有关的信息的多个回波，以形成化学交换饱和转移（CEST）医学成像数据集，并重建CEST医学成像数据集，以形成对象的CEST图像，包括关于受试者内的代谢物和代谢物副产物中的至少一种的信息。

5. 发明申请

WO2013054643A1 磁気共鳴イメージング装置及び磁気共鳴イメージング方法审中-公开
标题翻译：磁共振成像装置和磁共振成像方法
公开(公告)号：WO2013054643A1
公开(公告)日：2013-04-18
申请号：PCT/JP2012/073722
申请日：2012-09-14
申请人：株式会社東芝 , 東芝メディカルシステムズ株式会社 , 油井正生
发明人：油井　正生
IPC分类号： A61B5/055
CPC分类号： G01R33/54 , G01R33/246 , G01R33/28 , G01R33/288 , G01R33/5605 , G01R33/5614 , G01R33/5617 , G01R33/5618 , G01R33/5673
摘要：　実施形態に係る磁気共鳴イメージング装置は、データ収集ユニット及びデータ処理ユニットを備える。データ収集ユニットは、励起パルスの印加後かつ磁気共鳴信号の読出し前において前記磁気共鳴信号に位相シフトを発生させる第１のオフレゾナンス高周波パルスを印加し、前記磁気共鳴信号の読出し後かつ次の励起パルスの印加前において前記位相シフトを補償する第２のオフレゾナンス高周波パルスを印加する撮像条件に従って前記磁気共鳴信号を収集する。データ処理ユニットは、前記磁気共鳴信号に対するデータ処理によって取得対象となる情報を取得する。
摘要翻译：根据本发明的实施例的磁共振成像装置配备有数据收集单元和数据处理单元。数据采集单元根据成像条件收集磁共振信号，在该条件下，在施加激励脉冲之后但在磁共振信号被读取之前，施加用于产生磁共振信号中的相移的第一非共振频率高频脉冲并且施加第二非共振高频脉冲以在读取磁共振信号之后但在施加下一激励脉冲之前补偿相移。数据处理单元通过处理关于磁共振信号的数据来获取要获取的信息。

6. 发明申请

WO2019145527A1 MR IMAGING USING A STACK-OF-STARS ACQUISITION WITH INTRINSIC MOTION CORRECTION 审中-公开
公开(公告)号：WO2019145527A1
公开(公告)日：2019-08-01
申请号：PCT/EP2019/051975
申请日：2019-01-28
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BECK, Gabriele, Marianne , WUELBERN, Jan, Hendrik , NAGARAJ, Suthambhara , BAKHRU, Akshay , KABUS, Sven
IPC分类号： G01R33/48 , G01R33/54 , G01R33/563 , G01R33/567 , G01R33/561
CPC分类号： G01R33/4826 , G01R33/543 , G01R33/5615 , G01R33/5616 , G01R33/5617 , G01R33/5618 , G01R33/5619 , G01R33/56325 , G01R33/5676
摘要： The invention relates to a method of MR imaging of an object (10). It is an object of the invention to enable MR imaging using the stack-of-stars or stack-of-spirals acquisition scheme providing an enhanced image quality in the presence of motion. The method of the invention comprises the steps of: - generating MR signals by subjecting the object to an imaging sequence comprising RF pulses and switched magnetic field gradients; - acquiring signal data according to a stack-of-stars or stack-of-spirals scheme, wherein the MR signals are acquired as radial or spiral k-space profiles from a number of parallel slices arranged at adjacent positions along a slice direction, wherein a central portion (20) of k-space is more densely sampled during the acquisition than peripheral portions (21) of k-space; - reconstructing an intermediate MR image (22-25) from sub-sampled signal data for each of a number of successive time intervals; - deriving motion induced displacements and/or deformations by registering the intermediate MR images (22-25) with each other; and - combining the sub-sampled signal data and reconstructing a final MR image therefrom, wherein a motion correction is applied according to the derived motion induced displacements and/or deformations. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

7. 发明申请

WO2014199879A1 磁気共鳴イメージング装置、及び、磁気共鳴イメージング方法审中-公开
标题翻译：磁共振成像装置和磁共振成像方法
公开(公告)号：WO2014199879A1
公开(公告)日：2014-12-18
申请号：PCT/JP2014/064828
申请日：2014-06-04
申请人：株式会社東芝 , 東芝メディカルシステムズ株式会社
发明人：待井　豊 , 草原　博志 , 葛西　由守
IPC分类号： A61B5/055
CPC分类号： G01R33/561 , A61B5/055 , G01R33/34 , G01R33/385 , G01R33/4818 , G01R33/5616 , G01R33/5618 , G01R33/56554 , G01R33/56572
摘要：　一実施形態のＭＲＩ装置（１０）は、第１収集部と、第２収集部と、画像再構成部（６２）とを有する。第１収集部は、読み出し方向傾斜磁場の印加の下で撮像領域の少なくとも一部を含む領域から収集されたＭＲ信号をサンプリングし、第１ｋ空間データを生成する。第２収集部は、第１収集部による収集時とは収集領域が読み出し方向にずれるように、読み出し方向傾斜磁場の印加の下で撮像領域の少なくとも一部を含む領域から収集されたＭＲ信号をサンプリングし、第２ｋ空間データを生成する。画像再構成部は、第１ｋ空間データと第２ｋ空間データとの位相差を示す位相差データ、及び、本スキャンで収集されたＭＲ信号に基づいて生成されるｋ空間データから画像データを再構成する。
摘要翻译：根据本发明的一个实施例的MRI装置（10）具有：第一采集单元; 第二采集单元; 和图像重新配置单元（62）。第一采集单元从读取方向应用梯度磁场的包括成像区域的至少一部分的区域获取的MR信号进行采样，并生成第一k空间数据。第二采集单元在读取方向上对梯度磁场的施加下从包括成像区域的至少一部分的区域获取的MR信号进行采样，使得获取区域在读取方向上相对于采集期间在读取方向上移位由第一采集单元生成第二k空间数据。图像重新配置单元从指示第一k空间数据和第二k空间数据之间的相位差的相位差数据和基于在主扫描中获取的MR信号生成的k空间数据重新配置图像数据。

8. 发明申请

WO2014160701A3 MRI WITH REPEATED K-T -SUB-SAMPLING AND ARTIFACT MINIMIZATION ALLOWING FOR FREE BREATHING ABDOMINAL MRI 审中-公开
标题翻译： MRI重复K-T -SUB采样和文字最小化允许免费呼吸ABDOMINAL MRI
公开(公告)号：WO2014160701A3
公开(公告)日：2014-11-20
申请号：PCT/US2014031711
申请日：2014-03-25
申请人： UNIV DUKE
发明人： CHEN NAN-KUEI , CHU MEI-LAN , SONG ALLEN
IPC分类号： G06T5/00 , A61B5/00
CPC分类号： G01R33/56509 , A61B5/0042 , A61B5/0044 , A61B5/055 , A61B5/7207 , A61B2576/00 , G01R33/4822 , G01R33/5611 , G01R33/5616 , G01R33/5618 , G01R33/56308
摘要： Methods of processing MRI image data to reduce or eliminate motion-related artifacts in MRI images includes: electronically repeatedly acquiring sets of 2D or 3D k-space data of a target region of a subject using at least one MRI pulse sequence; electronically applying a bootstrapping procedure to produce a large number of images from the acquired k-space data; then electronically evaluating the images produced by the bootstrapping procedure; and electronically identifying an image with a minimal motion-related artifact level from the evaluation of the images produced by the bootstrapping procedure.
摘要翻译：用于处理MRI图像数据以减少或消除MRI图像中的运动相关假象的方法包括：使用至少一个MRI脉冲序列电子地重复获取对象的目标区域的2D或3D k空间数据集; 电子地应用自举程序从所获取的k空间数据产生大量图像; 然后电子评估由自举程序产生的图像; 并且从通过自举程序产生的图像的评估以电子方式识别具有最小运动相关伪像级别的图像。

9. 发明申请

WO2008037994A1 METHOD FOR RADIOFREQUENCY MAPPING IN MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：磁共振成像中无线电映射的方法
公开(公告)号：WO2008037994A1
公开(公告)日：2008-04-03
申请号：PCT/GB2007/003665
申请日：2007-09-26
申请人： KCL ENTREPRISES LIMITED , DEONI, Sean, Casey, Louis , WILLIAMS, Steven
发明人： DEONI, Sean, Casey, Louis , WILLIAMS, Steven
IPC分类号： G01R33/50 , G01R33/58
CPC分类号： G01R33/583 , G01R33/50 , G01R33/5602 , G01R33/5613 , G01R33/5614 , G01R33/5618
摘要： A method of mapping a radio frequency magnetic field transmitted to a magnetic resonance imaging specimen. The method comprises the steps of: applying a first radio frequency pulse having a first excitation angle to the specimen and at a first time period after applying the first pulse applying one or more second radio frequency pulses each having a second excitation angle to the specimen, with a second time period between second pulses, to obtain a first data set defining a first sample of an image space; applying one or more third radio frequency pulses each having a third excitation angle to the specimen, with a third time period between third pulses, to obtain a second data set defining a second sample of the image space; applying one or more fourth radio frequency pulses each having a fourth excitation angle to the specimen, with a fourth time period between fourth pulses, to obtain a third data set defining a third sample of the image space; wherein the fourth excitation angle is different to the third excitation angle and/or the fourth time period is different to the third time period; calculating a magnetic field map data from at the three data sets; and outputting the magnetic field map data.
摘要翻译：映射发射到磁共振成像试样的射频磁场的方法。该方法包括以下步骤：在向所述样本应用施加具有第二激发角的一个或多个第二射频脉冲的所述第一脉冲之后，在所述第一时间段施加具有第一激发角的第一射频脉冲，在第二脉冲之间具有第二时间段，以获得定义图像空间的第一样本的第一数据集; 在第三脉冲之间具有第三时间周期，将具有第三激发角的一个或多个第三射频脉冲施加到所述样本，以获得限定所述图像空间的第二样本的第二数据集; 在第四脉冲之间具有第四时间段，将具有第四激发角的一个或多个第四射频脉冲施加到所述样本，以获得定义所述图像空间的第三样本的第三数据集; 其中所述第四激发角度与所述第三激发角度不同，和/或所述第四时间段不同于所述第三时间段; 从三个数据集计算磁场映射数据; 并输出磁场映射数据。

10. 发明申请

WO00072036A1 MAGNETIC RESONANCE IMAGING METHOD WITH SUB-SAMPLING 审中-公开
标题翻译：具有子采样的磁共振成像方法
公开(公告)号：WO00072036A1
公开(公告)日：2000-11-30
申请号：PCT/EP2000/004215
申请日：2000-05-04
IPC分类号： G01R33/54 , A61B5/055 , G01R33/3415 , G01R33/48 , G01R33/561
CPC分类号： G01R33/5611 , G01R33/5618 , G01R33/56554
摘要： The degree of sub-sampling in magnetic resonance imaging is such that the ensuing acquisition time for receiving (echo) series of magnetic resonance signals due to an individual RF excitation is shorter than the decay time of such magnetic resonance signals. Preferably, a segmented scan of the k space is performed, the number of segments and the number of lines scanned in each segment being adjustable and a predetermined total number of lines being scanned. Preferably, a small number of segments is used such that the acquisition time for receiving the magnetic resonance signals for the complete magnetic resonance image is shorter than the process time of the dynamic process involved.
摘要翻译：磁共振成像中的次采样程度使得由于单个RF激励而接收（回波）系列的磁共振信号的随后的采集时间比这些磁共振信号的衰减时间短。优选地，执行k空间的分段扫描，每个段中扫描的段的数量和行数是可调节的，并且预先扫描的总线数。优选地，使用少量的段，使得用于接收完整磁共振图像的磁共振信号的获取时间比所涉及的动态过程的处理时间短。

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