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1. 发明申请

WO2015114661A1 MYCOHERBICIDAL COMPOSITION FOR CONTROLLING LANTANA CAMARA WEED 审中-公开
标题翻译：用于控制LANTANA CAMARA WEED的MYCOHERBICIDAL组合物
公开(公告)号：WO2015114661A1
公开(公告)日：2015-08-06
申请号：PCT/IN2015/000044
申请日：2015-01-23
申请人： PRAHARAJU LAXMIHARAYANA , Ajay Kumar Singh
发明人： Ajay Kumar Singh
IPC分类号： A01N63/04 , A01P13/00
CPC分类号： A01N63/04 , C12P1/02 , C12R1/77
摘要： The invention relates to describe host-specific extracellular phytotoxins produced by Fusarium sp. That has a phytotoxic to Lantana camara . A novel method using phytotoxin has been developed for controlling Lantana camara , these phytotoxin can be used partially pure, as a cell- and spore-free filtrate, a crude filtrate, or a crude suspension of the culture and optionally along with other additives. 18s rRNAsequence analysis showed 93% nucleotide similarity of the Fungi to Fusarium sp. But also indicated nucleotide variation of this fungus from other known genus of Nectaria, Mariannaea, Volutella, Myrothecium . This analysis suggested that the novel fungus is closest to Fusarium sp. It is proposed that this is a new species of Fusarium sp.
摘要翻译：本发明涉及描述由镰刀菌属（Fusarium sp。）产生的宿主特异性细胞外植物毒素。对马缨丹具有植物毒性。已经开发了使用植物毒素的新方法来控制马缨丹，这些植物毒素可以部分纯化，作为细胞和无孢子滤液，粗滤液或培养物的粗悬浮液，以及任选与其它添加剂一起使用。 18s rRNA序列分析显示真菌与镰刀菌属的93％核苷酸相似性。而且还表明了来自其他已知的Nectaria，Mariannaea，Volutella，Myrothecium的这种真菌的核苷酸变异。该分析表明，新型真菌最接近镰刀菌这是一种新的镰刀菌属种。

2. 发明申请

WO2009034397A2 THE FUNGUS FUSARIUM SOLANI STRAIN 'FS-K' AND ITS USE IN THE BIOLOGICAL CONTROL OF PLANT PATHOGENS AND IN THE ENHANCEMENT OF PLANT GROWTH AND PRODUCTIVITY 审中-公开
标题翻译：真菌FANARIUM SOLANI菌株“FS-K”及其在植物病原体的生物控制中的应用，以及植物生长和生产力的提高
公开(公告)号：WO2009034397A2
公开(公告)日：2009-03-19
申请号：PCT/GR2008/000057
申请日：2008-09-10
申请人： PAPADOPOULOU, Kalliope , KAVROULAKIS, Nektarios , NTOUGIAS, Spyridon , ZERVAKIS, Georgios , EHALIOTIS, Constantinos
发明人： PAPADOPOULOU, Kalliope , KAVROULAKIS, Nektarios , NTOUGIAS, Spyridon , ZERVAKIS, Georgios , EHALIOTIS, Constantinos
IPC分类号： A01N63/04 , A01P3/00 , A01P5/00 , A01P15/00 , C05F11/08
CPC分类号： C05F11/08 , A01N63/04 , C05G3/02 , C12R1/77
摘要： This invention refers to the pure culture of a wild isolate of the fungal species Fusarium solani (code name: strain 'Fs-K') and to its use for the biological control of plant pathogens. The invention includes the mycelium of the strain 'Fs-K' and any genetic modification of it, the asexually produced conidia and chlamydospores of the strain 'Fs-K', and the cultures of the strain 'Fs-K' (grown on liquid or solid media) which contain the mycelium and/or the conidia and/or the chlamydospores, as well as any extract or ingredient which derives from the growth of the strain 'Fs-K' or from the growth of any genetic modification of it. The invention further includes organic substrates for plant growth, as well as any other substrate compositions suitable for the growth of fungi and/or plants which contain forms of the strain 'Fs-K' (i.e. any vegetative or reproductive structure of it which is involved in the biological control of diseases). The invention further includes the use of the strain 'Fs-K' for the enhancement of plant health and growth, for the protection of plants from pathogenic organisms, and for the regulation of the rhizosphere surroundings.
摘要翻译：本发明涉及真菌种Fusarium solani（代号：“Fs-K”）野生分离株的纯培养物及其用于植物病原体生物防治的用途。本发明包括菌株“Fs-K”的菌丝体及其任何遗传修饰，菌株“Fs-K”的无性生产的分生孢子和衣原体，以及菌株“Fs-K”的培养物（在液体上生长或固体培养基），以及来源于菌株“Fs-K”的生长或其任何遗传修饰的生长的任何提取物或成分，其含有菌丝体和/或分生孢子和/或衣原体孢子。本发明还包括用于植物生长的有机底物，以及适用于含有Fs-K菌株形式的真菌和/或植物生长的任何其它底物组合物（即涉及其的任何营养或生殖结构在疾病的生物防治中）。本发明还包括使用菌株“Fs-K”来增强植物健康和生长，用于保护植物免受致病生物体和用于调节根际环境。

3. 发明申请

WO1996032490A1 FERMENTATION FOR TAXOL PRODUCTION 审中-公开
标题翻译：紫杉醇生产发酵
公开(公告)号：WO1996032490A1
公开(公告)日：1996-10-17
申请号：PCT/CA1996000230
申请日：1996-04-12
申请人： NOVOPHARM LIMITED
发明人： NOVOPHARM LIMITED , DAHIYA, Jagroop, S.
IPC分类号： C12P17/02
CPC分类号： C12R1/645 , C12P17/02 , C12R1/77 , C12R1/80
摘要： Taxol producing microorganisms are isolated from the leaves, branches, twigs and bark of the ornamental yew shrub Taxus hicksii, and used in fermentation process to produce a biomass containing taxol in relatively large quantities. One specific such taxol-producing microorganism has been identified as a fungus of the species Alternaria alternata, of the order Fungus imperfecti, and herein designated Alternaria alternata (Taxus hicksii).
摘要翻译：紫杉醇生产微生物是从观赏到的红豆杉紫杉（Taxus hicksii）的叶，枝，树枝和树皮中分离出来的，并用于发酵过程中以相当大量生产含有紫杉醇的生物质。一种具体的这种紫杉醇生产微生物已经被鉴定为真菌非常优良品种链格孢（Alternaria alternata）的真菌，并且在这里被称为链格孢（Alternaria alternata）（Taxus hicksii））。

4. 发明申请

WO1995021910A1 MODIFICATION OF FILAMENTOUS MICROORGANISMS 审中-公开
标题翻译： FILAMENTOUS MICROORGANISMS的修改
公开(公告)号：WO1995021910A1
公开(公告)日：1995-08-17
申请号：PCT/GB1995000273
申请日：1995-02-10
申请人： ZENECA LIMITED , TRINCI, Anthony, Peter, Joseph , ROBSON, Geoffrey, David , WIEBE, Marilyn, Gail , NAYLOR, Thomas, William , WILLIAMSON, Trevor
发明人： ZENECA LIMITED
IPC分类号： C12N01/14
CPC分类号： C12R1/77 , A01H15/00 , A23J1/18 , A23L13/424 , A23L29/065 , A23L29/30 , A23L31/00 , C12N1/14 , Y10S435/911
摘要： Filamentous microorganisms of improved properties, for example growth rate, may be obtained by culturing a sample of desired morphology until a substantial proportion of the culture diverges from that morphology, selecting an organism from the culture at that stage which exhibits the desired morphology and repeating the process with the selected microorganism.
摘要翻译：可以通过培养所需形态的样品直到大部分培养物从该形态发散而从该形态中分离出来，从该培养物中选择具有所需形态的生物体并重复与所选择的微生物进行过程。

5. 发明申请

WO2019036777A1 PROCESSO DE OBTENÇÃO DE NANOPARTÍCULAS BIOSSINTÉTICAS DE PRATA, NANOPARTÍCULAS BIOSSINTÉTICAS DE PRATA OBTIDAS E SEU USO 审中-公开
公开(公告)号：WO2019036777A1
公开(公告)日：2019-02-28
申请号：PCT/BR2018/000050
申请日：2018-08-24
申请人： UNIVERSIDADE ESTADUAL DE CAMPINAS - UNICAMP
发明人： FAVARO, Wagner José , FERREIRA, Luiz Alberto Bandeira , GARCIA, Patrick Vianna , DE JESUS, Marcelo Bispo , CABALLERO, Nelson Eduardo Duran
IPC分类号： C12P3/00 , A61K33/38 , A61P35/00 , C12R1/77
CPC分类号： A61K33/38 , A61P35/00 , C12P3/00 , C12R1/77
摘要： A presente invenção refere-se a um processo de obtenção de nanopartículas biossintéticas de prata através da redução da prata por enzimas e substratos presentes em solução obtidas após a filtração da biomassa do fungo Fusarium oxysporum. Adicionamente, a presente invenção refere-se as referidas nanopartículas obtidas, assim como ao uso das mesmas para preparo de um medicamento para tratar câncer de bexiga.

6. 发明申请

WO2007027121A1 БИОЛОГИЧЕСКИ АКТИВНЫЙ ПИЩЕВОЙ ПРОДУКТ НА ОСНОВЕ МОЛОЧНОГО СЫРЬЯ (ВАРИАНТЫ) 审中-公开
标题翻译：生物活性乳制品
公开(公告)号：WO2007027121A1
公开(公告)日：2007-03-08
申请号：PCT/RU2005/000442
申请日：2005-08-31
申请人： ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ГЕЛЛА-ФАРМА" , ГРИГОРАШ Александр Ильич , МАКЛАНОВ Анатолий Иванович , САМОЙЛЕНКО Владимир Александрович , ОКУНЕВ Олег Николаевич
发明人： ГРИГОРАШ Александр Ильич , МАКЛАНОВ Анатолий Иванович , САМОЙЛЕНКО Владимир Александрович , ОКУНЕВ Олег Николаевич
IPC分类号： A23L1/29 , A61K36/06 , C12N1/14 , C12R1/77
CPC分类号： A23C9/1203 , A23C21/02 , A23L33/14 , A61K36/06 , C12N1/14 , C12R1/77 , A61K2300/00
摘要： Изобретение относится к пищевой промышленности и биотехнологии, а именно, к биологически активным пищевым продуктам, на основе молочного сырья, продуцируемыми грибом Fusarium sambucinum, которые могут быть использованы в диетическом питании для профилактики метаболического синдрома, при нарушениях работы желудочно-кишечного тракта (ЖКТ), печени, для укрепления иммунной системы человека. Предложен биологически активный пищевой продукт, который содержит культуральную жидкость и биомассу, полученную при культивировании грибов вида Fusarium sambucinum. В качестве молочного сырья используют подтворожную или подсырную молочную сыворотку или обезжиренное молоко. Готовый продукт имеет при влажности 6,5% следующий состав, мас. %: жиры – 10-15, причем жирно-кислотный состав составляет (в % от суммы жиров) – линолевая – 50-58, γ – линоленовая – 0,2-0,4, α – линоленовая – 0,4-0,7, эйкозатриеновая – 0,2-0,35, арахидоновая – 0,4-0,8; белки – 24-35, в том числе аминокислоты (в % от суммы белка) – 16-24; лактоза – 1-3; зола – 6-8; а также витамины – 300-500 мг/100г, в том числе витамин Е – 6-8 мг/100г, витамин В1 – 0,6-0,9 мг/100г, витамин В2 – 4-6 мг/100г, витамин В3 – 3,5-6,5, витамин В4 – 250-400 мг/100г. Как вариант, готовый продукт представляет собой отдельную от биомассы культуральную жидкость, характеризующуюся содержанием энниатина – 100-800 мг/л и ферментов: коллагеназы – 100-800 ед/мл, протеазы – 1-2 ед/мл, пектиназы – 0,4-0,8 ед/мл. Изобретение позволяет изменить белково-углеводный состав исходного молочного сырья, получить новые биологически активные добавки к пище с повышенным содержанием ценных биологически активных соединений (ферментов, полиненасыщенных жирных кислот, энниатина). Полученные продукты можно широко использовать для укрепления иммунной системы человека, профилактики метаболического синдрома, при нарушениях желудочно-кишечного тракта и печени.
摘要翻译：本发明涉及食品工业和生物工程，特别是涉及可被用于预防代谢综合征的饮食食物，针对胃肠道和肝脏功能障碍的食用镰刀菌真菌的生物活性的基于乳的食品。免疫系统推广。本发明的生物活性食品包括培养液和通过培养三叶草型真菌获得的生物质。牛奶原料以凝乳或奶酪乳清或无脂牛奶的形式体现。最终产品在6.5％的湿度：10-15质量％的脂肪中具有以下成分，其中脂肪酸组合物由（总脂肪含量的百分比）为50-58个，0.2-0.4-亚麻酸，0.4- 0.7亚麻油，0.2-0.35花生四烯酸; 蛋白质24-35，包括16-24（总蛋白质含量的％）氨基酸; 1-3乳糖; 含6-8mg / 100g维生素E，0.6-0.9维生素B1，4-6mg / 100g维生素B2，3.5-6.5mg / 100g维生素B1，维生素B1 B3和2590-400 mg / 100g维生素B4。在一个变体中，最终产物体现为与生物质分离的培养液的形式，其特征在于其含有100-800mg / l烯尼尼定和发酵剂：100-800单位/ ml，蛋白酶1-2 单位/ ml，果胶酶0.4-0.8单位/ ml。所述发明使得可以改变初始乳原料的蛋白质 - 碳水化合物组成，以获得具有增加的有价值的生物活性化合物（发酵剂，多不饱和脂肪酸和烯腈）含量的新型生物活性食品添加剂。因此可获得的产品可广泛用于促进人类免疫系统，用于预防代谢综合征和胃肠道和肝脏功能障碍。

7. 发明申请

WO2003064674A2 PROCESS FOR FERMENTATION OF PHYTOSTEROLS TO ANDROSTADIENEDIONE 审中-公开
标题翻译：将木霉素发酵成安非他酮的方法
公开(公告)号：WO2003064674A2
公开(公告)日：2003-08-07
申请号：PCT/CA2003/000131
申请日：2003-02-03
申请人： FORBES MEDI-TECH INC.
发明人： KUTNEY, James, P. , HERRINGTON, Edward, J. , SPASSOV, Grigor
IPC分类号： C12P33/00
CPC分类号： C12R1/77 , C12P33/00
摘要： A process of fermenting a phytosterol composition to produce androstenedione (androst-4-ene-3,17-dione) and subsequently androstadienedione (and rosta-1,4-diene,3,17-dione) comprises propagating a microbial culture of the genus Mycobacterium in a first nutrient medium, placing the microbial culture and the phytosterol composition in a bioreactor for a sufficient time to transform the composition substantially to androstenedione (the "AD solution"), propagating a fungal culture of the genus Fusarium in a second nutrient medium, and then injecting one or more of 1) Fusarium sp , or 2) the fungal culture medium into the bioreactor for a sufficient time to transform the AD solution to androstadienedione.
摘要翻译：发酵植物甾醇组合物以产生雄烯二酮（雄甾-4-烯-3,17-二酮）和随后的雄二烯二酮（和rosta-1,4-二烯，3,17-二酮）的方法包括将该属的微生物培养物在第一营养培养基中分支杆菌，将微生物培养物和植物甾醇组合物置于生物反应器中足够的时间以将组合物基本上转化成雄烯二酮（“AD溶液”），将真菌培养物在第二营养培养基中添加镰孢属镰孢，然后将1）镰刀菌sp1中的一种或多种，或2）真菌培养基注入生物反应器足够的时间将AD溶液转化成雄二烯二酮。

8. 发明申请

WO02024869A2 A FUNGL ELICITOR AND PROCESS FOR ITS PREPARATION 审中-公开
标题翻译：一个FUNGL ELICITOR AND PROCESS FOR IN PREPARATION
公开(公告)号：WO02024869A2
公开(公告)日：2002-03-28
申请号：PCT/IB2001/001850
申请日：2001-09-05
IPC分类号： A01N63/04 , C07K14/37 , C12P21/00 , C12N1/00
CPC分类号： C12R1/77 , A01N63/04 , C07K14/37 , C12P21/005
摘要： The present invention discloses a process for preparing an elicitor from Fusarium oxysporum and the product obtained by means of said process, i.e., an elicitor of systemic resistance in plants. The process is based upon successive extraction of cytoplasmatic fractions from the membrane and the wall of fungus F. oxysporum , mixture which constitutes the mentioned product.
摘要翻译：本发明公开了一种制备尖孢镰孢诱发剂的方法，以及通过所述方法获得的产物，即植物体系抗性诱发剂。该过程基于从膜和真菌壁的连续提取细胞质级分。氧肟，构成所述产物的混合物。

9. 发明申请

WO2012061331A3 FILAMENTOUS FUNGI AND METHODS FOR PRODUCING ISOPRENOIDS 审中-公开
标题翻译：真菌真菌和生产异丙酚的方法
公开(公告)号：WO2012061331A3
公开(公告)日：2012-07-26
申请号：PCT/US2011058700
申请日：2011-11-01
申请人： NOVOZYMES AS , HOHN THOMAS M
发明人： HOHN THOMAS M
IPC分类号： C12N1/15 , C12P23/00 , C12R1/77
CPC分类号： C12P5/007 , C12N9/88 , C12N15/80 , C12P5/002 , C12P2203/00 , C12R1/77 , C12Y402/03006 , C12Y402/03047
摘要： The present invention relates to the production of a isoprenoid products from a lignocellulosic feedstock. Specifically at least triple mutant of filamentous fungi having the isoprenoid pathway results in production of isoprenoid products in commercial quantities. One embodiment of the invention relates to producing the isoprenoid products at the site of the lignocellulosic feedstock to reduce costs of shipping the feedstock.
摘要翻译：本发明涉及从木质纤维素原料生产类异戊二烯产品。具体而言，具有异戊二烯通路的丝状真菌的至少三重突变体导致以商品数量生产类异戊二烯产品。本发明的一个实施方案涉及在木质纤维素原料的位置处产生类异戊二烯产物以降低运送原料的成本。

10. 发明申请

WO2012061331A2 FILAMENTOUS FUNGI AND METHODS FOR PRODUCING ISOPRENOIDS 审中-公开
标题翻译：丝状真菌和生产异戊二烯的方法
公开(公告)号：WO2012061331A2
公开(公告)日：2012-05-10
申请号：PCT/US2011/058700
申请日：2011-11-01
申请人： NOVOZYMES A/S , HOHN, Thomas, M.
发明人： HOHN, Thomas, M.
IPC分类号： C12N1/15 , C12P23/00 , C12R1/77
CPC分类号： C12P5/007 , C12N9/88 , C12N15/80 , C12P5/002 , C12P2203/00 , C12R1/77 , C12Y402/03006 , C12Y402/03047
摘要： The present invention relates to the production of a isoprenoid products from a lignocellulosic feedstock. Specifically at least triple mutant of filamentous fungi having the isoprenoid pathway results in production of isoprenoid products in commercial quantities. One embodiment of the invention relates to producing the isoprenoid products at the site of the lignocellulosic feedstock to reduce costs of shipping the feedstock.
摘要翻译：本发明涉及由木质纤维素原料生产类异戊二烯产物。具体而言，至少具有类异戊二烯途径的丝状真菌的三重突变体导致商品量的类异戊二烯产物的产生。本发明的一个实施方案涉及在木质纤维素原料的位置生产类异戊二烯产物以降低运输原料的成本。

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