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    • 10. 发明申请
    • IMPROVEMENTS IN OR RELATING TO POLYMERISABLE CEMENT COMPOSITIONS
    • 改善或相关于聚合水泥组合物
    • WO98030192A1
    • 1998-07-16
    • PCT/GB1998/000072
    • 1998-01-12
    • A61K6/087A61K6/083C04B28/28C08L33/14
    • C04B26/08A61K6/0038A61K6/0835A61K6/09C04B28/00C04B28/28C04B2111/00836C04B14/22C04B24/2641C04B40/065C08L33/00C08L75/16
    • A polymerisable cement composition, particularly for dental and biomedical uses, comprises a mixture of polymerisable monomer materials including between 5 and 95 % by weight tetrahydrofurfuryl methacrylate (THFMA), and at least 5 % by weight secondary monomer, preferably a dimethacrylate; and active filler material, preferably powdered fluoroaluminosilicate glass, capable of undergoing an acid-base reaction in the presence of water with acid or acid derivative groups in the composition. The composition is conveniently in the form of a resin-modified glass-ionomer cement or a compomer composition. The use of THFMA as a monomer material has a number of advantages. THFMA has low shrinkage on polymerisation, good biological acceptability and advantageous water uptake properties in comparison to other monomer systems. The invention also covers a method of preparing a polymerisable cement, and a method of dental treatment.
    • 可聚合的水泥组合物,特别是用于牙科和生物医学用途的可聚合水泥组合物包括可聚合单体材料的混合物,包括5至95重量%的甲基丙烯酸四氢糠酯(THFMA)和至少5重量%的二次单体,优选二甲基丙烯酸酯; 以及活性填料,优选粉末状氟铝硅酸盐玻璃,其能够在水与存在于组合物中的酸或酸衍生物基团的情况下进行酸碱反应。 该组合物方便地采用树脂改性的玻璃 - 离子交联聚合物水泥或聚合物组合物的形式。 使用THFMA作为单体材料具有许多优点。 与其它单体体系相比,THFMA在聚合时收缩率低,生物可接受性好,吸水性好。 本发明还涉及制备可聚合水泥的方法和牙科治疗方法。